| Oral | | | | |
| Fluconazole (Diflucan) | Fingernails | 150 mg weekly until the entire nail grows out | 76% | $50 ($2,000) |
| Toenails | 150 mg weekly until the entire nail grows out | 31.2% | $100 ($4,500) |
| Itraconazole (Sporanox) | Fingernails | Two treatment pulses of 200 mg twice daily for one week separated by three weeks without treatment | 78% | $37 ($1,540) |
| Toenails | 200 mg daily for 12 weeks | 14% to 62.6% | $115 ($4,500) |
| Terbinafine | Fingernails | 250 mg daily for six weeks | 75% | $12 (—) |
| Toenails | 250 mg daily for 12 weeks | 38% to 76% | $20 (—) |
| Topical | | | | |
| Ciclopirox 8% | Fingernails | Applied once daily for 24 weeks | 5.5% | $20 (—) for one bottle |
| Toenails | Applied once daily for 48 weeks | 6% to 9% | $20 (—) for one bottle |
| Efinaconazole 10% (Jublia) | Toenails | Applied once daily for 48 weeks | 15.2% to 17.8% | — ($650 for one bottle) |
| Tavaborole 5% (Kerydin) | Toenails | Applied once daily for 48 weeks | 6.5% to 9.1% | $430 ($1,500) for one bottle |