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Surgical Treatment for Asymptomatic Cholelithiasis - FPIN's Clinical Inquiries - ...

Mar 15, 2014 - Surgery should not be offered to patients with asymptomatic cholelithiasis. Cholecystectomy may be beneficial for patients who are at high risk of biliary cancer, infection, or other complications, including younger patients and those with choledocholithiasis, sickle cell disease, ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2014/0315/p468.html

Tinnitus - Clinical Evidence Handbook - American Family Physician

Mar 15, 2014 - What are the effects of treatments for chronic tinnitus?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2014/0315/p471.html

Preventing Recurrent Nephrolithiasis in Adults - Implementing AHRQ Effective Health ...

Mar 15, 2014 - What are the potential benefits and adverse effects associated with dietary and pharmacologic interventions to prevent recurrence of kidney stones in adults 18 years and older?

American Family Physician : Implementing AHRQ Effective Health Care Reviews

https://www.aafp.org/afp/2014/0315/p461.html

PPIs, Childhood Asthma, and the Problem of Therapeutic Creep - AFP Journal Club - ...

Mar 15, 2014 - The use of a therapy in patients one would intuitively think might benefit, but in whom no benefit has been documented, is called therapeutic creep. The use of proton pump inhibitors for poorly controlled asthma is an example of this phenomenon.

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2014/0315/p476.html

Impact of Bracing in Adolescents with Idiopathic Scoliosis - POEMs - American Family ...

Mar 15, 2014 - When compared with observation, bracing significantly slows progression of high-risk curves to the surgery threshold (Cobb angle greater than 50 degrees), with a number needed to treat (NNT) of 4 in the randomized portion of the trial. This benefit is greater with more daily hours of ...

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0315/p481.html

AAP Releases Guideline for the Management of Gastroesophageal Reflux in Children - ...

Mar 1, 2014 - The American Academy of Pediatrics (AAP) has published a guideline on the management of gastroesophageal reflux (GER) in children based on recommendations from the North American and European Societies for Pediatric Gastroenterology, Hepatology, and Nutrition. It is important to ...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2014/0301/p395.html

Complex Care: Treating an Older Patient with Multiple Comorbidities - Curbside ...

Mar 1, 2014 - Although there are guidelines for management of single chronic illnesses, the evidence base for management of multiple comorbidities is lacking. The American Geriatrics Society described a clinical approach to managing patients with multiple comorbidities in 2012.

American Family Physician : Curbside Consultation

https://www.aafp.org/afp/2014/0301/p392.html

Long-Term Results of Drug Treatment for Obesity - POEMs - American Family Physician

Mar 1, 2014 - This review of commonly used weight-loss medications, including orlistat (Xenical), lorcaserin (Belviq), phentermine/topiramate (Qsymia), bupropion (Wellbutrin), metformin (Glucophage), and zonisamide (Zonegran), reported an average weight loss for participants of 2.5 to 8.0 kg (5.5 to ...

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0301/p389a.html

Early Developmental Intervention Programs for Preterm Infants - Cochrane for Clinicians...

Mar 1, 2014 - Early intervention programs improve cognitive performance in preterm infants up to 36 months of age, but no effect can be detected by five years of age. A small effect of early intervention on motor performance was found in infancy, but it did not persist until preschool or school age.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/0301/p336.html

Common Questions About Pacemakers - American Family Physician

Feb 15, 2014 - Pacemakers are indicated in patients with certain symptomatic bradyarrhythmias caused by sinus node dysfunction, and in those with frequent, prolonged sinus pauses. Patients with third-degree or complete atrioventricular (AV) block benefit from pacemaker placement, as do those with type...

American Family Physician : Article

https://www.aafp.org/afp/2014/0215/p279.html

Roflumilast (Daliresp) for Chronic Obstructive Pulmonary Disease - STEPS - American ...

Feb 15, 2014 - Roflumilast therapy has a limited role in patients with severe COPD, and no role in patients with mild to moderate COPD. It will not decrease the number of hospitalizations.

American Family Physician : STEPS

https://www.aafp.org/afp/2014/0215/p300.html

Lending a Hand to Patients with Type 2 Diabetes: A Simple Way to Communicate Treatment ...

Feb 15, 2014 - A new approach to the care of adults with type 2 diabetes emphasizes proven interventions that improve duration and quality of life.

American Family Physician : Editorials

https://www.aafp.org/afp/2014/0215/p256.html

Fish Oil for Treatment of Dyslipidemia - FPIN's Clinical Inquiries - American Family ...

