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Medicine by the numbers

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Placental Alpha Macroglobulin-1 (PartoSure) Immunoassay to Assess the Risk of ... Restricted content. Login required.

Sep 1, 2020 - Placental alpha macroglobulin-1 (PartoSure) is an immunoassay that measures the presence of placental alpha macroglobulin-1 (PAMG-1). PartoSure is used to assess the risk of spontaneous preterm birth and may be a useful adjunct to determine which patients with threatened preterm labor ...

American Family Physician : Diagnostic Tests: What Physicians Need to Know

https://www.aafp.org/afp/2020/0901/p269.html

Depression Following Acute Coronary Syndrome Events: Screening and Treatment Guidelines...

Jun 15, 2019 - The purpose of this guideline is to provide recommendations that are relevant to primary care for the screening and treatment of depression in patients following an acute coronary syndrome (ACS) event.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2019/0615/od2.html

Applying a Clinical Decision Rule for CAD in Primary Care to Select a Diagnostic Test ...

May 1, 2019 - Using the INTERCHEST chest pain decision rule to decide next steps when a patient presents to a primary care physician with chest pain.

American Family Physician : Point-of-Care Guides

https://www.aafp.org/afp/2019/0501/p584.html

Metformin to Prevent Diabetes in Patients at Increased Risk - Cochrane for Clinicians -... Restricted content. Login required.

Nov 1, 2020 - In patients at increased risk of developing type 2 diabetes, metformin reduces the risk (number needed to treat [NNT] = 7; 95% CI, 6 to 10) compared with counseling on standard diet and exercise.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2020/1101/p531.html

The Effectiveness of Outpatient Telehealth Consultations - Implementing AHRQ Effective ...

Nov 1, 2019 - Telehealth consultations improve clinical outcomes in the areas of wound care, psychiatry, and certain chronic conditions.

American Family Physician : Implementing AHRQ Effective Health Care Reviews

https://www.aafp.org/afp/2019/1101/p575.html

Acupuncture Not Supported By Strong Scientific Evidence - Letters to the Editor - ...

Mar 15, 2020 - ...Original Article: Acupuncture for Pain; and Integrating Medical Acupuncture into Family Medicine Practice [Editorial] Issue Date: July 15, 2019 See additional reader comments at: https://www.aafp.org/afp/2019/0715/p89.html; and https://www.aafp.org/afp/2019/0715/p76.html To the...

American Family Physician : Letter

https://www.aafp.org/afp/2020/0315/p326.html

Acute Altitude Illness: Updated Prevention and Treatment Guidelines from the Wilderness... Restricted content. Login required.

Apr 15, 2020 - Acute altitude illness comprises acute mountain sickness, high altitude cerebral edema, and high altitude pulmonary edema. The Wilderness Medical Society has updated prevention and treatment guidelines on acute altitude illness.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2020/0415/p505.html

CT Colonography for Colorectal Cancer Screening - Diagnostic Tests: What Physicians ... Restricted content. Login required.

Jan 1, 2021 - Computed tomography colonography performs well for colorectal cancer screening. Long-term studies are needed to demonstrate its impact on patient morbidity and mortality, as well as to determine the risks, benefits, and costs.

American Family Physician : Diagnostic Tests: What Physicians Need to Know

https://www.aafp.org/afp/2021/0101/p55.html

Small Reduction in Cardiovascular Outcome After Ischemic Stroke with Lower LDL Target, ... Restricted content. Login required.

Aug 15, 2020 - A lower LDL target slightly reduced the likelihood of a broad composite outcome (number needed to treat [NNT] = 43 over 3.5 years), largely by reducing nonfatal strokes (NNT = 77; statistical significance not reported).

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0815/p247.html

ACIP Approves 2020 Adult and Childhood/Adolescent Immunization Schedules - Practice ...

Feb 15, 2020 - The 2020 adult and childhood/adolescent immunization schedules have been approved by the Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2020/0215/p251.html

Respiratory Tract Infections - American Family Physician

Feb 1, 2021 - ...11/01/2020 Antibiotics for Acute Bronchitis [Medicine by the Numbers] new 10/01/2019 Antibiotics for Acute Rhinosinusitis in Adults [Medicine by the Numbers] 09/01/2019 Treatment of the Common Cold 05/15/2019 Chronic Cough After Acute Viral Bronchiolitis: Suggestions...

American Family Physician : AFP By Topic

https://www.aafp.org/afp/topicModules/viewTopicModule.htm?topicModuleId=29

Gabapentinoids for Pain: Potential Unintended Consequences - Editorials - American ...

Dec 1, 2019 - The widespread and often indiscriminate prescribing of gabapentinoids is not supported by robust evidence, and it carries known and unknown risks.

