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Fewer Deaths/Strokes/Revascularizations with Metformin Than Glipizide - POEMs - ...

Jan 15, 2014 - Over five years, treatment with metformin for three years, with other hypoglycemics as needed, reduced the likelihood of death, nonfatal stroke, or the need for vascularization compared with treatment beginning with glipizide (Glucotrol). Cardiovascular events were not individually ...

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0115/p131.html

Eye Emergencies - American Family Physician Restricted content. Login required.

Nov 1, 2020 - Central retinal artery occlusions, chemical injuries, mechanical globe injuries, and retinal detachments are eye emergencies that can result in permanent vision loss if not treated urgently. Family physicians should be able to recognize the signs and symptoms of each condition and be ...

American Family Physician : Article

https://www.aafp.org/afp/2020/1101/p539.html

Stroke: Part II. Management of Acute Ischemic Stroke - American Family Physician

May 15, 1999 - Optimal treatment of the patient who has sustained an acute ischemic stroke requires rapid assessment and early intervention. The leisurely approach to acute stroke management sometimes taken in the past should be replaced by an approach that treats stroke as a true medical emergency. ...

American Family Physician : Article

https://www.aafp.org/afp/1999/0515/p2828.html

Targeted Cancer Therapies - American Family Physician Restricted content. Login required.

Feb 1, 2021 - Targeted cancer therapies involve chemotherapeutic agents that attack, directly or indirectly, a specific genetic biomarker found in a given cancer. Targeted oncology includes monoclonal antibodies, small molecule inhibitors, antibody-drug conjugates, and immunotherapy. For example, the...

American Family Physician : Article

https://www.aafp.org/afp/2021/0201/p155.html

Insulin for Glycemic Control in Acute Ischemic Stroke - Cochrane for Clinicians - ...

Dec 1, 2012 - Administering insulin to maintain glycemic control does not improve the rates of mortality or dependency, or the final neurologic outcome after an acute ischemic stroke. Additionally, in randomized controlled trials, patients in the intervention groups (those under tight glycemic ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2012/1201/p1008.html

Stroke: Part I. A Clinical Update on Prevention - American Family Physician

May 1, 1999 - Clinical trials conducted during the past five years have yielded important results that have allowed us to refine our approach to stroke prevention. Treatment of isolated systolic hypertension prevents stroke and is generally well tolerated. New antiplatelet agents (clopidogrel and the...

American Family Physician : Article

https://www.aafp.org/afp/1999/0501/p2475.html

Practical Considerations in the Early Treatment of Ischemic Stroke - American Family ...

Jan 1, 1998 - Successful treatment of patients with ischemic stroke depends on the ability to treat within three hours of onset, because tissue plasminogen activator has not yet been proved effective beyond this time frame. The two major causes of delay in treatment are failure, on the part of the ...

American Family Physician : Article

https://www.aafp.org/afp/1998/0101/p73.html

Update on Vitamin Supplements for the Prevention of Coronary Disease and Stroke - ...

Sep 15, 2000 - Dietary antioxidants and folic acid may play a role in the pathophysiology of coronary disease and stroke. We review patient-oriented evidence on the effectiveness of supplementation with antioxidants and/or folic acid in the prevention of myocardial infarction and stroke. Observational...

American Family Physician : Article

https://www.aafp.org/afp/2000/0915/p1359.html

Transient Ischemic Attack: The Rules Have Changed - AFP Journal Club - American Family ...

Jun 15, 2012 - This scientific guideline includes three game changers for physicians regarding TIA. The Journal Club authors discuss why physicians should be wary of clinical guidelines that are based on expert opinion.

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2012/0615/p1179.html

Management of Sickle Cell Disease: Recommendations from the 2014 Expert Panel Report - ...

Dec 15, 2015 - Family physicians are the primary and sometimes only health care resource for families affected by sickle cell disease. Recently published guidelines provide important recommendations for health maintenance, acute care, and monitoring of disease-modifying therapy in persons with this ...