Feb 15, 2014 - Supplementation with omega-3 fatty acids decreases triglyceride and very low-density lipoprotein cholesterol levels. However, it can also increase low-density lipoprotein (LDL) cholesterol levels. Treatment with omega-3 fatty acids does not decrease total mortality, cardiovascular ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2014/0215/p288.html

Amoxicillin/Clavulanate or Ibuprofen No Better Than Placebo for Acute Bronchitis - ...

Feb 1, 2014 - Treating acute bronchitis with amoxicillin/clavulanate or the nonsteroidal anti-inflammatory drug ibuprofen is no more effective than placebo in decreasing symptoms in general or duration of frequent cough. Treatment does, however, produce adverse effects in one in eight patients.

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0201/p225.html

Aspirin With or Without Antiemetic for Acute Migraine Headaches in Adults - Cochrane ...

Feb 1, 2014 - Aspirin, with or without an antiemetic, is an effective treatment for acute migraine headache. Adding the antiemetic metoclopramide (Reglan) significantly reduces migraine-related nausea and vomiting compared with aspirin alone.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/0201/p176.html

Colchicine Effective for First Episode of Acute Pericarditis - POEMs - American Family ...

Feb 1, 2014 - When used in addition to conventional anti-inflammatory therapy, colchicine decreases the rate of incessant or recurrent pericarditis. You would need to treat four patients with colchicine to prevent one such episode.

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0201/p226.html

Methylphenidate for Management of Fatigue in the Palliative Care Setting - FPIN's ...

Jan 15, 2014 - No recent evidence demonstrates that methylphenidate improves fatigue in patients receiving palliative care. Methylphenidate can be used to minimally improve fatigue symptom scores in patients with cancer-related fatigue.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2014/0115/p124.html

Dementia - Clinical Evidence Handbook - American Family Physician

Jan 15, 2014 - What are the effects of treatments on cognitive, behavioral, and psychological symptoms of dementia (Alzheimer disease, Lewy body dementia, or vascular dementia)?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2014/0115/p117.html

Is Intensive Blood Pressure Control Beneficial in Patients with Acute Intracerebral ...

Jan 15, 2014 - It seems to be safe to lower systolic blood pressure to a target of 140 mm Hg in those with an acute hemorrhagic stroke. However, there seems to be no clinical benefit to this approach when the data are adjusted for baseline NIH Stroke Scale scores.

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2014/0115/p120.html

Pioglitazone Exposure Increases Bladder Cancer Risk - POEMs - American Family Physician

Jan 15, 2014 - This review of all available data found a significantly increased risk of bladder cancer among adults with type 2 diabetes treated with pioglitazone. Pioglitazone also significantly increases the risk of heart failure, and there is minimal, if any, patient-oriented evidence of benefit ...

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0115/p136.html

Role of Breathing Exercises in the Treatment of COPD - Cochrane for Clinicians - ...

Jan 1, 2014 - Patients with COPD who are treated with breathing exercises vs. standard care showed an improvement in exercise capacity, with inconsistent changes in dyspnea and health-related quality of life. Adding breathing exercises to a pulmonary rehabilitation program did not show any increased ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/0101/p15.html

Corticosteroids for the Treatment of Sore Throat - Cochrane for Clinicians - American ...

Jan 1, 2014 - In adults with suspected bacterial pharyngitis who require antibiotic therapy, adding a corticosteroid may increase the likelihood of complete pain resolution at 24 hours. Further study is needed to assess the safety of corticosteroids and whether they can be recommended for presumed ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/0101/p14.html

Clopidogrel Plus 21 Days of Aspirin Is Superior to Aspirin Alone Within First 24 Hours ...

Jan 1, 2014 - Patients with minor stroke (National Institutes of Health [NIH] Stroke Scale score ≤ 3) or TIA have a decreased risk of recurrent stroke if given aspirin plus clopidogrel vs. aspirin alone if started within 24 hours of the onset of symptoms. There was no significant increase in the risk...

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0101/p55.html

Palliative Care: Benefits, Barriers, and Best Practices - Editorials - American Family ...

Dec 15, 2013 - Palliative care improves the quality of life for patients with a life-threatening illness and for their families. Despite documented benefits, palliative care is underutilized in the management of advanced or terminal illnesses.

American Family Physician : Editorials

https://www.aafp.org/afp/2013/1215/p807.html

Ticagrelor (Brilinta) for Secondary Prevention of Thrombotic Events Following Acute ...

Dec 15, 2013 - Ticagrelor is an alternative to clopidogrel for secondary prevention of cardiovascular death in patients with acute coronary syndrome. In an international study it was found to be more effective, but patients in the United States did not experience superior outcomes.

American Family Physician : STEPS

https://www.aafp.org/afp/2013/1215/p821.html

Intensive Lifestyle Intervention Fails to Improve Patient-Oriented Outcomes in Persons ...

