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stroke

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afp20191001p405.pdf

...Evidence-Based Answer Treatment of AFib with a factor Xa inhibi- tor results in a decrease in the combined end point of stroke and embolic events (odds ratio [OR] = 0.89; 95% CI, 0.82 to 0.97), as well as a decrease in intracranial hemorrhage (OR = 0.50; 95% CI, 0.42 to 0.59) and...

American Family Physician

https://www.aafp.org/afp/2019/1001/afp20191001p405.pdf

afp20191015p462.pdf

...fibrillation beneficial for reducing the risk of stroke? A limited number of trials that examined the risk of temporary interruption of anticoagula- tion before a variety of procedures did not find a reduction in the risk of stroke, but they did show an increased risk of bleeding...

American Family Physician

https://www.aafp.org/afp/2019/1015/afp20191015p462.pdf

afp20191015p463.pdf

...of randomized controlled trials [RCTs].) Dual antiplatelet therapy decreases the risk of myocardial infarction (MI) and isch- emic stroke (number needed to treat [NNT] = 77 and 43, respectively) with no change in mortal- ity. It also increases the risks of major and minor bleeding...

American Family Physician

https://www.aafp.org/afp/2019/1015/afp20191015p463.pdf

afp20191101od1.pdf

...heart attack, stroke Harm End Points: Major bleeding, dyspnea Narrative: Dual antiplatelet therapy (aspirin plus clopidogrel [Plavix] or ticagrelor [Brillinta]) com- pared with aspirin alone after PCI modestly reduces non- fatal events such as heart attack and stroke.1,2 This...

American Family Physician

https://www.aafp.org/afp/2019/1101/afp20191101od1.pdf

afp20191101p540.pdf

...= 100), and fewer strokes (NNT = 166) than those treated with RAS inhibitors. Patients treated with RAS inhibitors have fewer deaths and hospitalizations from heart failure than those treated with calcium channel blockers (CCBs; NNT = 83), although CCBs decrease stroke risk more...

American Family Physician

https://www.aafp.org/afp/2019/1101/afp20191101p540.pdf

afp20191101p541.pdf

...= 100), and fewer strokes (NNT = 166) than those treated with RAS inhibitors. Patients treated with RAS inhibitors have fewer deaths and hospitalizations from heart failure than those treated with calcium channel blockers (CCBs; NNT = 83), although CCBs decrease stroke risk more...

American Family Physician

https://www.aafp.org/afp/2019/1101/afp20191101p541.pdf

afp20191115p618.pdf

...Air pollution is associated with increased risks of coronary heart disease, myocardial infarction, and stroke, and is asso- ciated with increased emergency department visits, chronic obstructive pulmonary disease and asthma exacerbations, and development of respiratory disease....

American Family Physician

https://www.aafp.org/afp/2019/1115/afp20191115p618.pdf

afp20191115p649.pdf

...within 60 minutes of pre- sentation to avoid such adverse outcomes as con- gestive heart failure, myocardial ischemia, renal failure, and stroke. CONSENSUS AND EXPERT OPINION Epidural and spinal anesthesia are appropriate options during delivery for women who have a stable...

American Family Physician

https://www.aafp.org/afp/2019/1115/afp20191115p649.pdf

afp20191201p676.pdf

...cardiovascular mortality (studied in nine trials, with varying definitions, including coronary artery disease or ischemic heart disease plus stroke) between patients undergoing general health checks and those in control groups. Further data analysis demonstrated no difference...

American Family Physician

https://www.aafp.org/afp/2019/1201/afp20191201p676.pdf

afp20191201p677.pdf

...cardiovascular mortality (studied in nine trials, with varying definitions, including coronary artery disease or ischemic heart disease plus stroke) between patients undergoing general health checks and those in control groups. Further data analysis demonstrated no difference...

American Family Physician

https://www.aafp.org/afp/2019/1201/afp20191201p677.pdf

afp20191201p680.pdf

...Multiple sclerosis, Parkinson disease, spinal cord injury, stroke, trauma Impaired mobility and/or thermoregulation Peripheral neuropathy Impaired sensation Psychiatric Alcoholism Behavioral modifications; vasodilatory effects; malnutrition/depleted glycogen stores...

American Family Physician

https://www.aafp.org/afp/2019/1201/afp20191201p680.pdf

afp20191201p687.pdf

...Functional: neurogenic bladder, diabetes, multiple sclerosis, stroke, pharmacologic adverse effects (anticholinergics, antidepressants) Prostate: benign prostatic hypertrophy, carcinoma, infection Urethral: posterior urethral valves, strictures, trauma, infections,...

American Family Physician

https://www.aafp.org/afp/2019/1201/afp20191201p687.pdf

afp20191201p709.pdf

...2007, American Family Physician pub- lished the inaugural Close-ups department, featur- ing a story about my mother, who had experienced a stroke, and my father, who cared for her at home for seven years.1 Officially, their relationship lasted 56 years, but emotionally it never...

