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Evaluating the Safety and Effectiveness of New Drugs - American Family Physician

Jul 1, 2010 - Prescribers seek to provide their patients with access to the latest innovations in medicine to maximize their health status. When a new drug comes to market, it often has not been as widely tested as other available therapies, and its effectiveness and safety cannot be fully evaluated....

American Family Physician : Article

https://www.aafp.org/afp/2010/0701/p53.html

Cyanosis in an Older Woman - Photo Quiz - American Family Physician

Jun 15, 2010 - Photo Quiz presents readers with a clinical challenge based on a photograph or other image.

American Family Physician : Photo Quiz

https://www.aafp.org/afp/2010/0615/p1491.html

First-Line Treatment for Hypertension - Cochrane for Clinicians - American Family ...

Jun 1, 2010 - In comparing the effects of thiazide diuretics, beta blockers, angiotensin-converting enzyme (ACE) inhibitors, and calcium channel blockers (CCBs) with placebo, thiazide diuretics lowered mortality and morbidity from stroke, heart attack, and heart failure more than beta blockers.1 ACE ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2010/0601/p1333.html

Hepatitis C: Diagnosis and Treatment - American Family Physician

Jun 1, 2010 - Hepatitis C, a common chronic bloodborne infection, is found in approximately 2 percent of adults in the United States. Chronic infection is associated with serious morbidity and mortality (e.g., cirrhosis, hepatocellular carcinoma). Testing for hepatitis C is recommended for at-risk ...

American Family Physician : Article

https://www.aafp.org/afp/2010/0601/p1351.html

How Health Care Reform Will Affect Family Physicians -- FPM

Jun 1, 2010 - The legislation isn't perfect, but it makes an important point - that primary care deserves more attention.

Family Practice Management : Articles

https://www.aafp.org/fpm/2010/0500/p14.html

Nursing Home Care: Part II. Clinical Aspects - American Family Physician

May 15, 2010 - Understanding the distinctions between the management of clinical problems in nursing homes compared with the community setting helps improve the overall care of nursing home residents. Liberalizing diets helps avoid unintentional weight loss in nursing home residents, although the use ...

American Family Physician : Article

https://www.aafp.org/afp/2010/0515/p1229.html

Primary Care of Adult Survivors of Childhood Cancer - American Family Physician

May 15, 2010 - There are approximately 300,000 survivors of childhood cancer in the United States, and most of them receive their medical care from primary care physicians. Adult survivors of childhood cancer are at considerable risk of long-term morbidity and mortality beyond the recurrence of their ...

American Family Physician : Article

https://www.aafp.org/afp/2010/0515/p1250.html

Febuxostat (Uloric) for Hyperuricemia and Gout - STEPS - American Family Physician

May 15, 2010 - Febuxostat more effectively lowers serum uric acid to goal levels than does allopurinol; however, this benefit is offset by a slightly higher incidence of adverse effects and treatment discontinuation. Until superiority for patient-oriented outcomes is shown in comparative trials with ...

American Family Physician : STEPS

https://www.aafp.org/afp/2010/0515/p1287.html

Prevention, Recognition, and Management of Serotonin Syndrome - American Family Physician

May 1, 2010 - Serotonin syndrome is a potentially life-threatening condition caused by excessive serotonergic activity in the nervous system. It is characterized by mental status changes, autonomic instability, and neuromuscular hyperactivity. Most reported cases of serotonin syndrome are in patients...

American Family Physician : Article

https://www.aafp.org/afp/2010/0501/p1139.html

Tips From Other Journals - American Family Physician

May 1, 2010 - ...and raloxifene increased the risk of thromboembolism (risk ratio = 1.93 and 1.60, respectively) compared with placebo. Tibolone caused more strokes than placebo (risk ratio = 2.19). Risk of coronary heart disease was not increased with any agent. Tamoxifen also increased the risk of...

American Family Physician : Tip

https://www.aafp.org/afp/2010/0501/p1149.html

Pelvic Organ Prolapse - American Family Physician

May 1, 2010 - ...smelling discharge, problems passing urine or stool, or any change in your ability to take care of the pessary (for instance, if you have a stroke or arthritis). What are Kegel exercises? They are exercises to strengthen the muscles of the pelvis. Your doctor can teach you how to do...

American Family Physician : Patient Handout

https://www.aafp.org/afp/2010/0501/p1119.html

Examining the Heart of Family Medicine: Family History - Editorials - American Family ...

Apr 15, 2010 - ...accompanying table) about screening family history for asthma and allergies (atopic disease); diabetes; major depression and mood disorders; stroke; cardiovascular disease; and five common cancers (breast, ovarian, colorectal, prostate, and lung).3 The panel statement,3 evidence...

