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stroke

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afp20200101p44.pdf

...771 participants with incident CHD and 4,254 without CHD) sampled from the REGARDS (Reasons for Geographic and Racial Differences in Stroke) trial.7,8 The abstract reports HRs for CHD using sex-specific cut-offs for elevated Lp-PLA2 activity (defined as greater than 80th...

American Family Physician

https://www.aafp.org/afp/2020/0101/afp20200101p44.pdf

afp20200101p5.pdf

...Initiate Stroke-Protective Therapy Original Article: Downsides of Detecting Atrial Fibrillation in Asymptomatic Patients [Editorials] Issue Date: March 15, 2019 See additional reader comments at: https://www.aafp.org/ afp/2019/0315/p354.html To the Editor: Stroke is...

American Family Physician

https://www.aafp.org/afp/2020/0101/afp20200101p5.pdf

afp20200101p6.pdf

...Initiate Stroke-Protective Therapy Original Article: Downsides of Detecting Atrial Fibrillation in Asymptomatic Patients [Editorials] Issue Date: March 15, 2019 See additional reader comments at: https://www.aafp.org/ afp/2019/0315/p354.html To the Editor: Stroke is...

American Family Physician

https://www.aafp.org/afp/2020/0101/afp20200101p6.pdf

afp20200101p7.pdf

...Initiate Stroke-Protective Therapy Original Article: Downsides of Detecting Atrial Fibrillation in Asymptomatic Patients [Editorials] Issue Date: March 15, 2019 See additional reader comments at: https://www.aafp.org/ afp/2019/0315/p354.html To the Editor: Stroke is...

American Family Physician

https://www.aafp.org/afp/2020/0101/afp20200101p7.pdf

afp20200115p123.pdf

...summary focuses on the new and revised rec- ommendations for choosing an anticoagu- lant and new recommendations for preventing stroke via nonpharmacologic options and use of catheter ablation. Key Recommendations HIGH-QUALITY EVIDENCE Based on high-quality evidence, oral...

American Family Physician

https://www.aafp.org/afp/2020/0115/afp20200115p123.pdf

afp20200115p95.pdf

...Upper motor neurons, which are located in the cerebral cortex, brainstem, and corticospinal tracts, may be injured from stroke, multiple scle- rosis, and spinal cord or brain masses. Lower motor neurons, which are located in the ante- rior horn of the spinal cord, nerve roots, and...

American Family Physician

https://www.aafp.org/afp/2020/0115/afp20200115p95.pdf

afp20200215p206.pdf

...anticoag- ulation therapy does not increase the risk of future diver- ticular bleeding and is associated with an increased risk of ischemic stroke when discontinued.14 Data Sources: Multiple searches were performed in Essential Evidence, PubMed, the Cochrane database, and Google...

American Family Physician

https://www.aafp.org/afp/2020/0215/afp20200215p206.pdf

afp20200215p248.pdf

...hospitalizations for acute myocardial infarction, unstable angina, stroke, heart failure, or hypertension) at one year. Study design: Cohort (retrospective) Funding source: Government Allocation: Uncertain Setting: Inpatient (any location) with outpatient follow-up...

American Family Physician

https://www.aafp.org/afp/2020/0215/afp20200215p248.pdf

afp20200215p248a.pdf

...hospitalizations for acute myocardial infarction, unstable angina, stroke, heart failure, or hypertension) at one year. Study design: Cohort (retrospective) Funding source: Government Allocation: Uncertain Setting: Inpatient (any location) with outpatient follow-up...

American Family Physician

https://www.aafp.org/afp/2020/0215/afp20200215p248a.pdf

afp20200215p249.pdf

...hospitalizations for acute myocardial infarction, unstable angina, stroke, heart failure, or hypertension) at one year. Study design: Cohort (retrospective) Funding source: Government Allocation: Uncertain Setting: Inpatient (any location) with outpatient follow-up...