American Family Physician

https://www.aafp.org/afp/2019/1201/afp20191201p709.pdf

afp20191215od2.pdf

...monotherapy for up to five years. The primary end point was a composite of cardiovascular death, myocardial infarction, stent thrombosis, stroke, or bleeding. Individ- uals masked to treatment group assignment adjudicated all clinical events. Complete follow-up occurred for 98.8% of...

American Family Physician

https://www.aafp.org/afp/2019/1215/afp20191215od2.pdf

afp20191215od3.pdf

...monotherapy for up to five years. The primary end point was a composite of cardiovascular death, myocardial infarction, stent thrombosis, stroke, or bleeding. Individ- uals masked to treatment group assignment adjudicated all clinical events. Complete follow-up occurred for 98.8% of...

American Family Physician

https://www.aafp.org/afp/2019/1215/afp20191215od3.pdf

afp20191215od4.pdf

...monotherapy for up to five years. The primary end point was a composite of cardiovascular death, myocardial infarction, stent thrombosis, stroke, or bleeding. Individ- uals masked to treatment group assignment adjudicated all clinical events. Complete follow-up occurred for 98.8% of...

American Family Physician

https://www.aafp.org/afp/2019/1215/afp20191215od4.pdf

afp20191215od5.pdf

...monotherapy for up to five years. The primary end point was a composite of cardiovascular death, myocardial infarction, stent thrombosis, stroke, or bleeding. Individ- uals masked to treatment group assignment adjudicated all clinical events. Complete follow-up occurred for 98.8% of...

American Family Physician

https://www.aafp.org/afp/2019/1215/afp20191215od5.pdf

afp20191215p742.pdf

...current evidence is insufficient to assess the balance of benefits and harms of statins in people older than 75 years who have no history of stroke or heart attack.2 For people 65 to 75 years of age with one or more risk factors, the U.S. Preventive Services Task Force recommends...

American Family Physician

https://www.aafp.org/afp/2019/1215/afp20191215p742.pdf

afp20191215p751.pdf

...Any condition that may compromise the handling of respira- tory secretions (e.g., neuromuscular diseases, cerebral palsy, stroke, seizure disorder, dementia) Asthma or other chronic pulmonary disease Chronic kidney disease Chronic liver disease Heart disease (acquired or...

American Family Physician

https://www.aafp.org/afp/2019/1215/afp20191215p751.pdf

afp20200101p17.pdf

...prob- lems such as atrial fibrillation, congestive heart failure, coronary artery disease, depression, diabetes mellitus, hypertension, and stroke.3 CPAP is the current first-line therapy; however, up to two-thirds of patients do not adhere to treatment.4 Positional therapies for...

American Family Physician

https://www.aafp.org/afp/2020/0101/afp20200101p17.pdf

afp20200101p44.pdf

...771 participants with incident CHD and 4,254 without CHD) sampled from the REGARDS (Reasons for Geographic and Racial Differences in Stroke) trial.7,8 The abstract reports HRs for CHD using sex-specific cut-offs for elevated Lp-PLA2 activity (defined as greater than 80th...

American Family Physician

https://www.aafp.org/afp/2020/0101/afp20200101p44.pdf

afp20200101p5.pdf

...Initiate Stroke-Protective Therapy Original Article: Downsides of Detecting Atrial Fibrillation in Asymptomatic Patients [Editorials] Issue Date: March 15, 2019 See additional reader comments at: https://www.aafp.org/ afp/2019/0315/p354.html To the Editor: Stroke is...

American Family Physician

https://www.aafp.org/afp/2020/0101/afp20200101p5.pdf

afp20200101p6.pdf

...Initiate Stroke-Protective Therapy Original Article: Downsides of Detecting Atrial Fibrillation in Asymptomatic Patients [Editorials] Issue Date: March 15, 2019 See additional reader comments at: https://www.aafp.org/ afp/2019/0315/p354.html To the Editor: Stroke is...

American Family Physician

https://www.aafp.org/afp/2020/0101/afp20200101p6.pdf

afp20200101p7.pdf

...Initiate Stroke-Protective Therapy Original Article: Downsides of Detecting Atrial Fibrillation in Asymptomatic Patients [Editorials] Issue Date: March 15, 2019 See additional reader comments at: https://www.aafp.org/ afp/2019/0315/p354.html To the Editor: Stroke is...

American Family Physician

https://www.aafp.org/afp/2020/0101/afp20200101p7.pdf

afp20200115p123.pdf

...summary focuses on the new and revised rec- ommendations for choosing an anticoagu- lant and new recommendations for preventing stroke via nonpharmacologic options and use of catheter ablation. Key Recommendations HIGH-QUALITY EVIDENCE Based on high-quality evidence, oral...

