Targeted Cancer Therapies - American Family Physician
Feb 1, 2021 - Targeted cancer therapies involve chemotherapeutic agents that attack, directly or indirectly, a specific genetic biomarker found in a given cancer. Targeted oncology includes monoclonal antibodies, small molecule inhibitors, antibody-drug conjugates, and immunotherapy. For example, the...
American Family Physician : Article
https://www.aafp.org/afp/2021/0201/p155.html
Breast Cancer Screening: Common Questions and Answers - American Family Physician
Jan 1, 2021 - Breast cancer is the most common nonskin cancer in women and accounts for 30% of all new cancers in the United States. The highest incidence of breast cancer is in women 70 to 74 years of age. Numerous risk factors are associated with the development of breast cancer. A risk assessment ...
American Family Physician : Article
https://www.aafp.org/afp/2021/0101/p33.html
Colorectal Cancer Screening and Surveillance in Individuals at Increased Risk - ...
Jan 15, 2018 - Individuals at increased risk of developing colorectal cancer include those with a personal or family history of advanced adenomas or colorectal cancer, a personal history of inflammatory bowel disease, or genetic polyposis syndromes. In general, these persons should undergo more ...
American Family Physician : Article
https://www.aafp.org/afp/2018/0115/p111.html
Oncologic Emergencies: Recognition and Initial Management - American Family Physician
Jun 1, 2018 - Most oncologic emergencies can be classified as metabolic, hematologic, structural, or treatment related. Tumor lysis syndrome is a metabolic emergency that presents as severe electrolyte abnormalities. Stabilization is focused on vigorous rehydration, maintaining urine output, and ...
American Family Physician : Article
https://www.aafp.org/afp/2018/0601/p741.html
Cervical Colposcopy: Indications and Risk Assessment - American Family Physician
Jul 1, 2020 - The practice of colposcopy, a diagnostic procedure to evaluate for vaginal, vulvar, and cervical dysplasia, has evolved to incorporate patient risk factors for high-grade cervical intraepithelial neoplasia (CIN) and cancer. Changes in cervical cancer screening and guidelines, human ...
American Family Physician : Article
https://www.aafp.org/afp/2020/0701/p39.html
Basal Cell and Cutaneous Squamous Cell Carcinomas: Diagnosis and Treatment - American ...
Sep 15, 2020 - Keratinocyte carcinoma, traditionally referred to as nonmelanoma skin cancer, includes basal cell and cutaneous squamous cell carcinoma and is the most common skin cancer malignancy found in humans. The U.S. Preventive Services Task Force recommends counseling about minimizing exposure ...
American Family Physician : Article
https://www.aafp.org/afp/2020/0915/p339.html
Cancer - American Family Physician
Mar 1, 2021 - This collection features AFP content on cancer and related issues, including various types (breast, cervical, childhood, colorectal, lung, oral, ovarian, prostate, skin, testicular, and other types of cancer). This collection features AFP content on cancer and related issues, including ...
- General
- Bladder Cancer
- Breast Cancer
- Cervical Cancer
- Childhood Cancers
- Colorectal Cancer
- Esophageal Cancer
- Lung Cancer
- Oral Cancer
- Ovarian Cancer
- Prostate Cancer
- Skin Cancer
- Testicular Cancer
- Other Cancers
- Patient Education, Self-Care
American Family Physician : AFP By Topic
https://www.aafp.org/afp/topicModules/viewTopicModule.htm?topicModuleId=31
Multiple Myeloma: Diagnosis and Treatment - American Family Physician
Mar 15, 2017 - Multiple myeloma accounts for 1.6% of all cancer cases and approximately 10% of hematologic malignancies in the United States. In 2015, an estimated 28,850 new cases of multiple myeloma were diagnosed in the United States, and the disease caused more than 11,000 deaths. Patients older ...
American Family Physician : Article
https://www.aafp.org/afp/2017/0315/p373.html
Delivering Bad or Life-Altering News - American Family Physician
Jul 15, 2018 - Delivering serious, bad, or life-altering news to a patient is one of the most difficult tasks physicians encounter. Broadly defined as information that may alter a patient’s view of his or her future, bad news may include information related to a chronic disease (e.g., diabetes ...
