Practice Guidelines - Nov 15, 2004 - American Family Physician
Nov 15, 2004 - ...a small opening between the two upper chambers of the heart, or the atria. The opening normally closes shortly after birth, but does not close in up to 25 percent of people. Current thinking is that patients with a PFO who have had a stroke with no known cause and received treatment...
American Family Physician : Practice Guidelines
https://www.aafp.org/afp/2004/1115/p2026.html
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