American Family Physician

https://www.aafp.org/afp/2020/0215/afp20200215p249.pdf

afp20200215p250.pdf

...hospitalizations for acute myocardial infarction, unstable angina, stroke, heart failure, or hypertension) at one year. Study design: Cohort (retrospective) Funding source: Government Allocation: Uncertain Setting: Inpatient (any location) with outpatient follow-up...

American Family Physician

https://www.aafp.org/afp/2020/0215/afp20200215p250.pdf

afp20200301p294.pdf

...per year.5 Because non-vitamin K oral anticoag- ulants show similar or better stroke prevention than warfarin with a reduction in major bleed- ing, they are now recommended more than war- farin.12 A 2017 systematic review of 23 RCTs that included 94,656 individuals showed that apix-...

American Family Physician

https://www.aafp.org/afp/2020/0301/afp20200301p294.pdf

afp20200301p309a.pdf

...This study found that linagliptin is noninferior to glimepir­ ide for reducing the risk of cardiovascular death, myocardial infarction, and stroke in adults with type 2 diabetes at an increased risk of cardiovascular disease. Although hypogly­ cemic events occurred significantly...

American Family Physician

https://www.aafp.org/afp/2020/0301/afp20200301p309a.pdf

afp20200301p310.pdf

...This study found that linagliptin is noninferior to glimepir­ ide for reducing the risk of cardiovascular death, myocardial infarction, and stroke in adults with type 2 diabetes at an increased risk of cardiovascular disease. Although hypogly­ cemic events occurred significantly...

American Family Physician

https://www.aafp.org/afp/2020/0301/afp20200301p310.pdf

afp20200301p310a.pdf

...This study found that linagliptin is noninferior to glimepir­ ide for reducing the risk of cardiovascular death, myocardial infarction, and stroke in adults with type 2 diabetes at an increased risk of cardiovascular disease. Although hypogly­ cemic events occurred significantly...

American Family Physician

https://www.aafp.org/afp/2020/0301/afp20200301p310a.pdf

afp20200315od1.pdf

...These harms include vasomotor symptoms, gastrointestinal symptoms, musculoskeletal pain, and possible cardiovas- cular events, such as stroke. Aromatase inhibitors do not reduce, and may even increase, risk of fractures. USPSTF ASSESSMENT The USPSTF concludes with moderate...

American Family Physician

https://www.aafp.org/afp/2020/0315/afp20200315od1.pdf

afp20200315p341.pdf

...- - Adults with history of stroke, 18 to 65 years of age ≥ 140/90 120 to 130/70 to 79 Adults with his- tory of stroke§ ≥ 130/80 Adults with history of stroke, 65 to 79 years of age ≥ 140/90 130 to 139/70 to 79 Adults with history of stroke, 80 years and older ≥...

American Family Physician

https://www.aafp.org/afp/2020/0315/afp20200315p341.pdf

afp20200401p409.pdf

...heart failure, or acute lung injury. Additional modalities can be used to determine fluid tolerance and fluid responsiveness (increase in stroke volume) for assessment of optimal fluid management. These include ultrasonography to assess infe- rior vena cava collapsibility or...

American Family Physician

https://www.aafp.org/afp/2020/0401/afp20200401p409.pdf

afp20200401p434.pdf

...assessed outcomes, includ- ing the primary composite outcome of myocardial infarc- tion, coronary revascularization, heart failure, stroke, and cardiovascular disease death. Complete follow-up occurred for more than 99% of participants at a median of 6.3 years. Using...

American Family Physician

https://www.aafp.org/afp/2020/0401/afp20200401p434.pdf

afp20200401p434a.pdf

...assessed outcomes, includ- ing the primary composite outcome of myocardial infarc- tion, coronary revascularization, heart failure, stroke, and cardiovascular disease death. Complete follow-up occurred for more than 99% of participants at a median of 6.3 years. Using...