American Family Physician : Article
https://www.aafp.org/afp/2018/0715/p99.html
Cervical Cancer Screening - American Family Physician
Apr 1, 2018 - Screening in women has decreased the incidence and mortality of cervical cancer. Precancerous cervical lesions (cervical intraepithelial neoplasias) and cervical carcinomas are strongly associated with sexually-transmitted high-risk human papillomavirus (HPV) infection, which causes ...
American Family Physician : Article
https://www.aafp.org/afp/2018/0401/p441.html
Lymphoma: Diagnosis and Treatment - American Family Physician
Jan 1, 2020 - Lymphoma is a group of malignant neoplasms of lymphocytes with more than 90 subtypes. It is traditionally classified broadly as non-Hodgkin or Hodgkin lymphoma. Approximately 82,000 new U.S. patients are diagnosed with lymphoma annually. Any tobacco use and obesity are major modifiable ...
American Family Physician : Article
https://www.aafp.org/afp/2020/0101/p34.html
Colorectal Cancer Screening and Surveillance - American Family Physician
Jan 15, 2015 - Colorectal cancer is the third most common cancer in men and women. The incidence and mortality rate of the disease have been declining over the past two decades because of early detection and treatment. Screening in persons at average risk should begin at 50 years of age; the U.S. ...
American Family Physician : Article
https://www.aafp.org/afp/2015/0115/p93.html
Renal Cell Carcinoma: Diagnosis and Management - American Family Physician
Feb 1, 2019 - Kidney cancer is one of the 10 most common cancers in the United States with 90% being attributed to renal cell carcinoma. Men, especially black men, are more likely to be affected than women. Renal masses, either cystic or solid, are best detected with contrast-enhanced, triple-phase ...
American Family Physician : Article
https://www.aafp.org/afp/2019/0201/p179.html
Colorectal Cancer Screening and Prevention - American Family Physician
May 15, 2018 - Colorectal cancer is a common cause of morbidity and mortality in the United States. Most colorectal cancers arise from preexisting adenomatous or serrated polyps. The incidence and mortality of colorectal cancer can be reduced with screening of average-risk adults 50 to 75 years of ...
American Family Physician : Article
https://www.aafp.org/afp/2018/0515/p658.html
Bone Cancer: Diagnosis and Treatment Principles - American Family Physician
Aug 15, 2018 - Primary bone cancers include osteosarcoma, Ewing sarcoma, and chondrosarcoma. They account for less than 1% of diagnosed cancers each year and are associated with significant morbidity and mortality. Timely diagnosis is challenging because of late patient presentation, nonspecific ...
American Family Physician : Article
https://www.aafp.org/afp/2018/0815/p205.html
Atypical Moles: Diagnosis and Management - American Family Physician
Jun 1, 2015 - Atypical moles are benign pigmented lesions. Although they are benign, they exhibit some of the clinical and histologic features of malignant melanoma. They are more common in fair-skinned individuals and in those with high sun exposure. Atypical moles are characterized by size of 6 mm ...
American Family Physician : Article
https://www.aafp.org/afp/2015/0601/p762.html
Testicular Cancer: Diagnosis and Treatment - American Family Physician
Feb 15, 2018 - Testicular cancer is the most common solid tumor among males 15 to 34 years of age, with an estimated 8,850 new cases and 410 deaths during 2017 in the United States. With effective treatment, the overall five-year survival rate is 97%. Risk factors for testicular cancer include ...
American Family Physician : Article
https://www.aafp.org/afp/2018/0215/p261.html
Bladder Cancer: Diagnosis and Treatment - American Family Physician
Oct 15, 2017 - Bladder cancer is the sixth most prevalent malignancy in the United States and causes more than 16,000 deaths annually. The most common clinical presentation is asymptomatic hematuria, which should prompt evaluation with cystoscopy, renal function testing, and upper urinary tract ...