American Family Physician : Editorials

https://www.aafp.org/afp/2010/0415/p961.html

Diabetes Mellitus: Diagnosis and Screening - American Family Physician

Apr 1, 2010 - Based on etiology, diabetes is classified as type 1 diabetes mellitus, type 2 diabetes mellitus, latent autoimmune diabetes, maturity-onset diabetes of youth, and miscellaneous causes. The diagnosis is based on measurement of A1C level, fasting or random blood glucose level, or oral ...

American Family Physician : Article

https://www.aafp.org/afp/2010/0401/p863.html

Effectiveness of B-Complex Vitamins for Prevention of Cardiovascular Events - Cochrane ...

Apr 1, 2010 - Eight randomized clinical trials that included 24,210 patients did not show a reduction in MI, stroke, or all-cause mortality with B-complex vitamin therapy.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2010/0401/p850.html

Blood Pressure Treatment Targets for Uncomplicated Hypertension - Cochrane for ...

Apr 1, 2010 - To date, there is no evidence to support treating patients with uncomplicated hypertension to blood pressure goals lower than the standard blood pressure target of less than or equal to 140 to 160/90 to 100 mm Hg. In randomized controlled trials, patients treated to lower blood pressure...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2010/0401/p848.html

Latent Autoimmune Diabetes in Adults - Editorials - American Family Physician

Apr 1, 2010 - ...Increased risk of cardiovascular morbidity and mortality related to strokes, acute coronary events, and coronary revascularizations; high incidence rates compared with euglycemic individuals, especially in women Same risk as patients with T2DM Microvascular complications...

American Family Physician : Editorials

https://www.aafp.org/afp/2010/0401/p843.html

An Open Letter to All the Health Plans That Keep Sending Me Letters -- FPM

Apr 1, 2010 - How helpful are all those letters you receive from health plans? Not very, says this family physician.

Family Practice Management : The Last Word

https://www.aafp.org/fpm/2010/0300/p52.html

Predicting the Risk of Bleeding in Patients Taking Warfarin - Point-of-Care Guides - ...

Mar 15, 2010 - When considering anticoagulation therapy in patients with atrial fibrillation or venous thromboembolism (VTE), physicians and patients must balance the benefits of anticoagulation with the risk of bleeding, particularly major bleeding complications. For example, in patients who are at ...

American Family Physician : Point-of-Care Guides

https://www.aafp.org/afp/2010/0315/p780.html

ASCO Updates Guideline on the Use of Pharmacologic Interventions to Reduce Breast ...

Mar 15, 2010 - The American Society of Clinical Oncology's (ASCO) updated guideline addresses: (1) the use of tamoxifen, raloxifene (Evista), aromatase inhibitors, and fenretinide (not available in the United States) versus no pharmacologic intervention to reduce the risk of breast cancer; (2) the ...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2010/0315/p799.html

Beta Blockers and Noncardiac Surgery: Why the POISE Study Alone Should Not Change Your ...

Mar 15, 2010 - Should we stop using beta blockers to prevent myocardial infarction in persons undergoing noncardiac surgery? The data remain inconclusive. Although the POISE study is an important contribution to the literature, it uses a protocol that is unrealistic and should not change current ...

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2010/0315/p717.html

Stress Incontinence - Clinical Evidence Handbook - American Family Physician

Mar 15, 2010 - What are the effects of surgical and nonsurgical treatments for women with stress incontinence?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2010/0315/p773.html

ACC and AHA Update on Chronic Heart Failure Guidelines - Practice Guidelines - American...

Mar 1, 2010 - In 2009, the American College of Cardiology (ACC) and the American Heart Association (AHA) published a focused update of the ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2010/0301/p654.html

Discussing Treatment Options with Patients - Curbside Consultation - American Family ...

Mar 1, 2010 - Sometimes it may seem easier to inject a subacromial bursa or aspirate a knee joint than to engage in shared decision making with your patients about the use of aspirin for coronary artery disease prevention or a PSA test for prostate cancer screening. The path that led to the disparate...

American Family Physician : Curbside Consultation

https://www.aafp.org/afp/2010/0301/p645.html

AAFP News - Mar 1, 2010 - American Family Physician

Mar 1, 2010 - Selected policy and health issues news briefs from AAFP News Now.

American Family Physician : AAFP News: AFP Edition

https://www.aafp.org/afp/2010/0301/p581.html

Management of Erectile Dysfunction - American Family Physician

Feb 1, 2010 - Erectile dysfunction (ED) is the most common sexual problem in men. The incidence increases with age and affects up to one third of men throughout their lives. It causes a substantial negative impact on intimate relationships, quality of life, and self-esteem. History and physical ...

American Family Physician : Article

https://www.aafp.org/afp/2010/0201/p305.html

Secondary Prevention of Coronary Artery Disease - American Family Physician

Feb 1, 2010 - Coronary artery disease is the leading cause of mortality in the United States. In patients who have had a myocardial infarction or revascularization procedure, secondary prevention of coronary artery disease by comprehensive risk factor modification reduces mortality, decreases ...

