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Aripiprazole vs. Placebo or Haloperidol for Schizophrenia - Medicine by the Numbers - ...

Dec 1, 2016 - Aripiprazole was shown to have one major benefit over placebo, but favorable outcomes with haloperidol throw its effectiveness into question. Are the differences merely anomalies?

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2016/1201/p877.html

Managing Opioid Addiction with Buprenorphine - American Family Physician

May 1, 2006 - Legislation has enabled physicians to treat opioid-dependent patients with an office-based maintenance program using buprenorphine, a partial mu-opioid receptor agonist. Clinical studies indicate buprenorphine effectively manages opioid addiction. Buprenorphine is more effective than ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0501/p1573.html

Promoting Medication Adherence in Children - American Family Physician

Sep 1, 2006 - The problem of getting children to follow a treatment regimen is widespread and is frustrating for physicians. The extent to which any patient adheres to a medical regimen is an essential determinant of clinical success. Strategies to improve adherence in children include using ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0901/p793.html

Impact of Exercise-Based Cardiac Rehabilitation - Cochrane for Clinicians - American ...

Dec 1, 2016 - Exercise-based cardiac rehabilitation reduces cardiovascular mortality and hospitalization. There is no evidence that it reduces the rates of total mortality, myocardial infarctions, coronary artery bypass grafts, or percutaneous coronary interventions.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2016/1201/p881.html

Interventions to Improve Antibiotic Prescribing for Uncomplicated Acute RTIs - ...

Dec 1, 2016 - What are the effectiveness and adverse consequences of strategies for reducing antibiotic use in adults and children with uncomplicated acute respiratory tract infections (RTIs)?

American Family Physician : Implementing AHRQ Effective Health Care Reviews

https://www.aafp.org/afp/2016/1201/p918.html

Lumbar Fusion No Better Than Exercise and Therapy in the Long Term - POEMs - American ...

Dec 1, 2016 - This trial is a good example of how to do just about everything wrong to get the results you want. The authors did not conceal allocation, did not mask anyone in the study, used an unvalidated and subjective primary outcome, and downplayed the intention-to-treat analysis. Funding for ...

American Family Physician : POEMs

https://www.aafp.org/afp/2016/1201/p937.html

Amiodarone for the Prevention of Sudden Cardiac Death - Cochrane for Clinicians - ...

Nov 1, 2016 - Although not a substitute for an implantable cardioverter-defibrillator (ICD), amiodarone is effective for the primary prevention of sudden cardiac death when compared with placebo (number needed to treat [NNT] = 47; 95% confidence interval [CI], 33 to 100), but it does not ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2016/1101/p692.html

Vasectomy: An Update - American Family Physician

Dec 15, 2006 - Vasectomy remains an important option for contraception. Research findings have clarified many questions regarding patient selection, optimal technique, postsurgical follow-up, and risk of long-term complications. Men who receive vasectomies tend to be non-Hispanic whites, well ...

American Family Physician : Article

https://www.aafp.org/afp/2006/1215/p2069.html

Primary Care for Patients with HIV Infection: It’s Not Who Should Provide It, It’s How ...

Nov 1, 2016 - The major challenge is not to address whether primary care clinicians without substantial HIV experience should provide HIV care, but to create a framework that allows all primary care clinicians to provide the best possible care for their patients living with HIV infection.

American Family Physician : Editorials

https://www.aafp.org/afp/2016/1101/p687.html

Croup - Clinical Evidence Handbook - American Family Physician

Sep 15, 2016 - What are the effects of treatments (dexamethasone or humidification) in children with mild and moderate to severe croup?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2016/0915/p476.html

Honey for Acute Cough in Children - Cochrane for Clinicians - American Family Physician

Jul 1, 2016 - For patients one to 18 years of age, providing honey for cough symptoms can reduce the frequency and severity of cough, as well as improve sleep for patients and parents, when compared with placebo or no treatment. Honey is no better than dextromethorphan for symptom control.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2016/0701/p20.html

How to Prescribe Fewer Unnecessary Antibiotics: Talking Points That Work with Patients ...

Aug 1, 2016 - Appropriate antibiotic prescribing is a quality-of-care issue; all clinicians have the responsibility to provide the right treatments to their patients while minimizing harm. Effective communication, public commitments, and delayed antibiotic prescriptions are evidence-based tools ...

American Family Physician : Editorials

https://www.aafp.org/afp/2016/0801/p200.html

Suvorexant (Belsomra) for Insomnia - STEPS - American Family Physician

Jun 15, 2016 - Suvorexant effectively increases total sleep time and decreases time to sleep onset. Because of its risk of abuse, significant incidence of next-day impairment, and high cost, it should be reserved for use in patients for whom other insomnia therapies, such as cognitive behavior therapy...