American Family Physician

https://www.aafp.org/afp/2020/0115/afp20200115p123.pdf

afp20200115p95.pdf

...Upper motor neurons, which are located in the cerebral cortex, brainstem, and corticospinal tracts, may be injured from stroke, multiple scle- rosis, and spinal cord or brain masses. Lower motor neurons, which are located in the ante- rior horn of the spinal cord, nerve roots, and...

American Family Physician

https://www.aafp.org/afp/2020/0115/afp20200115p95.pdf

afp20200215p206.pdf

...anticoag- ulation therapy does not increase the risk of future diver- ticular bleeding and is associated with an increased risk of ischemic stroke when discontinued.14 Data Sources: Multiple searches were performed in Essential Evidence, PubMed, the Cochrane database, and Google...

American Family Physician

https://www.aafp.org/afp/2020/0215/afp20200215p206.pdf

afp20200215p213.pdf

...24. Tranchida GV, Van Heest A. Preferred options and evidence for upper limb surgery for spasticity in cerebral palsy, stroke, and brain injury [published online October 9, 2019]. J Hand Surg Eur. Accessed November 5, 2019. https:// journals.sagepub.co...

American Family Physician

https://www.aafp.org/afp/2020/0215/afp20200215p213.pdf

afp20200215p248.pdf

...hospitalizations for acute myocardial infarction, unstable angina, stroke, heart failure, or hypertension) at one year. Study design: Cohort (retrospective) Funding source: Government Allocation: Uncertain Setting: Inpatient (any location) with outpatient follow-up...

American Family Physician

https://www.aafp.org/afp/2020/0215/afp20200215p248.pdf

afp20200215p248a.pdf

...hospitalizations for acute myocardial infarction, unstable angina, stroke, heart failure, or hypertension) at one year. Study design: Cohort (retrospective) Funding source: Government Allocation: Uncertain Setting: Inpatient (any location) with outpatient follow-up...

American Family Physician

https://www.aafp.org/afp/2020/0215/afp20200215p248a.pdf

afp20200215p249.pdf

...hospitalizations for acute myocardial infarction, unstable angina, stroke, heart failure, or hypertension) at one year. Study design: Cohort (retrospective) Funding source: Government Allocation: Uncertain Setting: Inpatient (any location) with outpatient follow-up...

American Family Physician

https://www.aafp.org/afp/2020/0215/afp20200215p249.pdf

afp20200215p250.pdf

...hospitalizations for acute myocardial infarction, unstable angina, stroke, heart failure, or hypertension) at one year. Study design: Cohort (retrospective) Funding source: Government Allocation: Uncertain Setting: Inpatient (any location) with outpatient follow-up...

American Family Physician

https://www.aafp.org/afp/2020/0215/afp20200215p250.pdf

afp20200301p294.pdf

...per year.5 Because non-vitamin K oral anticoag- ulants show similar or better stroke prevention than warfarin with a reduction in major bleed- ing, they are now recommended more than war- farin.12 A 2017 systematic review of 23 RCTs that included 94,656 individuals showed that apix-...

American Family Physician

https://www.aafp.org/afp/2020/0301/afp20200301p294.pdf

afp20200301p309.pdf

...This study found that linagliptin is noninferior to glimepir­ ide for reducing the risk of cardiovascular death, myocardial infarction, and stroke in adults with type 2 diabetes at an increased risk of cardiovascular disease. Although hypogly­ cemic events occurred significantly...

American Family Physician

https://www.aafp.org/afp/2020/0301/afp20200301p309.pdf

afp20200301p310.pdf

...This study found that linagliptin is noninferior to glimepir­ ide for reducing the risk of cardiovascular death, myocardial infarction, and stroke in adults with type 2 diabetes at an increased risk of cardiovascular disease. Although hypogly­ cemic events occurred significantly...

American Family Physician

https://www.aafp.org/afp/2020/0301/afp20200301p310.pdf

afp20200301p310a.pdf

...This study found that linagliptin is noninferior to glimepir­ ide for reducing the risk of cardiovascular death, myocardial infarction, and stroke in adults with type 2 diabetes at an increased risk of cardiovascular disease. Although hypogly­ cemic events occurred significantly...

American Family Physician

https://www.aafp.org/afp/2020/0301/afp20200301p310a.pdf

afp20200315od1.pdf

...These harms include vasomotor symptoms, gastrointestinal symptoms, musculoskeletal pain, and possible cardiovas- cular events, such as stroke. Aromatase inhibitors do not reduce, and may even increase, risk of fractures. USPSTF ASSESSMENT The USPSTF concludes with moderate...

American Family Physician

https://www.aafp.org/afp/2020/0315/afp20200315od1.pdf

afp20200315p341.pdf

...- - Adults with history of stroke, 18 to 65 years of age ≥ 140/90 120 to 130/70 to 79 Adults with his- tory of stroke§ ≥ 130/80 Adults with history of stroke, 65 to 79 years of age ≥ 140/90 130 to 139/70 to 79 Adults with history of stroke, 80 years and older ≥...