Dec 15, 2013 - This large, well-designed trial failed to find a statistically significant improvement in patient-oriented outcomes in patients with diabetes, despite a fairly intensive lifestyle intervention and long-term follow-up.

American Family Physician : POEMs

https://www.aafp.org/afp/2013/1215/od1.html

Exercise Effective for Depression in Older Patients - POEMs - American Family Physician

Dec 15, 2013 - An organized exercise program for older patients, which may include strength training, endurance training, or both, may be helpful for some patients with symptoms of depression. The results will not be striking, but exercise is an option for patients willing to participate.

American Family Physician : POEMs

https://www.aafp.org/afp/2013/1215/od2.html

Treatments for Symptoms of the Common Cold - FPIN's Clinical Inquiries - American ...

Dec 15, 2013 - There is no single treatment that produces significant improvements in symptoms of the common cold. Intranasal ipratropium (Atrovent) can be given to reduce rhinorrhea. Oral zinc can be given therapeutically to shorten cold duration and severity, and can be taken prophylactically to ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2013/1215/od3.html

Common Questions About Vasectomy - American Family Physician

Dec 1, 2013 - Vasectomy offers a safe, effective, and permanent method of male contraception, with an overall failure rate of less than 1% in pooled studies. Men older than 30 years in a stable, committed relationship appear to be the best candidates for vasectomy. The no-scalpel technique reduces ...

American Family Physician : Article

https://www.aafp.org/afp/2013/1201/p757.html

Five-Day Steroid Treatment Effective for Acute COPD Exacerbation - POEMs - American ...

Dec 1, 2013 - A five-day course of systemic glucocorticoids is at least as effective as a 14-day course in the treatment of adults with acute exacerbations of COPD.

American Family Physician : POEMs

https://www.aafp.org/afp/2013/1201/od1.html

Are Cranberry Products Effective for the Prevention of Urinary Tract Infections? - ...

Dec 1, 2013 - Cranberry products are not effective and should not be recommended for the prevention of UTIs.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/1201/p745.html

Skip the Strict Salt and Fluid Restriction for Hospitalized Patients with Heart Failure...

Dec 1, 2013 - This study suggests that a low-sodium and fluid-restricted diet, compared with a non-restricted diet, for patients hospitalized with acute decompensated heart failure does not expedite weight loss or decrease congestion. Patients placed on such diets are, as expected, significantly ...

American Family Physician : POEMs

https://www.aafp.org/afp/2013/1201/od2.html

Aspirin Is as Safe and Effective as LMWH for Extended Thromboprophylaxis After Total ...

Dec 1, 2013 - Aspirin is as effective as dalteparin for extended thromboprophylaxis in patients who had total hip arthroplasty and had initially received 10 days of dalteparin prophylaxis postoperatively. Because of its relative safety, low cost, and easy administration, aspirin is an attractive ...

American Family Physician : POEMs

https://www.aafp.org/afp/2013/1201/p739.html

Vitamin D Does Not Affect Isolated Systolic Hypertension - POEMs - American Family ...

Dec 1, 2013 - Vitamin D supplementation in patients with isolated systolic hypertension and low levels of vitamin D does not decrease systolic blood pressure after one year of treatment.

American Family Physician : POEMs

https://www.aafp.org/afp/2013/1201/p739a.html

Finasteride Prevents Low-Grade Prostate Cancers, but Does Not Reduce Mortality - POEMs ...

Dec 1, 2013 - Although finasteride prevents low-grade prostate tumors, it does not affect overall survival or survival after prostate cancer diagnosis. Although high-grade cancers were more common among men taking finasteride, up to 18 years of follow-up failed to show increased mortality in this group.

American Family Physician : POEMs

https://www.aafp.org/afp/2013/1201/p744.html

Treatment of Stable Chronic Obstructive Pulmonary Disease: the GOLD Guidelines - ...

Nov 15, 2013 - Chronic obstructive pulmonary disease (COPD) is a common problem in primary care. COPD is diagnosed with spirometry only in clinically stable patients with a postbronchodilator forced expiratory volume in one second/forced vital capacity ratio of less than 0.70. All patients with COPD ...

American Family Physician : Article

https://www.aafp.org/afp/2013/1115/p655.html

Chronic Suppurative Otitis Media - Clinical Evidence Handbook - American Family Physician

Nov 15, 2013 - What are the effects of treatments for chronic suppurative otitis media in adults and children? What are the effects of treatments for cholesteatoma in adults and children?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2013/1115/p694.html

Second-Generation Antidepressants for Depression in Adults - Implementing AHRQ ...

