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An Oral Appliance Does Not Improve Sleep in Patients with Less Severe Sleep Apnea - ...

Dec 1, 2015 - An oral appliance does not improve daytime sleepiness or other measures of a good night's sleep. It does, however, decrease apnea scores, snoring, and restless legs. Although not studied, these improvements may be valuable for bed partners who sleep each night enduring patients' lower ...

American Family Physician : POEMs

https://www.aafp.org/afp/2015/1201/p1021.html

An Update on Emergency Contraception - American Family Physician

Apr 1, 2014 - Emergency contraception decreases the risk of unintended pregnancy after unprotected sexual intercourse or after suspected failure of routine contraception (e.g., a condom breaking). Oral methods include combined contraceptive pills (i.e., Yuzpe method), single- or split-dose ...

American Family Physician : Article

https://www.aafp.org/afp/2014/0401/p545.html

Analgesics for Osteoarthritis - Implementing AHRQ Effective Health Care Reviews - ...

Mar 1, 2013 - What are the comparative effectiveness, benefits, and adverse effects of oral and topical analgesics for osteoarthritis?

American Family Physician : Implementing AHRQ Effective Health Care Reviews

https://www.aafp.org/afp/2013/0301/p354.html

Anaphylaxis: Recognition and Management - American Family Physician

Nov 15, 2011 - Anaphylaxis is a severe, life-threatening, systemic allergic reaction that is almost always unanticipated and may lead to death by airway obstruction or vascular collapse. Anaphylaxis occurs as the result of an allergen response, usually immunoglobulin E–mediated, which leads to mast ...

American Family Physician : Article

https://www.aafp.org/afp/2011/1115/p1111.html

Anastrozole Decreases Rate of Breast Cancer in High-Risk Postmenopausal Women - POEMs -...

Aug 15, 2014 - Postmenopausal women at high risk of developing breast cancer who take anastrozole for five years have a lower rate of developing invasive breast cancer during that time frame.

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0815/od7.html

Angiotensin Blockade in Patients with Diabetic Nephropathy - FPIN's Clinical Inquiries ...

Aug 1, 2007 - When used to delay the progression of early nephropathy in patients with type 2 diabetes mellitus, angiotensin receptor blockers (ARBs) are not superior to angiotensin-converting enzyme (ACE) inhibitors.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2007/0801/p423.html

Angiotensin II Receptor Antagonists in the Treatment of Hypertension - American Family ...

Sep 15, 1999 - The sixth report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC-VI) includes recommendations for the assessment of overall cardiovascular risk and the need for active antihypertensive drug therapy. Once the decision to ...

American Family Physician : Article

https://www.aafp.org/afp/1999/0915/p1185.html

Angiotensin-Converting Enzyme Inhibitors vs. Angiotensin Receptor Blockers - FPIN's ...

Feb 1, 2015 - ACE inhibitors should be used in patients with hypertension because they reduce all-cause mortality, whereas ARBs do not.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2015/0201/p193.html

Angiotensin-II Receptor Antagonists: Their Place in Therapy - American Family Physician

Jun 1, 1999 - Angiotensin-II receptor antagonists (or blockers) are a newer class of antihypertensive agents. These drugs are selective for angiotensin II (type 1 receptor); unlike angiotensin-converting enzyme inhibitors, they do not inhibit bradykinin metabolism or enhance prostaglandin synthesis. ...

American Family Physician : Article

https://www.aafp.org/afp/1999/0601/p3140.html

Antibiotic Prophylaxis for COPD Exacerbations - FPIN's Clinical Inquiries - American ...

Apr 15, 2018 - Prophylactic antibiotics may be used to reduce the overall rate of COPD exacerbations and delay their onset. However, the appropriate antibiotic regimen and target population are unclear.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2018/0415/p527.html

Antibiotic Prophylaxis for Operative Vaginal Delivery - Medicine by the Numbers - ... Restricted content. Login required.

Oct 1, 2020 - Current guidelines from the World Health Organization do not recommend routine antibiotic prophylaxis for operative vaginal birth because of insufficient evidence of effectiveness.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2020/1001/od2.html

Antibiotic Prophylaxis for Severe Acute Pancreatitis - FPIN's Help Desk Answers - ...

Jan 1, 2019 - No, antibiotic prophylaxis does not decrease mortality in patients with severe acute pancreatitis, defined as pancreatitis associated with pancreatic necrosis.

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2019/0101/p49.html

Antibiotic Prophylaxis in Patients with Cirrhosis and Upper Gastrointestinal Bleeding -...