American Family Physician : Article

https://www.aafp.org/afp/2010/0201/p289.html

FDA Boxed Warnings: How to Prescribe Drugs Safely - American Family Physician

Feb 1, 2010 - Boxed warnings, commonly referred to as 'black box' warnings, are issued by the U.S. Food and Drug Administration and featured in the labeling of drugs associated with serious adverse reactions. These safety concerns are typically identified through the Adverse Event Reporting System ...

American Family Physician : Article

https://www.aafp.org/afp/2010/0201/p298.html

Leg Compression and Pharmacologic Prophylaxis for Venous Thromboembolism Prevention in ...

Feb 1, 2010 - Based on high-quality evidence, the Cochrane review showed that combining IPC with pharmacologic prophylaxis was more effective than a single preventative measure for preventing deep venous thrombosis (DVT), and more effective than IPC alone for preventing pulmonary embolism (PE).

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2010/0201/p284.html

Erectile Dysfunction - American Family Physician

Feb 1, 2010 - ...nerves and blood vessels in the penis. This allows the penis to fill with blood. Some medical conditions may block these signals, including strokes, spinal injuries, pelvic trauma, Parkinson disease, and multiple sclerosis. Prostate or pelvic surgery, and pelvic nerve damage from...

American Family Physician : Patient Handout

https://www.aafp.org/afp/2010/0201/p313.html

Outdoor Air Pollutants and Patient Health - American Family Physician

Jan 15, 2010 - Almost 160 million persons live in areas of the United States that exceed federal health-based air pollution standards. The two air pollutants that most commonly exceed standards are ozone and particulate matter. Ozone and particulate matter can harm anyone if levels are sufficiently ...

American Family Physician : Article

https://www.aafp.org/afp/2010/0115/p175.html

AAFP News - Jan 15, 2010 - American Family Physician

Jan 15, 2010 - Selected policy and health issues news briefs from AAFP News Now.

American Family Physician : AAFP News: AFP Edition

https://www.aafp.org/afp/2010/0115/p103.html

Physical Activity Guidelines for Older Adults - American Family Physician

Jan 1, 2010 - Few older adults in the United States achieve the minimum recommended amount of physical activity. Lack of physical activity contributes to many chronic diseases that occur in older adults, including heart disease, stroke, diabetes mellitus, lung disease, Alzheimer disease, ...

American Family Physician : Article

https://www.aafp.org/afp/2010/0101/p55.html

Cervical Radiculopathy: Nonoperative Management of Neck Pain and Radicular Symptoms - ...

Jan 1, 2010 - Cervical radiculopathy is a disease process marked by nerve compression from herniated disk material or arthritic bone spurs. This impingement typically produces neck and radiating arm pain or numbness, sensory deficits, or motor dysfunction in the neck and upper extremities. Magnetic ...

American Family Physician : Article

https://www.aafp.org/afp/2010/0101/p33.html

NSAID Prescribing Precautions - American Family Physician

Dec 15, 2009 - Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used, but have risks associated with their use, including significant upper gastrointestinal tract bleeding. Older persons, persons taking anticoagulants, and persons with a history of upper gastrointestinal tract bleeding ...

American Family Physician : Article

https://www.aafp.org/afp/2009/1215/p1371.html

Sex-Based Differences in Drug Activity - American Family Physician

Dec 1, 2009 - Physiologic differences between men and women affect drug activity, including pharmacokinetics and pharmacodynamics. Pharmacokinetics in women is affected by lower body weight, slower gastrointestinal motility, less intestinal enzymatic activity, and slower glomerular filtration rate. ...

American Family Physician : Article

https://www.aafp.org/afp/2009/1201/p1254.html

Is Telmisartan Effective for Stroke Prevention? - AFP Journal Club - American Family ...

Nov 15, 2009 - Does telmisartan therapy after stroke prevent recurrence and adverse cardiovascular events? Despite lowering blood pressure, telmisartan did not provide preventative benefit. This study reflects problems with publication bias and that surrogate markers, such as blood pressure control, ...

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2009/1115/p1042.html

Catheter Ablation of Supraventricular Arrhythmias and Atrial Fibrilation - American ...

Nov 15, 2009 - Supraventricular arrhythmias are relatively common, often persistent, and rarely life-threatening cardiac rhythm disturbances that arise from the sinus node, atrial tissue, or junctional sites between the atria and ventricles. The term

American Family Physician : Article

https://www.aafp.org/afp/2009/1115/p1089.html

Screening for Type 2 Diabetes Mellitus in Adults: Recommendation Statement - U.S. ...

