Small Reduction in Cardiovascular Outcome After Ischemic Stroke with Lower LDL Target, ...
Aug 15, 2020 - A lower LDL target slightly reduced the likelihood of a broad composite outcome (number needed to treat [NNT] = 43 over 3.5 years), largely by reducing nonfatal strokes (NNT = 77; statistical significance not reported).
American Family Physician : POEMs
https://www.aafp.org/afp/2020/0815/p247.html
Dapagliflozin (Farxiga) for Preventing Hospitalization for Heart Failure - STEPS - ...
Jul 15, 2020 - Dapagliflozin can be added to existing treatment to reduce the risk of hospitalization for heart failure in patients with type 2 diabetes who have established CVD or are at high risk of CVD. It may also decrease the risk of renal disease progression and death from renal failure.
American Family Physician : STEPS
https://www.aafp.org/afp/2020/0715/p115.html
Bedtime Instead of Morning Ingestion of Hypertension Medication Equals a Significantly ...
Apr 1, 2020 - This study found a significant reduction in mortality and morbidity among patients who took their once-daily anti-hypertensive medications at bedtime instead of in the morning. No significant difference occurred in compliance rates between bedtime and morning ingestion times. Individual...
American Family Physician : POEMs
https://www.aafp.org/afp/2020/0401/p434a.html
Increased Readmissions and Adverse Events with Intensification of Antihypertensive ...
Feb 15, 2020 - The intensification of antihypertensive regimens on discharge in older adults hospitalized for noncardiac conditions is associated with an increased risk of readmission (number needed to harm [NNH] = 27) and medication-related serious adverse events (NNH = 63) within 30 days.
American Family Physician : POEMs
https://www.aafp.org/afp/2020/0215/p248a.html
Managing Chronic Hypertension in Pregnant Women: ACOG Releases Updated Practice ...
Dec 15, 2019 - The American College of Obstetricians and Gynecologists (ACOG) has released an updated practice bulletin to outline diagnosis, effects on pregnancy outcomes, and approaches for management based on new evidence.
American Family Physician : Practice Guidelines
https://www.aafp.org/afp/2019/1215/p782.html
Overuse of Statins in Older Adults - Lown Right Care: Reducing Overuse and Underuse - ...
Dec 15, 2019 - A collaboration between AFP and the Lown Institute promotes a vision of delivering heath care that is based on the evidence, balanced in its approach, and focused on the patient.
American Family Physician : Lown Right Care: Reducing Overuse and Underuse
https://www.aafp.org/afp/2019/1215/p742.html
Early Cardioversion No Better Than Delayed Cardioversion for Recent-Onset Symptomatic ...
Nov 15, 2019 - For patients presenting to the emergency department with recent-onset symptomatic atrial fibrillation, early cardioversion is no better than delayed cardioversion in achieving sinus rhythm within four weeks.
American Family Physician : POEMs
https://www.aafp.org/afp/2019/1115/p648.html
Renin-Angiotensin System Inhibitors vs. Other Antihypertensive Drug Classes for ...
Nov 1, 2019 - RAS inhibitors, which include angiotensin receptor blockers, angiotensin-converting enzyme inhibitors, and renin inhibitors, should not be used as first-line agents.
American Family Physician : Cochrane for Clinicians
https://www.aafp.org/afp/2019/1101/p540.html
Dual Antiplatelet Therapy for Patients with Cardiovascular Disease - FPIN's Clinical ...
Oct 15, 2019 - Patients with established cardiovascular disease or risk factors (e.g., ischemic cerebrovascular disease, peripheral arterial disease, high risk of atherothrombotic disease) should receive dual antiplatelet therapy with aspirin plus clopidogrel, which confers additional benefit over ...
American Family Physician : FPIN's Clinical Inquiries
https://www.aafp.org/afp/2019/1015/p463.html
Antihypertensive Drug Therapy for Mild to Moderate Hypertension During Pregnancy - ...
Oct 1, 2019 - Compared with placebo, antihypertensive drug therapy for mild to moderate hypertension (defined by the authors as a blood pressure of 140 to 169 mm Hg systolic or 90 to 109 mm Hg diastolic) caused by chronic hypertension, gestational hypertension, or preeclampsia during pregnancy does ...
American Family Physician : Cochrane for Clinicians
https://www.aafp.org/afp/2019/1001/p403.html
Effectiveness and Safety of Factor Xa Inhibitors in Patients with Atrial Fibrillation -...
Oct 1, 2019 - Treatment of AFib with a factor Xa inhibitor results in a decrease in the combined end point of stroke and embolic events (odds ratio [OR] = 0.89; 95% CI, 0.82 to 0.97), as well as a decrease in intracranial hemorrhage (OR = 0.50; 95% CI, 0.42 to 0.59) and all-cause mortality (OR = ...
American Family Physician : Cochrane for Clinicians
https://www.aafp.org/afp/2019/1001/p405.html
Overview of New ACC/AHA Lipid Guidelines - POEMs - American Family Physician
Jun 1, 2019 - These updated guidelines, made without any input from primary care physicians who manage most patients with hyperlipidemia, are more complex than the 2013 guidelines and will likely lead to even more recommendations for statins, ezetimibe (Zetia), and PSK9 inhibitors.
American Family Physician : POEMs
https://www.aafp.org/afp/2019/0601/p716.html
Bridging Warfarin Before Colonoscopy in Patients with Atrial Fibrillation - FPIN's ...