American Family Physician : Article
https://www.aafp.org/afp/2017/1015/p507.html
Primary Care of Breast Cancer Survivors - American Family Physician
Mar 15, 2019 - With declining mortality rates, the number of breast cancer survivors is increasing. Ongoing care after breast cancer treatment is often provided by primary care physicians. This care includes surveillance for cancer recurrence with a history and physical examination every three to six ...
American Family Physician : Article
https://www.aafp.org/afp/2019/0315/p370.html
Diagnosis and Management of Adnexal Masses - American Family Physician
Apr 15, 2016 - Adnexal masses can have gynecologic or nongynecologic etiologies, ranging from normal luteal cysts to ovarian cancer to bowel abscesses. Women who report abdominal or pelvic pain, increased abdominal size or bloating, difficulty eating, or rapid satiety that occurs more than 12 times ...
American Family Physician : Article
https://www.aafp.org/afp/2016/0415/p676.html
Cervical Cancer: Evaluation and Management - American Family Physician
Apr 1, 2018 - Human papillomavirus infection is the precursor for the development of cervical cancer and is detectable in 99.7% of squamous cell carcinoma and adenocarcinoma cases. Early detection of precancerous lesions with Papanicolaou testing remains the primary mechanism for cancer prevention. ...
American Family Physician : Article
https://www.aafp.org/afp/2018/0401/p449.html
Localized Prostate Cancer: Treatment Options - American Family Physician
Jun 15, 2018 - In the United States, prostate cancer will be diagnosed in one out of seven men in his lifetime. Most cases are localized, and only one in 39 men will die from the disease. Prostate cancer is most often detected using serum prostate-specific antigen testing. The National Comprehensive ...
American Family Physician : Article
https://www.aafp.org/afp/2018/0615/p798.html
Diagnosis and Management of Endometrial Cancer - American Family Physician
Mar 15, 2016 - Endometrial cancer is the most common gynecologic malignancy. It is the fourth most common cancer in women in the United States after breast, lung, and colorectal cancers. Risk factors are related to excessive unopposed exposure of the endometrium to estrogen, including unopposed ...
American Family Physician : Article
https://www.aafp.org/afp/2016/0315/p468.html
Esophageal Cancer - American Family Physician
Jan 1, 2017 - Esophageal cancer has a poor prognosis and high mortality rate, with an estimated 16,910 new cases and 15,910 deaths projected in 2016 in the United States. Squamous cell carcinoma and adenocarcinoma account for more than 95% of esophageal cancers. Squamous cell carcinoma is more common...
American Family Physician : Article
https://www.aafp.org/afp/2017/0101/p22.html
Diagnosis and Management of Ovarian Cancer - American Family Physician
Jun 1, 2016 - Ovarian cancer is the most lethal gynecologic cancer. Less than one-half of patients survive for more than five years after diagnosis. Ovarian cancer affects women of all ages but is most commonly diagnosed after menopause. More than 75% of affected women are diagnosed at an advanced ...
American Family Physician : Article
https://www.aafp.org/afp/2016/0601/p937.html
Primary Brain Tumors in Adults: Diagnosis and Treatment - American Family Physician
Feb 1, 2016 - Primary intracranial tumors of the brain structures, including meninges, are rare with an overall five-year survival rate of 33.4%; they are collectively called primary brain tumors. Proven risk factors for these tumors include certain genetic syndromes and exposure to high-dose ...
American Family Physician : Article
https://www.aafp.org/afp/2016/0201/p211.html
Lung Cancer: Diagnosis, Treatment Principles, and Screening - American Family Physician
Feb 15, 2015 - Lung cancer is classified histologically into small cell and non–small cell lung cancers. The most common symptoms of lung cancer are cough, dyspnea, hemoptysis, and systemic symptoms such as weight loss and anorexia. High-risk patients who present with symptoms should undergo chest ...
American Family Physician : Article
https://www.aafp.org/afp/2015/0215/p250.html
Care of the Colorectal Cancer Survivor - American Family Physician
Mar 1, 2018 - Colorectal cancer is the fourth most common cancer in the United States and has a five-year survival rate of 65%. The American Cancer Society and other experts have released guidelines on surveillance, health promotion, screening for other malignancies, and management of treatment ...
