Disorder	Symptoms	Duration	Impairment	Specifiers	Differential diagnosis
					Substances or other medical conditions that can cause anxiety symptoms	Other mental disorders that can cause anxiety symptoms
Generalized anxiety disorder	Excessive anxiety and worry about events or activities Difficulty controlling worry Associated with one or more of the following symptoms: restlessness, easily fatigued, difficulty concentrating, irritability, muscle tension, or sleep disturbance	Occurring more days than not in past six months	Clinically significant distress or impaired functioning	—	Stimulant intoxication (e.g., cocaine, amphetamines) Depressant withdrawal (e.g., alcohol, benzodiazepines, opioids) Excessive caffeine Hyperthyroidism	Panic disorder Social anxiety disorder Obsessive-compulsive disorder Separation anxiety disorder Posttraumatic stress disorder Anorexia nervosa Somatic symptom disorder Body dysmorphic disorder Schizophrenia or delusional disorder
Panic disorder	Recurrent, unexpected panic attacks Abrupt surge of intense fear or discomfort peaking within minutes, during which four or more of the following symptoms occur: palpitations, sweating, trembling, shortness of breath, choking, chest pain, nausea, feeling faint or dizzy, chills or hot flashes, paresthesia, derealization or depersonalization, fear of losing control or dying	One or more attacks followed by at least one month of persistent worry about additional attacks and/or significant maladaptive change in behavior related to the attack	Clinically significant distress or impaired functioning	—	Stimulant intoxication (e.g., cocaine, amphetamines) Depressant withdrawal (e.g., alcohol, benzodiazepines, opioids) Hyperthyroidism Cardiopulmonary disease Excessive caffeine	Social anxiety disorder Specific phobia Obsessive-compulsive disorder Posttraumatic stress disorder Separation anxiety disorder
Separation anxiety disorder	Developmentally inappropriate anxiety or fear of separation from attachment figure, with at least three of the following: recurrent excessive distress when anticipating or experiencing separation; persistent and excessive worry about loss and harm; persistent and excessive worry about an event causing separation; persistent reluctance or refusal to go out because of separation fear; persistent and excessive fear or reluctance to be alone or without attachment figure; persistent reluctance or refusal to sleep away from home or be away from attachment figure; repeated separation nightmares; repeated complaints of physical symptoms when separation occurs or is anticipated	Lasts at least four weeks	Clinically significant distress or impaired functioning	—	—	Autism spectrum disorder Psychotic disorders Agoraphobia Generalized anxiety disorder
Social anxiety disorder	Marked fear or anxiety about one or more social situations in which the individual is exposed to possible scrutiny by peers Fear and anxiety out of proportion to actual threat Social situations almost always provoke fear and anxiety, which children may express by crying, throwing tantrums, freezing/not moving, clinging, shrinking, or failing to speak Social situations are avoided or endured with intense fear or anxiety	Persistent, typically lasting at least six months	Clinically significant distress or impaired functioning	Performance only (i.e., fear restricted to speaking or performing publicly)	Stimulant intoxication (e.g., cocaine, amphetamines) Depressant withdrawal (e.g., alcohol, benzodiazepines, opioids) If another medical condition is present (e.g., obesity; disfigurement from burns, injury, or congenital disorder) the fear, anxiety, or avoidance is clearly unrelated or is excessive	Panic disorder Body dysmorphic disorder Autism spectrum disorder
Specific phobia	Marked fear or anxiety about a specific object or situation Object or situation almost always provokes immediate fear or anxiety or is avoided or endured with intense fear and anxiety Fear or anxiety is out of proportion to the actual danger posed by the specific object or situation, and to the sociocultural context	Persistent, typically lasting at least six months	Clinically significant distress or impaired functioning	Animal Blood, injection, or injury Environmental Situational Other	—	Social anxiety disorder Separation anxiety disorder Obsessive-compulsive disorder Posttraumatic stress disorder Agoraphobia