Medication	Outcome	Number needed to treat
Acetaminophen, 1,000 mg	Pain free at 2 hours	12
Aspirin, 1,000 mg	Pain free at 2 hours	8
	Headache relief at 24 hours	7
Aspirin, 1,000 mg and metoclopramide, 10 mg	Pain free at 2 hours	9
	Headache relief at 24 hours	6
Frovatriptan (Frova), 2.5 mg	Pain free at 2 hours	8
Ibuprofen, 400 mg	Pain free at 2 hours	7
	Headache relief at 24 hours	4
Naproxen, 500 mg	Pain free at 2 hours	11
Naproxen/sumatriptan (Treximet), 500 mg/85 mg	Pain free at 2 hours	3
	Headache relief at 24 hours	5
Rizatriptan (Maxalt), 10 mg	Pain free at 2 hours	3
	Headache relief at 24 hours	3
Sumatriptan (Imitrex), 50 mg	Pain free at 2 hours	6
	Headache relief at 24 hours	6
Sumatriptan, 100 mg	Pain free at 2 hours	5
	Headache relief at 24 hours	5
Zolmitriptan (Zomig), 1 mg	Pain free at 2 hours	7
Zolmitriptan, 2.5 mg		5
Zolmitriptan, 5 mg		5
Zolmitriptan, 10 mg		3
Zolmitriptan (nasal spray), 5 mg		3