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Newer Intranasal Migraine Medications - American Family Physician

Jan 1, 2000 - Two new intranasal migraine medications, sumatriptan and dihydroergotamine mesylate, may offer specific advantages for patients who are seeking alternatives to various oral or parenteral migraine abortive therapies. Placebo-controlled clinical studies demonstrate that both intranasal ...

American Family Physician : Article

https://www.aafp.org/afp/2000/0101/p180.html

Newer Oral Hypoglycemics Do Not Increase or Decrease Mortality - POEMs - American ...

Oct 15, 2017 - This seems like a strange question considering that the goal is to decrease mortality with drug therapy. Nevertheless, this study showed that the new kids on the diabetes block—exenatide (Byetta), dulaglutide (Trulicity), sitagliptin (Januvia), saxagliptin (Onglyza), and others—do not ...

American Family Physician : POEMs

https://www.aafp.org/afp/2017/1015/od2.html

Newer Pharmacologic Alternatives for Erectile Dysfunction - American Family Physician

Sep 15, 1999 - With the introduction of effective pharmacologic therapies for erectile dysfunction, more men are seeking treatment. The underlying cause of erectile dysfunction is usually a chronic medical illness or a side effect of certain drugs. Less commonly, the problem is psychogenic. Even after...

American Family Physician : Article

https://www.aafp.org/afp/1999/0915/p1159.html

Newer Sulfonylureas Not Associated with Increased Mortality, MIs, or Strokes - POEMs - ...

Sep 1, 2016 - In multiple randomized trials, the long-term use of second- or third-generation sulfonylureas in patients with type 2 diabetes is not associated with more deaths, myocardial infarctions (MIs), or strokes. The included trials tended not to report other safety data.

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0901/p386.html

Newly Detected Atrial Fibrillation: AAFP Updates Guideline on Pharmacologic Management ...

Sep 1, 2017 - The American Academy of Family Physicians, with the American College of Physicians, has updated its 2003 guideline to provide guidance on atrial fibrillation treatment via medication in the primary care setting. The guideline focuses on adults with nonvalvular atrial fibrillation as ...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2017/0901/p332.html

Niacin Does Not Decrease Mortality in Patients with Coronary Artery Disease or Low HDL ...

Jul 15, 2017 - We are now flush with data about the effects of niacin in patients with elevated cholesterol levels. Despite its ability to raise high-density lipoprotein (HDL) serum cholesterol levels, it does not add additional mortality or morbidity benefit to statin treatment. Patients with ...

American Family Physician : POEMs

https://www.aafp.org/afp/2017/0715/p129.html

Niacin Does Not Improve Clinical Outcomes in Patients with Vascular Disease - POEMs - ...

Nov 1, 2014 - This large, adequately powered trial did not find any clinically meaningful benefit to the use of niacin in patients who are already taking a statin, even with several study design features that should bias the result in favor of niacin. Niacin should not be prescribed to reduce the ...

American Family Physician : POEMs

https://www.aafp.org/afp/2014/1101/p660a.html

NICE Updates Guidelines on Management of Chronic Heart Failure - Practice Guidelines - ...

Apr 15, 2012 - Heart failure is associated with poor prognosis and quality of life, as well as high health care costs. In 2010, the National Institute for Health and Clinical Excellence (NICE) updated its previous guideline on the management of chronic heart failure in adults. This update focuses on ...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2012/0415/p832.html

Nicotine Receptor Partial Agonists for Smoking Cessation - Cochrane for Clinicians - ...

Oct 1, 2011 - Compared with placebo, varenicline more than doubles the chances of successful long-term smoking abstinence. In head-to-head trials, varenicline appears to be at least as effective as nicotine replacement therapy and bupropion (Zyban). The most common adverse effect is nausea, which ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2011/1001/p769.html

Nicotine Replacement Therapy for Smoking Cessation - Cochrane for Clinicians - American... Restricted content. Login required.

Jul 1, 2020 - Patients using a combination of nicotine patch and fast-acting NRT are more likely to quit smoking than those on any single therapy alone (number needed to treat [NNT] = 29; 95% CI, 20 to 47).

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2020/0701/p17.html

Nicotine Replacement Therapy for Smoking Cessation - Medicine by the Numbers - American...

Jul 1, 2015 - Studies show that 1 in 15 patients successfully quit smoking and 1 in 94 patients experienced chest pain or palpitations. Want to know more?

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2015/0701/od1.html

NIH Consensus Statement on Management of Hepatitis B - Practice Guidelines - American ...

Oct 15, 2009 - The National Institutes of Health (NIH) Consensus Development Panel has produced a report on the management of hepatitis B virus (HBV) created by independent panels of health professionals and public representatives using a systematic literature review.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2009/1015/p884.html

NIH Releases Statement on Managing Pain, Depression, and Fatigue in Cancer - Practice ...

