Red flags (TUNA FISH mnemonic)
Trauma
Unexplained weight loss
Neurologic findings
Age > 50 years
Fever
Intravenous drug use
Steroid use
History of cancer
Yellow flags
Belief that pain and activity are harmful
Compensation claims and prolonged sick leave
Depressed mood and social withdrawal
Exaggerated illness response
Lack of support
Overprotective family