American Family Physician : STEPS

https://www.aafp.org/afp/2016/0615/p1016.html

Selective Serotonin Reuptake Inhibitors for Fibromyalgia - Cochrane for Clinicians - ...

Oct 1, 2016 - SSRIs may have a small to moderate effect on pain (number needed to treat [NNT] = 10), global improvement (NNT = 7), and depression (NNT = 13) in patients with fibromyalgia, but the quality of evidence is very low because of bias and small studies. SSRIs do not reduce fatigue related to...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2016/1001/p548.html

Procalcitonin Guidance Safely Decreases Antibiotic Use in Critically Ill Patients - ...

Oct 15, 2016 - For patients in the intensive care unit (ICU) who receive antibiotics for presumed or proven bacterial infections, the use of procalcitonin levels to determine when to stop antibiotic therapy results in decreased duration and consumption of antibiotics without increasing mortality.

American Family Physician : POEMs

https://www.aafp.org/afp/2016/1015/p663a.html

Single-Dose Dexamethasone Equals Three Days of Steroids in Children with Acute Asthma -...

Aug 15, 2016 - In addition to usual beta-agonist treatment, a single dose of oral dexamethasone is as effective as three days of prednisolone (with less vomiting) in decreasing respiratory symptoms without increasing hospitalizations, follow-up visits, and days lost from school. Additional treatment ...

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0815/p317.html

All Analgesics Are Better Than Placebo in Patients with Knee or Hip DJD - POEMs - ...

Oct 15, 2016 - In patients with hip or knee DJD, all analgesics are more effective than placebo in relieving pain and improving function. Although paracetamol (acetaminophen) is the least effective of all the drugs studied, it still may be the first treatment for these patients because of its safety ...

American Family Physician : POEMs

https://www.aafp.org/afp/2016/1015/p664.html

Management of Active Tuberculosis - American Family Physician

Dec 1, 2005 - Although the overall incidence of tuberculosis has been declining in the United States, it remains an important public health concern, particularly among immigrants, homeless persons, and persons infected with human immunodeficiency virus. Patients who present with symptoms of active ...

American Family Physician : Article

https://www.aafp.org/afp/2005/1201/p2225.html

A Family Physicians' Guide to Monitoring Methotrexate - American Family Physician

Oct 1, 2000 - Methotrexate has a long history of use in the treatment of various immunologic diseases, including rheumatoid arthritis and psoriasis. Although the drug is usually prescribed by a subspecialist, a family physician may assume responsibility for monitoring methotrexate therapy. Major ...

American Family Physician : Article

https://www.aafp.org/afp/2000/1001/p1607.html

Knee Surgery Does Not Reduce Knee Catching or Locking in Patients with Meniscal Tear - ...

Aug 15, 2016 - Removing the torn bits of meniscus in middle-aged patients who have intermittent knee catches or locking does not decrease their likelihood of experiencing symptoms in the following year compared with diagnostic arthroscopy (i.e., looking but not touching). In general, meniscectomy does...

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0815/p317a.html

Rivaroxaban vs. Warfarin for Anticoagulation in Patients with Atrial Fibrillation ...

Oct 1, 2016 - Studies showed that 433 patients needed to be treated with rivaroxaban to prevent one stroke and 629 patients needed to be treated with rivaroxaban to prevent one thromboembolic event. Read more.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2016/1001/od1.html

Alternatives to Metformin for Patients with PCOS - FPIN's Help Desk Answers - American ...

Sep 1, 2016 - Compared with placebo, thiazolidinediones (TZDs) decrease systolic blood pressure and fasting blood glucose and insulin levels while improving menstrual irregularities in women with PCOS. Metformin and TZDs have similar effects on pregnancy rates, ovulation, and menstrual frequency, but...

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2016/0901/p378.html

Alirocumab (Praluent) for Treatment of Hyperlipidemia - STEPS - American Family Physician

Aug 15, 2016 - Alirocumab is a novel lipid-lowering therapy that is highly effective at lowering LDL cholesterol when used in addition to statin therapy and diet. Its use should be limited to patients with either heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular ...

American Family Physician : STEPS

https://www.aafp.org/afp/2016/0815/p310.html

Inhaled Fluticasone-Salmeterol Better Than Fluticasone Alone for Moderate to Severe ...

Sep 1, 2016 - The combination of fluticasone and salmeterol (Advair), with the steroid dose adjusted for disease severity, reduces the number of severe asthma exacerbations more than fluticasone (Flovent) alone (number needed to treat [NNT] = 50 over 26 weeks), with no difference in terms of ...

