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hypertension

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Statins for Non-Dialysis Chronic Kidney Disease - Cochrane for Clinicians - American ...

Jan 1, 2010 - When taken over a five-year period, statins significantly reduce all-cause mortality (number needed to treat [NNT] = 56), cardiovascular mortality (NNT = 86), and nonfatal cardiovascular events (NNT = 25).

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2010/0101/p27.html

Stimulants, ADHD, and the Heart - Editorials - American Family Physician

May 15, 2009 - ...Next: Evaluation and Management of the Patient with Difficult-to-Control or Resistant Hypertension View the full table of contents >> Home / Journals / afp / Vol. 79/No. 10(May 15, 2009) / Editorials: Stimulants, ADHD, and the Heart...

American Family Physician : Editorials

https://www.aafp.org/afp/2009/0515/p846.html

Stroke: Part II. Management of Acute Ischemic Stroke - American Family Physician

May 15, 1999 - Optimal treatment of the patient who has sustained an acute ischemic stroke requires rapid assessment and early intervention. The leisurely approach to acute stroke management sometimes taken in the past should be replaced by an approach that treats stroke as a true medical emergency. ...

American Family Physician : Article

https://www.aafp.org/afp/1999/0515/p2828.html

Subacute Management of Ischemic Stroke - American Family Physician

Dec 15, 2011 - Ischemic stroke is the third leading cause of death in the United States and a common reason for hospitalization. The subacute period after a stroke refers to the time when the decision to not employ thrombolytics is made up until two weeks after the stroke occurred. Family physicians ...

American Family Physician : Article

https://www.aafp.org/afp/2011/1215/p1383.html

Subclinical Hypothyroidism - Cochrane for Clinicians - American Family Physician

Apr 1, 2008 - Although there is evidence that thyroid hormone therapy in patients with subclinical hypothyroidism may improve lipid profiles, cognitive function, and echographic left ventricular function, there is no evidence that this will decrease morbidity or mortality.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2008/0401/p953.html

Successful Management of the Obese Patient - American Family Physician

Jun 15, 2000 - Obesity is a chronic disease that affects a substantial number of Americans. Obesity significantly increases a person's risk of cardiovascular diseases and morbidity. Modification of lifestyle behaviors that contribute to obesity (e.g., inappropriate diet and inactivity) is the ...

American Family Physician : Article

https://www.aafp.org/afp/2000/0615/p3615.html

Surgical and Nonsurgical Management of Gallstones - American Family Physician

May 15, 2014 - Cholelithiasis, or gallstones, is one of the most common and costly of all the gastrointestinal diseases. The incidence of gallstones increases with age. At-risk populations include persons with diabetes mellitus, persons who are obese, women, rapid weight cyclers, and patients on ...

American Family Physician : Article

https://www.aafp.org/afp/2014/0515/p795.html

Systolic Blood Pressure of At Least 140 mm Hg Best Place to Begin Treatment - POEMs - ...

Aug 15, 2018 - Beginning antihypertensive treatment when the systolic blood pressure is greater than 140 mm Hg delays death and prevents major cardiovascular events in some persons without preexisting heart disease; in patients with existing heart disease, it prevents further events, but does not ...

American Family Physician : POEMs

https://www.aafp.org/afp/2018/0815/p249.html

Systolic BP of 120 Instead of 140 in High-Risk Older Patients Without Diabetes Leads to...

Mar 15, 2016 - In this group of older patients (mean age = 68 years) who do not have diabetes but are at high risk of cardiovascular disease, a more aggressive systolic BP target of 120 mm Hg instead of 140 mm Hg led to benefits (lower all-cause mortality, lower cardiovascular mortality, less heart ...

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0315/p520a.html

Tapering Long-Term Opioid Therapy - Curbside Consultation - American Family Physician

Jan 1, 2020 - My patient is a 54-year-old construction worker who has been taking prescribed opioids for more than a decade for chronic knee and back pain.