May 1, 2017 - Antibiotics should be used for prophylaxis in hospitalized patients with cirrhosis and upper gastrointestinal bleeding. Prophylaxis reduces all-cause mortality by 21%, as well as bacterial infections and rebleeding.

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2017/0501/p582.html

Antibiotic Prophylaxis in Patients with COPD - Medicine by the Numbers - American ...

Jun 1, 2019 - This research fails to determine whether the modest potential benefits of antibiotic prophylaxis in patients with chronic obstructive pulmonary disease outweigh the risk of resistance. Find out more.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2019/0601/od1.html

Antibiotic Resistance Threats in the United States: Stepping Back from the Brink - ...

Jun 15, 2014 - Preventing and controlling resistance requires the engagement of many different sectors of society. However, the physician's role in this effort is singularly important.

American Family Physician : Editorials

https://www.aafp.org/afp/2014/0615/p938.html

Antibiotic Use in Acute Upper Respiratory Tract Infections - American Family Physician

Nov 1, 2012 - Upper respiratory tract infections account for millions of visits to family physicians each year in the United States. Although warranted in some cases, antibiotics are greatly overused. This article outlines the guidelines and indications for appropriate antibiotic use for common upper...

American Family Physician : Article

https://www.aafp.org/afp/2012/1101/p817.html

Antibiotics for Acute Laryngitis in Adults - Cochrane for Clinicians - American Family ...

Jul 1, 2005 - Two small trials of antibiotic treatment in acute laryngitis do not support routine use of antibiotics in these patients. Most patients will feel better in five to seven days, and it is unlikely that they will experience a clinically important benefit from antibiotics.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/0701/p76.html

Antibiotics for Acute Maxillary Sinusitis - Cochrane for Clinicians - American Family ...

May 1, 2009 - Although there is some evidence that antibiotics are effective in the treatment of acute uncomplicated sinusitis, this benefit is modest. Most patients with acute sinusitis improve within two weeks without antibiotics. The potential risk of adverse effects from antibiotics may outweigh ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2009/0501/p757.html

Antibiotics for Acute Otitis Media in Young Children - AFP Journal Club - American ...

Nov 15, 2011 - Two studies aim to clarify the appropriate use of antibiotic treatment in young children with acute otitis media.

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2011/1115/p1095.html

Antibiotics for Acute Otitis Media in Young Children: The Case of the Shifting End ...

Jan 15, 2012 - A discussion of why the conclusion of a high-profile study, which suggests that antibiotics are beneficial in children six to 23 months of age with acute otitis media, is incorrect.

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2012/0115/p104.html

Antibiotics for Acute Rhinosinusitis in Adults - Medicine by the Numbers - American ...

Oct 1, 2019 - Because of the relatively high rate of reported adverse effects and the high likelihood of resolution of symptoms with supportive care and symptomatic management, the authors recommend selective antibiotic use in patients with acute sinusitis. Read more.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2019/1001/od1.html

Antibiotics for Exacerbations of Chronic Obstructive Pulmonary Disease - Medicine by ... Restricted content. Login required.

Feb 1, 2020 - Prescription of antibiotics for the treatment of chronic obstructive pulmonary disease (COPD) is controversial due to the variety of etiologies. This review examined the use of antibiotics to treat COPD in outpatient, inpatient, and ICU settings. Read more.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2020/0201/od1.html

Antibiotics for Exacerbations of COPD - Cochrane for Clinicians - American Family ...

Sep 1, 2006 - There is consistent evidence from a small number of studies that antibiotics significantly reduce mortality (number needed to treat [NNT] = 8) and treatment failure (NNT = 3) in more severely ill patients with COPD who are hospitalized because of an exacerbation. Two smaller studies ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/0901/p749.html

Antibiotics for Otitis Media in Children - Medicine by the Numbers - American Family ...

Jun 15, 2018 - This meta-analysis concludes that the risk of a prolonged course of antibiotics was twice as high for children younger than two years with bilateral acute otitis media than for children two years and older with unilateral acute otitis media, indicating that antibiotics might be ...

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2018/0615/od3.html

Antibiotics for Recurrent Urinary Tract Infections - Cochrane for Clinicians - American...

Apr 1, 2005 - Prophylactic antibiotics can reduce the number of recurrent UTIs in nonpregnant women while they are taking the medication (relative risk [RR], 0.21; number needed to treat [NNT], 2). No antibiotic was significantly better than others at decreasing the number of UTIs, and all ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/0401/p1301.html

Antibiotics for Sore Throat - Cochrane for Clinicians - American Family Physician

Jul 1, 2014 - Compared with placebo, antibiotics can shorten the duration of sore throat symptoms by about 16 hours and can reduce complications. In countries where the absolute rates of complications are higher, antibiotic therapy is more likely to be effective. The effectiveness of antibiotic ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/0701/p23.html

Antibiotics for Uncomplicated Skin Abscesses After Incision and Drainage: BMJ Rapid ...