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0901/p387.html

Rural Opioid Use Disorder Treatment Depends on Family Physicians - Graham Center Policy...

Oct 1, 2016 - The nation's growing opioid use disorder epidemic disproportionately impacts rural areas, where physicians who can prescribe buprenorphine are scarcest. Among physicians approved to prescribe buprenorphine, family physicians (FPs) are the most likely to work in rural areas.

American Family Physician : Graham Center Policy One-Pagers

https://www.aafp.org/afp/2016/1001/p546.html

Appendicitis - Clinical Evidence Handbook - American Family Physician

Jan 15, 2016 - What are the effects of surgery compared with antibiotics for acute appendicitis?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2016/0115/p142.html

Acetaminophen for the Treatment of Pain in Newborns - Cochrane for Clinicians - ...

Aug 1, 2016 - Acetaminophen does not significantly reduce pain associated with heel lance, eye examinations, or assisted vaginal births in newborns. Acetaminophen may reduce the total amount of morphine a newborn needs in the first 48 hours following major abdominal or thoracic surgery.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2016/0801/p216.html

Management of Head and Neck Injuries by the Sideline Physician - American Family Physician

Oct 15, 2006 - Injuries to the head and neck are common in sports. Sideline physicians must be attentive and prepared with an organized approach to detect and manage these injuries. Because head and neck injuries often occur simultaneously, the sideline physician can combine the head and neck ...

American Family Physician : Article

https://www.aafp.org/afp/2006/1015/p1357.html

Management of Cluster Headache - American Family Physician

Feb 15, 2005 - Cluster headache, an excruciating, unilateral headache usually accompanied by conjunctival injection and lacrimation, can occur episodically or chronically, and can be difficult to treat. Existing effective treatments may be underused because of underdiagnosis of the syndrome. Oxygen ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0215/p717.html

Capsaicin for Nonallergic Rhinitis - Cochrane for Clinicians - American Family Physician

Aug 1, 2016 - Intranasal capsaicin is safe and effective for reducing symptoms of nonallergic rhinitis (number needed to treat = 4; 95% confidence interval [CI], 1 to 22). There is insufficient evidence to compare the effectiveness of capsaicin to other topical or systemic medications.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2016/0801/p217.html

Medical Management of Common Urinary Calculi - American Family Physician

Jul 1, 2006 - Nephrolithiasis is a common condition affecting nearly 5 percent of U.S. men and women during their lifetimes. Recurrent calculi can be prevented in most patients by the use of a simplified evaluation, reasonable dietary and fluid recommendations, and directed pharmacologic ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0701/p86.html

Dysmenorrhea - American Family Physician

Jan 15, 2005 - Dysmenorrhea is the leading cause of recurrent short-term school absence in adolescent girls and a common problem in women of reproductive age. Risk factors for dysmenorrhea include nulliparity, heavy menstrual flow, smoking, and depression. Empiric therapy can be initiated based on a ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0115/p285.html

Intermittent Inhaled Corticosteroid Therapy for Mild Persistent Asthma in Children and ...

Jul 1, 2016 - Intermittent inhaled corticosteroid therapy reduces the risk of asthma exacerbations in children and adults with mild persistent asthma. Intermittent use appears to be safe in these patients.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2016/0701/p21.html

Opportunities to Improve Outcomes in Sickle Cell Disease - American Family Physician

Jul 15, 2006 - Sickle cell disease represents a spectrum of inherited hemoglobin disorders. The pathophysiology involves abnormalities not just in red blood cells but also vascular endothelium, white blood cell function, coagulation, and inflammatory response. Known sequelae of sickle cell disease ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0715/p303.html

CBT Effective in Adolescents with Depression Who Do Not Want Medication - POEMs - ...

Sep 1, 2016 - In adolescents who eschew drug treatment of major depression, short-term CBT is more effective than treatment as usual in inducing recovery, with a number needed to treat of 4 to 10. CBT also produced faster results.

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0901/p384.html

Methadone Treatment for Pain States - American Family Physician

Apr 1, 2005 - Methadone is a synthetic opioid with potent analgesic effects. Although it is associated commonly with the treatment of opioid addiction, it may be prescribed by licensed family physicians for analgesia. Methadone's unique pharmacokinetics and pharmacodynamics make it a valuable option ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0401/p1353.html

Family Medicine: An Underutilized Resource in Addressing the Opioid Epidemic? - Graham ...

Sep 1, 2016 - Opioid overdose rates have tripled since 2000, and although overprescribing of opioids by physicians is widely accepted as a causal factor, the physician's role in providing medication-assisted treatment for opioid use disorder is less appreciated. Despite a clear willingness to ...