Nov 15, 2013 - What are the comparative effectiveness and adverse effects of second-generation antidepressants for treating depression in adults?

American Family Physician : Implementing AHRQ Effective Health Care Reviews

https://www.aafp.org/afp/2013/1115/p687.html

AAP Releases Guideline on Managing Type 2 Diabetes Mellitus in Patients 10 to 18 Years ...

Nov 15, 2013 - Childhood type 2 diabetes poses a challenge to many physicians who are not used to treating this disease in such young patients. The American Academy of Pediatrics (AAP) has released a guideline of evidence-based recommendations for treating type 2 diabetes in patients 10 to 18 years of...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2013/1115/p710.html

Risks of Bisphosphonate Use - FPIN's Clinical Inquiries - American Family Physician

Nov 15, 2013 - Bisphosphonates are associated with a small risk of atypical femoral shaft fractures, which increases with duration of use. Bisphosphonates are associated with a small risk of osteonecrosis of the jaw, which is more common in patients who are older, female, or have poor dental hygiene ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2013/1115/p697.html

Choosing the Right Inhaled Medication Device for COPD - Editorials - American Family ...

Nov 15, 2013 - Data suggest that inhaler devices have similar effectiveness in treating patients with COPD; however, a variety of factors must be considered when selecting the best device for each patient.

American Family Physician : Editorials

https://www.aafp.org/afp/2013/1115/p650.html

Myocardial Infarction: Management of the Subacute Period - American Family Physician

Nov 1, 2013 - Optimal management of myocardial infarction in the subacute period focuses on improving the discharge planning process, implementing therapies early to prevent recurrent myocardial infarction, and avoiding hospital readmission. Evidence-based guidelines for the care of patients with ...

American Family Physician : Article

https://www.aafp.org/afp/2013/1101/p581.html

Outpatient Management of Alcohol Withdrawal Syndrome - American Family Physician

Nov 1, 2013 - Approximately 2% to 9% of patients seen in a family physician’s office have alcohol dependence. These patients are at risk of developing alcohol withdrawal syndrome if they abruptly abstain from alcohol use. Alcohol withdrawal syndrome begins six to 24 hours after the last intake of ...

American Family Physician : Article

https://www.aafp.org/afp/2013/1101/p589.html

Management of Stable Ischemic Heart Disease: Recommendations from the ACP - Practice ...

Nov 1, 2013 - The American College of Physicians (ACP) has developed a guideline on the management of stable ischemic heart disease (IHD). This summary presents recommendations related to risk factor modification (including strategies of unproven benefit), medical therapies to prevent myocardial ...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2013/1101/p612.html

Optimal Antibiotic Regimen for Treating Lower UTI in Children - Cochrane for Clinicians...

Nov 1, 2013 - For the afebrile child with a UTI, a short course (three to seven days) of antibiotics is as effective at preventing the recurrence of symptomatic UTI as a long course (seven to 10 days). There is no clear evidence of superiority for any one antibiotic regimen.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/1101/p577.html

After Detoxification: Levels of Treatment for Alcohol Dependence - Editorials - ...

Nov 1, 2013 - Detoxification is just the tip of the iceberg, and the postdischarge treatment program is key in determining whether patients will abstain from alcohol.

American Family Physician : Editorials

https://www.aafp.org/afp/2013/1101/p576.html

Low-Dose Penicillin Prevents Recurrent Cellulitis - POEMs - American Family Physician

Nov 1, 2013 - For patients with at least two previous episodes of cellulitis in the previous three years, low-dose penicillin can prevent recurrence (number needed to treat = 6).

American Family Physician : POEMs

https://www.aafp.org/afp/2013/1101/p608a.html

Dextrose Prolotherapy Decreases Pain and Stiffness in Knee Degenerative Joint Disease -...

Nov 1, 2013 - Dextrose prolotherapy appears to be more effective in decreasing pain and stiffness, and improving function in patients with knee degenerative joint disease than saline injections and home exercise.

American Family Physician : POEMs

https://www.aafp.org/afp/2013/1101/od1.html

Breast Cancer Prevented in Some Women with Drug Treatment - POEMs - American Family ...

Nov 1, 2013 - In some postmenopausal women at higher-than-average risk of breast cancer, tamoxifen and, to a lesser extent, raloxifene (Evista) will prevent the development of breast cancer. For every 1,000 women who receive the prophylaxis, there will be seven to nine fewer cases of diagnosed breast...

American Family Physician : POEMs

https://www.aafp.org/afp/2013/1101/p608.html

Sexual, Urinary, and Bowel Dysfunction Common After Treatment for Localized Prostate ...

