Timing	Testing
Preexposure prophylaxis	Every three to four months HIV fourth-generation testing; results are not needed before cabotegravir (Apretude) injections Gonorrhea, chlamydia, and syphilis testing* Pregnancy testing Creatinine level, unless taking cabotegravir (Apretude) HIV RNA level if taking cabotegravir (Apretude) Annually Hepatitis C antibody testing
Initial HIV diagnosis and starting treatment	HIV RNA level CD4 cell count HIV RT-pro genotype testing STI and viral hepatitis screening Cryptococcal antigen testing if CD4 cell count < 100 cells per μL HIV integrase genotype testing if taking cabotegravir (Apretude) preexposure prophylaxis or if partner has failing regimen with integrase strand transfer inhibitor Human leukocyte antigen B*5701 testing if starting abacavir (Ziagen)
During treatment	HIV RNA level every three months until suppressed, then every six months CD4 cell count every six months until 250 cells per μL for one year, then stop if RNA level is suppressed STI and viral hepatitis screening HIV RT-pro genotype testing if switching to injectable medications
Virologic failure	HIV RNA level CD4 cell count HIV RT-pro genotype testing STI and viral hepatitis screening HIV integrase genotype testing if failing regimen includes an integrase strand transfer inhibitor Viral trophism testing if switching to maraviroc (Selzentry)