American Family Physician : Graham Center Policy One-Pagers

https://www.aafp.org/afp/2016/0901/p350.html

Flibanserin Ineffective for Hypoactive Sexual Desire Disorder in Women - POEMs - ...

Sep 1, 2016 - Flibanserin produces a minimal effect on sexual desire and minimally increases the number of satisfying sexual events in women (less than one-half an event per month increase). Many women will be unable to tolerate the adverse effects.

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0901/p384a.html

Newer Sulfonylureas Not Associated with Increased Mortality, MIs, or Strokes - POEMs - ...

Sep 1, 2016 - In multiple randomized trials, the long-term use of second- or third-generation sulfonylureas in patients with type 2 diabetes is not associated with more deaths, myocardial infarctions (MIs), or strokes. The included trials tended not to report other safety data.

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0901/p386.html

Pharmacotherapy for Adults with Alcohol Use Disorder - Implementing AHRQ Effective ...

Jul 15, 2016 - What are the potential benefits and adverse effects of medications used to treat alcohol use disorder (AUD) in adult outpatients?

American Family Physician : Implementing AHRQ Effective Health Care Reviews

https://www.aafp.org/afp/2016/0715/p155.html

AHA/ACC/ASH Release Guideline on the Treatment of Hypertension and CAD - Practice ...

Dec 1, 2015 - The American Heart Association (AHA), American College of Cardiology (ACC), and American Society of Hypertension (ASH) have released a guideline on the management of hypertension in patients with coronary artery disease (CAD). It updates a previous AHA guideline to reflect newer data.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2015/1201/p1023.html

Topical NSAIDs for Acute Musculoskeletal Pain in Adults - Medicine by the Numbers - ...

Jul 1, 2016 - Studies show that patients had improved pain control with diclofenac gel, ketoprofen gel, and ibuprofen gel with no increase in local or systemic adverse events. See why.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2016/0701/od1.html

Pioglitazone After Stroke or TIA Reduces Stroke and MI, but Also Has Significant Harms ...

Aug 15, 2016 - In patients with a recent stroke or TIA and evidence of insulin resistance, pioglitazone reduces the likelihood of myocardial infarction (MI) or stroke (number needed to treat [NNT] = 36 over five years) but increases the risk of significant weight gain (number needed to treat to harm ...

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0815/p319.html

Stop Using Antipsychotics to Treat or Prevent Delirium—They Are No Better Than Placebo ...

Aug 15, 2016 - The available data indicate that antipsychotic medications are ineffective in preventing or treating delirium in hospitalized patients. Because there are concerns about falls and extrapyramidal effects with antipsychotics (not reported in this study), we should stop using them.

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0815/p318.html

Exercise to Improve Functioning in Patients with Dementia - FPIN's Help Desk Answers - ...

Aug 1, 2016 - Exercise programs lasting at least two months moderately increase the ability of patients with dementia to perform ADLs.

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2016/0801/p242.html

Quinine for Leg Cramps - Cochrane for Clinicians - American Family Physician

Feb 1, 2016 - Quinine is moderately effective in decreasing the frequency and intensity of muscle cramps, but it is also associated with an increase in minor adverse effects. In addition, there is a risk of rare but serious adverse effects.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2016/0201/p177.html

Acupuncture for Frequent Tension-Type Headaches - Medicine by the Numbers - American ...

Aug 1, 2016 - Studies show an NNT of 3 to have at least a 50% reduction of headache frequency compared with routine care. Want to know more?

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2016/0801/od1.html

CDC Develops Guideline for Opioid Prescribing - Practice Guidelines - American Family ...

Jun 15, 2016 - A recently released guideline aims to establish patient-centered approaches to initiating, managing, and discontinuing opioid use. The recommendations from the Centers for Disease Control and Prevention (CDC) emphasize the serious risks and harms associated with opioids.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2016/0615/p1042.html

Omega-3 Fatty Acids - American Family Physician

Jul 1, 2004 - Omega-3 fatty acids have been shown to significantly reduce the risk for sudden death caused by cardiac arrhythmias and all-cause mortality in patients with known coronary heart disease. Fatty fish, such as salmon and tuna, and fish oil are rich sources of the omega-3 fatty acids ...

American Family Physician : Article

https://www.aafp.org/afp/2004/0701/p133.html

Nutritional Assessment and Counseling for Prevention and Treatment of Cardiovascular ...

Jan 15, 2006 - Physicians face several barriers to counseling their patients about nutrition, including conflicting evidence of the benefit of counseling, limited training and understanding of the topic, and imperfect and varied guidelines to follow. Because cardiovascular disease remains the leading ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0115/p257.html

Curbing Inappropriate Antibiotic Prescribing: What Works? - Editorials - American ...