Jan 15, 2003 - The National Institutes of Health (NIH) has released a statement on the management of cancer symptoms, including pain, depression, and fatigue. Physicians need to be able to identify who is at risk for these cancer-related symptoms, what treatments work best to address these problems, ...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2003/0115/p423.html

NIH Statement on Adjuvant Therapy for Breast Cancer - Practice Guidelines - American ...

May 1, 2001 - The National Institutes of Health (NIH) has released a statement on adjuvant therapy for breast cancer. Adjuvant therapies administered after surgery eradicate deposits of cancer cells that may have spread from the primary cancer site, and such therapies increase a woman's chance of ...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2001/0501/p1857.html

No Added Benefit with Higher Doses of Ketorolac for Treatment of Acute Pain in the ...

Aug 15, 2017 - A 10-mg dose of ketorolac is as effective as higher doses for the short-term treatment of acute pain for patients in the emergency department.

American Family Physician : POEMs

https://www.aafp.org/afp/2017/0815/p262.html

No Benefit to Addition of Stenting for Treatment of Atherosclerotic Renal Artery ...

Apr 1, 2014 - In patients with severe atherosclerotic renal artery stenosis and hypertension or chronic kidney disease, renal artery stenting does not provide an additional benefit when added to comprehensive medical therapy that includes blood pressure and diabetes mellitus management, and ...

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0401/p576.html

No Benefit to Prolonged Dual Antiplatelet Therapy After Drug-Eluting Stent Placement - ...

Oct 1, 2014 - Prolonging dual antiplatelet therapy with aspirin plus clopidogrel (Plavix) for more than one year after the placement of a drug-eluting stent confers no clinical benefit.

American Family Physician : POEMs

https://www.aafp.org/afp/2014/1001/p502.html

No Benefit with Addition of TMP/SMX to Cephalexin for Nonpurulent Cellulitis - POEMs - ...

Sep 15, 2017 - Compared with cephalexin alone, covering for methicillin-resistant Staphylococcus aureus (MRSA) and streptococci with cephalexin plus TMP/SMX does not improve rates of clinical cure when treating nonpurulent cellulitis. However, a trend favoring the combination regimen was found in a ...

American Family Physician : POEMs

https://www.aafp.org/afp/2017/0915/p399.html

No Benefit, Longer Hospital Stay with Treatment of Asymptomatic Bacteriuria - POEMs - ... Restricted content. Login required.

Feb 15, 2020 - Inappropriate treatment of asymptomatic bacteriuria is common in hospitalized patients. Older patients, those with dementia or acutely altered mental status, and those with abnormal urinalysis results are more likely to be treated with antibiotics.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0215/p248.html

No Effect on Mortality with Oxygen Therapy in Nonhypoxemic Patients with Suspected MI -...

Feb 15, 2018 - In patients with suspected MI and normal oxygen levels, giving immediate supplemental oxygen therapy does not improve mortality at one year. Although this study was underpowered because of fewer than expected deaths in the control group, the results were consistent across all subgroups,...

American Family Physician : POEMs

https://www.aafp.org/afp/2018/0215/od3.html

No Increased Risk of ASD, ADHD, or SGA with First-Trimester Antidepressant Use - POEMs ...

Aug 15, 2017 - This study found that maternal antidepressant use during the first trimester of pregnancy is associated with an increased risk of preterm birth, but not SGA, ASD, or ADHD. Another study in the same issue also reported no increased risk of ASD with in utero exposure to selective ...

American Family Physician : POEMs

https://www.aafp.org/afp/2017/0815/p261.html

No Increased Survival Benefit to Intensive Follow-Up After Colorectal Cancer Surgery - ...

May 1, 2014 - Compared with minimal follow-up after surgery for colorectal cancer, intensive follow-up with regular computed tomography (CT), carcinoembryonic antigen (CEA) testing, or both results in more patients undergoing repeat surgery but no reduction in overall mortality or disease-specific ...

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0501/p752.html

No Long-Term Benefit of Arthroscopic Surgery for Meniscal Tears in Middle-Aged Persons ...

May 1, 2015 - Arthroscopic repair of degenerative meniscal tears in middle-aged adults does not significantly improve long-term pain or function. Patients should do physical therapy and try to avoid surgery if possible.

American Family Physician : POEMs

https://www.aafp.org/afp/2015/0501/p643.html

No Reduction in Delirium with the Use of Haloperidol or Ziprasidone in Critically Ill ...

Apr 1, 2019 - For patients with acute respiratory failure or shock who develop delirium in the intensive care unit (ICU), the use of haloperidol or ziprasidone (Geodon) does not reduce the duration of delirium. This trial was powered to detect at least a two-day difference in the duration of ...

