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Am Fam Physician. 2025;111(3):263-264

Author disclosure: No relevant financial relationships.

DrugDosageDose formCost*
Berdazimer (Zelsuvmi)Apply once daily for up to 12 weeksTopical gel$700

Berdazimer (Zelsuvmi) is a topical, nitric oxide–releasing agent that is theorized to treat molluscum contagiosum through antiviral and immunomodulatory properties.1 It is labeled for use in adults and children older than 1 year.2 Berdazimer consists of two components: the active ingredient, berdazimer sodium, binds nitric oxide, and a hydrogel acts as a proton donor. Combining these two components before application forms the therapeutic agent that releases nitric oxide from the berdazimer sodium polymer in a controlled, localized, topical application.1

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STEPS new drug reviews cover Safety, Tolerability, Effectiveness, Price, and Simplicity. Each independent review is provided by authors who have no financial association with the drug manufacturer.

This series is coordinated by Allen F. Shaughnessy, PharmD, assistant medical editor.

A collection of STEPS published in AFP is available at https://www.aafp.org/afp/steps.

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