Aug 1, 2016 - The reasons for antibiotic overprescribing are multifactorial, so efforts to reduce inappropriate antibiotic prescribing should combine shared decision making, incentives, quality-control measures, and similar interventions designed to improve clinical practice.

American Family Physician : Editorials

https://www.aafp.org/afp/2016/0801/p203.html

ACCP Releases Guideline for the Treatment of Unexplained Chronic Cough - Practice ...

Jun 1, 2016 - Persistent cough with an unknown etiology is difficult to treat and can significantly affect quality of life. Although the evidence for the diagnosis and treatment of adults with unexplained chronic cough is limited, the American College of Chest Physicians (ACCP) has released ...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2016/0601/p950.html

Coenzyme Q10 - American Family Physician

Sep 15, 2005 - Coenzyme Q10 is a vitamin-like substance used in the treatment of a variety of disorders primarily related to suboptimal cellular energy metabolism and oxidative injury. Studies supporting the efficacy of coenzyme Q10 appear most promising for neurodegenerative disorders such as ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0915/p1065.html

Vascular Surgery: An Update - American Family Physician

Jan 1, 2007 - Caring for patients with vascular illnesses has become increasingly more complex and has changed dramatically over the past 10 years, with a widening array of diagnostic and treatment options. Carotid artery stenting has the potential to become a viable alternative to open surgery in ...

American Family Physician : Article

https://www.aafp.org/afp/2007/0101/p85.html

Caring for Patients with Job Insecurity Who Are Experiencing Chronic Work-Related Pain ...

Jul 15, 2016 - In addition to providing direct medical care, the physician can help this patient by obtaining an occupational history, formulating hypotheses about the cause of the pain and potential interventions, and establishing a therapeutic relationship.

American Family Physician : Curbside Consultation

https://www.aafp.org/afp/2016/0715/p145.html

The Importance of Beta Blockers in the Treatment of Heart Failure - American Family ...

Dec 1, 2000 - Heart failure, the only cardiovascular disease with an increasing incidence, is associated with significant mortality and poses a considerable economic burden. Traditionally, beta blockers have been considered to be contraindicated in patients with heart failure. Recently, however, ...

American Family Physician : Article

https://www.aafp.org/afp/2000/1201/p2453.html

Alpha-Lipoic Acid for Treatment of Diabetic Peripheral Neuropathy - FPIN's Help Desk ...

May 1, 2016 - Intravenous (IV) ALA can improve neuropathy symptoms when administered for three weeks, but symptom improvement with oral ALA is not clinically significant. There is no evidence evaluating long-term treatment.

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2016/0501/p786.html

Treatments for Sciatica - FPIN's Clinical Inquiries - American Family Physician

May 1, 2015 - Surgical diskectomy can be offered to patients with refractory sciatica, but there is only modest, short-term improvement in leg pain and disability scores. Epidural steroid injections may be offered to patients with sciatica of more than six months' duration.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2015/0501/p612.html

Blood Pressure Goal of 140 to 150 mm Hg Is Best for Patients with Diabetes - POEMs - ...

Jul 1, 2016 - Although most recent practice guidelines have relaxed the blood pressure goals for patients with diabetes, there are still a few holdouts that suggest aggressive treatment. This analysis shows that the ideal range for hypertension control in patients with diabetes is between 140 and 150...

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0701/p59a.html

No Reduction in Readmissions with Telemonitoring, Coaching for Patients with Heart ...

Jul 15, 2016 - A care transition intervention that incorporates remote monitoring of weight, blood pressure, and heart rate with scheduled telephone coaching did not reduce readmission rates at 30 days or 180 days for patients with heart failure. However, patients in the study were only modestly ...

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0715/p168a.html

Herpes Zoster and Postherpetic Neuralgia: Prevention and Management - American Family ...

Sep 15, 2005 - The recognizable appearance and the dermatomal distribution of herpes zoster lesions usually enable a clinical diagnosis to be made easily. Herpes zoster and postherpetic neuralgia occur mainly in older patients. The role of the varicella vaccine in preventing herpes zoster is ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0915/p1075.html

Management of Grapefruit-Drug Interactions - American Family Physician

Aug 15, 2006 - Grapefruit is a healthy addition to a well-balanced diet. However, the fruit has been shown to affect the metabolism of many medications, increasing the risk of toxicity and adverse effects. Characteristics of oral medications that may interact with grapefruit include extensive ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0815/p605.html

Mediterranean Diet Produces Moderate Weight Loss - POEMs - American Family Physician

Jul 1, 2016 - In addition to improving cardiovascular outlook, a Mediterranean diet produced greater sustained weight loss than a low-fat diet and similar weight loss to other diets in patients who were overweight or obese, most of whom had type 2 diabetes mellitus.