American Family Physician : POEMs

https://www.aafp.org/afp/2019/0401/p460.html

No Reduction in Readmissions with Telemonitoring, Coaching for Patients with Heart ...

Jul 15, 2016 - A care transition intervention that incorporates remote monitoring of weight, blood pressure, and heart rate with scheduled telephone coaching did not reduce readmission rates at 30 days or 180 days for patients with heart failure. However, patients in the study were only modestly ...

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0715/p168a.html

No Short-Term Extra Benefit when Muscle Relaxants Are Added to Ibuprofen for Acute Low ... Restricted content. Login required.

Jun 1, 2020 - Adding a muscle relaxant to treatment with ibuprofen does not improve functional outcomes or pain, or lessen the number of people reporting moderate to severe back pain one week after starting treatment.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0601/p695.html

Nocturnal Enuresis - Clinical Evidence Handbook - American Family Physician

May 1, 2006 - What are the effects of interventions for the relief of symptoms?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2006/0501/p1611.html

Noncontraceptive Uses of the Levonorgestrel Intrauterine System - Practice Guidelines -...

Nov 15, 2006 - Although the levonorgestrel-releasing intrauterine system (Mirena) is approved for contraception, it also may have noncontraceptive uses, such as treating idiopathic menorrhagia. The American College of Obstetricians and Gynecologists (ACOG) published a committee opinion to address the ...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2006/1115/p1792.html

Nonhormonal Therapies for Hot Flashes in Menopause - American Family Physician

Feb 1, 2006 - Numerous reports in the medical literature and popular media have discussed the effectiveness of various nonhormonal agents in reducing menopausal hot flash symptoms. Data for these therapies are limited, and most of the studies have been conducted in women with a history of breast ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0201/p457.html

Noninvasive Positive Pressure Ventilation for Exacerbation of Chronic Obstructive ... Restricted content. Login required.

Jun 1, 2020 - Chronic obstructive pulmonary disease (COPD) is a progressive lung disease characterized by hyperinflation of the lungs, including emphysema and chronic bronchitis. Learn more about the benefits and harms of using noninvasive positive pressure ventilation for exacerbation of COPD.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2020/0601/od1.html

Noninvasive Treatments for Low Back Pain - Implementing AHRQ Effective Health Care ...

Sep 1, 2017 - What are the benefits and harms of noninvasive treatments for acute, subacute, and chronic low back pain?

American Family Physician : Implementing AHRQ Effective Health Care Reviews

https://www.aafp.org/afp/2017/0901/p324.html

Nonmalignant Chronic Pain: Taking the Time to Treat - Curbside Consultation - American ...

May 1, 2009 - Nonmalignant chronic pain is a common, yet challenging, health problem.1 Numerous factors over the past decade have put primary care physicians in a central role in the management of this pain.

American Family Physician : Curbside Consultation

https://www.aafp.org/afp/2009/0501/p743.html

Nonoperative Management of Cervical Radiculopathy - American Family Physician

May 1, 2016 - Cervical radiculopathy describes pain in one or both of the upper extremities, often in the setting of neck pain, secondary to compression or irritation of nerve roots in the cervical spine. It can be accompanied by motor, sensory, or reflex deficits and is most prevalent in persons 50 ...

American Family Physician : Article

https://www.aafp.org/afp/2016/0501/p746.html

Nonopioid Pharmacologic Treatments for Chronic Pain - Implementing AHRQ Effective ... Restricted content. Login required.

May 1, 2021 - What are the effects of nonopioid drugs on pain, function, and quality of life in patients with specific types of chronic pain, and what are the adverse events related to these drugs?

American Family Physician : Implementing AHRQ Effective Health Care Reviews

https://www.aafp.org/afp/2021/0501/p561.html

Nonopioids Equivalent to Opioids for Severe Chronic Back, Hip, or Knee Pain with Fewer ...

Sep 1, 2018 - Nonopioid medications were at least as effective as opioid medications for improving pain-related function over 12 months in adults with severe chronic back pain or knee or hip osteoarthritis pain. The evidence that opioids are not superior to nonopioid medications for chronic and acute...

American Family Physician : POEMs

https://www.aafp.org/afp/2018/0901/p316.html

Nonpharmaceutical Treatment of Anxiety in Institutionalized Older Adults - FPIN's Help ...

Apr 1, 2016 - Cognitive behavior therapy (CBT) or relaxation training, alone or in combination, can be used to treat anxiety in older adults. Music therapy can also be used to reduce anxiety in older adults. Appropriate training of institutional caregivers is also helpful in reducing anxiety in older...

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2016/0401/p592.html

Nonpharmacologic Approaches Are Better Than Medication to Control Aggression and ... Restricted content. Login required.