American Family Physician : Curbside Consultation

https://www.aafp.org/afp/2020/0101/p49.html

Targeted Therapies: A New Generation of Cancer Treatments - American Family Physician

Feb 1, 2008 - Targeted therapies, which include monoclonal antibodies and small molecule inhibitors, have significantly changed the treatment of cancer over the past 10 years. These drugs are now a component of therapy for many common malignancies, including breast, colorectal, lung, and pancreatic ...

American Family Physician : Article

https://www.aafp.org/afp/2008/0201/p311.html

Testosterone Therapy: Review of Clinical Applications - American Family Physician

Oct 1, 2017 - Testosterone therapy is increasingly common in the United States, and many of these prescriptions are written by primary care physicians. There is conflicting evidence on the benefit of male testosterone therapy for age-related declines in testosterone. Physicians should not measure ...

American Family Physician : Article

https://www.aafp.org/afp/2017/1001/p441.html

The "ARB-MI Paradox": Real or a Fluke? - AFP Journal Club - American Family Physician

Jul 15, 2012 - The Journal Club authors discuss what factors make this meta-analysis, designed to determine whether the ARB-MI paradox is real or a statistical fluke, successful.

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2012/0715/p136.html

The Calcium Channel Antagonist Controversy - Editorials - American Family Physician

Apr 1, 1998 - ...their introduction in the mid-1980s, the calcium channel antagonists became an increasingly popular first choice for the treatment of hypertension. Patients liked them for various reasons: they are effective and easy to take (a once-daily regimen); they do not cause side effects,...

American Family Physician : Editorials

https://www.aafp.org/afp/1998/0401/p1484.html

The Costs of Helping Patients with Type 1 Diabetes Achieve Tight Control - Editorials -...

Nov 1, 1999 - ...and secondary interventions to prevent or ameliorate these complications, and screening for and managing comorbid conditions (e.g., hypertension and hyperlipidemia). Reasonable targets for tight control have been defined as a mean blood glucose level of 155 mg per dL (8.6 mmol per...

American Family Physician : Editorials

https://www.aafp.org/afp/1999/1101/p1914.html

The Effect of Cytochrome P450 Metabolism on Drug Response, Interactions, and Adverse ...

Aug 1, 2007 - Cytochrome P450 enzymes are essential for the metabolism of many medications. Although this class has more than 50 enzymes, six of them metabolize 90 percent of drugs, with the two most significant enzymes being CYP3A4 and CYP2D6. Genetic variability (polymorphism) in these enzymes may ...

American Family Physician : Article

https://www.aafp.org/afp/2007/0801/p391.html

The Importance of Beta Blockers in the Treatment of Heart Failure - American Family ...

Dec 1, 2000 - Heart failure, the only cardiovascular disease with an increasing incidence, is associated with significant mortality and poses a considerable economic burden. Traditionally, beta blockers have been considered to be contraindicated in patients with heart failure. Recently, however, ...

American Family Physician : Article

https://www.aafp.org/afp/2000/1201/p2453.html

The JUPITER Study: Biomarkers Plus Statin vs. Lifestyle Modification for Preventing ...

Mar 15, 2009 - ...post-menopausal hormone therapy, evidence of hepatic dysfunction, elevated creatine kinase or creatinine levels, diabetes, uncontrolled hypertension, cancer within five years before enrollment, uncontrolled hypothyroidism, any inflammatory or autoimmune condition, recent alcohol or...

American Family Physician : Editorials

https://www.aafp.org/afp/2009/0315/p438.html

The Management of the Acute Migraine Headache - American Family Physician

Dec 1, 2002 - As many as 30 million Americans have migraine headaches. The impact on patients and their families can be tremendous, and treatment of migraines can present diagnostic and therapeutic challenges for family physicians. Abortive treatment options include nonspecific and migraine-specific ...

American Family Physician : Article

https://www.aafp.org/afp/2002/1201/p2123.html

The Pregnant Patient: Managing Common Acute Medical Problems - American Family Physician

Nov 1, 2018 - Women often see their primary care physicians for common acute conditions during pregnancy. These conditions may be caused by pregnancy (obstetric problems) or worsened by pregnancy (obstetrically aggravated problems), or they may require special consideration during pregnancy because ...