Sep 1, 2018 - A collaboration between the BMJ and the MAGIC group led an international panel made up of a variety of health care professionals (e.g., family physicians, internists, dermatologists) and adults with experience treating and living with skin abscesses to create recommendations regarding ...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2018/0901/p323.html

Antibiotics for Viral Upper Respiratory Tract Infections in Children - FPIN's Clinical ...

Mar 15, 2011 - Antibiotic therapy does not benefit children with bronchiolitis, the common cold, or nonstreptococcal pharyngitis. If purulent rhinitis is present for more than 10 days, antibiotics shorten the duration of runny nose symptoms.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2011/0315/p747.html

Antibiotics May Equal Surgery for Children with Appendicitis - POEMs - American Family ...

Jun 1, 2017 - Antibiotic treatment appears to be effective for children with uncomplicated appendicitis without evidence of perforation or rupture, with 97% of children discharged without surgery. Approximately one in seven children will eventually have recurrence and require surgery. A couple of ...

American Family Physician : POEMs

https://www.aafp.org/afp/2017/0601/p737.html

Anticholinergic Drugs for Overactive Bladder - Cochrane for Clinicians - American ...

Jan 1, 2006 - Tolterodine (Detrol) is as effective as immediate-release oxybutynin (Ditropan) and causes less dry mouth. A dose of 1 mg tolterodine twice daily is as effective as higher dosages of tolterodine. Extended-release preparations have less risk of dry mouth but are more expensive.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/0101/p66.html

Anticoagulation for the Long-term Treatment of VTE in Patients with Cancer - Cochrane ...

Jun 1, 2019 - Low-molecular-weight heparin (LMWH), vitamin K antagonists, and direct oral anticoagulants, when used to prevent recurrent VTE, have a similar impact on all-cause mortality.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0601/p676.html

Anticoagulation for the Long-term Treatment of VTE in Patients with Cancer - Cochrane ...

Jul 1, 2009 - Although LMWH appears to be more effective than oral anticoagulants in the prevention of recurrent VTE, this does not translate into a survival benefit. LMWH and oral anticoagulants have the same reported adverse events of bleeding and thrombocytopenia.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2009/0701/p30.html

Anticoagulation in Elderly Persons: A Call for Wider Use - Editorials - American Family...

Jul 1, 1998 - Advertisement << Previous article Next article >> Jul 01, 1998 Issue Editorials Anticoagulation in Elderly Persons: A Call for Wider Use VALERY A. PORTNOI, M.D., Albert Einstein College of Medicine of Yeshiva, University Beth Israel Medical Center, New York, New York Am Fam...

American Family Physician : Editorials

https://www.aafp.org/afp/1998/0701/p39.html

Anticoagulation: Updated Guidelines for Outpatient Management - American Family Physician

Oct 1, 2019 - Anticoagulation therapy is recommended for preventing, treating, and reducing the recurrence of venous thromboembolism, and preventing stroke in persons with atrial fibrillation. Direct oral anticoagulants are first-line agents for eligible patients for treating venous thromboembolism ...

American Family Physician : Article

https://www.aafp.org/afp/2019/1001/p426.html

Anticonvulsant Medications for Migraine Prevention - Cochrane for Clinicians - American...

May 1, 2005 - Good evidence supports the use of anticonvulsants as a class with overall reduction in number of headaches per month and overall increase in patients achieving 50 percent reduction of headache frequency. Of the medications within this heterogeneous group, valproic acid and divalproex ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/0501/p1699.html

Antidepressant Discontinuation Syndrome - American Family Physician

Aug 1, 2006 - Antidepressant discontinuation syndrome occurs in approximately 20 percent of patients after abrupt discontinuation of an antidepressant medication that was taken for at least six weeks. Typical symptoms of antidepressant discontinuation syndrome include flu-like symptoms, insomnia, ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0801/p449.html

Antidepressant Medications in Pregnancy - FPIN's Clinical Inquiries - American Family ...

Dec 1, 2004 - Selective serotonin reuptake inhibitors (SSRIs) are considered first-line agents for the treatment of depression in pregnant women. SSRIs and tricyclic antidepressants (TCAs) are considered safe and effective in pregnant women, although some studies have indicated increased short-term ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2004/1201/p2195.html

Antidepressant Use During Pregnancy - FPIN's Clinical Inquiries - American Family ...