Nov 1, 2013 - Patients undergoing surgery had worse urinary and sexual outcomes, whereas those undergoing external beam radiation therapy (EBRT) had worse bowel symptoms. Watchful waiting (active surveillance) was not the subject of this study, but given the problems associated with therapy, active ...

American Family Physician : POEMs

https://www.aafp.org/afp/2013/1101/p609.html

Ultrasound-Guided Steroid Injections for Shoulder Pain - Cochrane for Clinicians - ...

Oct 1, 2013 - Ultrasound-guided glucocorticoid injection for shoulder pain provides no advantage over landmark-guided or intramuscular injection in terms of pain, function, range of motion, or safety when measured within a six-week follow-up period. However, the small sample size of this review means...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/1001/p433.html

Should Children with Acute Otitis Media Routinely be Treated with Antibiotics? No: Most...

Oct 1, 2013 - The evidence supports the use of antibiotics only in certain clinical situations and avoidance of antibiotics in certain children with AOM.

American Family Physician : Editorials: Controversies in Family Medicine

https://www.aafp.org/afp/2013/1001/od2.html

Should Children with Acute Otitis Media Routinely Be Treated with Antibiotics? Yes: ...

Oct 1, 2013 - The demonstrated benefits of antibiotic use are an average of one less day of pain and fever, which is about evenly offset by the risk of adverse effects. Benefits warrant discussion with parents for shared decision making regarding treatment.

American Family Physician : Editorials: Controversies in Family Medicine

https://www.aafp.org/afp/2013/1001/od1.html

Tubal Ectopic Pregnancy - Clinical Evidence Handbook - American Family Physician

Oct 1, 2013 - What treatments improve outcomes in women with unruptured tubal ectopic pregnancy?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2013/1001/p459.html

ACR Publishes Guidelines for Pharmacologic and Nonpharmacologic Treatment of Gout - ...

Sep 15, 2013 - The American College of Rheumatology (ACR) has developed recommendations for the management of gout. The recommendations call for a systematic nonpharmacologic and pharmacologic management approach that is intended to be applicable to all patients with gout.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2013/0915/p408.html

Management of ADHD in Preschool-Aged Children - FPIN's Clinical Inquiries - American ...

Sep 15, 2013 - Behavior therapy interventions, such as parent training, are first-line treatment for ADHD in preschool-aged children (three to five years of age). Medication is an option for children with moderate to severe ADHD if behavior therapy has not been effective and if the benefits outweigh ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2013/0915/p398.html

IDSA Updates Guideline for Managing Group A Streptococcal Pharyngitis - Practice ...

Sep 1, 2013 - The Infectious Diseases Society of America (IDSA) has updated its 2002 guideline on managing group A streptococcal pharyngitis. The illness primarily occurs in children five to 15 years of age. Patients typically present with sudden onset of a sore throat, pain with swallowing, and fever.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2013/0901/p338.html

Minocycline for Acne Vulgaris - Cochrane for Clinicians - American Family Physician

Sep 1, 2013 - Compared with placebo, minocycline generally improves acne, but it offers no clinical advantages over other therapies and has more serious adverse effects.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/0901/p300.html

Risks Associated with Long-Term Benzodiazepine Use - Editorials - American Family ...

Aug 15, 2013 - Many patients underestimate the degree of impairment caused by benzodiazepines. Benzodiazepines increase the risk of addiction, withdrawal, cognitive decline, motor vehicle crashes, and hip fracture. The risk of overdose is particularly great when combined with sedative drugs such as ...

American Family Physician : Editorials

https://www.aafp.org/afp/2013/0815/p224.html

Vilazodone (Viibryd) for the Treatment of Depression - STEPS - American Family Physician

Aug 15, 2013 - The available evidence does not support the routine use of vilazodone in the treatment of depression. It is significantly more expensive than generic alternatives and is no more effective for moderate to severe depression than selective serotonin reuptake inhibitors or tricyclic ...

American Family Physician : STEPS

https://www.aafp.org/afp/2013/0815/p263.html

Interventions for Lower-Extremity Lymphedema - FPIN's Clinical Inquiries - American ...

Aug 15, 2013 - Complete decongestive physiotherapy (i.e., a noninvasive protocol consisting of skin care, lymph drainage massage, exercises, and compression bandaging1) effectively improves edema, rates of infection, and quality of life in patients with lower-extremity lymphedema.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2013/0815/od1.html

ADHD Interventions in Children Younger Than Six Years - Implementing AHRQ Effective ...

Aug 15, 2013 - What are the potential benefits and adverse effects associated with treatments for attention-deficit/hyperactivity disorder (ADHD) in preschool-aged children (younger than six years)?

