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Medicine by the numbers

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Should We Treat Moderately Elevated Triglycerides? No: Reducing Moderately Elevated ...

Feb 1, 2011 - Moderately elevated triglyceride levels have not been established as an independent risk factor for CHD. More importantly, the lowering of moderately elevated triglyceride levels with drug therapy has not been shown to decrease the rate of CHD for primary prevention in otherwise healthy...

American Family Physician : Editorials: Controversies in Family Medicine

https://www.aafp.org/afp/2011/0201/p246.html

Small Reduction in Cardiovascular Outcome After Ischemic Stroke with Lower LDL Target, ... Restricted content. Login required.

Aug 15, 2020 - A lower LDL target slightly reduced the likelihood of a broad composite outcome (number needed to treat [NNT] = 43 over 3.5 years), largely by reducing nonfatal strokes (NNT = 77; statistical significance not reported).

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0815/p247.html

Statin Therapy in Patients with Type 2 Diabetes - FPIN's Clinical Inquiries - American ...

Sep 1, 2005 - Based on current evidence, statin therapy should be offered to all patients with type 2 diabetes who are known to have coronary artery disease.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2005/0901/p866.html

Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: ...

Jan 15, 2017 - The USPSTF recommends that adults without a history of cardiovascular disease (CVD) (i.e., symptomatic coronary artery disease or ischemic stroke) use a low- to moderate-dose statin for the prevention of CVD events and mortality when all of the following criteria are met: (1) they are ...

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2017/0115/od1.html

Statins for Primary Cardiovascular Prevention - Cochrane for Clinicians - American ...

Oct 1, 2011 - Trials to date have found that statins reduce all-cause mortality, composite cardiovascular outcomes, and revascularization. However, most trials included large numbers of persons with known CVD. Clear evidence of the effectiveness of statins to prevent a first cardiovascular event is ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2011/1001/p767.html

Statins in Persons at Low Risk of Cardiovascular Disease - Medicine by the Numbers - ...

Nov 1, 2017 - Despite the small reductions in nonfatal heart attacks and strokes, statins were not associated with a reduction in serious illness overall.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2017/1101/od1.html

Statins Ineffective for Primary Prevention of Cardiovascular Disease in Patients 75 ...

Apr 1, 2019 - In this retrospective study, statin treatment in patients 75 years or older without preexisting CVD did not change the likelihood of developing CVD or reduce any-cause mortality. However, patients 75 to 84 years of age with diabetes mellitus benefitted from treatment. These results ...

American Family Physician : POEMs

https://www.aafp.org/afp/2019/0401/p461.html

The JUPITER Study: Biomarkers Plus Statin vs. Lifestyle Modification for Preventing ...

Mar 15, 2009 - ...COLIN KOPES-KERR, MD, Santa Rosa Family Medicine Residency, Santa Rosa, California MARK EBELL, MD, MS, University of Georgia, Athens, Georgia Am Fam Physician. 2009 Mar 15;79(6):438-442. The JUPITER (Justification for the Use of Statins in Prevention: An Intervention Trial...

American Family Physician : Editorials

https://www.aafp.org/afp/2009/0315/p438.html

The Role of Nonstatin Therapy in Managing Hyperlipidemia - Editorials: Controversies in...

Nov 1, 2010 - When treating hyperlipidemia, physicians often face the question of the clinical value of nonstatin drugs, including bile acid sequestrants, fibrates (fibric acid derivatives), niacin, and cholesterol-absorption inhibitors. This editorial highlights the most prominent trial data and ...

American Family Physician : Editorials: Controversies in Family Medicine

https://www.aafp.org/afp/2010/1101/p1056.html

Treatment of Cholesterol Abnormalities - American Family Physician

Mar 15, 2005 - Cardiovascular disease and its subset coronary heart disease are leading causes of morbidity and mortality in the United States and worldwide. In general, higher levels of low-density lipoprotein cholesterol are associated with an increased risk of coronary heart disease, myocardial ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0315/p1137.html

U.S. Statin Guidelines: Expensive but Not Necessarily Effective - Editorials - American...

May 15, 2007 - ...HENRY C. BARRY, MD, MS, Michigan State University College of Human Medicine, East Lansing, Michigan JEROME R. HOFFMAN, MD, MA, David Geffen School of Medicine at the University of California at Los Angeles, Los Angeles, California Am Fam Physician. 2007 May 15;75(10):1453-1459....

American Family Physician : Editorials

https://www.aafp.org/afp/2007/0515/p1453.html

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