May 15, 2011 - There are no studies that have shown any antidepressant to be absolutely safe for use during any stage of pregnancy. The use of selective serotonin reuptake inhibitors (SSRIs) or tricyclic antidepressants (TCAs) during pregnancy does not increase the risk of congenital malformations or ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2011/0515/p1211.html

Antidepressants and Antiepileptic Drugs for Chronic Non-Cancer Pain - American Family ...

Feb 1, 2005 - The development of newer classes of antidepressants and second-generation antiepileptic drugs has created unprecedented opportunities for the treatment of chronic pain. These drugs modulate pain transmission by interacting with specific neurotransmitters and ion channels. The actions of...

American Family Physician : Article

https://www.aafp.org/afp/2005/0201/p483.html

Antidepressants and Psychological Therapies Are Effective for IBS - POEMs - American ...

Jan 15, 2015 - Antidepressants and psychological therapies are effective in treating the symptoms of IBS. This study, an update of a similar systematic review and meta-analysis completed five years ago, found the same level of effectiveness for both treatment approaches as the previous analysis, ...

American Family Physician : POEMs

https://www.aafp.org/afp/2015/0115/p134.html

Antidepressants and Smoking Cessation - Cochrane for Clinicians - American Family ...

Jan 1, 2005 - Bupropion and nortriptyline increase the likelihood of smoking cessation, but selective serotonin reuptake inhibitors (SSRIs) do not.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/0101/p67.html

Antidepressants for Agitation and Psychosis in Patients with Dementia - Cochrane for ...

Jan 1, 2012 - There are few high-quality studies examining the effectiveness of antidepressants for treating the neuropsychiatric symptoms of dementia. Although there is some evidence to support the use of the selective serotonin reuptake inhibitors (SSRIs) sertraline (Zoloft) and citalopram ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2012/0101/p20.html

Antidepressants for Generalized Anxiety Disorder - Cochrane for Clinicians - American ...

Nov 1, 2003 - As a group, antidepressants are an effective short-term treatment for GAD. Compared with placebo, about five to six patients must be treated to get one additional patient who responds to therapy. Side effects occur more frequently with antidepressants than with placebo, but they are not...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2003/1101/p1757.html

Antidepressants for Initial Treatment of Depression - AFP Journal Club - American ...

May 15, 2010 - Which antidepressants should be used for the initial treatment of depression? This quality multiple-treatment meta-analysis gives physicians a good starting point for choosing an antidepressant. Sertraline and escitalopram should be considered first-line agents whereas bupropion, ...

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2010/0515/p1205.html

Antidepressants for the Treatment of Insomnia in Patients with Depression - FPIN's ...

Nov 1, 2011 - There is no single antidepressant or class of antidepressants that is most effective for the treatment of insomnia in patients with depression. The use of antidepressant medications can have a positive impact on sleep physiology, but does not seem to improve subjective ratings of sleep ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2011/1101/od1.html

Antidepressants for the Treatment of Neuropathic Pain - Cochrane for Clinicians - ...

Jun 1, 2006 - Tricyclic antidepressants, particularly amitriptyline, are effective for the treatment of painful diabetic neuropathy and post herpetic neuralgia, and may be beneficial in other neuropathic pain syndromes, but they should be used with caution in patients at increased risk of adverse ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/0601/p1933.html

Antidepressants in Older Persons - Cochrane for Clinicians - American Family Physician

Nov 1, 2006 - In older persons with depression, three classes of antidepressants are equally effective: selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants, and tricyclic-like compounds. More patients taking classic tricyclic antidepressants stopped their medications because of...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/1101/p1503.html

Antidepressants Plus Benzodiazepines for Adults with Major Depression - Cochrane for ... Restricted content. Login required.

May 1, 2020 - A combination of tricyclic antidepressants and benzodiazepines is more effective for major depression in adults than tricyclic antidepressants alone in the first four weeks of treatment.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2020/0501/p527.html

Antidepressants to Treat Nonspecific Low Back Pain - Cochrane for Clinicians - American...

Jul 1, 2008 - Although antidepressants have been shown to be superior to placebo in some forms of chronic pain, they do not reduce pain or improve functional status or depression in patients with nonspecific low back pain.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2008/0701/p51.html

Antidepressants: Update on New Agents and Indications - American Family Physician

Feb 1, 2003 - A number of antidepressants have emerged in the U.S. market in the past two decades. Selective serotonin reuptake inhibitors have become the drugs of choice in the treatment of depression, and they are also effective in the treatment of obsessive-compulsive disorder, panic disorder, and...

American Family Physician : Article

https://www.aafp.org/afp/2003/0201/p547.html

Antiemetics for Acute Gastroenteritis in Children - FPIN's Clinical Inquiries - ... Restricted content. Login required.