May 15, 2020 - Nonpharmacologic approaches to agitation or aggression in patients with dementia are more effective than medication (e.g., haloperidol). Outdoor activities, multidisciplinary care, and massage and touch therapy with or without music are all effective.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0515/p631a.html

Nonpharmacologic Management of Chronic Insomnia - American Family Physician

Dec 15, 2015 - Insomnia affects 10% to 30% of the population with a total cost of $92.5 to $107.5 billion annually. Short-term, chronic, and other types of insomnia are the three major categories according to the International Classification of Sleep Disorders, 3rd ed. The criteria for diagnosis are ...

American Family Physician : Article

https://www.aafp.org/afp/2015/1215/p1058.html

Nonpharmacologic Management of Chronic Insomnia - American Family Physician

Jan 15, 2009 - Chronic insomnia is highly prevalent in our society, with an incidence of 10 to 30 percent. It is a major cost to society in terms of health care expenditure and reduced productivity. Nonpharmacologic interventions have been studied and shown to produce reliable and sustained ...

American Family Physician : Article

https://www.aafp.org/afp/2009/0115/p125.html

Nonpharmacologic Management of Hypertension: What Works? - American Family Physician

Jun 1, 2015 - Hypertension is one of the most common conditions encountered in primary care. Nonpharmacologic strategies have been shown to help lower blood pressure. Lifestyle modifications are recommended for all patients with hypertension. The American Heart Association/American College of ...

American Family Physician : Article

https://www.aafp.org/afp/2015/0601/p772.html

Nonpharmacologic Strategies for Managing Hypertension - American Family Physician

Jun 1, 2006 - The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure recommends lifestyle modification for all patients with hypertension or prehypertension. Modifications include reducing dietary sodium to less than 2.4 g per ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0601/p1953.html

Nonpharmacologic vs. Anticholinergic Therapies for Overactive Bladder - Cochrane for ...

May 1, 2007 - Anticholinergic medications are more effective than bladder training in reducing the number of voids per day. Combining an anti-cholinergic medication with bladder training is more effective than either therapy alone.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0501/p1336.html

Nonsteroidal Anti-Inflammatory Drug Injections for Trigger Finger - Medicine by the ... Restricted content. Login required.

Sep 1, 2021 - Learn more about nonsteroidal anti-inflammatory drug injections for trigger finger.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2021/1100/od2.html

Nonsteroidal Anti-inflammatory Drugs - Clinical Evidence Handbook - American Family ...

Feb 1, 2006 - Are there any important differences between available nonsteroidal anti-inflammatory drugs (NSAIDs)? What are the effects of cotreatments on reducing the risk of the adverse gastrointestinal effects of NSAIDs? What are the effects of topical NSAIDs?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2006/0201/p507.html

Nonsurgical Management of Knee Pain in Adults - American Family Physician

Nov 15, 2015 - The role of the family physician in managing knee pain is expanding as recent literature supports nonsurgical management for many patients. Effective treatment depends on the etiology of knee pain. Oral analgesics—most commonly nonsteroidal anti-inflammatory drugs and acetaminophen—are ...

American Family Physician : Article

https://www.aafp.org/afp/2015/1115/p875.html

Nontraumatic Supraspinatus Tears: PT Is Equal to PT Plus Surgery at One Year - POEMs - ...

May 15, 2014 - In this study, the long-term outcomes of adults with nontraumatic supraspinatus tears who are treated conservatively are similar to those of patients treated with two different surgical approaches.

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0515/p824.html

NPH Insulin: Fewer Episodes of Severe Hypoglycemia Than Analogs and Less Than One-Half ...

Jan 1, 2019 - This study found that compared with expensive long-acting insulin analogs costing two to 10 times as much, NPH insulin results in a similar number of episodes of severe hypoglycemia (if not fewer) that result in emergency department visits and hospitalizations.

American Family Physician : POEMs

https://www.aafp.org/afp/2019/0101/p53a.html

NSAID Prescribing Precautions - American Family Physician

Dec 15, 2009 - Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used, but have risks associated with their use, including significant upper gastrointestinal tract bleeding. Older persons, persons taking anticoagulants, and persons with a history of upper gastrointestinal tract bleeding ...

American Family Physician : Article

https://www.aafp.org/afp/2009/1215/p1371.html

NSAIDs Alone or with Opioids as Therapy for Cancer Pain - Cochrane for Clinicians - ...

Aug 1, 2005 - Short-term trials indicate that cancer pain can be reduced with the use of nonsteroidal anti-inflammatory drugs (NSAIDs) as initial monotherapy. NSAIDs combined with opioids can result in slight short-term improvement in pain compared with either agent alone. Long-term efficacy and ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/0801/p436.html

NSAIDs for Postpartum Perineal Pain - FPIN's Help Desk Answers - American Family Physician

Jun 1, 2018 - Women with third- or fourth-degree perineal lacerations or who received an episiotomy can be given oral NSAIDs to reduce perineal pain in the first six hours postpartum.