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0701/p59.html

Ivabradine (Corlanor) for Heart Failure - STEPS - American Family Physician

Apr 15, 2016 - In patients with stable systolic heart failure already on maximal medication therapy, adding ivabradine may reduce the number of hospitalizations related to heart failure (NNT for two years = 20), but it does not reduce cardiovascular mortality. In addition, many patients will not ...

American Family Physician : STEPS

https://www.aafp.org/afp/2016/0415/p682.html

Chronic Suppurative Otitis Media - Clinical Evidence Handbook - American Family Physician

Nov 15, 2013 - What are the effects of treatments for chronic suppurative otitis media in adults and children? What are the effects of treatments for cholesteatoma in adults and children?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2013/1115/p694.html

Oral Analgesics for Acute Nonspecific Pain - American Family Physician

Mar 1, 2005 - Physicians most often recommend or prescribe oral medication for relief of acute pain. This review of the available evidence supports the use of acetaminophen in doses up to 1,000 mg as the initial choice for mild to moderate acute pain. In some cases, modest improvements in analgesic ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0301/p913.html

Tight Control of Type 1 Diabetes: Recommendations for Patients - American Family Physician

Sep 15, 2006 - Tight control of blood glucose levels and risk factors for cardiovascular disease (e.g., hypertension, hypercholesterolemia) can substantially reduce the incidence of microvascular and macrovascular complications from type 1 diabetes. Physicians play an important role in helping ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0915/p971.html

Using the CDC Guideline and Tools for Opioid Prescribing in Patients with Chronic Pain ...

Jun 15, 2016 - The new CDC guideline is intended to help clinicians decide whether and how to prescribe opioids for chronic pain; offer safer, more effective care for patients with chronic pain; improve clinician-patient communication; and prevent opioid use disorder and opioid-related overdose.

American Family Physician : Editorials

https://www.aafp.org/afp/2016/0615/p970.html

Tamsulosin Effective as Expulsion Therapy for 5- to 10-mm Distal Ureteric Stones - ...

May 1, 2016 - Tamsulosin promotes stone passage of ureteric stones that are 5 to 10 mm. Five patients would need to be treated with tamsulosin to cause the expulsion of one such stone. Stones smaller than 5 mm have a high rate of spontaneous passage without any intervention.

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0501/p788a.html

The Opioid Epidemic: AMA’s response - Editorials - American Family Physician

Jun 15, 2016 - With Lembke article and opioid PG

American Family Physician : Editorials

https://www.aafp.org/afp/2016/0615/p975.html

Common Overuse Tendon Problems: A Review and Recommendations for Treatment - American ...

Sep 1, 2005 - There is a common misconception that symptomatic tendon injuries are inflammatory; because of this, these injuries often are mislabeled as tendonitis. Acute inflammatory tendinopathies exist, but most patients seen in primary care will have chronic symptoms suggesting a degenerative ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0901/p811.html

Behavioral and Pharmacotherapy Interventions for Tobacco Smoking Cessation in Adults, ...

May 15, 2016 - A 40-year-old woman presents for a routine antepartum visit. She is 20 weeks pregnant and smokes half a pack of cigarettes per day despite efforts to quit. She has no other concerns, and her physical examination findings are normal. The patient asks if your clinic offers services to ...

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2016/0515/p861.html

Breast Pain - Clinical Evidence Handbook - American Family Physician

May 15, 2016 - What are the effects of treatments for breast pain?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2016/0515/p872.html

Levonorgestrel-Releasing Intrauterine System vs. Oral Progestins for Treatment of ...

Jun 1, 2016 - The levonorgestrel-releasing intrauterine system achieves significantly higher resolution rates of endometrial hyperplasia without atypia compared with cyclic oral progestins (68% to 100% vs. 48% to 69%, respectively).

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2016/0601/p948.html

Childhood Asthma: Treatment Update - American Family Physician

May 15, 2005 - The prevalence of childhood asthma has risen significantly over the past four decades. A family history of atopic disease is associated with an increased likelihood of developing asthma, and environmental triggers such as tobacco smoke significantly increase the severity of daily asthma...

American Family Physician : Article

https://www.aafp.org/afp/2005/0515/p1959.html

Behavioral Interventions Reduce Inappropriate Antibiotic Prescribing for Acute ...

Jun 15, 2016 - Requiring clinicians to justify antibiotic prescribing in the permanent electronic health record and to undergo periodic peer comparisons of prescribing rates are effective interventions for reducing inappropriate antibiotic prescribing for acute respiratory tract infections. Helpful ...