American Family Physician : Article

https://www.aafp.org/afp/2018/1101/p595.html

Therapeutic Uses of Magnesium - American Family Physician

Jul 15, 2009 - Magnesium is an essential mineral for optimal metabolic function. Research has shown that the mineral content of magnesium in food sources is declining, and that magnesium depletion has been detected in persons with some chronic diseases. This has led to an increased awareness of proper...

American Family Physician : Article

https://www.aafp.org/afp/2009/0715/p157.html

Therapies for COPD Exacerbations in Adults - Implementing AHRQ Effective Health Care ... Restricted content. Login required.

May 1, 2020 - What are the benefits and harms of pharmacologic and nonpharmacologic treatments for exacerbations of chronic obstructive pulmonary disease (COPD) in adults?

American Family Physician : Implementing AHRQ Effective Health Care Reviews

https://www.aafp.org/afp/2020/0501/p557.html

Tight Control of Type 1 Diabetes: Recommendations for Patients - American Family Physician

Sep 15, 2006 - Tight control of blood glucose levels and risk factors for cardiovascular disease (e.g., hypertension, hypercholesterolemia) can substantially reduce the incidence of microvascular and macrovascular complications from type 1 diabetes. Physicians play an important role in helping ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0915/p971.html

Topical Therapies for Glaucoma: What Family Physicians Need to Know - American Family ...

Apr 1, 1999 - Medication classes historically used in the management of glaucoma include beta blockers, miotics, sympathomimetics and carbonic anhydrase inhibitors. Because topically applied medications are more site specific, they are preferred in the treatment of glaucoma. Compared with oral ...

American Family Physician : Article

https://www.aafp.org/afp/1999/0401/p1871.html

Transient Ischemic Attack: Part II. Risk Factor Modification and Treatment - American ...

Sep 15, 2012 - Interventions following a transient ischemic attack are aimed at preventing a future episode or stroke. Hypertension, current smoking, obesity, physical inactivity, diabetes mellitus, and dyslipidemia are all well-known risk factors, and controlling these factors can have dramatic ...

American Family Physician : Article

https://www.aafp.org/afp/2012/0915/p527.html

Transient Ischemic Attacks: Part II. Treatment - American Family Physician

Apr 1, 2004 - Risk factors for stroke should be evaluated in patients who have had a transient ischemic attack. Blood pressure, lipid levels, and diabetes mellitus should be controlled. When applicable, smoking cessation and weight loss also are important. Angiotensin-converting enzyme inhibitor ...

American Family Physician : Article

https://www.aafp.org/afp/2004/0401/p1681.html

Treating Eating Disorders in Primary Care - American Family Physician

Jan 15, 2008 - Binge-eating disorder, bulimia nervosa, and anorexia nervosa are potentially life-threatening disorders that involve complex psychosocial issues. A strong therapeutic relationship between the physician and patient is necessary for assessing the psychosocial and medical factors used to ...

American Family Physician : Article

https://www.aafp.org/afp/2008/0115/p187.html

Treating Fibromyalgia: Science vs. Art - Editorials - American Family Physician

Oct 1, 2000 - ...of nonpharmacologic therapies. At present, the treatment of fibromyalgia approximates that of hypertension 30 years ago: there were a modest number of marginally effective drugs for hypertension at that time; typically, the patient was told to lose weight and restrict sodium intake....

American Family Physician : Editorials

https://www.aafp.org/afp/2000/1001/p1492.html

Treating Obstructive Sleep Apnea Improves Essential Hypertension and Quality of Life - ...

Jan 15, 2002 - About one half of patients who have essential hypertension have obstructive sleep apnea, and about one half of patients who have obstructive sleep apnea have essential hypertension. A growing body of evidence suggests that obstructive sleep apnea is a major contributing factor in the ...

American Family Physician : Article

https://www.aafp.org/afp/2002/0115/p229.html

Treating Painful Diabetic Peripheral Neuropathy: An Update - American Family Physician

Aug 1, 2016 - Painful diabetic peripheral neuropathy occurs in approximately 25% of patients with diabetes mellitus who are treated in the office setting and significantly affects quality of life. It typically causes burning pain, paresthesias, and numbness in a stocking-glove pattern that progresses...