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2018/0601/od3.html

NSAIDs vs. Acetaminophen for the Treatment of Ankle Sprains - AFP Journal Club - ...

Dec 1, 2007 - Are NSAIDs better than acetaminophen for ankle sprains? Extended-release acetaminophen provides equivalent analgesia and return to activity as an NSAID in patients with mild to moderate ankle sprains. All NSAIDs have equivalent analgesic effect.

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2007/1201/p1605.html

NSAIDs vs. Opiates for Pain in Acute Renal Colic - Cochrane for Clinicians - American ...

Nov 1, 2004 - Data from randomized controlled trials comparing NSAIDs with opiates show that NSAIDs are associated with lower pain scores, less need for additional rescue medication, and less vomiting (particularly when compared with meperidine).

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2004/1101/p1682.html

Nutritional Assessment and Counseling for Prevention and Treatment of Cardiovascular ...

Jan 15, 2006 - Physicians face several barriers to counseling their patients about nutrition, including conflicting evidence of the benefit of counseling, limited training and understanding of the topic, and imperfect and varied guidelines to follow. Because cardiovascular disease remains the leading ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0115/p257.html

Obesity - Clinical Evidence Handbook - American Family Physician

Oct 1, 2002 - What are the effects of drug treatments for obesity in adults?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2002/1001/p1279.html

Obesity in Adults - Clinical Evidence Handbook - American Family Physician

Oct 15, 2010 - What are the effects of drug treatments in adults with obesity? What are the effects of bariatric surgery in adults with morbid obesity?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2010/1015/p974.html

Obesity in Children - Clinical Evidence Handbook - American Family Physician

Dec 1, 2007 - What are the effects of lifestyle interventions for the treatment of childhood obesity?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2007/1201/p1701.html

Obsessive-Compulsive Disorder - Clinical Evidence Handbook - American Family Physician

Dec 1, 2004 - What are the effects of initial treatments in adults? What are the best forms of maintenance treatment in adults? What are the effects of treatments in adults who have not responded to initial treatment with serotonin reuptake inhibitors?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2004/1201/p2183.html

Obstetric Lacerations: Prevention and Repair - American Family Physician Restricted content. Login required.

Jun 15, 2021 - Obstetric lacerations are a common complication of vaginal delivery. Lacerations can lead to chronic pain and urinary and fecal incontinence. Perineal lacerations are defined by the depth of musculature involved, with fourth-degree lacerations disrupting the anal sphincter and the ...

American Family Physician : Article

https://www.aafp.org/afp/2021/0615/p745.html

Obstructive Sleep Apnea and Chronic Insomnia Disorder: Updated Guidelines from the ... Restricted content. Login required.

Apr 1, 2021 - The U.S. Department of Veterans Affairs and Department of Defense (VA/DoD) approved a clinical practice guideline for the management of obstructive sleep apnea and chronic insomnia disorder.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2021/0401/p442.html

Occupational Therapy Improves Activities of Daily Living After Stroke - Cochrane for ...

Jun 1, 2007 - Compared with standard rehabilitation, ADL-based occupational therapy significantly decreases death or institutionalization and deterioration in the ability to perform ADL after stroke. The optimal length and type of therapy is not well defined.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0601/p1651.html

Off-Label Applications for SSRIs - American Family Physician

Aug 1, 2003 - Selective serotonin reuptake inhibitors (SSRIs) are widely used because of their safety, tolerability, and demonstrated efficacy across a broad range of clinical conditions. Medical literature supports the use of SSRIs for the treatment of many conditions outside of the indications ...

American Family Physician : Article

https://www.aafp.org/afp/2003/0801/p498.html

Off-Label Use and Misuse of Hormone Supplements: AACE and ACE Position Statement - ... Restricted content. Login required.

Dec 15, 2020 - The American Association of Clinical Endocrinologists and the American College of Endocrinology developed a summary of known risks of using off-label hormone treatments.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2020/1215/p759.html

Off-label Use of Prescription Drugs - Editorials - American Family Physician

Aug 1, 2003 - Advertisement << Previous article Next article >> Aug 1, 2003 Issue Editorials Off-Label Use of Prescription Drugs STUART L. NIGHTINGALE, M.D., Office of the Secretary, U.S. Department of Health and Human Services, Washington, D.C. Am Fam Physician. 2003 Aug 1;68(3):425-427. Related...

American Family Physician : Editorials

https://www.aafp.org/afp/2003/0801/p425.html

Office Management of Bartholin Gland Cysts and Abscesses - American Family Physician

Apr 1, 1998 - Bartholin gland cysts and abscesses are common problems in women of reproductive age. Although the cysts are usually asymptomatic, they may become enlarged or infected and cause significant pain. Often the clinician is tempted simply to lance the cyst or abscess, since this technique ...