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0615/p1037.html

Chondroitin/Glucosamine Equal to Celecoxib for Knee Osteoarthritis - POEMs - American ...

Jun 15, 2016 - or patients with painful knee osteoarthritis, a high-dose combination of glucosamine hydrochloride (1,500 mg) and chondroitin (1,200 mg) was as effective in lessening pain and stiffness and improving function as celecoxib (200 mg). Other studies have not found benefit.

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0615/p1032.html

Meta-Analysis: Intensive BP Control Decreases Major CV Events and Stroke, but Not MI, ...

Jun 15, 2016 - Patients with hypertension who are treated intensively are less likely to have major cardiovascular events, stroke, or progression of albuminuria or retinopathy than those treated less intensively, but intensive lowering had no meaningful effect on myocardial infarctions, heart failure,...

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0615/p1036.html

Management of Dyslipidemia in Adults - American Family Physician

May 1, 1998 - The importance of treating dyslipidemias based on cardiovascular risk factors is highlighted by the National Cholesterol Education Program guidelines. The first step in evaluation is to exclude secondary causes of hyperlipidemia. Assessment of the patient's risk for coronary heart ...

American Family Physician : Article

https://www.aafp.org/afp/1998/0501/p2192.html

Corticosteroids for Community-Acquired Pneumonia - Medicine by the Numbers - American ...

Jun 1, 2016 - Studies show that 1 in 20 patients avoided mechanical ventilation and 1 in 16 patients avoided ARDS; 1 in 29 patients developed hyperglycemia requiring treatment. Read more.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2016/0601/od1.html

Flibanserin (Addyi) for Hypoactive Sexual Desire Disorder in Premenopausal Women - ...

May 15, 2016 - Although flibanserin results in a modest improvement in the number of satisfying sexual events (approximately one more per month vs. placebo), it does not improve other measures, is considerably expensive, and has significant adverse effects.

American Family Physician : STEPS

https://www.aafp.org/afp/2016/0515/p826.html

Antiviral Therapy for Bell Palsy - Cochrane for Clinicians - American Family Physician

May 1, 2016 - The combination of antiviral agents and corticosteroids is more effective than corticosteroids alone for the complete recovery of patients with Bell palsy (number needed to treat [NNT] = 15) and for the resolution of motor synkinesis and excessive tear production (NNT = 12). Antivirals ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2016/0501/p742.html

Using ACE Inhibitors Appropriately - American Family Physician

Aug 1, 2002 - When first introduced in 1981, angiotensin-converting enzyme (ACE) inhibitors were indicated only for treatment of refractory hypertension. Since then, they have been shown to reduce morbidity or mortality in congestive heart failure, myocardial infarction, diabetes mellitus, chronic ...

American Family Physician : Article

https://www.aafp.org/afp/2002/0801/p461.html

CDC Releases 2015 Guidelines on the Treatment of Sexually Transmitted Disease - ...

Jan 15, 2016 - The Centers for Disease Control and Prevention has updated its 2010 recommendations to help guide physicians in preventing and treating sexually transmitted diseases. This summary practice guideline will focus on the updates.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2016/0115/p144.html

Management of Crohn's Disease--A Practical Approach - American Family Physician

Aug 15, 2003 - Crohn's disease is a chronic inflammatory disorder of the gastrointestinal tract that affects up to 480,000 persons in the United States. Symptoms include abdominal pain, diarrhea, fever, malaise, and arthralgias, and cause considerable morbidity. Speculation about genetic, ...

American Family Physician : Article

https://www.aafp.org/afp/2003/0815/p707.html

Magnesium Sulfate for Prevention of Preterm Birth - Cochrane for Clinicians - American ...

Apr 1, 2015 - Magnesium sulfate does not delay delivery when used in patients with preterm labor. Although magnesium sulfate is not associated with any serious adverse maternal outcomes, it may be associated with an increase in total fetal, neonatal, and infant mortality.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2015/0401/p444.html

Antidepressants for the Treatment of Insomnia in Patients with Depression - FPIN's ...

Nov 1, 2011 - There is no single antidepressant or class of antidepressants that is most effective for the treatment of insomnia in patients with depression. The use of antidepressant medications can have a positive impact on sleep physiology, but does not seem to improve subjective ratings of sleep ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2011/1101/od1.html

Conjugated Estrogens/Bazedoxifene (Duavee) for Menopausal Symptoms - STEPS - American ...

Feb 15, 2016 - Conjugated estrogens/bazedoxifene is effective for the treatment of menopausal symptoms and may be better tolerated than conjugated estrogens/medroxyprogesterone. It will maintain bone mineral density in the lumbar spine and hip, but its effect on fractures is not known. Cardiovascular ...