American Family Physician : Implementing AHRQ Effective Health Care Reviews

https://www.aafp.org/afp/2013/0815/p266.html

Acute Asthma and Other Recurrent Wheezing Disorders in Children - Clinical Evidence ...

Jul 15, 2013 - What are the effects of treatments for acute asthma in children?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2013/0715/p130.html

Endocrine Society Releases Guidelines on Diagnosis and Management of ...

Jul 15, 2013 - The Endocrine Society recently published evidence-based recommendations on the diagnosis and management of hypertriglyceridemia in adults. Contributing factors include overweight and obesity, physical inactivity, excessive alcohol intake, metabolic syndrome, type 2 diabetes mellitus, ...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2013/0715/p142.html

Treating Patients with Borderline Personality Disorder in the Medical Office - Curbside...

Jul 15, 2013 - The prevalence of borderline personality disorder in the general population is thought to be between 1% and 2%. As family physicians, we often treat these patients for chronic medical conditions. There are multiple obstacles to caring for these patients because of their difficult ...

American Family Physician : Curbside Consultation

https://www.aafp.org/afp/2013/0715/p140.html

Corticosteroids for Presumed Pneumocystis Pneumonia in Patients with HIV Infection - ...

Jul 15, 2013 - Adjunctive corticosteroids decrease mortality in patients with HIV infection who have moderate to severe hypoxemia and suspected or confirmed pneumocystis pneumonia. Corticosteroids lead to a higher incidence of herpetic lesions, but not other opportunistic conditions.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2013/0715/od1.html

Pharmacotherapy for Mild Hypertension - Cochrane for Clinicians - American Family ...

Jul 1, 2013 - Pharmacologic treatment of mild hypertension for up to five years does not reduce coronary events, stroke, or mortality compared with placebo.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/0701/p21.html

Gynecologic Procedures: Colposcopy, Treatments of Cervical Intraepithelial Neoplasia, ...

Jun 15, 2013 - Women who have abnormal Papanicolaou test results may undergo colposcopy to determine the biopsy site for histologic evaluation. Traditional grading systems do not accurately assess lesion severity because colposcopic impression alone is unreliable for diagnosis. The likelihood of ...

American Family Physician : Article

https://www.aafp.org/afp/2013/0615/p836.html

Spinosad (Natroba) for Head Lice - STEPS - American Family Physician

Jun 15, 2013 - Spinosad is safe and effective for the treatment of head lice; most patients will be lice-free after a single treatment. Nit combing following treatment is not necessary. These benefits must be weighed against its prescription-only status and higher cost compared with nonprescription ...

American Family Physician : STEPS

https://www.aafp.org/afp/2013/0615/p874.html

Pharmacologic Therapy for Eustachian Tube Dysfunction - FPIN's Clinical Inquiries - ...

Jun 15, 2013 - There are no medications that improve patient-oriented outcomes in children or adults with eustachian tube dysfunction. Oral corticosteroids, with or without antibiotics, improve pneumatic otoscopy and tympanometry findings in the short term, but these agents have no long-term benefit.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2013/0615/p883.html

Is Rivaroxaban Noninferior to Standard Warfarin Therapy in Preventing Recurrent PE and ...

Jun 15, 2013 - A trial showing that one drug is noninferior to another does not mean that these drugs are equivalent. The noninferiority margin allows researchers to choose their own benchmark for what is considered a clinically significant difference between two drugs.

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2013/0615/p872.html

Pharmacologic Therapy for Acute Pain - American Family Physician

Jun 1, 2013 - The approach to patients with acute pain begins by identifying the underlying cause and a disease-specific treatment. The first-line pharmacologic agent for the symptomatic treatment of mild to moderate pain is acetaminophen or a nonsteroidal anti-inflammatory drug (NSAID). The choice ...

American Family Physician : Article

https://www.aafp.org/afp/2013/0601/p766.html

Contraceptive Education for Women After Childbirth - Cochrane for Clinicians - American...

Jun 1, 2013 - Postpartum education may increase contraceptive use and reduce unplanned repeat pregnancies, although the evidence is mixed. The optimal timing and content of educational programs are not known.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/0601/p761.html

Oxytocin Augmentation During Labor with Epidural Analgesia - Cochrane for Clinicians - ...

Jun 1, 2013 - Oxytocin augmentation does not reduce the frequency of cesarean delivery, instrumental vaginal delivery, or the combined outcome of both. Oxytocin also has no effect on low five-minute Apgar scores, postpartum hemorrhage, uterine hyperstimulation, or neonatal intensive care unit ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/0601/p760.html

Multiple Sclerosis - Clinical Evidence Handbook - American Family Physician

May 15, 2013 - What are the effects of interventions aimed at reducing relapse rates and disability and to improve symptoms during acute relapse in persons with multiple sclerosis? What are the effects of treatments for fatigue and spasticity in persons with multiple sclerosis? What are the effects of...