American Family Physician

https://www.aafp.org/afp/2020/0315/afp20200315p341.pdf

afp20200401p409.pdf

...heart failure, or acute lung injury. Additional modalities can be used to determine fluid tolerance and fluid responsiveness (increase in stroke volume) for assessment of optimal fluid management. These include ultrasonography to assess infe- rior vena cava collapsibility or...

American Family Physician

https://www.aafp.org/afp/2020/0401/afp20200401p409.pdf

afp20200401p434.pdf

...assessed outcomes, includ- ing the primary composite outcome of myocardial infarc- tion, coronary revascularization, heart failure, stroke, and cardiovascular disease death. Complete follow-up occurred for more than 99% of participants at a median of 6.3 years. Using...

American Family Physician

https://www.aafp.org/afp/2020/0401/afp20200401p434.pdf

afp20200401p435.pdf

...assessed outcomes, includ- ing the primary composite outcome of myocardial infarc- tion, coronary revascularization, heart failure, stroke, and cardiovascular disease death. Complete follow-up occurred for more than 99% of participants at a median of 6.3 years. Using...

American Family Physician

https://www.aafp.org/afp/2020/0401/afp20200401p435.pdf

afp20200401p435a.pdf

...assessed outcomes, includ- ing the primary composite outcome of myocardial infarc- tion, coronary revascularization, heart failure, stroke, and cardiovascular disease death. Complete follow-up occurred for more than 99% of participants at a median of 6.3 years. Using...

American Family Physician

https://www.aafp.org/afp/2020/0401/afp20200401p435a.pdf

afp20200501od2.pdf

...tranexamic acid and placebo in the rate of thromboembolic events (deep venous thrombosis, pulmonary embolism, myocardial infarction, and stroke), organ failure (renal, cardiac, respiratory), or sepsis and use of uterotonics. A systematic review and meta-analysis,5 which only...

American Family Physician

https://www.aafp.org/afp/2020/0501/afp20200501od2.pdf

afp20200501p542.pdf

...Commit- tees of the Council on Clinical Cardiology; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular and Stroke Nursing; Council on Quality of Care and Outcomes Research. Drugs that may cause or exacerbate heart failure: a scientific statement from the...

American Family Physician

https://www.aafp.org/afp/2020/0501/afp20200501p542.pdf

afp20200515p608.pdf

...at bedtime had a lower likelihood of the composite outcome of myo- cardial infarction (MI), coronary revascularization, heart failure, stroke, or cardiovascular death (hazard ratio = 0.55; 95% CI, 0.50 to 0.61; number needed to treat to prevent one event over 6.3 years = 20)....

American Family Physician

https://www.aafp.org/afp/2020/0515/afp20200515p608.pdf

afp20200515p618.pdf

...adverse effects appear to be similar to those of other combined hormonal contraceptives and include thrombosis, myocar- dial infarction, stroke, carcinoma, gallbladder disease, liver disease, dyslipidemia, and hyper- tension.1,2 Because segesterone acetate is a new progesterone,...

American Family Physician

https://www.aafp.org/afp/2020/0515/afp20200515p618.pdf

afp20200515p625.pdf

...Chronic medical conditions, such as diabetes mellitus, heart disease, or stroke, are more prevalent as people age and may affect driving ability. Medications used to treat chronic and aging-related conditions may impair optimal functioning and exacerbate driving-related hazards....

American Family Physician

https://www.aafp.org/afp/2020/0515/afp20200515p625.pdf

afp20200601p648.pdf

...Decompression Surgery, Fabric Masks, Heat Stroke, e-Cigarette Use Is decompression surgery effective for shoulder impingement syndrome? Decompression surgery is no more effective than exercise for shoulder impingement syndrome and has the same results as no surgery accord- ing to...

American Family Physician

https://www.aafp.org/afp/2020/0601/afp20200601p648.pdf

afp20200601p692.pdf

...Increased risk of heat stroke or exhaustion Peripheral nerve entrapments Pressure ulcers 694 American Family Physician www.aafp.org/afp epub ◆ Date xx, xxxx

American Family Physician

https://www.aafp.org/afp/2020/0601/afp20200601p692.pdf

afp20200601p695.pdf

...age of participants was 65 years, 25% had diabetes mellitus, 33% had a previous myo- cardial infarction, and 9% had a previous stroke or transient ischemic attack. Left main disease was present in 40% and three-vessel disease in 60% of the patients. The primary outcome was all-cause...