American Family Physician : Article

https://www.aafp.org/afp/2015/1215/p1069.html

Rivaroxaban vs. Warfarin for Stroke Prevention in Patients with Nonvalvular Atrial ...

Mar 15, 2012 - How does rivaroxaban compare with warfarin for stroke prevention in patients with nonvalvular atrial fibrillation? This study concluded that rivaroxaban is noninferior to warfarin. However, noninferiority trials do not meet the same rigorous design and statistical format of traditional ...

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2012/0315/p577.html

Dabigatran (Pradaxa) for Prevention of Stroke in Atrial Fibrillation - STEPS - American...

Dec 15, 2011 - Dabigatran is superior to warfarin for stroke prevention in patients with atrial fibrillation, with similar rates of major bleeding. Because it does not require laboratory monitoring, dabigatran therapy is less complicated than warfarin therapy, but it costs significantly more.

American Family Physician : STEPS

https://www.aafp.org/afp/2011/1215/p1397.html

Choosing Wisely: Don’t order formal swallow evaluation in stroke patients unless they ...

Don’t order formal swallow evaluation in stroke patients unless they fail their initial swallow screen.

American Family Physician : Choosing Wisely Recommendations

https://www.aafp.org/afp/recommendations/viewRecommendation.htm?recommendationId=325

AAN Releases Guideline on Magnetic Resonance Imaging for Diagnosing Acute Ischemic ...

Feb 15, 2011 - Computed tomography (CT) is the diagnostic standard for acute stroke even though its accuracy has not been formally established. Its sensitivity for diagnosing ischemic stroke in the initial hours is limited; therefore, improved accuracy is needed to develop and provide optimal stroke ...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2011/0215/p483.html

Choosing Wisely: Don’t routinely use seizure prophylaxis in patients following ischemic...

Don’t routinely use seizure prophylaxis in patients following ischemic stroke.

American Family Physician : Choosing Wisely Recommendations

https://www.aafp.org/afp/recommendations/viewRecommendation.htm?recommendationId=209

Choosing Wisely: Avoid transfusions of red blood cells for arbitrary hemoglobin or ...

Avoid transfusions of red blood cells for arbitrary hemoglobin or hematocrit thresholds and in the absence of symptoms or active coronary disease, heart failure, or stroke.

American Family Physician : Choosing Wisely Recommendations

https://www.aafp.org/afp/recommendations/viewRecommendation.htm?recommendationId=31

Aspirin in Patients with Actue Ischemic Stroke - FPIN's Clinical Inquiries - American ...

Feb 1, 2009 - Aspirin in a daily dose of 160 to 300 mg initiated within 48 hours of symptom onset results in a net decrease in morbidity and mortality caused by acute ischemic stroke, based on a systematic review), regardless of the availability of computed tomography (CT).

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2009/0201/p226.html

Is Telmisartan Effective for Stroke Prevention? - AFP Journal Club - American Family ...

Nov 15, 2009 - Does telmisartan therapy after stroke prevent recurrence and adverse cardiovascular events? Despite lowering blood pressure, telmisartan did not provide preventative benefit. This study reflects problems with publication bias and that surrogate markers, such as blood pressure control, ...

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2009/1115/p1042.html

Health Maintenance in Postmenopausal Women - American Family Physician

May 1, 2017 - Cardiovascular disease is the leading cause of death and disability in postmenopausal women older than 50 years. Clinicians should use the pooled cohort risk assessment equations or another risk calculator every three to five years to estimate a woman’s 10-year risk of atherosclerotic ...

American Family Physician : Article

https://www.aafp.org/afp/2017/0501/p561.html

Tinnitus: Diagnosis and Management - American Family Physician Restricted content. Login required.

Jun 1, 2021 - Tinnitus is the sensation of hearing a sound in the absence of an internal or external source and is a common problem encountered in primary care. Most cases of tinnitus are benign and idiopathic and are strongly associated with sensorineural hearing loss. A standard workup begins with ...