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2013/0515/p712.html

Bromocriptine Mesylate (Cycloset) for Type 2 Diabetes Mellitus - STEPS - American ...

May 15, 2013 - Cycloset will lower A1C levels by 0.3 to 0.5 percent when taken alone or in combination with a sulfonylurea, without undesirable adverse effects such as hypoglycemia and weight gain. It will not cause further improvement of glucose control when used with insulin, metformin, or other ...

American Family Physician : STEPS

https://www.aafp.org/afp/2013/0515/p718.html

Treatments for Urinary Incontinence in Women - Implementing AHRQ Effective Health Care ...

May 15, 2013 - What are the effectiveness, benefits, and adverse effects of options for diagnosis and treatment of urinary incontinence (UI) that are available in primary care?

American Family Physician : Implementing AHRQ Effective Health Care Reviews

https://www.aafp.org/afp/2013/0515/p726.html

Clinical Management of Urinary Incontinence in Women - American Family Physician

May 1, 2013 - Most cases of urinary incontinence in women fall under one of three major subtypes: urge, stress, or mixed. A stepped-care approach that advances from least invasive (behavioral modification) to more invasive (surgery) interventions is recommended. Bladder retraining and pelvic floor ...

American Family Physician : Article

https://www.aafp.org/afp/2013/0501/p634.html

Updated Guidelines on Outpatient Anticoagulation - American Family Physician

Apr 15, 2013 - The American College of Chest Physicians provides recommendations for the use of anticoagulant medications for several indications that are important in the primary care setting. Warfarin, a vitamin K antagonist, is recommended for the treatment of venous thromboembolism and for the ...

American Family Physician : Article

https://www.aafp.org/afp/2013/0415/p556.html

Diabetes: Treating Hypertension - Clinical Evidence Handbook - American Family Physician

Apr 15, 2013 - What are the effects of antihypertensives and different blood pressure targets in persons with diabetes and hypertension?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2013/0415/p574.html

Metformin Use in Adolescents - FPIN's Clinical Inquiries - American Family Physician

Apr 15, 2013 - There are no studies evaluating whether metformin prevents or delays the onset of diabetes in adolescents who are obese. In adults, metformin is as effective as lifestyle interventions in preventing increases in A1C and fasting glucose levels, but it is less effective in preventing or ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2013/0415/od4.html

Management of Chronic Tendon Injuries - American Family Physician

Apr 1, 2013 - Chronic tendon injuries present unique management challenges. The assumption that these injuries result from ongoing inflammation has caused physicians to rely on treatments demonstrated to be ineffective in the long term. Nonsteroidal anti-inflammatory drugs should be limited in the ...

American Family Physician : Article

https://www.aafp.org/afp/2013/0401/p486.html

ACR Issues Recommendations on Therapies for Osteoarthritis of the Hand, Hip, and Knee -...

Apr 1, 2013 - The American College of Rheumatology (ACR) has released updated recommendations for the treatment of osteoarthritis of the hip and knee, and has developed new recommendations for the treatment of osteoarthritis of the hand. These recommendations are categorized as strong or conditional.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2013/0401/p515.html

Effect of Cocoa on Blood Pressure - Cochrane for Clinicians - American Family Physician

Apr 1, 2013 - Consuming 50 g of cocoa daily will lower blood pressure 2 to 3 mm Hg on average in adults with hypertension. Evidence of improved patient-oriented outcomes does not exist.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/0401/p484.html

Appropriate Use of Polypharmacy for Older Patients - Cochrane for Clinicians - American...

Apr 1, 2013 - Multidisciplinary interventions that address polypharmacy decrease inappropriate prescribing and medication-related problems in patients 65 years and older, but it is not clear if they reduce hospital admissions or improve quality of life. Most interventions studied were led by ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/0401/p483.html

Kidney Stones - Clinical Evidence Handbook - American Family Physician

Mar 15, 2013 - What are the effects of interventions for the removal of asymptomatic renal or ureteric stones? What are the effects of interventions for the management of acute renal colic?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2013/0315/p441.html

Diabetic Ketoacidosis: Evaluation and Treatment - American Family Physician

Mar 1, 2013 - Diabetic ketoacidosis is characterized by a serum glucose level greater than 250 mg per dL, a pH less than 7.3, a serum bicarbonate level less than 18 mEq per L, an elevated serum ketone level, and dehydration. Insulin deficiency is the main precipitating factor. Diabetic ketoacidosis ...