American Family Physician : Article
https://www.aafp.org/afp/2018/0301/p331.html
Leukemia: An Overview for Primary Care - American Family Physician
May 1, 2014 - Leukemia is a clonal proliferation of hematopoietic stem cells in the bone marrow. The four broad subtypes most likely to be encountered by primary care physicians are acute lymphoblastic, acute myelogenous, chronic lymphocytic, and chronic myelogenous. Acute lymphoblastic leukemia ...
American Family Physician : Article
https://www.aafp.org/afp/2014/0501/p731.html
Signs and Symptoms of Childhood Cancer: A Guide for Early Recognition - American Family...
Aug 1, 2013 - Although cancer in children is rare, it is the second most common cause of childhood mortality in developed countries. It often presents with nonspecific symptoms similar to those of benign conditions, leading to delays in the diagnosis and initiation of appropriate treatment. Primary ...
American Family Physician : Article
https://www.aafp.org/afp/2013/0801/p185.html
Prostate Cancer Screening - American Family Physician
Oct 15, 2015 - Among American men, prostate cancer is the most commonly diagnosed cancer and the second leading cause of cancer-related death. Although prostate-specific antigen (PSA) testing has been used to screen for prostate cancer for more than 25 years, the test has low sensitivity and ...
American Family Physician : Article
https://www.aafp.org/afp/2015/1015/p683.html
Cancer Screening in Older Patients - American Family Physician
Apr 15, 2016 - Although cancer is the second leading cause of death among persons 65 years and older, there is a paucity of clinical trial data about the effectiveness and harms of cancer screening in this population. Given the heterogeneous nature of the older population, cancer screening in these ...
American Family Physician : Article
https://www.aafp.org/afp/2016/0415/p659.html
Primary Care of the Prostate Cancer Survivor - American Family Physician
May 1, 2016 - This summary of the American Cancer Society Prostate Cancer Survivorship Care Guidelines targets primary care physicians who coordinate care of prostate cancer survivors with subspecialists. Prostate cancer survivors should undergo prostate-specific antigen screening every six to 12 ...
American Family Physician : Article
https://www.aafp.org/afp/2016/0501/p764.html
Diagnosis and Management of Pancreatic Cancer - American Family Physician
Apr 15, 2014 - Pancreatic cancer remains the fourth leading cause of cancer-related deaths in the United States. Risk factors include family history, smoking, chronic pancreatitis, obesity, diabetes mellitus, heavy alcohol use, and possible dietary factors. Because more than two-thirds of ...
American Family Physician : Article
https://www.aafp.org/afp/2014/0415/p626.html
Screening for Cancer: Concepts and Controversies - American Family Physician
Nov 1, 2014 - Early detection of cancer is a core task in family medicine, and patients have come to expect screening tests, sometimes out of proportion to what evidence can justify. To understand the controversies surrounding screening and to provide sound advice to patients, family physicians ...
American Family Physician : Article
https://www.aafp.org/afp/2014/1101/p625.html
Surveillance of the Adult Cancer Survivor - American Family Physician
Jan 1, 2015 - The term cancer survivor refers to anyone living with a diagnosis of cancer. As the U.S. population ages, cancer screening increases, and cancer treatments improve, millions more Americans will be classified as cancer survivors in the future. Although many survivors wish to continue ...
American Family Physician : Article
https://www.aafp.org/afp/2015/0101/p29.html
Common Questions About Barrett Esophagus - American Family Physician
Jan 15, 2014 - Barrett esophagus is a precancerous metaplasia of the esophagus that is more common in patients with chronic reflux symptoms, although it also occurs in patients without symptomatic reflux. Other risk factors include smoking, male sex, obesity, white race, hiatal hernia, and increasing ...
