MedicationDosage (mg)*Cost
Activella (amabelz, mimvey; estradiol/norethindrone acetate)0.5/0.1, 1/0.5
Oral
Once daily
$300 ($30)
Angeliq (estradiol/drospirenone)0.5/0.25, 1/0.5
Oral
Once daily
$200 (—)
Bijuva (estradiol/progesterone)1/100
Oral
Once daily
$240 (—)
Climara Pro (estradiol/levonorgestrel)0.045/0.015
Transdermal patch
Once weekly
$240 (—)
Combipatch (estradiol/norethindrone acetate)0.05/0.14, 0.05/0.25
Transdermal patch
Twice weekly
$250 (—)
Fyavolv (ethinyl estradiol/norethindrone acetate)0.0025/0.5
Oral
Once daily
— ($20)
Jinteli (ethinyl estradiol/norethindrone acetate)0.005/1
Oral
Once daily
$30 (—)
Prefest (estradiol/norgestimate)1/0.09
Oral
Once daily (estrogen alone for three days followed by estrogen/progestogen for three days, then repeat)
$215 (—)
Premphase (conjugated estrogen/medroxyprogesterone)0.625/5
Oral
Once daily (estrogen alone for days 1 through 14, then add progestogen for days 15 though 28)
$230 (—)
Prempro (conjugated estrogen/medroxyprogesterone)0.3/1.5, 0.45/1.5, 0.625/2.5, 0.625/5.0
Oral
Once daily
$225 (—)
Levonorgestrel-releasing intrauterine system (off-label use)52 mg; initially releases 21 mcg per day; declines to 11 mcg per day after five years
Inserted per manufacturer protocol for up to five years for heavy menstrual bleeding or eight years for contraception
$1,170 per device
Prometrium (micronized progesterone)200
Oral
Once daily for 12 days per month
$710 ($10)
Provera (medroxyprogesterone)2.5, 5, 10
Oral
Once daily for continuous use, or 10 to 14 days per month (starting day 15 through 19 if cyclic estrogen use)
$90 ($10)