American Family Physician : Article

https://www.aafp.org/afp/2021/0601/p663.html

AFP By Topic - American Family Physician

Jun 15, 2021 - Editors' Choice of Best Available Content

American Family Physician : AFP By Topic

https://www.aafp.org/afp/topicModules/viewAll.htm

Chronic Kidney Disease: Detection and Evaluation - American Family Physician

Nov 15, 2011 - Chronic kidney disease affects an estimated 27 million adults in the United States, and is associated with significantly increased risk of cardiovascular disease and stroke. Patients should be assessed annually to determine whether they are at increased risk of developing chronic kidney...

American Family Physician : Article

https://www.aafp.org/afp/2011/1115/p1138.html

Predicting Prognoses in Patients with Acute Stroke - Point-of-Care Guides - American ...

Jun 15, 2008 - A number of clinical decision models and scoring systems have been developed and validated to assist physicians in assessing the prognosis of patients with acute stroke.

American Family Physician : Point-of-Care Guides

https://www.aafp.org/afp/2008/0615/p1719.html

Treatment of Acute Ischemic Stroke with t-PA - AFP Journal Club - American Family ...

Apr 1, 2008 - Does the widespread use of the thrombolytic tissue plasminogen activator (t-PA) more beneficial or harmful in patients with acute stroke? The benefits must be balanced against the harms. Informed consent is necessary when making the decision.

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2008/0401/p901.html

Atrial Fibrillation: Diagnosis and Treatment - American Family Physician

Jan 1, 2011 - Atrial fibrillation is the most common cardiac arrhythmia. It impairs cardiac function and increases the risk of stroke. The incidence of atrial fibrillation increases with age. Key treatment issues include deciding when to restore normal sinus rhythm, when to control rate only, and how...

American Family Physician : Article

https://www.aafp.org/afp/2011/0101/p61.html

Top 20 Research Studies of 2015 for Primary Care Physicians - American Family Physician

May 1, 2016 - In 2015, a group of primary care clinicians with expertise in evidence-based practice performed monthly surveillance of more than 110 English-language clinical research journals. They identified 251 studies that addressed a primary care question and had the potential to change practice ...

American Family Physician : Article

https://www.aafp.org/afp/2016/0501/p756.html

Health Maintenance in Women - American Family Physician

Jan 1, 2013 - The health maintenance examination is an opportunity to focus on disease prevention and health promotion. The patient history should include screening for tobacco use, alcohol misuse, intimate partner violence, and depression. Premenopausal women should receive preconception counseling ...

American Family Physician : Article

https://www.aafp.org/afp/2013/0101/p30.html

Decompression Surgery, Fabric Masks, Heat Stroke, e-Cigarette Use - AFP Clinical ...

Jun 1, 2020 - Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.

American Family Physician : AFP Clinical Answers

https://www.aafp.org/afp/2020/0601/p648.html

Predicting Short-term Risk of Stroke After TIA - Point-of-Care Guides - American Family...

Sep 15, 2006 - Five to 10 percent of patients presenting with TIA will have a stroke within the following week. Because guidelines do not mandate hospitalization for patients who have had a TIA or suspected TIA,4,5 validated clinical prediction rules may be used to identify patients who should ...

American Family Physician : Point-of-Care Guides

https://www.aafp.org/afp/2006/0915/p1001.html

Screening for Atrial Fibrillation to Initiate Stroke-Protective Therapy - Letters to ...

Jan 1, 2020 - ...Screening for Atrial Fibrillation to Initiate Stroke-Protective Therapy Am Fam Physician. 2020 Jan 1;101(1):6-7. Original Article: Downsides of Detecting Atrial Fibrillation in Asymptomatic Patients [Editorials] Issue Date: March 15, 2019 See additional reader comments at:...

American Family Physician : Letter

https://www.aafp.org/afp/2020/0101/p6.html

Occupational Therapy Improves Activities of Daily Living After Stroke - Cochrane for ...

