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Icosapent Ethyl (Vascepa) for Hyperlipidemia/Hypercholesterolemia to Reduce Risk of ... Restricted content. Login required.

Jan 15, 2021 - Icosapent ethyl is safe, well tolerated and effective in preventing ischemic events including stroke and heart attack.

American Family Physician : STEPS

https://www.aafp.org/afp/2021/0115/p117.html

Small Reduction in Cardiovascular Outcome After Ischemic Stroke with Lower LDL Target, ... Restricted content. Login required.

Aug 15, 2020 - A lower LDL target slightly reduced the likelihood of a broad composite outcome (number needed to treat [NNT] = 43 over 3.5 years), largely by reducing nonfatal strokes (NNT = 77; statistical significance not reported).

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0815/p247.html

Statins Ineffective for Primary Prevention of Cardiovascular Disease in Patients 75 ...

Apr 1, 2019 - In this retrospective study, statin treatment in patients 75 years or older without preexisting CVD did not change the likelihood of developing CVD or reduce any-cause mortality. However, patients 75 to 84 years of age with diabetes mellitus benefitted from treatment. These results ...

American Family Physician : POEMs

https://www.aafp.org/afp/2019/0401/p461.html

Statins in Persons at Low Risk of Cardiovascular Disease - Medicine by the Numbers - ...

Nov 1, 2017 - Despite the small reductions in nonfatal heart attacks and strokes, statins were not associated with a reduction in serious illness overall.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2017/1101/od1.html

Niacin Does Not Decrease Mortality in Patients with Coronary Artery Disease or Low HDL ...

Jul 15, 2017 - We are now flush with data about the effects of niacin in patients with elevated cholesterol levels. Despite its ability to raise high-density lipoprotein (HDL) serum cholesterol levels, it does not add additional mortality or morbidity benefit to statin treatment. Patients with ...

American Family Physician : POEMs

https://www.aafp.org/afp/2017/0715/p129.html

Hyperlipidemia: Drugs for Cardiovascular Risk Reduction in Adults - American Family ...

Jan 15, 2017 - Guidelines from the American College of Cardiology/American Heart Association (ACC/AHA) and the U.K. National Institute for Health and Care Excellence (NICE) indicate that lipid-lowering drugs have benefit for primary and secondary prevention of atherosclerotic cardiovascular disease ...

American Family Physician : Article

https://www.aafp.org/afp/2017/0115/p78.html

Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: ...

Jan 15, 2017 - The USPSTF recommends that adults without a history of cardiovascular disease (CVD) (i.e., symptomatic coronary artery disease or ischemic stroke) use a low- to moderate-dose statin for the prevention of CVD events and mortality when all of the following criteria are met: (1) they are ...

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2017/0115/od1.html

Evolocumab (Repatha) for the Treatment of Hyperlipidemia - STEPS - American Family ...

Nov 15, 2016 - Evolocumab is generally safe and effective at lowering serum LDL cholesterol levels for select patients who need marked cholesterol reduction and can tolerate injections. However, it remains unknown whether evolocumab prevents premature death from cardiovascular events.

American Family Physician : STEPS

https://www.aafp.org/afp/2016/1115/p843.html

Should Family Physicians Follow the New ACC/AHA Cholesterol Treatment Guideline? Not ...

Aug 15, 2014 - The recommendations should have paid more attention to the inherent uncertainties in risk estimates and the importance of individual patient circumstances and preferences.

American Family Physician : Editorials: Controversies in Family Medicine

https://www.aafp.org/afp/2014/0815/p223.html

Should Family Physicians Follow the New ACC/AHA Cholesterol Treatment Guideline? Yes: ...

Aug 15, 2014 - The recommendations appropriately focus treatment on those most likely to benefit.

American Family Physician : Editorials: Controversies in Family Medicine

https://www.aafp.org/afp/2014/0815/p212.html

The JUPITER Study: Biomarkers Plus Statin vs. Lifestyle Modification for Preventing ...

Mar 15, 2009 - ...COLIN KOPES-KERR, MD, Santa Rosa Family Medicine Residency, Santa Rosa, California MARK EBELL, MD, MS, University of Georgia, Athens, Georgia Am Fam Physician. 2009 Mar 15;79(6):438-442. The JUPITER (Justification for the Use of Statins in Prevention: An Intervention Trial...

American Family Physician : Editorials

https://www.aafp.org/afp/2009/0315/p438.html

Optimal Management of Cholesterol Levels and the Prevention of Coronary Heart Disease ...

Jan 15, 2002 - Coronary heart disease, the leading cause of death in women, is largely preventable. Lifestyle modifications (e.g., diet and exercise) are the cornerstone of primary and secondary prevention. Elevated levels of low-density lipoprotein cholesterol and triglycerides and low levels of ...

American Family Physician : Article

https://www.aafp.org/afp/2002/0115/p217.html

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