American Family Physician : Article

https://www.aafp.org/afp/1998/0401/p1611.html

Office Management of Digital Mucous Cysts - American Family Physician

Dec 15, 2001 - Digital mucous cysts are solitary, clear, or flesh-colored nodules that develop on the dorsal digits between the distal interphalangeal joint and the proximal nail fold. There are two types of digital mucous cysts: one type is associated with degenerative changes in the distal ...

American Family Physician : Article

https://www.aafp.org/afp/2001/1215/p1987.html

Office Management of Early Pregnancy Loss - American Family Physician

Jul 1, 2011 - The management of early pregnancy loss used to be based largely in the hospital setting, but it has shifted to the outpatient setting, allowing women to remain under the care of their family physician throughout the miscarriage process. Up to 15 percent of recognized pregnancies end in ...

American Family Physician : Article

https://www.aafp.org/afp/2011/0701/p75.html

Office-Based Strategies for the Management of Obesity - American Family Physician

Jun 15, 2010 - Roughly two thirds of U.S. adults are overweight or obese. Obesity increases the risk of hypertension, type 2 diabetes mellitus, hyperlipidemia, heart disease, pulmonary disease, hepatobiliary disease, cancer, and a number of psychosocial complications. Physicians often feel unprepared ...

American Family Physician : Article

https://www.aafp.org/afp/2010/0615/p1449.html

Omalizumab (Xolair) for Treatment of Asthma - STEPS - American Family Physician

Jan 15, 2005 - Omalizumab is an immunomodulatory therapy for the control of symptoms in patients with moderate to severe allergic asthma uncontrolled with conventional therapy. Given its high cost, the requirement that it be administered in a physician’s office, and side effects, it is appropriate for...

American Family Physician : STEPS

https://www.aafp.org/afp/2005/0115/p341.html

Omega-3 Fatty Acids - American Family Physician

Jul 1, 2004 - Omega-3 fatty acids have been shown to significantly reduce the risk for sudden death caused by cardiac arrhythmias and all-cause mortality in patients with known coronary heart disease. Fatty fish, such as salmon and tuna, and fish oil are rich sources of the omega-3 fatty acids ...

American Family Physician : Article

https://www.aafp.org/afp/2004/0701/p133.html

OnabotulinumtoxinA for Prevention of Migraine in Adults - Cochrane for Clinicians - ... Restricted content. Login required.

Feb 1, 2020 - OnabotulinumtoxinA reduces the number of migraine days per month by two days compared with placebo in adults with chronic migraines.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2020/0201/p144.html

OnabotulinumtoxinA Injections for Urge Incontinence - FPIN's Help Desk Answers - ...

Feb 1, 2018 - Detrusor muscle injections of onabotulinumtoxinA can be used to decrease the number of episodes of urinary incontinence in women for whom treatment with anticholinergic agents has been ineffective.

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2018/0201/od3.html

Once-Weekly Semaglutide Is an Effective Adjunct for Weight Loss in Adults without ... Restricted content. Login required.

Jul 1, 2021 - Once-weekly subcutaneous semaglutide used as an adjunct to intensive behavioral therapy significantly improves the likelihood that adults without diabetes who are overweight or obese will lose at least 5% of their baseline body weight compared with placebo.

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0700/p96.html

Oncologic Emergencies: Recognition and Initial Management - American Family Physician

Jun 1, 2018 - Most oncologic emergencies can be classified as metabolic, hematologic, structural, or treatment related. Tumor lysis syndrome is a metabolic emergency that presents as severe electrolyte abnormalities. Stabilization is focused on vigorous rehydration, maintaining urine output, and ...

American Family Physician : Article

https://www.aafp.org/afp/2018/0601/p741.html

Ondansetron for Gastroenteritis in Children and Adolescents - Medicine by the Numbers -...

Apr 1, 2015 - Studies show vomiting stopped in 1 in 5 patients and diarrhea was a consistent adverse effect. Find out more.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2015/0401/od3.html

One Month of Dual Antiplatelet Therapy Followed by Clopidogrel Alone is Superior to 12 ... Restricted content. Login required.

Dec 15, 2019 - This study found that one month of dual antiplatelet therapy (aspirin plus clopidogrel or prasugrel [Effient]) followed by clopidogrel monotherapy for up to five years is both noninferior and superior to 12 months of dual antiplatelet therapy followed by aspirin for up to five years for...

American Family Physician : POEMs

https://www.aafp.org/afp/2019/1215/od5.html

One-Third of Adults with Diagnosed Asthma Can Be Weaned Off All Asthma Medications - ...