American Family Physician : Editorials

https://www.aafp.org/afp/2019/1201/p672.html

Colorectal Cancer Screening: ACP Guidance Statements - Practice Guidelines - American ... Restricted content. Login required.

Aug 15, 2020 - The American College of Physicians developed a consensus statement for colorectal cancer screening of average-risk adults based on their review of six independent guidelines and supporting evidence.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2020/0815/p250.html

Antepartum Omega-3 Fatty Acid Intake and Length of Gestation - Cochrane for Clinicians ...

Jan 1, 2020 - Omega-3 fatty acids, whether taken as supplements or consumed as part of the diet, reduce the risk of preterm birth (number needed to treat = 68) and early preterm birth (number needed to treat = 55).

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2020/0101/p17.html

Combined Hormonal Contraceptives for Heavy Menstrual Bleeding - Cochrane for Clinicians...

Dec 1, 2019 - Combined oral contraceptives decrease the number of women reporting menorrhagia over six months compared with placebo (absolute risk reduction = 36.7%; number needed to treat = 2.7).

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/1201/p677.html

Antihypertensive Drug Therapy for Mild to Moderate Hypertension During Pregnancy - ...

Oct 1, 2019 - Compared with placebo, antihypertensive drug therapy for mild to moderate hypertension (defined by the authors as a blood pressure of 140 to 169 mm Hg systolic or 90 to 109 mm Hg diastolic) caused by chronic hypertension, gestational hypertension, or preeclampsia during pregnancy does ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/1001/p403.html

Pharmacologic Therapy for Heart Failure - FPIN's Help Desk Answers - American Family ...

Jul 1, 2019 - Compared with monotherapy, the combination of an ACE inhibitor and an ARB has not been shown to improve cardiovascular or overall mortality in patients with symptomatic heart failure. The combination is associated with an increased number of adverse drug effects.

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2019/0701/p49.html

Diary of a Family Physician - Oct 15, 2020 - American Family Physician Restricted content. Login required.

Oct 15, 2020 - First-person accounts from the front lines of family medicine.

American Family Physician : Diary of a Family Physician

https://www.aafp.org/afp/2020/1015/p460.html

Lithium for Acute Mania - Cochrane for Clinicians - American Family Physician Restricted content. Login required.

May 1, 2020 - Lithium is more effective at inducing a reduction of at least 50% on the validated Young Mania Rating Scale compared with placebo (number needed to treat [NNT] = 6; 95% CI, 5 to 8; six studies; n = 1,707).

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2020/0501/p528.html

One Month of Dual Antiplatelet Therapy Followed by Clopidogrel Alone is Superior to 12 ...

Dec 15, 2019 - This study found that one month of dual antiplatelet therapy (aspirin plus clopidogrel or prasugrel [Effient]) followed by clopidogrel monotherapy for up to five years is both noninferior and superior to 12 months of dual antiplatelet therapy followed by aspirin for up to five years for...

American Family Physician : POEMs

https://www.aafp.org/afp/2019/1215/od5.html

Therapies for COPD Exacerbations in Adults - Implementing AHRQ Effective Health Care ... Restricted content. Login required.

May 1, 2020 - What are the benefits and harms of pharmacologic and nonpharmacologic treatments for exacerbations of chronic obstructive pulmonary disease (COPD) in adults?

American Family Physician : Implementing AHRQ Effective Health Care Reviews

https://www.aafp.org/afp/2020/0501/p557.html

Treatment of Threatened Miscarriage with Progestogens - Cochrane for Clinicians - ...

Sep 1, 2019 - Progestogens reduce the risk of miscarriage when compared with placebo in patients with threatened miscarriage (number needed to treat [NNT] = 10.) Use of progestogens poses no significant risks to mother or baby.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0901/p279.html

Integrating Medical Acupuncture into Family Medicine Practice - Editorials - American ...

Jul 15, 2019 - Acupuncture is an evidence-based therapy to reduce pain that can meet patient demand for nonpharmacologic treatment. Now is the time to offer training in medical acupuncture to more family physicians.

American Family Physician : Editorials

https://www.aafp.org/afp/2019/0715/p76.html

Skin Conditions - American Family Physician

Feb 1, 2021 - This collection features AFP content on common skin conditions and related issues, including acne, dermatitis, dermatologic emergencies, generalized rash, lichen planus, nail disorders, newborn skin, office procedures, premalignant lesions, and psoriasis. This collection features AFP ...

American Family Physician : AFP By Topic

https://www.aafp.org/afp/topicModules/viewTopicModule.htm?topicModuleId=21

Newborn Circumcision Techniques and Medical Ethics - Letters to the Editor - American ...

