MedicationLocationDosageClinical cure rateCost*
Oral
Fluconazole (Diflucan)Fingernails150 mg weekly until the entire nail grows out76%$50 ($2,000)
Toenails150 mg weekly until the entire nail grows out31.2%$100 ($4,500)
Itraconazole (Sporanox)FingernailsTwo treatment pulses of 200 mg twice daily for one week separated by three weeks without treatment78%$37 ($1,540)
Toenails200 mg daily for 12 weeks14% to 62.6%$115 ($4,500)
TerbinafineFingernails250 mg daily for six weeks75%$12 (—)
Toenails250 mg daily for 12 weeks38% to 76%$20 (—)
Topical
Ciclopirox 8%FingernailsApplied once daily for 24 weeks5.5%$20 (—) for one bottle
ToenailsApplied once daily for 48 weeks6% to 9%$20 (—) for one bottle
Efinaconazole 10% (Jublia)ToenailsApplied once daily for 48 weeks15.2% to 17.8%— ($650 for one bottle)
Tavaborole 5% (Kerydin)ToenailsApplied once daily for 48 weeks6.5% to 9.1%$430 ($1,500) for one bottle