Disease Medication Dosing Cure rate Common adverse effects
Giardiasis Metronidazole (Flagyl)* Adults
 500 mg twice daily for five to seven days or 250 mg three times daily for five to seven days
Infants, children, adolescents
 5 to 10 mg per kg three times daily for five to seven days; maximum of 250 mg per dose
80% when treating children
Diarrhea resolution11
Central nervous system effects, disulfiram-like reaction when mixed with alcohol, gastrointestinal discomfort, headache, metallic taste, nausea, pruritus
Nitazoxanide (Alinia) Individuals older than 11 years
 500 mg twice daily for three days
Children four to 11 years of age
 200 mg twice daily for three days
Children one to three years of age
 100 mg twice daily for three days
85% when treating children
Diarrhea resolution11
Abdominal pain, bright yellow urine, headache, nausea
Tinidazole§ Adults
 One 2-g dose
Children older than three years
 50 mg per kg in one dose, maximum of 2 g per dose
> 90% for children and adults
Parasitic cure12,13
Central nervous system effects, disulfiram-like reaction when mixed with alcohol, gastrointestinal discomfort, headache, metallic taste, nausea, pruritus
Cryptosporidiosis Nitazoxanide Patients older than 11 years
 500 mg twice daily for three days
Children four to 11 years of age
 200 mg twice daily for three days
Children one to three years of age
 100 mg twice daily for three days
80%14 Abdominal pain, bright yellow urine, headache, nausea
Cyclosporiasis Sulfamethoxazole/trimethoprim* Adults
 800 mg/160 mg twice daily for seven to 10 days
Children
 Limited data available
96%15 Anorexia, blood dyscrasias, Clostridioides difficile infection, diarrhea, hyperkalemia, hypersensitivity reactions, hypoglycemia, hyponatremia, kernicterus, liver injury, nausea, rash, vomiting
Trichinellosis Albendazole*|| Patients older than six years
 400 mg twice daily for eight to 14 days
Children one to six years of age
 5 to 10 mg per kg per day, divided twice daily for 10 to 15 days
Limited human data available Abdominal pain, elevated liver function test, headache, increased intracranial pressure, nausea, reversible alopecia, vomiting
Pinworm Albendazole* Patients older than two years and adolescents
 400 mg once; repeat in two to three weeks later
Children two years and younger
 200 mg once; repeat dose in three weeks
> 90%16 Abdominal pain, nausea, vomiting, headache, elevated findings on liver function tests, increased intracranial pressure, reversible alopecia
Mebendazole Adults
 100 mg once; repeat in two weeks
Children
 Limited data available but two years and older, 100 mg once; repeat in two weeks
>90%16 Abdominal pain, angioedema, anorexia, diarrhea, dizziness, fatigue, fever, flatulence, headache, hepatitis, nausea, vomiting, weakness
Pyrantel pamoate** Patients older than two years
 11 mg per kg once, followed by repeat dose two weeks later (maximum of 1 g per dose)
> 90%16 Nausea, vomiting, anorexia, abdominal cramps, diarrhea