Jun 1, 2007 - Compared with standard rehabilitation, ADL-based occupational therapy significantly decreases death or institutionalization and deterioration in the ability to perform ADL after stroke. The optimal length and type of therapy is not well defined.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0601/p1651.html

Warfarin for Prevention of Ischemic Stroke Recurrence? - FPIN's Clinical Inquiries - ...

Jun 1, 2006 - There is no evidence that anticoagulation with warfarin, initiated after a noncardioembolic ischemic stroke, significantly reduces stroke recurrence. Furthermore, anticoagulation significantly increases the risk of fatal and nonfatal hemorrhagic stroke and extracranial hemorrhage in ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2006/0601/p2011.html

Asthma, Back and Neck Pain, Pain During Labor, TIA, CBT for Anxiety - AFP Clinical ...

Aug 15, 2019 - Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.

American Family Physician : AFP Clinical Answers

https://www.aafp.org/afp/2019/0815/p208.html

Dapagliflozin in High-Risk Type 2 Diabetes Reduces Hospitalization for Heart Failure ...

Aug 1, 2019 - The only cardiovascular benefit to treatment with dapagliflozin was a reduction in the likelihood of hospitalization; 125 patients would need to be treated for 10 years to prevent one hospitalization.

American Family Physician : POEMs

https://www.aafp.org/afp/2019/0801/p184.html

Postoperative Pain, Acute Stroke, Hormone Therapy, Diet to Improve Cardiovascular Risk,...

May 15, 2019 - Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.

American Family Physician : AFP Clinical Answers

https://www.aafp.org/afp/2019/0515/p606.html

Pharmacologic Treatment of Hyperlipidemia - American Family Physician

Sep 1, 2011 - Pharmacologic treatment of hyperlipidemia in conjunction with therapeutic lifestyle changes can be used for both primary and secondary prevention of cardiovascular disease. Statins have the most convincing data for primary prevention, especially for higher risk patients. Therefore, risk...

American Family Physician : Article

https://www.aafp.org/afp/2011/0901/p551.html

Recognition and Evaluation of Nontraumatic Subarachnoid Hemorrhage and Ruptured ...

Oct 1, 2013 - Swift diagnosis and treatment are critical for good outcomes in patients with nontraumatic subarachnoid hemorrhage, which is usually caused by a ruptured aneurysm. This type of stroke often results in death or disability. Rates of misdiagnosis and treatment delays for subarachnoid ...

American Family Physician : Article

https://www.aafp.org/afp/2013/1001/p451.html

Polycythemia Vera: Rapid Evidence Review - American Family Physician Restricted content. Login required.

Jun 1, 2021 - Polycythemia vera is one of three stem-cell–derived myeloid malignancies commonly known as myeloproliferative neoplasms. It is characterized by erythrocytosis, often with associated leukocytosis and thrombocytosis. It has a significant negative impact on overall mortality and morbidity ...

American Family Physician : Article

https://www.aafp.org/afp/2021/0601/p680.html

JNC8 Guidelines for the Management of Hypertension in Adults - Practice Guidelines - ...

Oct 1, 2014 - Hypertension is one of the most important preventable contributors to disease and death in the United States, leading to myocardial infarction, stroke, and renal failure when it is not detected early and treated appropriately. The Eighth Joint National Committee (JNC 8) recently ...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2014/1001/p503.html

Contraception Choices in Women with Underlying Medical Conditions - American Family ...

Sep 15, 2010 - Primary care physicians often prescribe contraceptives to women of reproductive age with comorbidities. Novel delivery systems (e.g., contraceptive patch, contraceptive ring, single-rod implantable device) may change traditional risk and benefit profiles in women with comorbidities. ...

American Family Physician : Article

https://www.aafp.org/afp/2010/0915/p621.html

Pain In the Quiet (Not Red) Eye - American Family Physician

Jul 1, 2010 - Although eye pain is often accompanied by redness or injection, pain can also occur with a quiet eye. Pain in a quiet eye can be the first sign of a vision-threatening condition, a more benign ophthalmologic condition, or a nonophthalmologic condition. Acute narrow-angle glaucoma is an ...