Jul 1, 2020 - Oral ondansetron (Zofran) may be given to children presenting to the emergency department with vomiting and mild to moderate dehydration from acute gastroenteritis. It reduces hospital admissions and the need for intravenous hydration.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2020/0701/p51.html

Antiepileptic Drug Level Monitoring - FPIN's Clinical Inquiries - American Family ...

Aug 1, 2008 - Routine monitoring of antiepileptic drug levels does not alter seizure or side effect rates.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2008/0801/p385.html

Antiepileptic Drug Monotherapy for Epilepsy - Cochrane for Clinicians - American Family...

May 1, 2018 - In patients with partial-onset (focal) seizures, levetiracetam (Keppra), lamotrigine (Lamictal), and carbamazepine (Tegretol) were associated with the longest time to treatment withdrawal (i.e., the recommended patient-oriented outcome measure that balances tolerability with ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2018/0501/p572.html

Antiepileptic Drugs After First Unprovoked Seizure - Medicine by the Numbers - American...

Feb 1, 2017 - The decision to start an antiepileptic drug after a first unprovoked seizure has long been a clinically challenging one.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2017/0201/od1.html

Antihistamines for the Common Cold - Cochrane for Clinicians - American Family Physician

Aug 1, 2004 - Antihistamines are of minimal to no benefit as mono-therapy for the common cold, and first-generation antihistamines may increase sedation in patients with a cold. Antihistamine-decongestant combinations reduce nasal symptoms and improve the recovery rate in older children and adults, ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2004/0801/p486.html

Antihypertensive Drug Therapy for Mild to Moderate Hypertension During Pregnancy - ...

Oct 1, 2019 - Compared with placebo, antihypertensive drug therapy for mild to moderate hypertension (defined by the authors as a blood pressure of 140 to 169 mm Hg systolic or 90 to 109 mm Hg diastolic) caused by chronic hypertension, gestational hypertension, or preeclampsia during pregnancy does ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/1001/p403.html

Antimicrobial Resistence: A Plan of Action for Community Practice - American Family ...

Mar 15, 2001 - Antibiotic resistance was once confined primarily to hospitals but is becoming increasingly prevalent in family practice settings, making daily therapeutic decisions more challenging. Recent reports of pediatric deaths and illnesses in communities in the United States have raised ...

American Family Physician : Article

https://www.aafp.org/afp/2001/0315/p1087.html

Antioxidant Supplements Do Not Improve Mortality and May Cause Harm - Cochrane for ...

Nov 1, 2008 - In randomized controlled trials of primary and secondary prevention, vitamins A and E, and beta-carotene supplementation increased mortality. Vitamin C and selenium supplementation had no significant effect on mortality.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2008/1101/p1079.html

Antioxidants and Minerals for Age-Related Macular Degeneration - Cochrane for ...

Sep 1, 2006 - Supplementation with a combination of vitamin C, vitamin E, beta-carotene, and zinc modestly reduces the progression of ARMD in patients with disease in one or both eyes. High-dose vitamin supplements should not be recommended for patients without ARMD because of the possible harmful ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/0901/p750.html

Antiplatelet Therapy and Anticoagulation in Patients with Hypertension - Cochrane for ...

Mar 1, 2005 - Antiplatelet agents should not be used in patients with hypertension and no previous history of heart attack or stroke. However, these agents are recommended for use in hypertensive patients who already have vascular disease. Anticoagulants should not be used for prevention of vascular ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/0301/p897.html

Antiplatelet vs. Anticoagulation Therapy for Patients with Heart Failure in Sinus ...

Aug 1, 2017 - Heart failure increases the risk of thrombotic complications, but use of warfarin does not lower all-cause mortality more than aspirin in patients with heart failure with reduced ejection fraction in sinus rhythm.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2017/0801/p160.html

Antipsychotics for Fibromyalgia in Adults - Medicine by the Numbers - American Family ...

Aug 1, 2017 - Quetiapine may be considered for a limited period (less than 12 weeks) to improve pain, sleep, and depression in fibromyalgia, while considering the potential for weight gain.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2017/0801/od1.html

Antipsychotics Worsen Symptoms in Patients with Delirium Who Receive Palliative Care - ...

Mar 15, 2017 - For hospitalized patients with acute delirium and symptoms of distress who are receiving palliative care, the use of risperidone (Risperdal) or haloperidol at conservative oral doses worsens symptoms and may shorten overall survival.

American Family Physician : POEMs

https://www.aafp.org/afp/2017/0315/od3.html

Antiretroviral Therapy to Prevent Transmission in HIV-Discordant Couples - Cochrane for...