American Family Physician

https://www.aafp.org/afp/2020/0401/afp20200401p434a.pdf

afp20200401p435.pdf

...assessed outcomes, includ- ing the primary composite outcome of myocardial infarc- tion, coronary revascularization, heart failure, stroke, and cardiovascular disease death. Complete follow-up occurred for more than 99% of participants at a median of 6.3 years. Using...

American Family Physician

https://www.aafp.org/afp/2020/0401/afp20200401p435.pdf

afp20200501od2.pdf

...tranexamic acid and placebo in the rate of thromboembolic events (deep venous thrombosis, pulmonary embolism, myocardial infarction, and stroke), organ failure (renal, cardiac, respiratory), or sepsis and use of uterotonics. A systematic review and meta-analysis,5 which only...

American Family Physician

https://www.aafp.org/afp/2020/0501/afp20200501od2.pdf

afp20200501p542.pdf

...Commit- tees of the Council on Clinical Cardiology; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular and Stroke Nursing; Council on Quality of Care and Outcomes Research. Drugs that may cause or exacerbate heart failure: a scientific statement from the...

American Family Physician

https://www.aafp.org/afp/2020/0501/afp20200501p542.pdf

afp20200515p608.pdf

...at bedtime had a lower likelihood of the composite outcome of myo- cardial infarction (MI), coronary revascularization, heart failure, stroke, or cardiovascular death (hazard ratio = 0.55; 95% CI, 0.50 to 0.61; number needed to treat to prevent one event over 6.3 years = 20)....

American Family Physician

https://www.aafp.org/afp/2020/0515/afp20200515p608.pdf

afp20200515p618.pdf

...adverse effects appear to be similar to those of other combined hormonal contraceptives and include thrombosis, myocar- dial infarction, stroke, carcinoma, gallbladder disease, liver disease, dyslipidemia, and hyper- tension.1,2 Because segesterone acetate is a new progesterone,...

American Family Physician

https://www.aafp.org/afp/2020/0515/afp20200515p618.pdf

afp20200515p625.pdf

...Chronic medical conditions, such as diabetes mellitus, heart disease, or stroke, are more prevalent as people age and may affect driving ability. Medications used to treat chronic and aging-related conditions may impair optimal functioning and exacerbate driving-related hazards....

American Family Physician

https://www.aafp.org/afp/2020/0515/afp20200515p625.pdf

afp20200601p692.pdf

...Increased risk of heat stroke or exhaustion Peripheral nerve entrapments Pressure ulcers 694 American Family Physician www.aafp.org/afp epub ◆ Date xx, xxxx

American Family Physician

https://www.aafp.org/afp/2020/0601/afp20200601p692.pdf

afp20200601p695.pdf

...age of participants was 65 years, 25% had diabetes mellitus, 33% had a previous myo- cardial infarction, and 9% had a previous stroke or transient ischemic attack. Left main disease was present in 40% and three-vessel disease in 60% of the patients. The primary outcome was all-cause...

American Family Physician

https://www.aafp.org/afp/2020/0601/afp20200601p695.pdf

afp20200601p695a.pdf

...age of participants was 65 years, 25% had diabetes mellitus, 33% had a previous myo- cardial infarction, and 9% had a previous stroke or transient ischemic attack. Left main disease was present in 40% and three-vessel disease in 60% of the patients. The primary outcome was all-cause...

American Family Physician

https://www.aafp.org/afp/2020/0601/afp20200601p695a.pdf

afp20200601p696.pdf

...age of participants was 65 years, 25% had diabetes mellitus, 33% had a previous myo- cardial infarction, and 9% had a previous stroke or transient ischemic attack. Left main disease was present in 40% and three-vessel disease in 60% of the patients. The primary outcome was all-cause...

American Family Physician

https://www.aafp.org/afp/2020/0601/afp20200601p696.pdf

afp20200601p698.pdf

...age of participants was 65 years, 25% had diabetes mellitus, 33% had a previous myo- cardial infarction, and 9% had a previous stroke or transient ischemic attack. Left main disease was present in 40% and three-vessel disease in 60% of the patients. The primary outcome was all-cause...