Jan 15, 2021 - ...are virtually always treatable and are relatively uncommon in boys regardless of circumcision status. The cited report suggests that the number of circumcisions needed to prevent one (likely treatable) UTI is approximately 100. Penile cancer is one of the rarest malignancies for...

American Family Physician : Letter

https://www.aafp.org/afp/2021/0115/p69.html

Beware of the Differing Definitions for the False-Positive Rate - Letters to the Editor...

Jan 1, 2021 - ...rates in antibody testing in their Letter to the Editor. We agree that testing in low-prevalence populations will result in a large number of false-positive test results. Because multiple definitions of the false-positive rate exist, it is important to state which definition is...

American Family Physician : Letter

https://www.aafp.org/afp/2021/0101/p7.html

Potential Drug Interactions in Patients Taking Oral Contraceptive Pills - Letters to ...

Nov 15, 2019 - ...women for other conditions, such as migraines and mood disorders. I expect that the absolute number of patients who are taking these drugs while taking OCPs is probably a lot less than the number who might be prescribed an antibiotic while taking warfarin (Coumadin), for example....

American Family Physician : Letter

https://www.aafp.org/afp/2019/1115/p599.html

Understanding the High Cost of Insulin: What Family Physicians Can Do to Help Our ...

Apr 1, 2019 - Through clinical and system-level interventions, family physicians can push back against the high cost of insulin and help patients with type 2 diabetes afford these essential medications.

American Family Physician : Editorials

https://www.aafp.org/afp/2019/0401/p416.html

Lasmiditan (Reyvow) for the Treatment of Acute Migraine - STEPS - American Family ... Restricted content. Login required.

Dec 15, 2020 - Lasmiditan is a costly alternative to other more extensively studied medications for acute migraine. It should be reserved for those patients who lack relief with other available agents or who cannot tolerate other abortive medications.

American Family Physician : STEPS

https://www.aafp.org/afp/2020/1215/p756.html

AFP 2020: Reflections, New Fellows, Updates, and AFP Statistics - Editorials - American...

Oct 15, 2020 - This editorial highlights the top 20 AFP articles of 2019, provides an update on AFP's statistics for print circulation and website visits, and thanks our peer reviewers.

American Family Physician : Editorials

https://www.aafp.org/afp/2020/1015/p457.html

Pain: Chronic - American Family Physician

Feb 1, 2021 - This collection features AFP content on chronic pain and related issues, including end-of-life care, NSAIDs, and opioid therapy. This collection features AFP content on chronic pain and related issues, including end-of-life care, NSAIDs, and opioid therapy.

American Family Physician : AFP By Topic

https://www.aafp.org/afp/topicModules/viewTopicModule.htm?topicModuleId=61

Depression After ACS, Amenorrhea, Physical Activity, Heart Failure, Erythema Multiforme...

Jan 15, 2020 - Key clinical questions and their evidence-based answers directly from the journal's content, written by and for family physicians.

American Family Physician : AFP Clinical Answers

https://www.aafp.org/afp/2020/0115/p75.html

Health Equity in Preventive Services: The Role of Primary Care - Editorials - American ...

Sep 1, 2020 - Groups that are least likely to receive preventive screening or to have timely, high-quality follow-up include those with limited or no health insurance, limited education and literacy, and no regular source of care, as well as those who are subject to discrimination based on racial, ...

American Family Physician : Editorials

https://www.aafp.org/afp/2020/0901/p264.html

Diverticulitis: Predicting Which Patients with Acute Abdominal Pain Have the Disease - ... Restricted content. Login required.

Sep 15, 2020 - Is it possible to determine which patients with acute abdominal pain are likely to have diverticulitis and therefore do not require imaging?

American Family Physician : Point-of-Care Guides

https://www.aafp.org/afp/2020/0915/p371.html

Corticosteroids for Hospitalized Patients with Community-Acquired Pneumonia - Cochrane ... Restricted content. Login required.

Sep 1, 2020 - For adults hospitalized with severe CAP, the use of corticosteroids may reduce the likelihood of mortality.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2020/0901/p272.html

Screening and Behavioral Counseling Interventions to Reduce Unhealthy Alcohol Use in ...

Jun 15, 2019 - The USPSTF recommends screening for unhealthy alcohol use in primary care settings in adults 18 years or older, including pregnant women, and providing persons engaged in risky or hazardous drinking with brief behavioral counseling interventions to reduce unhealthy alcohol use.

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2019/0615/od1.html

Heavy Menstrual Bleeding in Premenopausal Patients and the Role of NSAIDs - Cochrane ... Restricted content. Login required.

Aug 1, 2020 - NSAIDs are effective for reducing heavy menstrual bleeding in premenopausal patients with menorrhagia when compared with placebo.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2020/0801/p147.html

Emotional Support Animals: Considerations for Documentation - Curbside Consultation - ... Restricted content. Login required.