American Family Physician

https://www.aafp.org/afp/2020/0601/afp20200601p695.pdf

afp20200601p695a.pdf

...age of participants was 65 years, 25% had diabetes mellitus, 33% had a previous myo- cardial infarction, and 9% had a previous stroke or transient ischemic attack. Left main disease was present in 40% and three-vessel disease in 60% of the patients. The primary outcome was all-cause...

American Family Physician

https://www.aafp.org/afp/2020/0601/afp20200601p695a.pdf

afp20200601p696.pdf

...age of participants was 65 years, 25% had diabetes mellitus, 33% had a previous myo- cardial infarction, and 9% had a previous stroke or transient ischemic attack. Left main disease was present in 40% and three-vessel disease in 60% of the patients. The primary outcome was all-cause...

American Family Physician

https://www.aafp.org/afp/2020/0601/afp20200601p696.pdf

afp20200601p698.pdf

...age of participants was 65 years, 25% had diabetes mellitus, 33% had a previous myo- cardial infarction, and 9% had a previous stroke or transient ischemic attack. Left main disease was present in 40% and three-vessel disease in 60% of the patients. The primary outcome was all-cause...

American Family Physician

https://www.aafp.org/afp/2020/0601/afp20200601p698.pdf

afp20200615od1.pdf

...9. Holsinger T, Deveau J, Boustani M, et al. Does this patient have demen- tia? JAMA. 2007; 297(21): 2391-2404. 10. Plassman BL, Williams JW Jr, Burke JR, et al. Systematic review: factors associated with risk for and possible prevention of cognitive decline in later life. Ann...

American Family Physician

https://www.aafp.org/afp/2020/0615/afp20200615od1.pdf

afp20200615p748.pdf

...but no stenosis or significant regurgitation. A cardiologist recommended pre- scribing a direct oral anticoagulant to prevent an embolic stroke. However, Mr. H’s primary care physician is con- cerned about the risks of anticoagulation because of recent functional decline in the...

American Family Physician

https://www.aafp.org/afp/2020/0615/afp20200615p748.pdf

afp20200615p753.pdf

... D. Mild cognitive impairment and demen- tia interfere with independent daily functioning.  E. Dementia currently affects an esti- mated 8 to 9 million people in the United States. Answers 1. The correct answer is D. The USPSTF found insufficient evidence to assess the...

American Family Physician

https://www.aafp.org/afp/2020/0615/afp20200615p753.pdf

afp20200701p30.pdf

...blood cells for arbitrary hemoglobin or hematocrit thresholds and in the absence of symptoms or active coronary disease, heart failure, or stroke. Society of Hospital Medicine (Adult) Do not transfuse red blood cells in hemodynamically stable, nonbleeding patients in the...

American Family Physician

https://www.aafp.org/afp/2020/0701/afp20200701p30.pdf

afp20200715p115.pdf

...no difference in the rate of major adverse cardiovascular events (i.e., cardiovascular-related death, myocardial infarc- tion, or ischemic stroke) between patients taking dapagliflozin and placebo, trial investigators con- sider the reduction in combined renal outcome as...

American Family Physician

https://www.aafp.org/afp/2020/0715/afp20200715p115.pdf

afp20200801p150.pdf

...Ripping or tearing sensation in neck, diplopia, drop attacks, headache, syncope, transient ischemic attack symptoms, vertigo, vision changes Kernig sign, unilateral decrease in sensation, unilat- eral weakness Urgent referral and imaging (CT or CT angiography) CRP =...

American Family Physician

https://www.aafp.org/afp/2020/0801/afp20200801p150.pdf

afp20200815p247.pdf

...Reduction in Cardiovascular Outcome After Ischemic Stroke with Lower LDL Target, but also Harms; No Change in All-Cause Mortality Clinical Question Does a lower low-density lipoprotein (LDL) tar- get following ischemic stroke reduce the likeli- hood of major adverse...

American Family Physician

https://www.aafp.org/afp/2020/0815/afp20200815p247.pdf

afp20200815p248.pdf

...Reduction in Cardiovascular Outcome After Ischemic Stroke with Lower LDL Target, but also Harms; No Change in All-Cause Mortality Clinical Question Does a lower low-density lipoprotein (LDL) tar- get following ischemic stroke reduce the likeli- hood of major adverse...

American Family Physician

https://www.aafp.org/afp/2020/0815/afp20200815p248.pdf

afp20200815p248a.pdf

...Reduction in Cardiovascular Outcome After Ischemic Stroke with Lower LDL Target, but also Harms; No Change in All-Cause Mortality Clinical Question Does a lower low-density lipoprotein (LDL) tar- get following ischemic stroke reduce the likeli- hood of major adverse...

American Family Physician

https://www.aafp.org/afp/2020/0815/afp20200815p248a.pdf

afp20200901p271.pdf

...Effectiveness of PPAR Gamma Agonists in Preventing Recurrent Stroke and Other Vascular Events Madhavi Singh, MD; Kristen Grine, DO; and Amy Hays, MD, Penn State University College of Medicine, Hershey, Pennsylvania Author disclosure: No relevant financial affiliations....