American Family Physician : Article

https://www.aafp.org/afp/2010/0701/p69.html

The Mental Status Examination - American Family Physician

Oct 15, 2016 - The mental status examination includes general observations made during the clinical encounter, as well as specific testing based on the needs of the patient and physician. Multiple cognitive functions may be tested, including attention, executive functioning, gnosia, language, memory, ...

American Family Physician : Article

https://www.aafp.org/afp/2016/1015/p635.html

Appropriate and Safe Use of Diagnostic Imaging - American Family Physician

Apr 1, 2013 - Risks of diagnostic imaging include cancer from radiation exposure and nephrogenic systemic fibrosis. The increase in volume of imaging between 1980 and 2006 has led to a sixfold increase in annual per capita radiation exposure. It is predicted that 2 percent of future cancers will be ...

American Family Physician : Article

https://www.aafp.org/afp/2013/0401/p494.html

Exercise Stress Testing: Indications and Common Questions - American Family Physician

Sep 1, 2017 - Exercise stress testing is a validated diagnostic test for coronary artery disease in symptomatic patients, and is used in the evaluation of patients with known cardiac disease. Testing of asymptomatic patients is generally not indicated. It may be performed in select deconditioned ...

American Family Physician : Article

https://www.aafp.org/afp/2017/0901/p293.html

Hyperlipidemia - American Family Physician

Mar 15, 2021 - This collection features AFP content on hyperlipidemia and related issues, including dyslipidemia, hypercholesterolemia, hypertriglyceridemia, kidney disease, lipid disorders, metabolic syndrome, statins, and triglyceride levels. This collection features AFP content on hyperlipidemia ...

American Family Physician : AFP By Topic

https://www.aafp.org/afp/topicModules/viewTopicModule.htm?topicModuleId=13

Dizziness: Approach to Evaluation and Management - American Family Physician

Feb 1, 2017 - Dizziness is a common yet imprecise symptom. It was traditionally divided into four categories based on the patient’s history: vertigo, presyncope, disequilibrium, and light-headedness. However, the distinction between these symptoms is of limited clinical usefulness. Patients have ...

American Family Physician : Article

https://www.aafp.org/afp/2017/0201/p154.html

Acute and Chronic Urticaria: Evaluation and Treatment - American Family Physician

Jun 1, 2017 - Urticaria commonly presents with intensely pruritic wheals, sometimes with edema of the subcutaneous or interstitial tissue. It has a lifetime prevalence of about 20%. Although often self-limited and benign, it can cause significant discomfort, continue for months to years, and ...

American Family Physician : Article

https://www.aafp.org/afp/2017/0601/p717.html

Acute Migraine Headache: Treatment Strategies - American Family Physician

Feb 15, 2018 - Migraine is a primary headache disorder characterized by recurrent attacks. Acetaminophen, nonsteroidal anti-inflammatory drugs, triptans, antiemetics, ergot alkaloids, and combination analgesics have evidence supporting their effectiveness in the treatment of migraine. Acetaminophen ...

American Family Physician : Article

https://www.aafp.org/afp/2018/0215/p243.html

Polypharmacy: Evaluating Risks and Deprescribing - American Family Physician

Jul 1, 2019 - Polypharmacy, defined as regular use of at least five medications, is common in older adults and younger at-risk populations and increases the risk of adverse medical outcomes. There are several risk factors that can lead to polypharmacy. Patient-related factors include having multiple ...

American Family Physician : Article

https://www.aafp.org/afp/2019/0701/p32.html

Type 2 Diabetes Therapies: A STEPS Approach - American Family Physician

Feb 15, 2019 - A concise way to evaluate pharmacotherapy options for type 2 diabetes mellitus is to use the five patient-oriented STEPS criteria: safety, tolerability, efficacy, price, and simplicity. The first-line treatment option, metformin, is safe and fairly well-tolerated, has excellent ...

American Family Physician : Article

https://www.aafp.org/afp/2019/0215/p237.html

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