American Family Physician : Article

https://www.aafp.org/afp/2016/0801/p227.html

Treatment and Prevention of Kidney Stones: An Update - American Family Physician

Dec 1, 2011 - Kidney stones are associated with chronic kidney disease. Preventing recurrence is largely specific to the type of stone (e.g., calcium oxalate, calcium phosphate, cystine, struvite [magnesium ammonium phosphate]), and uric acid stones); however, even when the stone cannot be retrieved,...

American Family Physician : Article

https://www.aafp.org/afp/2011/1201/p1234.html

Treatment of Acute Migraine Headache - American Family Physician

Feb 1, 2011 - Migraine headache is a common and potentially debilitating disorder often treated by family physicians. Before diagnosing migraine, serious intracranial pathology must be ruled out. Treating acute migraine is challenging because of substantial rates of nonresponse to medications and ...

American Family Physician : Article

https://www.aafp.org/afp/2011/0201/p271.html

Treatment of Adult Obesity with Bariatric Surgery - American Family Physician

Jan 1, 2016 - In 2013, approximately 179,000 bariatric surgery procedures were performed in the United States, including the laparoscopic sleeve gastrectomy (42.1%), Roux-en-Y gastric bypass (34.2%), and laparoscopic adjustable gastric banding (14.0%). Choice of procedure depends on the medical ...

American Family Physician : Article

https://www.aafp.org/afp/2016/0101/p31.html

Treatment of Adult Obesity with Bariatric Surgery - American Family Physician

Oct 1, 2011 - Bariatric surgery procedures, including laparoscopic adjustable gastric banding, laparoscopic sleeve gastrectomy, and Roux-en-Y gastric bypass, result in an average weight loss of 50 percent of excess body weight. Remission of diabetes mellitus occurs in approximately 80 percent of ...

American Family Physician : Article

https://www.aafp.org/afp/2011/1001/p805.html

Treatment of Allergic Rhinitis - American Family Physician

Jun 15, 2010 - Allergic rhinitis is a common chronic respiratory illness that affects quality of life, productivity, and other comorbid conditions, including asthma. Treatment should be based on the patient’s age and severity of symptoms. Patients should be advised to avoid known allergens and be ...

American Family Physician : Article

https://www.aafp.org/afp/2010/0615/p1440.html

Treatment of Alzheimer Disease - American Family Physician

Jun 15, 2011 - Alzheimer disease is the most common form of dementia, affecting more than one-third of Americans older than 85 years. It is characterized by progressive memory loss and cognitive decline. Amyloid plaque accumulation, neurofibrillary tau tangles, and depletion of acetylcholine are among...

American Family Physician : Article

https://www.aafp.org/afp/2011/0615/p1403.html

Treatment of Cholesterol Abnormalities - American Family Physician

Mar 15, 2005 - Cardiovascular disease and its subset coronary heart disease are leading causes of morbidity and mortality in the United States and worldwide. In general, higher levels of low-density lipoprotein cholesterol are associated with an increased risk of coronary heart disease, myocardial ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0315/p1137.html

Treatment of Edema - American Family Physician

Jun 1, 2005 - Edema is the result of an imbalance in the filtration system between the capillary and interstitial spaces. The kidneys play a key role in regulating extracellular fluid volume by adjusting sodium and water excretion. Major causes of edema include venous obstruction, increased capillary...

American Family Physician : Article

https://www.aafp.org/afp/2005/0601/p2111.html

Treatment of Ethylene Glycol Poisoning - American Family Physician

Sep 1, 2002 - Ingestion of ethylene glycol may be an important contributor in patients with metabolic acidosis of unknown cause and subsequent renal failure. Expeditious diagnosis and treatment will limit metabolic toxicity and decrease morbidity and mortality. Ethylene glycol poisoning should be ...

American Family Physician : Article

https://www.aafp.org/afp/2002/0901/p807.html

Treatment of Hypertension: Insights from the JNC-VI Report - American Family Physician

Oct 15, 1998 - The sixth report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC-VI) provides updated guidelines for the treatment of hypertension. Antihypertensive drug therapy may be initiated either after a trial of lifestyle ...

