Stage	Symptoms	Time frame	Approximate prevalence in people with alcohol use disorder	Treatment
1	Minor withdrawal symptoms: abdominal discomfort, anorexia, diaphoresis, headache, insomnia, mild anxiety, palpitations, tachycardia, tremulousness	6 to 12 hours since last drink; symptoms often resolve within 24 to 48 hours	50%	Oral benzodiazepines (e.g., diazepam, chlordiazepoxide) using fixed-dosing or symptom-triggered therapy
2	Hyperactivity; insomnia; visual, tactile, or auditory hallucinations; visual hallucinations commonly involve seeing insects or animals (e.g., misinterpreting that their urinary catheter is a snake)	10 to 30 hours since last drink; resolves within 48 hours if withdrawal is treated or does not progress	5%	Oral or intravenous benzodiazepines or phenobarbital using front-loading, fixed-dosing, or symptom-triggered therapy
3	Generalized tonic-clonic seizures that can be isolated or occur in clusters; hyperactivity; insomnia; visual, tactile, or auditory hallucinations	12 to 48 hours since last drink, but may present as early as 2 hours after last drink	10%	Intravenous benzodiazepines or phenobarbital using front-loading therapy
4	Delirium tremens, including agitation, diaphoresis, disorientation, hallucinations, hyperactivity, hypertension, hyperthermia, tachycardia, tachypnea	72 to 96 hours since last drink; symptoms may last up to 7 days	5%	Intensive care unit management with intravenous benzodiazepines and phenobarbital