Apr 15, 2019 - A limited number of trials that examined the risk of temporary interruption of anticoagulation before a variety of procedures did not find a reduction in the risk of stroke, but they did show an increased risk of bleeding events and venous thromboembolism (VTE) in patients who were ...
American Family Physician : FPIN's Clinical Inquiries
https://www.aafp.org/afp/2019/0415/p519.html
Coaching Patients About Successful Blood Pressure Management - Lown Right Care: ...
Mar 15, 2019 - A collaboration between AFP and the Lown Institute promotes a vision of delivering heath care that is based on the evidence, balanced in its approach, and focused on the patient.
American Family Physician : Lown Right Care: Reducing Overuse and Underuse
https://www.aafp.org/afp/2019/0315/p357.html
Lower Systolic BP During Antihypertensive Treatment Associated with More Deaths in ...
Jan 1, 2019 - In this small cohort study of patients older than 85 years, lower systolic blood pressure during treatment with antihypertensive medications is associated with higher death rates and greater cognitive decline.
American Family Physician : POEMs
https://www.aafp.org/afp/2019/0101/p54.html
Evaluating Benefits and Harms of Anticoagulation in Patients with Atrial Fibrillation -...
Dec 15, 2018 - In patients with NVAF, anticoagulants decrease the risk of stroke by approximately 60%. However, they also significantly increase the risk of a major bleeding event or intracranial hemorrhage.
American Family Physician : Point-of-Care Guides
https://www.aafp.org/afp/2018/1215/p751.html
Blood Pressure Targets for Patients with Hypertension and Cardiovascular Disease - ...
Sep 1, 2018 - Achieving a target BP of 135/85 mm Hg or less does not decrease the risk of total cardiovascular events vs. treating to a target of 140 to 160/90 to 100 mm Hg. Further, treating to the lower BP target does not improve total mortality, cardiovascular mortality, or serious adverse effects.
American Family Physician : Cochrane for Clinicians
https://www.aafp.org/afp/2018/0901/p276.html
Systolic Blood Pressure of At Least 140 mm Hg Best Place to Begin Treatment - POEMs - ...
Aug 15, 2018 - Beginning antihypertensive treatment when the systolic blood pressure is greater than 140 mm Hg delays death and prevents major cardiovascular events in some persons without preexisting heart disease; in patients with existing heart disease, it prevents further events, but does not ...
American Family Physician : POEMs
https://www.aafp.org/afp/2018/0815/p249.html
Stable Coronary Artery Disease: Treatment - American Family Physician
Mar 15, 2018 - Stable coronary artery disease refers to a reversible supply/demand mismatch related to ischemia, a history of myocardial infarction, or the presence of plaque documented by catheterization or computed tomography angiography. Patients are considered stable if they are asymptomatic or ...
American Family Physician : Article
https://www.aafp.org/afp/2018/0315/p376.html
Beta Blockers Compared with Other Drug Options for the Treatment of Hypertension - ...
Feb 1, 2018 - Although beta blockers seem to have a positive impact on patient-oriented evidence that matters in patients with hypertension, they appear to be inferior when compared with other medications.
American Family Physician : Medicine by the Numbers
https://www.aafp.org/afp/2018/0201/od1.html
Nebivolol/Valsartan (Byvalson) for Hypertension - STEPS - American Family Physician
Jan 15, 2018 - Nebivolol/valsartan is an option for the treatment of patients with newly diagnosed or poorly controlled hypertension. Although it offers a new beta-blocker option, no research has demonstrated its benefit over existing treatments.
American Family Physician : STEPS
https://www.aafp.org/afp/2018/0115/p124.html
Intensive Blood Pressure Control in Older Patients Can Decrease Renal Function - POEMs ...
Jan 1, 2018 - In this post-hoc analysis of the previously published SPRINT trial, lowering the systolic blood pressure of patients who are at increased risk of cardiovascular events (average age = 66 years) will decrease their risk of cardiovascular disease but increase their likelihood of developing...
American Family Physician : POEMs
https://www.aafp.org/afp/2018/0101/p54.html
Statin Use for the Primary Prevention of Cardiovascular Disease in Adults - Putting ...
Dec 15, 2017 - L.D., a 66-year-old generally healthy white man, presents for his annual physical. He has no history of cardiovascular disease (CVD); he has had consistent systolic blood pressure measurements of 140 mm Hg; he is not taking any medications; he does not smoke; he exercises three times ...
American Family Physician : Putting Prevention into Practice
https://www.aafp.org/afp/2017/1215/p805.html
Assessing Bleeding Risk in Patients Taking Anticoagulants - Point-of-Care Guides - ...
Oct 1, 2017 - Family physicians are often faced with the dilemma of balancing the benefit of stroke prevention with the risk of major bleeding when deciding on anticoagulation treatment in patients with atrial fibrillation. Over the past 10 years, several decision support tools have been developed ...
American Family Physician : Point-of-Care Guides
https://www.aafp.org/afp/2017/1001/p465.html
Perioperative Cardiovascular Medication Management in Noncardiac Surgery: Common ...
May 15, 2017 - Several medications have been used perioperatively in patients undergoing noncardiac surgery in an attempt to improve outcomes. Antiplatelet therapy for primary prevention of cardiovascular events should generally be discontinued seven to 10 days before surgery to avoid increasing the ...
American Family Physician : Article
https://www.aafp.org/afp/2017/0515/p645.html