American Family Physician

https://www.aafp.org/afp/2020/0901/afp20200901p271.pdf

afp20200915p332.pdf

...for dual antiplatelet therapy after stroke or transient ischemic attack? A 10- to 21-day course of dual antiplatelet ther- apy reduces stroke recurrence and improves quality of life after mild stroke or high-risk transient ischemic attack. Low-dose aspirin and a 300-mg loading dose...

American Family Physician

https://www.aafp.org/afp/2020/0915/afp20200915p332.pdf

afp20200915p335.pdf

...and muscle relax- ants.7 The use of nonopioid medications is often restricted by limited effectiveness or adverse effects, such as bleeding, strokes, and cardiovascular and renal disease with NSAIDs.8 Adjuvant medications such as gabapentin (Neurontin) have been used for nonapproved...

American Family Physician

https://www.aafp.org/afp/2020/0915/afp20200915p335.pdf

afp20201015od4.pdf

...age, sex, education), smoking status, alcohol intake, and diagnoses of chronic medical conditions (e.g., diabetes mellitus, heart disease, stroke, cancer, chronic bronchitis). In addition to count- ing steps, step intensity was estimated based on extended bouts of stepping and peak...

American Family Physician

https://www.aafp.org/afp/2020/1015/afp20201015od4.pdf

afp20201015od5.pdf

...age, sex, education), smoking status, alcohol intake, and diagnoses of chronic medical conditions (e.g., diabetes mellitus, heart disease, stroke, cancer, chronic bronchitis). In addition to count- ing steps, step intensity was estimated based on extended bouts of stepping and peak...

American Family Physician

https://www.aafp.org/afp/2020/1015/afp20201015od5.pdf

afp20201015od6.pdf

...age, sex, education), smoking status, alcohol intake, and diagnoses of chronic medical conditions (e.g., diabetes mellitus, heart disease, stroke, cancer, chronic bronchitis). In addition to count- ing steps, step intensity was estimated based on extended bouts of stepping and peak...

American Family Physician

https://www.aafp.org/afp/2020/1015/afp20201015od6.pdf

afp20201015p478.pdf

...• Acute complications of COVID-19 include pneumonia, acute respiratory distress syndrome, stroke, and arterial and venous thrombosis. Hospitalized patients may have debil- ity 70 and mental health effects.71 Factors that may increase the risk of these complications include: ◦ A diet...

American Family Physician

https://www.aafp.org/afp/2020/1015/afp20201015p478.pdf

afp20201101p530.pdf

...were all-cause mortality, incidence of type 2 diabetes, serious adverse effects, cardiovascular mortality, nonfatal myocardial infarction or stroke, health- related quality of life, and socioeconomic effects. Patients who used metformin for one to five years were less likely to...

American Family Physician

https://www.aafp.org/afp/2020/1101/afp20201101p530.pdf

afp20201101p531.pdf

...were all-cause mortality, incidence of type 2 diabetes, serious adverse effects, cardiovascular mortality, nonfatal myocardial infarction or stroke, health- related quality of life, and socioeconomic effects. Patients who used metformin for one to five years were less likely to...

American Family Physician

https://www.aafp.org/afp/2020/1101/afp20201101p531.pdf

afp20201101p539.pdf

...each condition and be able to perform a basic eye examination. Patients with a central retinal artery occlusion require urgent referral for stroke eval- uation and should receive therapy to lower intraocular pressure and vasodilating agents to minimize retinal ischemia. Chemical...

American Family Physician

https://www.aafp.org/afp/2020/1101/afp20201101p539.pdf

afp20201101p562.pdf

...current evidence is insufficient to assess the balance of benefits and harms of ECG screening for AF because of a lack of information on stroke risk and benefit of anticoagulation in asymptomatic patients with screening-detected AF (as opposed to clinically detected).6,7 There are...

American Family Physician

https://www.aafp.org/afp/2020/1101/afp20201101p562.pdf

afp20201115p592.pdf

...heart disease, ADHD medications do not increase the risk of serious cardiovascular events including sudden death, myocardial infarction, and stroke.45 Electrocardiog- raphy or cardiology referral is recommended only if there are concerning symptoms or family history.2,17,27,45...

American Family Physician

https://www.aafp.org/afp/2020/1115/afp20201115p592.pdf

afp20201115p603.pdf

...P < .001).6 However, some studies have shown an association between vitamin E and an increased risk of prostate cancer and hemorrhagic stroke; one study demonstrated a reduction in thrombotic TABLE 5 Noninvasive Tests Helpful in Assessing the Likelihood of Hepatic Fibrosis...