Mar 1, 2012 - Rates of HIV transmission are at least three times lower in HIV-discordant couples in which the partner with infection is receiving antiretroviral therapy, compared with HIV-discordant couples in which the partner with infection is not receiving therapy. Among HIV-discordant couples in ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2012/0301/p445.html

Antiviral Agents for Pregnant Women with Genital Herpes - FPIN's Clinical Inquiries - ...

Nov 1, 2005 - There is no evidence that the use of antiviral agents in women who are pregnant and have a history of genital herpes prevents perinatal transmission of herpes simplex virus (HSV) to neonates.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2005/1101/p1807.html

Antiviral Drugs in Healthy Children - American Family Physician

Mar 1, 1998 - Several antiviral agents are available to treat viral illnesses in healthy children. In some children, treatment with acyclovir is an alternative to vaccination for the treatment and prevention of chickenpox. Acyclovir also can be useful in the treatment or prevention of herpes simplex ...

American Family Physician : Article

https://www.aafp.org/afp/1998/0301/p1073.html

Antiviral Drugs in the Immunocompetent Host: Part I. Treatment of Hepatitis, ...

Feb 15, 2003 - Advertisement << Previous article Next article >> Feb 15, 2003 Issue Antiviral Drugs in the Immunocompetent Host: Part I. Treatment of Hepatitis, Cytomegalovirus, and Herpes Infections RICHARD COLGAN, M.D., University of Maryland School of Medicine, Baltimore, Maryland ROBERT...

American Family Physician : Article

https://www.aafp.org/afp/2003/0215/p757.html

Antiviral Drugs in the Immunocompetent Host: Part II. Treatment of Influenza and ...

Feb 15, 2003 - Family physicians should be familiar with the various drugs available for treating and preventing viral infections. Part II of this two-part article focuses on agents used to manage influenza and respiratory syncytial virus. Rimantadine and amantadine traditionally have been used to ...

American Family Physician : Article

https://www.aafp.org/afp/2003/0215/p763.html

Antiviral Therapy for Bell Palsy - Cochrane for Clinicians - American Family Physician

May 1, 2016 - The combination of antiviral agents and corticosteroids is more effective than corticosteroids alone for the complete recovery of patients with Bell palsy (number needed to treat [NNT] = 15) and for the resolution of motor synkinesis and excessive tear production (NNT = 12). Antivirals ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2016/0501/p742.html

APA Releases Guidelines on Treating Obsessive-Compulsive Disorder - Practice Guidelines...

Jul 1, 2008 - In 2007, the American Psychiatric Association (APA) published treatment recommendations for obsessive-compulsive disorder (OCD). Management of OCD can involve many therapeutic actions depending on the needs, capacities, and desires of the patient.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2008/0701/p131.html

APA Releases Guidelines on Treatment of Patients with Major Depressive Disorder - ...

May 15, 2011 - The American Psychiatric Association (APA) recently updated its guideline on the treatment of major depressive disorder. The new evidence-based guideline summarizes recommendations on the use of antidepressants and other drug therapies; psychotherapy, including cognitive behavior ...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2011/0515/p1219.html

Appendicitis - Clinical Evidence Handbook - American Family Physician

Jan 15, 2016 - What are the effects of surgery compared with antibiotics for acute appendicitis?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2016/0115/p142.html

Appetite Suppressants as Adjuncts for Weight Loss - FPIN's Clinical Inquiries - ...

Apr 1, 2011 - Phentermine and diethylpropion are appetite suppressants approved for use in the United States as adjuncts in the treatment of obesity. These agents demonstrate a modest weight loss benefit when combined with dietary modifications and exercise.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2011/0401/od1.html

Approach to Vaso-occlussive Crisis in Adults with Sickle Cell Disease - American Family...

Mar 1, 2000 - The vaso-occlusive crisis, or sickle cell crisis, is a common painful complication of sickle cell disease in adolescents and adults. Acute episodes of severe pain (crises) are the primary reason that these patients seek medical care in hospital emergency departments. Frequently, ...

American Family Physician : Article

https://www.aafp.org/afp/2000/0301/p1349.html

Approaching the Suicidal Patient - American Family Physician

Nov 1, 2003 - The suicide of a patient can be devastating to the family and to the family physician. The patient's death may shake the physician's confidence, undermine any willingness to work with patients with a mental illness, and provoke professional and legal review. In an attempt to help the ...

American Family Physician : Article

https://www.aafp.org/afp/2003/1101/p1814.html

Appropriate Antibiotic Use: Family Physicians Have the Power of the Pen - Editorials - ...