May 1, 2017 - This study found that current asthma was ruled out after repeated testing in one-third of adults with physician-diagnosed asthma. Patients ruled out for current asthma were less likely to be using asthma medications or daily controlling medications and less likely to have undergone ...

American Family Physician : POEMs

https://www.aafp.org/afp/2017/0501/p586.html

One-Third of Patients with Anxiety Disorder Will Relapse When Antidepressant Treatment ...

May 1, 2018 - Discontinuing the antidepressant treatment in patients with anxiety disorders will cause a relapse in almost one-third of them. One in six patients previously treated successfully will also relapse despite continued treatment.

American Family Physician : POEMs

https://www.aafp.org/afp/2018/0501/p605.html

Opioid Abuse and Pain Management - Editorials - American Family Physician

Oct 1, 2012 - Chronic nonmalignant pain affects a significant number of Americans. Concurrent with the increased need for pain management is a considerable increase in the use of prescription pain relievers for nonmedical purposes. Nonmedical use of prescription pain relievers is now the second most ...

American Family Physician : Editorials

https://www.aafp.org/afp/2012/1001/p600.html

Opioid Antagonists for the Treatment of Alcohol Dependence - Cochrane for Clinicians - ...

Nov 1, 2011 - Although it does not improve overall alcohol abstinence rates, the oral formulation of the opioid antagonist naltrexone (Revia) is moderately effective in decreasing the amount and frequency of alcohol consumption in patients with alcohol dependence.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2011/1101/p990.html

Opioid Dependence - Clinical Evidence Handbook - American Family Physician

Sep 15, 2012 - What are the effects of drug treatments for stabilization (maintenance), withdrawal, and relapse prevention in persons with opioid dependence?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2012/0915/p565.html

Opioid Therapy for Chronic Noncancer Pain - Cochrane for Clinicians - American Family ...

Jul 1, 2010 - Weak evidence suggests that opioids reduce chronic noncancer pain in some highly selected patients, although the effects on quality of life and functional status are unclear.1 Many patients will discontinue opioids because of adverse effects or inadequate pain relief.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2010/0701/p40.html

Opioid Use Disorder: Medical Treatment Options - American Family Physician

Oct 1, 2019 - Opioid use disorder is highly prevalent and can be fatal. At least 2.1 million Americans 12 years and older had opioid use disorder in 2016, and approximately 47,000 Americans died from opioid overdoses in 2017. Opioid use disorder is a chronic relapsing condition, the treatment of ...

American Family Physician : Article

https://www.aafp.org/afp/2019/1001/p416.html

Opioids for Chronic Back Pain: Short-Term Effectiveness, Long-Term Uncertain - POEMs - ...

Aug 15, 2014 - Overall, in patients with chronic low-back pain, opioids are moderately more effective than placebo in the short term for pain relief and slightly more effective in the short term for improving function. However, data for long-term use are virtually nonexistent. The long-term use of ...

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0815/od5.html

Opioids for Management of Breakthrough Pain in Cancer Patients - Cochrane for ...

Dec 1, 2006 - Oral transmucosal fentanyl citrate (OTFC [Actiq]), a rapid-acting opioid, has been shown to be an effective treatment for breakthrough cancer pain. Other opioids, including immediate-release oral morphine (MSIR), also may be effective; however, evidence comparing these agents with OTFC ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/1201/p1855.html

Opioids for Osteoarthritis of the Knee or Hip - Cochrane for Clinicians - American ...

May 1, 2010 - Compared with placebo, the benefits achieved from opioid therapy are modest in terms of pain relief and improvement in function, and do not outweigh the increase in adverse effects. No single opioid stands out as more effective or safer than the rest.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2010/0501/p1094.html

Opportunities to Improve Outcomes in Sickle Cell Disease - American Family Physician

Jul 15, 2006 - Sickle cell disease represents a spectrum of inherited hemoglobin disorders. The pathophysiology involves abnormalities not just in red blood cells but also vascular endothelium, white blood cell function, coagulation, and inflammatory response. Known sequelae of sickle cell disease ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0715/p303.html

Oppositional Defiant Disorder - American Family Physician

Oct 1, 2008 - Oppositional defiant disorder is defined by the Diagnostic and Statistical Manual of Mental Disorders, 4th ed., as a recurrent pattern of developmentally inappropriate, negativistic, defiant, and disobedient behavior toward authority figures. This behavior often appears in the preschool...

American Family Physician : Article

https://www.aafp.org/afp/2008/1001/p861.html

Optimal Antibiotic Regimen for Treating Lower UTI in Children - Cochrane for Clinicians...

Nov 1, 2013 - For the afebrile child with a UTI, a short course (three to seven days) of antibiotics is as effective at preventing the recurrence of symptomatic UTI as a long course (seven to 10 days). There is no clear evidence of superiority for any one antibiotic regimen.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/1101/p577.html

Optimal Dosage of Tricyclic Antidepressants - Cochrane for Clinicians - American Family...