Nov 15, 2009 - The U.S. Preventive Services Task Force (USPSTF) recommends screening for type 2 diabetes mellitus in asymptomatic adults with sustained blood pressure (treated or untreated) greater than 135/80 mm Hg.

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2009/1115/p1138.html

Screening for Type 2 Diabetes Mellitus in Adults - Putting Prevention into Practice - ...

Nov 15, 2009 - Case study: A 50-year-old woman with a history of hyperlipidemia visits your office for a physical examination. Her blood pressure is 140/82 mm Hg, and her body mass index is 30 kg per m2.

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2009/1115/p1141.html

Correction - Corrections - American Family Physician

Nov 15, 2009 - ...Previous: Is Telmisartan Effective for Stroke Prevention? Next: Family Physicians' Present and Future Role in Caring for Older Patients View the full table of contents >> Home / Journals / afp / Vol. 80/No. 10(November 15, 2009) / Corrections: Correction...

American Family Physician : Corrections

https://www.aafp.org/afp/2009/1115/p1058.html

Tips From Other Journals - American Family Physician

Nov 15, 2009 - ...pioglitazone (Actos)—as a related drug—might also pose similar risks. One study reported a lower incidence of a combined end point of MI, stroke, and cardiovascular mortality with pioglitazone, but did not examine these outcomes individually. Head-to-head comparisons of these two...

American Family Physician : Tip

https://www.aafp.org/afp/2009/1115/p1165.html

Tips From Other Journals - American Family Physician

Nov 15, 2009 - ...trials with at least one year of follow-up were reviewed. Studies were excluded if they included patients with organ transplantation or stroke, or who were receiving corticosteroid therapy. The primary outcome was the relative risk of a nonvertebral or hip fracture in persons...

American Family Physician : Tip

https://www.aafp.org/afp/2009/1115/p1153.html

AAFP News - Nov 15, 2009 - American Family Physician

Nov 15, 2009 - Selected policy and health issues news briefs from AAFP News Now.

American Family Physician : AAFP News: AFP Edition

https://www.aafp.org/afp/2009/1115/p1039.html

Tips From Other Journals - American Family Physician

Nov 1, 2009 - ...surgery. Outcomes of interest included 30-day all-cause mortality; cardiovascular mortality; nonfatal myocardial infarction (MI); nonfatal stroke; heart failure; and perioperative bradycardia, hypotension, and bronchospasm. Results: Thirty-three trials including 12,306 patients...

American Family Physician : Tip

https://www.aafp.org/afp/2009/1101/p1000a.html

Tips From Other Journals - American Family Physician

Nov 1, 2009 - ...Background: Persons with diabetes or peripheral arterial disease have markedly increased risks of myocardial infarction (MI), stroke, and death. Because aspirin is an effective antiplatelet agent for secondary prevention of cardiovascular events in these populations, its use has...

American Family Physician : Tip

https://www.aafp.org/afp/2009/1101/p1000.html

Tips From Other Journals - American Family Physician

Nov 1, 2009 - ...of age with type 2 diabetes were eligible. Exclusion criteria included known coronary vascular disease; history of stroke, cerebral hemorrhage, or transient ischemic attacks; electrocardiographic changes consistent with ischemia or previous infarct; atrial fibrillation; peripheral...

American Family Physician : Tip

https://www.aafp.org/afp/2009/1101/p997a.html

Recognition and Management of Vitamin D Deficiency - American Family Physician

Oct 15, 2009 - Vitamin D deficiency affects persons of all ages. Common manifestations of vitamin D deficiency are symmetric low back pain, proximal muscle weakness, muscle aches, and throbbing bone pain elicited with pressure over the sternum or tibia. A 25-hydroxyvitamin D level should be obtained ...

American Family Physician : Article

https://www.aafp.org/afp/2009/1015/p841.html

Tips From Other Journals - American Family Physician

Oct 15, 2009 - ...thiazide diuretics were at least as effective as newer drug classes in preventing cardiovascular disease (CVD), including heart failure and stroke, in high-risk patients with hypertension. Wright Jr. and colleagues reevaluated the initial ALLHAT findings in light of subsequent...

American Family Physician : Tip

https://www.aafp.org/afp/2009/1015/p882.html

Five Communication Strategies to Promote Self-Management of Chronic Illness -- FPM

Oct 1, 2009 - How you communicate with your patients can enhance - or inhibit - their ability to manage their chronic illnesses.

Family Practice Management : Articles

https://www.aafp.org/fpm/2009/0900/p12.html

Is the San Francisco Syncope Rule Reliable? - AFP Journal Club - American Family Physician

Sep 15, 2009 - Can the San Francisco Syncope Rule successfully determine which patients can be safely discharged after an acute syncopal episode? External validation suggests that the sensitivity of the rule is lower than first reported. Physicians need to apply their clinical acumen and override the ...

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2009/0915/p558.html

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