Mar 1, 2020 - Companion animals are increasingly viewed as part of the family, and studies show many mental and physical benefits of pet ownership. Federal regulations require patients to obtain health care professional documentation for emotional support animals to allow these animals to accompany ...

American Family Physician : Curbside Consultation

https://www.aafp.org/afp/2020/0301/p302.html

Bridging Warfarin Before Colonoscopy in Patients with Atrial Fibrillation - FPIN's ...

Apr 15, 2019 - A limited number of trials that examined the risk of temporary interruption of anticoagulation before a variety of procedures did not find a reduction in the risk of stroke, but they did show an increased risk of bleeding events and venous thromboembolism (VTE) in patients who were ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2019/0415/p519.html

Antiemetics for Acute Gastroenteritis in Children - FPIN's Clinical Inquiries - ... Restricted content. Login required.

Jul 1, 2020 - Oral ondansetron (Zofran) may be given to children presenting to the emergency department with vomiting and mild to moderate dehydration from acute gastroenteritis. It reduces hospital admissions and the need for intravenous hydration.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2020/0701/p51.html

Point-of-Care Ultrasonography: An Effective Tool When Used Appropriately - Letters to ...

Feb 1, 2019 - Letters to the Editor from AFP readers regarding previously published articles.

American Family Physician : Letter

https://www.aafp.org/afp/2019/0201/p143.html

Management of Acute Pain from Musculoskeletal Injuries: Guidance for Family Physicians ...

Dec 1, 2020 - Primary care plays a large role in the management of acute pain; therefore, the American College of Physicians and the American Academy of Family Physicians developed a clinical practice guideline for the nonpharmacologic and pharmacologic management of acute pain from non–low back, ...

American Family Physician : Editorials

https://www.aafp.org/afp/2020/1201/p649.html

Anticoagulation for the Long-term Treatment of VTE in Patients with Cancer - Cochrane ...

Jun 1, 2019 - Low-molecular-weight heparin (LMWH), vitamin K antagonists, and direct oral anticoagulants, when used to prevent recurrent VTE, have a similar impact on all-cause mortality.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0601/p676.html

Positional Therapy for Obstructive Sleep Apnea - Cochrane for Clinicians - American ...

Jan 1, 2020 - Positional therapy for OSA reduces scores on the apnea-hypopnea index (AHI) and Epworth Sleepiness Scale compared with no treatment. Although continuous positive airway pressure (CPAP) improves AHI scores more than positional therapy, patients seem to better tolerate positional therapy ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2020/0101/p16.html

Antidepressants Plus Benzodiazepines for Adults with Major Depression - Cochrane for ... Restricted content. Login required.

May 1, 2020 - A combination of tricyclic antidepressants and benzodiazepines is more effective for major depression in adults than tricyclic antidepressants alone in the first four weeks of treatment.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2020/0501/p527.html

Music Therapy for Depression - Cochrane for Clinicians - American Family Physician Restricted content. Login required.

Mar 1, 2020 - Moderate-quality evidence shows that music therapy added to standard care is more effective in the first three months than standard care alone for depressive symptoms based on clinician-rated outcomes and patient-reported outcomes.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2020/0301/p273.html

Denosumab No Better than Bisphosphonates for Preventing Fracture, and the Cost Is Much ... Restricted content. Login required.

Sep 15, 2020 - This meta-analysis found no evidence that the monoclonal antibody denosumab reduces the risk of fracture more than bisphosphonates.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0915/p375a.html

Positive Chest Radiograph Findings Are Not Enough to Warrant Antibiotics in Patients ...

Jan 1, 2020 - ...Editor’s Note: Dr. Ebell is Deputy Editor for Evidence-Based Medicine for AFP. References 1. Ebell MH, Radke T. Antibiotic use for viral acute respiratory tract infections remains common. Am J Manag Care. 2015;21(10):e567–e575. 2. Van Vugt S, Broekhuizen BD, Lammens C, et al. Use of...

American Family Physician : Letter

https://www.aafp.org/afp/2020/0101/p5.html

Alcohol Use Disorder: Pharmacologic Treatment Options - FPIN's Clinical Inquiries - ... Restricted content. Login required.

Oct 1, 2020 - Acamprosate and naltrexone should be used as first-line agents for treatment of alcohol use disorder and are effective for reducing relapse rates. Agent selection should be based on comorbid conditions and adherence to the dosing regimen.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2020/1001/od1.html

Use of Amphetamines for Attention Deficit/Hyperactivity Disorder in Adults - Cochrane ...

Sep 1, 2019 - Amphetamines provide a clinician-rated 30% or greater reduction in ADHD symptoms when compared with placebo (number needed to treat = 5).

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0901/p278.html

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