Oct 1, 2004 - Although the quality of the data limits the strength of the recommendation, current evidence shows that 75 to 100 mg per day of a tricyclic antidepressant is more effective than placebo. Higher dosages are not more effective and are associated with more dropouts because of side effects.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2004/1001/p1270.html

Optimal Duration of Treatment Regimens for H. pylori Eradication - Cochrane for ...

Dec 1, 2014 - When using proton pump inhibitor (PPI) triple therapy, increasing the duration of treatment from seven to 10 days or from 10 to 14 days significantly increases the eradication of H. pylori. When using other treatment regimens, it is unclear whether increasing duration of treatment ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/1201/p766.html

Optimal Management of Cholesterol Levels and the Prevention of Coronary Heart Disease ...

Jan 15, 2002 - Coronary heart disease, the leading cause of death in women, is largely preventable. Lifestyle modifications (e.g., diet and exercise) are the cornerstone of primary and secondary prevention. Elevated levels of low-density lipoprotein cholesterol and triglycerides and low levels of ...

American Family Physician : Article

https://www.aafp.org/afp/2002/0115/p217.html

Optimal Treatment of Acute Venous Thromboembolism - POEMs - American Family Physician

Apr 1, 2015 - This complex network meta-analysis of eight treatment regimens for acute venous thromboembolism found that a combination of unfractionated heparin and vitamin K antagonists is associated with the least effective strategy with the highest risk of recurrent events.

American Family Physician : POEMs

https://www.aafp.org/afp/2015/0401/p492.html

Optimizing Beta-Blocker Use After Myocardial Infarction - American Family Physician

Oct 15, 2000 - Although beta-adrenergic blockers can significantly reduce mortality after a myocardial infarction, these agents are prescribed to only a minority of patients. Underutilization of beta blockers may be attributed, in part, to fear of adverse effects, especially in the elderly and in ...

American Family Physician : Article

https://www.aafp.org/afp/2000/1015/p1853.html

Options for Women with Unintended Pregnancy - American Family Physician

Apr 15, 2015 - Unintended pregnancy refers to unwanted, unplanned, or mistimed pregnancies. One-half of all pregnancies in the United States are unintended, and family physicians are often asked to provide counseling, support, and resources for women with unintended pregnancies. Options include ...

American Family Physician : Article

https://www.aafp.org/afp/2015/0415/p544.html

Oral Agents in the Management of Type 2 Diabetes Mellitus - American Family Physician

May 1, 2001 - Despite exhaustive efforts to better manage patients with type 2 diabetes mellitus (formerly known as non-insulin-dependent diabetes mellitus), attempts at maintaining near normal blood glucose levels in these patients remains unsatisfactory. This continues to pose a real challenge to ...

American Family Physician : Article

https://www.aafp.org/afp/2001/0501/p1747.html

Oral Analgesics for Acute Nonspecific Pain - American Family Physician

Mar 1, 2005 - Physicians most often recommend or prescribe oral medication for relief of acute pain. This review of the available evidence supports the use of acetaminophen in doses up to 1,000 mg as the initial choice for mild to moderate acute pain. In some cases, modest improvements in analgesic ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0301/p913.html

Oral Antibiotics Are Equal to IV Antibiotics for Serous Bone and Joint Infections - ...

Oct 1, 2019 - Oral antibiotics started within seven days of surgery for patients with a serious bone or joint infection are as safe and effective as six weeks of IV antibiotics.

American Family Physician : POEMs

https://www.aafp.org/afp/2019/1001/p441.html

Oral Anticoagulants vs. Antiplatelet Therapy - Cochrane for Clinicians - American ...

May 1, 2008 - Compared with antiplatelet therapy, oral anticoagulation significantly reduces stroke at an average follow-up of one to three years, but does not reduce mortality. Intracranial or extracranial hemorrhage is more common with anticoagulation and must be weighed against its therapeutic ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2008/0501/p1250.html

Oral Antihistamine/Decongestant/Analgesic Combinations for the Common Cold - Cochrane ...

Nov 1, 2012 - Combination cold medications, including antihistamine/decongestant/analgesic, antihistamine/decongestant, antihistamine/analgesic, and analgesic/decongestant formulations, provide modest symptom relief in adults and older children, but are not effective in young children. Only the ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2012/1101/p812.html

Oral Appliances for Obstructive Sleep Apnea? - Cochrane for Clinicians - American ...

Mar 1, 2006 - Although oral appliances provide improved subjective sleepiness and sleep-disordered breathing, continuous positive airway pressure (CPAP) is more effective. Oral appliances should not be used as a first-line treatment but rather should be reserved for patients who cannot tolerate CPAP ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/0301/p801.html

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