Nov 1, 2012 - Visits for acute URIs account for more than one-half of all antibiotic prescriptions for outpatients, and these infections lead to more unnecessary and inappropriate antibiotic prescriptions than any other infectious syndrome.

American Family Physician : Editorials

https://www.aafp.org/afp/2012/1101/p810.html

Appropriate Antimicrobial Prescribing: Approaches that Limit Antibiotic Resistance - ...

Sep 15, 2001 - Since the introduction of antimicrobial agents, there has been an association between antibiotic use and the development of antimicrobial resistance. Antibiotic therapy eradicates not only pathogenic organisms but also the protective normal flora. This so-called

American Family Physician : Article

https://www.aafp.org/afp/2001/0915/p999.html

Appropriate Prescribing of Medications: An Eight-Step Approach - American Family Physician

Jan 15, 2007 - A systematic approach advocated by the World Health Organization can help minimize poor-quality and erroneous prescribing. This six-step approach to prescribing suggests that the physician should (1) evaluate and dearly define the patient's problem; (2) specify the therapeutic ...

American Family Physician : Article

https://www.aafp.org/afp/2007/0115/p231.html

Appropriate Prescribing of Oral Beta-Lactam Antibiotics - American Family Physician

Aug 1, 2000 - Beta-lactam antibiotics include penicillins, cephalosporins and related compounds. As a group, these drugs are active against many gram-positive, gram-negative and anaerobic organisms. Information based on

American Family Physician : Article

https://www.aafp.org/afp/2000/0801/p611.html

Appropriate Use of Antibiotics for URIs in Children: Part I. Otitis Media and Acute ...

Oct 1, 1998 - Five conditions--otitis media, acute sinusitis, cough, pharyngitis and the common cold--account for most of the outpatient use of antibiotics in the United States. The first part of this two-part article presents guidelines that encourage physicians to make an appropriate distinction ...

American Family Physician : Article

https://www.aafp.org/afp/1998/1001/p1113.html

Appropriate Use of Antibiotics for URIs in Children: Part II. Cough, Pharyngitis and ...

Oct 15, 1998 - This article summarizes the principles of judicious antimicrobial therapy for three of the five conditions--cough, pharyngitis, the common cold--that account for most of the outpatient use of these drugs in the United States. The principles governing the other two conditions, otitis ...

American Family Physician : Article

https://www.aafp.org/afp/1998/1015/p1335.html

Appropriate Use of Opioids for Chronic Pain - Lown Right Care: Reducing Overuse and ... Restricted content. Login required.

Sep 15, 2020 - A collaboration between AFP and the Lown Institute promotes a vision of delivering health care that is based on the evidence, balanced in its approach, and focused on the patient.

American Family Physician : Lown Right Care: Reducing Overuse and Underuse

https://www.aafp.org/afp/2020/0915/p335.html

Appropriate Use of Polypharmacy for Older Patients - Cochrane for Clinicians - American...

Apr 1, 2013 - Multidisciplinary interventions that address polypharmacy decrease inappropriate prescribing and medication-related problems in patients 65 years and older, but it is not clear if they reduce hospital admissions or improve quality of life. Most interventions studied were led by ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/0401/p483.html

Appropriate Use of Psychotropic Drugs in Nursing Homes - American Family Physician

Mar 1, 2000 - The Omnibus Budget Reconciliation Act (OBRA) of 1987 limited the use of psychotropic medications in residents of long-term care facilities. Updates of OBRA guidelines have liberalized some dosing restrictions, but documentation of necessity and periodic trials of medication withdrawal ...

American Family Physician : Article

https://www.aafp.org/afp/2000/0301/p1437.html

Appropriate Use of the Intrauterine Device - American Family Physician

Dec 1, 1998 - The intrauterine device, a common form of birth control in the early 1970s, is now avoided by American physicians and women because of concern about complications. This concern is largely the result of the problems reported with use of an intrauterine device that is no longer ...

American Family Physician : Article

https://www.aafp.org/afp/1998/1201/p2077.html

Are Alpha-glucosidase Inhibitors Effective for Control of Type 2 Diabetes? - Cochrane ...

Feb 1, 2006 - The use of alpha-glucosidase inhibitors has a modest effect on intermediate diabetes-control endpoints such as postprandial blood glucose, postprandial insulin levels, and A1C levels. There is no evidence, however, of improvement in mortality, morbidity, or quality of life. In ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/0201/p433.html

Are Anticoagulants Better than Antiplatelet Agents for Treatment of Acute Ischemic ...