American Family Physician : Article
https://www.aafp.org/afp/2014/0115/p92.html
Breast Cancer Screening Update - American Family Physician
Feb 15, 2013 - Breast cancer is the most common non–skin cancer and the second leading cause of cancer death in North American women. Mammography is the only screening test shown to reduce breast cancer–related mortality. There is general agreement that screening should be offered at least biennially ...
American Family Physician : Article
https://www.aafp.org/afp/2013/0215/p274.html
Treatment of Breast Cancer - American Family Physician
Jun 1, 2010 - Understanding breast cancer treatment options can help family physicians care for their patients during and after cancer treatment. This article reviews typical treatments based on stage, histology, and biomarkers. Lobular carcinoma in situ does not require treatment. Ductal carcinoma ...
American Family Physician : Article
https://www.aafp.org/afp/2010/0601/p1339.html
Colonoscopy Follow-up: U.S. Multi-Society Task Force on Colorectal Cancer Updates ...
Mar 1, 2021 - Screening colonoscopy findings define the future risk of colorectal cancer and the need for repeat screening. The U.S. Multi-Society Task Force on Colorectal Cancer updated recommended follow-up intervals after screening colonoscopy in average-risk individuals.
American Family Physician : Practice Guidelines
https://www.aafp.org/afp/2021/0301/p314.html
Cutaneous Malignant Melanoma: A Primary Care Perspective - American Family Physician
Jan 15, 2012 - Cutaneous malignant melanoma accounts for 3 to 5 percent of all skin cancers and is responsible for approximately 75 percent of all deaths from skin cancer. Persons with an increased number of moles, dysplastic (also called atypical) nevi, or a family history of the disease are at ...
American Family Physician : Article
https://www.aafp.org/afp/2012/0115/p161.html
Update on ASCCP Consensus Guidelines for Abnormal Cervical Screening Tests and Cervical...
Jul 15, 2009 - New data have emerged since publication of the American Society for Colposcopy and Cervical Pathology's 2001 consensus guidelines for management of abnormal cervical cytology and histology. The 2006 guidelines include recommendations for special populations (i.e., adolescents and ...
American Family Physician : Article
https://www.aafp.org/afp/2009/0715/p147.html
Colorectal Cancer Screening: ACP Guidance Statements - Practice Guidelines - American ...
Aug 15, 2020 - The American College of Physicians developed a consensus statement for colorectal cancer screening of average-risk adults based on their review of six independent guidelines and supporting evidence.
American Family Physician : Practice Guidelines
https://www.aafp.org/afp/2020/0815/p250.html
Screening for Cervical Intraepithelial Neoplasia with Patient-Collected HPV Samples - ...
Feb 1, 2021 - How useful are patient-collected human papillomavirus vaginal swabs as a screening test for cervical intraepithelial neoplasia?
American Family Physician : FPIN's Clinical Inquiries
https://www.aafp.org/afp/2021/0201/p181.html
Managing the Adverse Effects of Radiation Therapy - American Family Physician
Aug 15, 2010 - Nearly two thirds of patients with cancer will undergo radiation therapy as part of their treatment plan. Given the increased use of radiation therapy and the growing number of cancer survivors, family physicians will increasingly care for patients experiencing adverse effects of ...
American Family Physician : Article
https://www.aafp.org/afp/2010/0815/p381.html
HPV Vaccine, Especially Before Age 17, Is Associated with a Large Reduction in Invasive...
Mar 1, 2021 - HPV vaccination is associated with a significant reduction in the likelihood of invasive cervical cancer.
American Family Physician : POEMs
https://www.aafp.org/afp/2021/0301/p312.html
CT Colonography for Colorectal Cancer Screening - Diagnostic Tests: What Physicians ...
Jan 1, 2021 - Computed tomography colonography performs well for colorectal cancer screening. Long-term studies are needed to demonstrate its impact on patient morbidity and mortality, as well as to determine the risks, benefits, and costs.
American Family Physician : Diagnostic Tests: What Physicians Need to Know
https://www.aafp.org/afp/2021/0101/p55.html
VTE in Patients with Cancer: Guidelines from the American Society of Clinical Oncology ...