American Family Physician

https://www.aafp.org/afp/2020/0601/afp20200601p698.pdf

afp20200615od1.pdf

...9. Holsinger T, Deveau J, Boustani M, et al. Does this patient have demen- tia? JAMA. 2007; 297(21): 2391-2404. 10. Plassman BL, Williams JW Jr, Burke JR, et al. Systematic review: factors associated with risk for and possible prevention of cognitive decline in later life. Ann...

American Family Physician

https://www.aafp.org/afp/2020/0615/afp20200615od1.pdf

afp20200615p713.pdf

...In this issue, the Lown Right Care: Reducing Overuse and Underuse department on the pros and cons of anticoagulation for stroke prevention includes a new section called the Patient Perspec- tive.1 We would like to welcome Helen Haskell and John James in their new roles on American...

American Family Physician

https://www.aafp.org/afp/2020/0615/afp20200615p713.pdf

afp20200615p753.pdf

... D. Mild cognitive impairment and demen- tia interfere with independent daily functioning.  E. Dementia currently affects an esti- mated 8 to 9 million people in the United States. Answers 1. The correct answer is D. The USPSTF found insufficient evidence to assess the...

American Family Physician

https://www.aafp.org/afp/2020/0615/afp20200615p753.pdf

afp20200701p30.pdf

...blood cells for arbitrary hemoglobin or hematocrit thresholds and in the absence of symptoms or active coronary disease, heart failure, or stroke. Society of Hospital Medicine (Adult) Do not transfuse red blood cells in hemodynamically stable, nonbleeding patients in the...

American Family Physician

https://www.aafp.org/afp/2020/0701/afp20200701p30.pdf

afp20200715p115.pdf

...no difference in the rate of major adverse cardiovascular events (i.e., cardiovascular-related death, myocardial infarc- tion, or ischemic stroke) between patients taking dapagliflozin and placebo, trial investigators con- sider the reduction in combined renal outcome as...

American Family Physician

https://www.aafp.org/afp/2020/0715/afp20200715p115.pdf

afp20200801p150.pdf

...Ripping or tearing sensation in neck, diplopia, drop attacks, headache, syncope, transient ischemic attack symptoms, vertigo, vision changes Kernig sign, unilateral decrease in sensation, unilat- eral weakness Urgent referral and imaging (CT or CT angiography) CRP =...

American Family Physician

https://www.aafp.org/afp/2020/0801/afp20200801p150.pdf

afp20200815p247.pdf

...Reduction in Cardiovascular Outcome After Ischemic Stroke with Lower LDL Target, but also Harms; No Change in All-Cause Mortality Clinical Question Does a lower low-density lipoprotein (LDL) tar- get following ischemic stroke reduce the likeli- hood of major adverse...

American Family Physician

https://www.aafp.org/afp/2020/0815/afp20200815p247.pdf

afp20200815p248.pdf

...Reduction in Cardiovascular Outcome After Ischemic Stroke with Lower LDL Target, but also Harms; No Change in All-Cause Mortality Clinical Question Does a lower low-density lipoprotein (LDL) tar- get following ischemic stroke reduce the likeli- hood of major adverse...

American Family Physician

https://www.aafp.org/afp/2020/0815/afp20200815p248.pdf

afp20200815p248a.pdf

...Reduction in Cardiovascular Outcome After Ischemic Stroke with Lower LDL Target, but also Harms; No Change in All-Cause Mortality Clinical Question Does a lower low-density lipoprotein (LDL) tar- get following ischemic stroke reduce the likeli- hood of major adverse...

American Family Physician

https://www.aafp.org/afp/2020/0815/afp20200815p248a.pdf

afp20200901od2.pdf

...Aspirin After Acute Ischemic Stroke John Conway, BS, and Benjamin W. Friedman, MD Details for This Review Study Population: Adults presenting with acute stroke Efficacy End Points: Death or dependence, recurrent stroke, complete recovery from stroke Harm End Points:...