Oct 1, 2003 - Aspirin has a small benefit for long-term outcome and survival. Anticoagulants increase the risk for bleeding and do not have long-term benefit.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2003/1001/p1307.html

Are Atypical Antipsychotics Safe in Patients with Alzheimer's Disease? - Cochrane for ...

Aug 1, 2006 - Although the atypical antipsychotic medications risperidone (Risperdal) and olanzapine (Zyprexa) are modestly efficacious in reducing aggression, routine use is not justified. Both drugs are associated with serious adverse cerebrovascular events and extrapyramidal symptoms. Use of ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/0801/p414.html

Are Beta Blockers Effective First-line Treatments for Hypertension? - Cochrane for ...

Nov 1, 2007 - Current evidence does not support the use of beta blockers as initial therapy for hypertension.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/1101/p1306.html

Are Cranberry Products Effective for the Prevention of Urinary Tract Infections? - ...

Dec 1, 2013 - Cranberry products are not effective and should not be recommended for the prevention of UTIs.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/1201/p745.html

Are Long-acting Insulin Analogues Better Than Isophane Insulin? - Cochrane for ...

Feb 15, 2008 - Based on poor quality evidence, this review suggests that insulin glargine and insulin detemir have no advantage over isophane insulin in reducing A1C levels. In one study, isophane insulin reduced A1C levels slightly more than insulin detemir. However, patients on insulin glargine and ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2008/0215/p447.html

Are Low-Fat Diets Better than Other Weight-Reducing Diets in Achieving Long-Term Weight...

Feb 1, 2003 - Low-fat diets are no better than low-calorie diets in achieving weight loss in overweight or obese people. In studies, the average weight loss after 18 months on either diet was less than 5 lb.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2003/0201/p507.html

Are Metered-Dose Inhalers with Holding Chambers Better Than Nebulizers for Treating ...

Jan 1, 2003 - In the emergency room, MDIs with holding chambers are as effective as nebulizers for delivering beta2 agonists to treat acute asthma in adults and children older than age two. There might be slightly less beta2 agonist–induced tachycardia in children when MDIs with holding chambers are ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2003/0101/p62.html

Are Neuraminidase Inhibitors Effective for Preventing and Treating Influenza in Healthy...

Oct 1, 2012 - Treating previously healthy patients with oseltamivir (Tamiflu) reduces the duration of influenza symptoms by approximately 21 hours, but it does not reduce the risk of hospitalization in this population.1 The data are insufficient to determine whether oseltamivir reduces the ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2012/1001/p624.html

Are Opioids Effective in the Treatment of Neuropathic Pain? - Cochrane for Clinicians -...

Apr 1, 2007 - Eight to 60 days of opioid therapy for the treatment of neuropathic pain effectively reduces pain scores as measured by a visual analog scale. A lack of response to opioids in the first 24 hours should not be used to predict whether longer-term opioid therapy might be beneficial. There ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0401/p999.html

Are Oral Betamimetics Effective Maintenance Therapies After Threatened Preterm Labor? -...

Mar 1, 2007 - There is no evidence to support the use of oral betamimetics for maintenance therapy after treatment for threatened preterm labor, and there is a risk of adverse effects with these drugs.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0301/p648.html

Are Selective COX-2 Inhibitors as Effective as NSAIDs in Patients with Rheumatoid ...

Feb 1, 2004 - The efficacy of COX-2 inhibitors is similar to that of nonselective NSAIDs in reducing the symptoms of rheumatoid arthritis.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2004/0201/p595.html

Are Some Antidepressants Safer than Others Regarding Suicide Risk? - POEMs - American ...

Jul 1, 2015 - Mirtazapine (Remeron) and venlafaxine are associated with higher rates of completed suicide in primary care patients. Rates of suicide attempts and completion are similar with the use of selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants.

American Family Physician : POEMs

https://www.aafp.org/afp/2015/0701/p52a.html

Are SSRIs Effective for Treating OCD? - Cochrane for Clinicians - American Family ...

May 1, 2008 - SSRIs are effective for the treatment of OCD. If it is assumed that 10 percent of persons with OCD will recover without treatment, then 12 persons with OCD need to be treated for one additional person to have a response within six to 13 weeks. If it is assumed that 20 percent of persons...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2008/0501/p1252.html

Are You Talking to Your Patients About CAM? - Editorials - American Family Physician

Aug 1, 2009 - Advertisement << Previous article Next article >> Aug 1, 2009 Issue Editorials Are You Talking to Your Patients About CAM? SUMI SEXTON, MD, Georgetown University Medical Center, Washington, DC Am Fam Physician. 2009 Aug 1;80(3):228-230. In June 2008, the National Center for...

American Family Physician : Editorials

https://www.aafp.org/afp/2009/0801/p228.html

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