Score	Components	Thresholds	Clinical significance
Lille Model for Alcoholic Hepatitis	Day 0: age, albumin, INR, creatinine, bilirubin, prothrombin time; day 7: bilirubin (https://www.mdcalc.com/lille-model-alcoholic-hepatitis)	Patient unresponsive to steroids (score ≥ 0.45)	Discontinue corticosteroids at day 718
Maddrey Discriminant Function	Prothrombin time, total bilirubin (https://www.mdcalc.com/maddreys-discriminant-function-alcoholic-hepatitis)	Severe disease (score ≥ 32)	Initiate corticosteroids19
MELD	Bilirubin, creatinine, INR, sodium (https://www.mdcalc.com/meld-score-model-end-stage-liver-disease-12-older)	Severe disease (score ≥ 21)	Initiate corticosteroids Predicts increased risk of in-hospital mortality if increases ≥ 2 in one week20 90-day mortality of 20% (sensitivity and specificity = 75%)21 28-day mortality of 30% to 50% (sensitivity = 86%, specificity = 48%)19,22
MELD-Na	Bilirubin, creatinine, INR, sodium (https://www.mdcalc.com/meldna-meld-na-score-liver-cirrhosis)	Transplant eligible (score ≥ 21)	Refer for liver transplant evaluation
Child-Pugh Score for Cirrhosis Mortality	Total bilirubin, albumin, INR, ascites burden, encephalopathy grade (https://www.mdcalc.com/child-pugh-score-cirrhosis-mortality)	Class A: score 5 or 6 Class B: score 7 to 9 Class C: score 10 to 15	Describes cirrhosis severity; less commonly used for prognosis given the advantages of MELD23