American Family Physician : Article

https://www.aafp.org/afp/1998/1015/p1323.html

Treatment of Stable Chronic Obstructive Pulmonary Disease: the GOLD Guidelines - ...

Nov 15, 2013 - Chronic obstructive pulmonary disease (COPD) is a common problem in primary care. COPD is diagnosed with spirometry only in clinically stable patients with a postbronchodilator forced expiratory volume in one second/forced vital capacity ratio of less than 0.70. All patients with COPD ...

American Family Physician : Article

https://www.aafp.org/afp/2013/1115/p655.html

Treatment of Systemic Lupus Erythematosus: An Update - American Family Physician

Jun 1, 1998 - Systemic lupus erythematosus predominantly affects women and is more common in blacks. Although survival rates have improved, over one half of patients with systemic lupus erythematosus have permanent damage in one or more organ systems. Arthritis and cutaneous manifestations are most ...

American Family Physician : Article

https://www.aafp.org/afp/1998/0601/p2753.html

Treatment of the Common Cold - American Family Physician

Feb 15, 2007 - The common cold is a viral illness that affects persons of all ages, prompting frequent use of over-the-counter and prescription medications and alternative remedies. Treatment focuses on relieving symptoms (e.g., cough, nasal congestion, rhinorrhea). Dextromethorphan may be beneficial ...

American Family Physician : Article

https://www.aafp.org/afp/2007/0215/p515.html

Treatment of Threatened Miscarriage with Progestogens - Cochrane for Clinicians - ...

Sep 1, 2019 - Progestogens reduce the risk of miscarriage when compared with placebo in patients with threatened miscarriage (number needed to treat [NNT] = 10.) Use of progestogens poses no significant risks to mother or baby.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0901/p279.html

Treatment of Type 2 Diabetes Mellitus - American Family Physician

May 15, 1999 - Type 2 diabetes mellitus (formerly called non-insulin-dependent diabetes) causes abnormal carbohydrate, lipid and protein metabolism associated with insulin resistance and impaired insulin secretion. Insulin resistance is a major contributor to progression of the disease and to ...

American Family Physician : Article

https://www.aafp.org/afp/1999/0515/p2835.html

Treatment of Type 2 Diabetes Mellitus: A Rational Approach Based on Its Pathophysiology...

May 1, 2001 - ...insulin resistance.1,2 The insulin resistance is associated with a cluster of metabolic abnormalities, including central obesity, hypertension, dyslipidemia (elevated plasma triglycerides, low high-density lipoprotein [HDL] cholesterol levels and postprandial hyperlipidemia),...

American Family Physician : Editorials

https://www.aafp.org/afp/2001/0501/p1687.html

Trigeminal Neuralgia - Clinical Evidence Handbook - American Family Physician

Jul 15, 2016 - What are the effects of ongoing treatments in persons with trigeminal neuralgia?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2016/0715/p133.html

Type 1 Diabetes: Management Strategies - American Family Physician

Aug 1, 2018 - There is considerable benefit of tight glucose control in patients with type 1 diabetes mellitus. Tight blood glucose control dramatically decreases the incidence of microvascular and macrovascular complications. Although glycemic goals should be individualized, most nonpregnant adults ...

American Family Physician : Article

https://www.aafp.org/afp/2018/0801/p154.html

Type 2 Diabetes Mellitus: Outpatient Insulin Management - American Family Physician

Jan 1, 2018 - In patients with type 2 diabetes mellitus, insulin may be used to augment therapy with oral glycemic medications or as insulin replacement therapy. The American Diabetes Association suggests the use of long-acting (basal) insulin to augment therapy with one or two oral agents or one ...

American Family Physician : Article

https://www.aafp.org/afp/2018/0101/p29.html

Type 2 Diabetes: Updated Evidence Requires Updated Decision Making - Editorials - ...

Jul 1, 2015 - Clinicians need to consider the best available research findings, their own experience, and their patients' needs and values.

American Family Physician : Editorials

https://www.aafp.org/afp/2015/0701/p22.html

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