American Family Physician

https://www.aafp.org/afp/2020/1115/afp20201115p603.pdf

afp20201115p627.pdf

...reluctant to start or add injectable treatment and for whom weight loss is desired. It does not increase major CV events (including nonfatal stroke or nonfatal myocardial infarc- tion) in higher-risk patients. The cost and hyperglycemia- lowering benefits of oral semaglutide are...

American Family Physician

https://www.aafp.org/afp/2020/1115/afp20201115p627.pdf

afp20201201p645a.pdf

...commonly headache, anosmia, and ageusia-in addition to the more well-recognized respiratory findings. Other manifestations include stroke, impairment of consciousness, coma, seizure, and encephalopathy.1 An early case series from Wuhan, China, identified neurologic features in 78 of...

American Family Physician

https://www.aafp.org/afp/2020/1201/afp20201201p645a.pdf

afp20201201p673.pdf

...in the likelihood of cancer or in the composite cardiovascular outcome (cardiovascular death, nonfatal myocardial infarc- tion, or ischemic stroke). In 2019, another POEM reported on the ASCEND (A Study of Cardiovascular Events in Dia- betes) trial of the use of omega-3 fatty acids...

American Family Physician

https://www.aafp.org/afp/2020/1201/afp20201201p673.pdf

afp20201201p679.pdf

...in the basal ganglia, particularly in the substan- tia nigra,2 and development of Lewy bodies in the dopaminergic neurons. Lewy bodies are the pathologic feature of Parkinson disease.3 How- ever, Lewy bodies are nonspecific for Parkinson disease and are found in multiple...

American Family Physician

https://www.aafp.org/afp/2020/1201/afp20201201p679.pdf

afp20201215p716.pdf

...serious post-COVID complications from those with less concerning symptoms. Serious complications include pulmonary embolus, heart failure, stroke, myocardial infarction, lung fibrosis, neurologic derangement, and severe deterioration in men- tal health. Patients presenting with...

American Family Physician

https://www.aafp.org/afp/2020/1215/afp20201215p716.pdf

afp20201215p740.pdf

...Brissaud reflex Stroking the sole of the foot results in a vigorous contraction of the ipsilat- eral tensor fasciae lata Not reported Lhermitte sign Flexion of the neck results in a shoot- ing, electrical sensation down the spine Not reported Information from references...

American Family Physician

https://www.aafp.org/afp/2020/1215/afp20201215p740.pdf

afp20201215p753.pdf

...for mild cognitive impairment or dementia; therefore, clinicians who have a high index of suspicion should use a screening tool for demen- tia such as the Mini-Cog (https:// mini-cog.com). Patients with dementia who are hospitalized are at high risk of iatrogenic harms, including...

American Family Physician

https://www.aafp.org/afp/2020/1215/afp20201215p753.pdf

afp20210101p42.pdf

...guide specific diagnostic imaging choices. Noncontrast head computed tomography is the first-line modality when a stroke is suspected. Magnetic resonance imaging stroke protocols and computed tomography perfusion scans can augment evaluation and poten- tially expand pharmacologic...

American Family Physician

https://www.aafp.org/afp/2021/0101/afp20210101p42.pdf

afp20210115od2.pdf

...women in the same age group with a previous hysterectomy. The original trials were stopped after 7.2 years because of an increased risk of stroke in the treatment groups. After the original trials were stopped, less than 4% of the women reported continuing hormone therapy. The...

American Family Physician

https://www.aafp.org/afp/2021/0115/afp20210115od2.pdf

afp20210115od3.pdf

...women in the same age group with a previous hysterectomy. The original trials were stopped after 7.2 years because of an increased risk of stroke in the treatment groups. After the original trials were stopped, less than 4% of the women reported continuing hormone therapy. The...

American Family Physician

https://www.aafp.org/afp/2021/0115/afp20210115od3.pdf

afp20210115od4.pdf

...women in the same age group with a previous hysterectomy. The original trials were stopped after 7.2 years because of an increased risk of stroke in the treatment groups. After the original trials were stopped, less than 4% of the women reported continuing hormone therapy. The...

American Family Physician

https://www.aafp.org/afp/2021/0115/afp20210115od4.pdf

afp20210115p117.pdf

...Icosapent Ethyl (Vascepa) for Hyperlipidemia/Hypercholesterolemia to Reduce Risk of Heart Attack and Stroke Leena Myran, PharmD, BCPS, and Thanh-Nga Nguyen, PharmD, MBA, BCACP University of Wyoming Family Medicine Residency Program, Cheyenne, Wyoming Icosapent ethyl (Vascepa)...

American Family Physician

https://www.aafp.org/afp/2021/0115/afp20210115p117.pdf

afp20210115p97.pdf

...Oropharyngeal Pathology Oropharyngeal dysphagia is most commonly related to chronic neurologic conditions, particularly Parkinson dis- ease, stroke, and dementia; it is not part of normal aging.5 Dysphagia: Evaluation and Collaborative Management John M. Wilkinson, MD; Don...