American Family Physician : Article

https://www.aafp.org/afp/2013/0301/p337.html

Caring for Older Patients Who Have Significant Hearing Loss - Curbside Consultation - ...

Mar 1, 2013 - This scenario illustrates issues related to end-of-life care and placement in a long-term care facility for older individuals with significant hearing loss. An analysis of data from the 1999 to 2006 cycles of the National Health and Nutrition Examination Survey, and statistics from the ...

American Family Physician : Curbside Consultation

https://www.aafp.org/afp/2013/0301/p360.html

Analgesics for Osteoarthritis - Implementing AHRQ Effective Health Care Reviews - ...

Mar 1, 2013 - What are the comparative effectiveness, benefits, and adverse effects of oral and topical analgesics for osteoarthritis?

American Family Physician : Implementing AHRQ Effective Health Care Reviews

https://www.aafp.org/afp/2013/0301/p354.html

Physical Training for Patients with Asthma - Cochrane for Clinicians - American Family ...

Mar 1, 2013 - Physical training lasting for at least 20 to 30 minutes, two to three times a week for at least six weeks, improves physical fitness in patients with asthma. Physical training is not associated with worsening of asthma symptoms, and it improves health-related quality of life.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/0301/p313.html

Pharmacologic Therapy for Vitamin D Deficiency - FPIN's Clinical Inquiries - American ...

Feb 15, 2013 - Cholecalciferol (vitamin D3) supplementation should be used for vitamin D repletion because it may be more effective in preventing nonvertebral fractures.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2013/0215/od2.html

AASM Updates Treatment Guidelines for Restless Legs Syndrome and Periodic Limb Movement...

Feb 15, 2013 - The American Academy of Sleep Medicine (AASM) last published recommendations on the treatment of restless legs syndrome (RLS) and periodic limb movement disorder in 2004. It recently updated these recommendations based on a literature review and meta-analysis.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2013/0215/p290.html

Primary Insomnia in Older Persons - Clinical Evidence Handbook - American Family Physician

Feb 15, 2013 - What are the effects of nondrug and drug treatments for primary insomnia in older persons (those 60 years and older)?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2013/0215/p280.html

Fidaxomicin (Dificid) for Clostridium difficile Infection - STEPS - American Family ...

Feb 1, 2013 - Fidaxomicin is effective for the treatment of C. difficile infection, but it is much more expensive than traditional therapy. Until it is known that the benefits outweigh the significant cost, metronidazole or oral vancomycin is the preferred treatment for most patients.

American Family Physician : STEPS

https://www.aafp.org/afp/2013/0201/p211.html

Generalized Anxiety Disorder - Clinical Evidence Handbook - American Family Physician

Jan 15, 2013 - What are the effects of treatments for generalized anxiety disorder in adults and children and adolescents?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2013/0115/p122.html

ACP Updates Guideline on Oral Pharmacologic Treatments for Type 2 Diabetes Mellitus - ...

Jan 15, 2013 - The American College of Physicians (ACP) has published an updated guideline on the oral pharmacologic management of type 2 diabetes. Recommendations are based on a systematic evidence review of head-to-head comparisons of oral pharmacologic treatments for type 2 diabetes, and an ...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2013/0115/p140.html

Caffeine as an Analgesic Adjuvant for Acute Pain in Adults - Cochrane for Clinicians - ...

Jan 1, 2013 - Overall, there appears to be a small but clinically significant benefit to adding caffeine to analgesic therapy for various types of acute pain. More research is needed to determine the optimal dosing.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/0101/p11.html

Cutaneous Cryosurgery - American Family Physician

Dec 15, 2012 - Cutaneous cryosurgery refers to localized application of freezing temperatures to achieve destruction of skin lesions. It can be used to treat a broad range of benign and premalignant skin conditions, and certain malignant skin conditions, with high cure rates. Cellular destruction is ...

American Family Physician : Article

https://www.aafp.org/afp/2012/1215/p1118.html

Linagliptin (Tradjenta) for the Treatment of Diabetes Mellitus - STEPS - American ...

Dec 15, 2012 - Linagliptin reduces A1C levels to a lesser extent than first-line therapy (metformin) and is significantly more expensive than metformin and sulfonylureas. Importantly, its ability to affect diabetes-related morbidity and mortality is not known.

American Family Physician : STEPS

https://www.aafp.org/afp/2012/1215/p1144.html

Should the Target A1C Level Be Less Than 7 Percent? No: The Case for Modest Glycemic ...

Dec 15, 2012 - No: The Case for Modest Glycemic Control in Patients with Type 2 Diabetes

American Family Physician : Editorials: Controversies in Family Medicine

https://www.aafp.org/afp/2012/1215/od2.html

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