American Family Physician

https://www.aafp.org/afp/2020/0901/afp20200901od2.pdf

afp20200901p271.pdf

...Effectiveness of PPAR Gamma Agonists in Preventing Recurrent Stroke and Other Vascular Events Madhavi Singh, MD; Kristen Grine, DO; and Amy Hays, MD, Penn State University College of Medicine, Hershey, Pennsylvania Author disclosure: No relevant financial affiliations....

American Family Physician

https://www.aafp.org/afp/2020/0901/afp20200901p271.pdf

afp20200915p332.pdf

...for dual antiplatelet therapy after stroke or transient ischemic attack? A 10- to 21-day course of dual antiplatelet ther- apy reduces stroke recurrence and improves quality of life after mild stroke or high-risk transient ischemic attack. Low-dose aspirin and a 300-mg loading dose...

American Family Physician

https://www.aafp.org/afp/2020/0915/afp20200915p332.pdf

afp20200915p335.pdf

...and muscle relax- ants.7 The use of nonopioid medications is often restricted by limited effectiveness or adverse effects, such as bleeding, strokes, and cardiovascular and renal disease with NSAIDs.8 Adjuvant medications such as gabapentin (Neurontin) have been used for nonapproved...

American Family Physician

https://www.aafp.org/afp/2020/0915/afp20200915p335.pdf

afp20200915p347.pdf

...outcome of cardiovascular death, myocardial infarction, or nonfatal stroke compared with those taking placebo (11.2% vs. 14.8%; HR = 0.74; 95% CI, 0.65 to 0.83; NNT = 28 over five years).39 Those taking icosapent also had lower cardio- vascular mortality (4.3% vs. 5.2%; HR = 0.80;...

American Family Physician

https://www.aafp.org/afp/2020/0915/afp20200915p347.pdf

afp20201015od3.pdf

...age, sex, education), smoking status, alcohol intake, and diagnoses of chronic medical conditions (e.g., diabetes mellitus, heart disease, stroke, cancer, chronic bronchitis). In addition to count- ing steps, step intensity was estimated based on extended bouts of stepping and peak...

American Family Physician

https://www.aafp.org/afp/2020/1015/afp20201015od3.pdf

afp20201015od4.pdf

...age, sex, education), smoking status, alcohol intake, and diagnoses of chronic medical conditions (e.g., diabetes mellitus, heart disease, stroke, cancer, chronic bronchitis). In addition to count- ing steps, step intensity was estimated based on extended bouts of stepping and peak...

American Family Physician

https://www.aafp.org/afp/2020/1015/afp20201015od4.pdf

afp20201015od5.pdf

...age, sex, education), smoking status, alcohol intake, and diagnoses of chronic medical conditions (e.g., diabetes mellitus, heart disease, stroke, cancer, chronic bronchitis). In addition to count- ing steps, step intensity was estimated based on extended bouts of stepping and peak...

American Family Physician

https://www.aafp.org/afp/2020/1015/afp20201015od5.pdf

afp20201015od6.pdf

...age, sex, education), smoking status, alcohol intake, and diagnoses of chronic medical conditions (e.g., diabetes mellitus, heart disease, stroke, cancer, chronic bronchitis). In addition to count- ing steps, step intensity was estimated based on extended bouts of stepping and peak...

American Family Physician

https://www.aafp.org/afp/2020/1015/afp20201015od6.pdf

afp20201015p478.pdf

...18 to 49 years of age.19 Thrombosis with thrombocytopenia syn- drome can cause cerebral venous sinus thrombosis, which may present with stroke-like symptoms. Thrombocytope- nia syndrome should not be treated with heparin.19 • Each vaccine is highly effective at preventing...

American Family Physician

https://www.aafp.org/afp/2020/1015/afp20201015p478.pdf

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