American Family Physician : STEPS

https://www.aafp.org/afp/2016/0215/p307.html

Diagnostic and Therapeutic Injection of the Hip and Knee - American Family Physician

May 15, 2003 - Joint injection of the hip and knee regions is a useful diagnostic and therapeutic tool for the family physician. In this article, the injection procedure for the greater trochanteric bursa, the knee joint, the pes anserine bursa, the iliotibial band, and the prepatellar bursa is ...

American Family Physician : Article

https://www.aafp.org/afp/2003/0515/p2147.html

Ibuprofen for Treatment of Episodic Tension-Type Headaches - Medicine by the Numbers - ...

May 1, 2016 - Studies show that 1 in 14 patients were parin-free at two hours and none experienced adverse events. Find out more.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2016/0501/od1.html

Palliative Care: Benefits, Barriers, and Best Practices - Editorials - American Family ...

Dec 15, 2013 - Palliative care improves the quality of life for patients with a life-threatening illness and for their families. Despite documented benefits, palliative care is underutilized in the management of advanced or terminal illnesses.

American Family Physician : Editorials

https://www.aafp.org/afp/2013/1215/p807.html

ACE Inhibitors vs. ARBs for Primary Hypertension - Cochrane for Clinicians - American ...

Apr 15, 2015 - ACE inhibitors and ARBs have similar effects on cardiovascular outcomes and total mortality in head-to-head trials. However, slightly more adverse effects were noted in patients assigned to ACE inhibitor therapy.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2015/0415/p522.html

The Impact of Contraception on Lactation - Cochrane for Clinicians - American Family ...

Mar 1, 2016 - Use of hormonal contraception does not appear to shorten breastfeeding duration or negatively impact infant growth, based on inconsistent evidence of moderate quality. It is unclear if hormonal contraception negatively impacts breast milk volume or composition. Overall, there was ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2016/0301/p356.html

Naproxen Alone May Be Best for Acute Low Back Pain - POEMs - American Family Physician

Feb 15, 2016 - Naproxen alone is as effective as naproxen plus oxycodone/acetaminophen or naproxen plus cyclobenzaprine (Flexeril) in reducing pain and improving function in adults with acute musculoskeletal LBP without radicular symptoms. Adverse events were significantly more common in patients ...

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0215/p316.html

Long-Acting Nitrates No Good for Heart Failure with Preserved Ejection Fraction - POEMs...

May 1, 2016 - Patients who have heart failure with preserved ejection fraction had decreased levels of activity and more adverse events when they were receiving isosorbide mononitrate than when they were taking a placebo. Moreover, activity levels decreased with increases in the dose of the drug, ...

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0501/p790.html

Diagnostic and Therapeutic Injection of the Ankle and Foot - American Family Physician

Oct 1, 2003 - Joint and soft tissue injection of the ankle and foot region is a useful diagnostic and therapeutic tool for the family physician. This article reviews the injection procedure for the plantar fascia, ankle joint, tarsal tunnel, interdigital space, and first metatarsophalangeal joint. ...

American Family Physician : Article

https://www.aafp.org/afp/2003/1001/p1356.html

Transitional Care Interventions to Prevent Readmissions for Patients with Heart Failure...

Mar 1, 2016 - Home visiting programs and multidisciplinary clinic interventions for adult patients with heart failure reduced all-cause readmissions and mortality over three to six months. Structured telephone support reduced heart failure–specific readmissions and mortality over three to six months....

American Family Physician : Implementing AHRQ Effective Health Care Reviews

https://www.aafp.org/afp/2016/0301/p401.html

Delayed Prescription for Respiratory Infections Produces Similar Results and ...

May 1, 2016 - In almost 400 Spanish primary care patients with mild to moderate symptoms of respiratory infection of less than one week's duration, both a take-and-hold prescription and a come back and pick up, if necessary prescription produced a similar clinical response—and similar patient ...

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0501/p789.html

Clinically Significant Drug Interactions - American Family Physician

Mar 15, 2000 - A large number of drugs are introduced every year, and new interactions between medications are increasingly reported. Consequently, it is no longer practical for physicians to rely on memory alone to avoid potential drug interactions. Multiple drug regimens carry the risk of adverse ...

American Family Physician : Article

https://www.aafp.org/afp/2000/0315/p1745.html

Nonpharmaceutical Treatment of Anxiety in Institutionalized Older Adults - FPIN's Help ...

Apr 1, 2016 - Cognitive behavior therapy (CBT) or relaxation training, alone or in combination, can be used to treat anxiety in older adults. Music therapy can also be used to reduce anxiety in older adults. Appropriate training of institutional caregivers is also helpful in reducing anxiety in older...

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2016/0401/p592.html

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