American Family Physician

https://www.aafp.org/afp/2021/0115/afp20210115p97.pdf

afp20210201p155.pdf

...medications, and even fewer benefit. Other limitations include serious adverse events, illustrated by a 20% to 30% rate of heart attack, stroke, or peripheral vascular events among patients taking ponatinib, which is used in treating chronic myelogenous leukemia. Immune checkpoint...

American Family Physician

https://www.aafp.org/afp/2021/0201/afp20210201p155.pdf

afp20210201p183.pdf

...In the United States, 5.8 million people 65 years and older (11.4% of this age group) are estimated to have clinical ATD.2,3 Deaths from stroke and heart disease have decreased over the past two decades while the number of deaths asso- ciated with clinical ATD has increased,...

American Family Physician

https://www.aafp.org/afp/2021/0201/afp20210201p183.pdf

afp20210215p219.pdf

...the number of health deficits and presence of multiple comorbidities.2 Patients diag- nosed with diabetes mellitus, respiratory disease, stroke, dementia, multiple sclerosis, connective tissue disease, osteoarthritis, and chronic fatigue syndrome have higher documented frailty...

American Family Physician

https://www.aafp.org/afp/2021/0215/afp20210215p219.pdf

afp20210215p227.pdf

...Neurologic disease: complex partial seizures, Huntington chorea, migraine headache, multiple sclerosis, neoplasm, stroke, traumatic brain injury, Wilson disease Vitamin deficiency: B12, folate, niacin, thiamine Medications Cardiovascular: captopril, hydralazine...

American Family Physician

https://www.aafp.org/afp/2021/0215/afp20210215p227.pdf

afp20210215p247a.pdf

...Fewer Subsequent Strokes with Ticagrelor Plus Aspirin than with Aspirin Alone Clinical Question Is ticagrelor (Brilinta) plus aspirin superior to aspirin alone for decreasing the risk of subse- quent stroke or death in patients with acute isch- emic stroke? Bottom Line For...

American Family Physician

https://www.aafp.org/afp/2021/0215/afp20210215p247a.pdf

afp20210215p248.pdf

...Fewer Subsequent Strokes with Ticagrelor Plus Aspirin than with Aspirin Alone Clinical Question Is ticagrelor (Brilinta) plus aspirin superior to aspirin alone for decreasing the risk of subse- quent stroke or death in patients with acute isch- emic stroke? Bottom Line For...

American Family Physician

https://www.aafp.org/afp/2021/0215/afp20210215p248.pdf

afp20210215p249.pdf

...Fewer Subsequent Strokes with Ticagrelor Plus Aspirin than with Aspirin Alone Clinical Question Is ticagrelor (Brilinta) plus aspirin superior to aspirin alone for decreasing the risk of subse- quent stroke or death in patients with acute isch- emic stroke? Bottom Line For...

American Family Physician

https://www.aafp.org/afp/2021/0215/afp20210215p249.pdf

afp20210215p252.pdf

...and nausea and vomiting can also occur with heat exhaustion. Severe EAH presents with men- tal status changes similar to exertional heat stroke. High ambient temperatures increase the risk of EAH as well as heat illness. Injury logs from a national park showed that one in five...

American Family Physician

https://www.aafp.org/afp/2021/0215/afp20210215p252.pdf

afp20210301od1.pdf

...Stroke or TIA Brit Long, MD, and Michael Gottlieb, MD Details for This Review Study Population: Five randomized controlled trials including a total of 10,739 patients with atherothrombotic ischemic stroke or transient ischemic attack (TIA) Efficacy End Points: Stroke...

American Family Physician

https://www.aafp.org/afp/2021/0301/afp20210301od1.pdf

afp20210301p311.pdf

...for Stroke Prevention in Older Patients with Atrial Fibrillation Clinical Question Is low-dose edoxaban (Savaysa) safe and effective for stroke prevention in older patients with atrial fibrillation? Bottom Line A lower dose of edoxaban is effective in decreasing stroke and...

American Family Physician

https://www.aafp.org/afp/2021/0301/afp20210301p311.pdf

afp20210301p312a.pdf

...for Stroke Prevention in Older Patients with Atrial Fibrillation Clinical Question Is low-dose edoxaban (Savaysa) safe and effective for stroke prevention in older patients with atrial fibrillation? Bottom Line A lower dose of edoxaban is effective in decreasing stroke and...

American Family Physician

https://www.aafp.org/afp/2021/0301/afp20210301p312a.pdf

afp20210315p366.pdf

...There is adequate evidence that counseling interventions reduce overall CVD events (e.g., myocardial infarction and stroke). There is convincing evidence that counseling interventions improve blood pressure, lipid and fasting blood glucose levels, and body weight/adiposity....

American Family Physician

https://www.aafp.org/afp/2021/0315/afp20210315p366.pdf

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