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The first patient I examined as a medical student had a large and easily palpable liver. The etiology was cirrhosis due to hepatitis C, secondary to injection drug use. I was just beginning to learn physical examination skills, and the teaching strategy my instructor, Dr G (a family physician), used was one I still find effective: linking a learner’s understanding of a disease and its treatment to the examination and compassionate care of a memorable patient.

Hepatitis C was not treatable then, but it is now. Our approaches to and options for managing liver conditions continue to change, which is why our editorial board decided that this edition of FP Essentials™ should provide updates on four topics related to liver disease.

Section One covers the interpretation of common liver test results and the evaluation and management of patients with abnormal liver test results. Section Two focuses on hepatitis C, including management with direct-acting antiviral drugs. Section Three addresses nonalcoholic fatty liver disease, which is increasing in prevalence in parallel along with obesity and metabolic syndrome. Section Four discusses management of cirrhosis and its complications.

We hope you find this edition useful in your practice. When you have finished studying this edition and are ready to submit your posttest answers, please tell us what was most useful and what we can do to improve. We also look forward to hearing your ideas for topics you would like covered in future editions.

Each year, all manuscripts submitted for publication in FP Essentials undergo peer review by subject matter experts, a process that helps ensure the quality and clinical usefulness of our published monographs. Below, we acknowledge the individuals who performed those reviews for monographs published in 2021, and offer our sincere thanks for the time and effort they devoted to the peer review process. Barry D. Weiss, MD, FAAFP, FP Essentials Medical Editor

Karl T. Rew, MD, Associate Medical Editor
Associate Professor, Department of Family Medicine
University of Michigan Medical School, Ann Arbor

Each year, all manuscripts submitted for publication in FP Essentials undergo peer review by subject matter experts, a process that helps ensure the quality and clinical usefulness of our published monographs. Below, we acknowledge the individuals who performed those reviews for monographs published in 2021, and offer our sincere thanks for the time and effort they devoted to the peer review process. Barry D. Weiss, MD, FAAFP, FP Essentials Medical Editor

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