Aug 1, 2020 - The American Society of Clinical Oncology has updated recommendations for the prevention and treatment of venous thromboembolism (VTE) in patients with cancer.
American Family Physician : Practice Guidelines
https://www.aafp.org/afp/2020/0801/p188.html
Twenty-Year Follow-Up of Women's Health Initiative Trials: Lower Breast Cancer ...
Jan 15, 2021 - The cumulative 20-year follow-up report from the Women's Health Initiative hormone therapy trials found significantly lower breast cancer incidence and mortality among postmenopausal women who previously took conjugated equine estrogen (CEE; Premarin) alone (with a prior hysterectomy) ...
American Family Physician : POEMs
https://www.aafp.org/afp/2021/0115/od1.html
Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer: ...
Feb 15, 2020 - The USPSTF recommends that primary care clinicians assess women with a personal or family history of breast, ovarian, tubal, or peritoneal cancer or who have an ancestry associated with breast cancer susceptibility 1 and 2 (BRCA1/2) gene mutations with an appropriate brief familial risk...
American Family Physician : U.S. Preventive Services Task Force
https://www.aafp.org/afp/2020/0215/p233.html
Breast Cancer Screening: ACP Releases Guidance Statements - Practice Guidelines - ...
Feb 1, 2020 - The American College of Physicians reviewed guidelines from other organizations and developed four statements to provide advice to clinicians about breast cancer screening for women who are at average risk.
American Family Physician : Practice Guidelines
https://www.aafp.org/afp/2020/0201/p184.html
Lymphadenopathy and Malignancy - American Family Physician
Dec 1, 2002 - The majority of patients presenting with peripheral lymphadenopathy have easily identifiable causes that are benign or self-limited. Among primary care patients presenting with lymphadenopathy, the prevalence of malignancy has been estimated to be as low as 1.1 percent. The critical ...
American Family Physician : Article
https://www.aafp.org/afp/2002/1201/p2103.html
Immunogenicity of Childhood Vaccines after Pediatric Cancer - FPIN's Clinical Inquiries...
Dec 1, 2020 - Children treated for cancer do not retain full immunity from previous vaccinations; therefore, it is likely beneficial for children who survive cancer to be revaccinated six to 12 months after immunosuppressive therapy.
American Family Physician : FPIN's Clinical Inquiries
https://www.aafp.org/afp/2020/1201/od1.html
Colorectal Cancer Screening: BMJ Rapid Recommendation - Practice Guidelines - American ...
Aug 15, 2020 - Colorectal cancer (CRC) screening recommendations vary because the underlying evidence is low quality, with few screening methods evaluated by randomized trials. The BMJ/MAGIC Group performed a systematic review based on 15-year CRC risk models to compare screening options.
American Family Physician : Practice Guidelines
https://www.aafp.org/afp/2020/0815/p253.html
Keratinocyte Carcinomas: Should We Screen for Them? - Editorials - American Family ...
Sep 15, 2020 - Keratinocyte carcinoma, which includes basal cell and cutaneous squamous cell carcinomas, is common, and the incidence is increasing.
American Family Physician : Editorials
https://www.aafp.org/afp/2020/0915/p330.html
Medication Use to Reduce Risk of Breast Cancer - Putting Prevention into Practice - ...
Mar 15, 2020 - E.F., a 40-year-old woman, comes to your office for a routine gynecologic visit. She is not taking any medications and is generally healthy. She is sexually active, and her last menstrual period started 10 days ago.
American Family Physician : Putting Prevention into Practice
https://www.aafp.org/afp/2020/0315/p373.html
Diagnosis and Treatment of Bladder Cancer - American Family Physician
Oct 1, 2009 - Bladder cancer is the sixth most prevalent malignancy in the United States. The most common type of bladder cancer is urothelial (transitional cell) carcinoma, and cystoscopy remains the mainstay of diagnosis and surveillance. Fluorescence cystoscopy offers improvement in the detection ...
American Family Physician : Article
https://www.aafp.org/afp/2009/1001/p717.html
Recognizing Neoplastic Skin Lesions: A Photo Guide - American Family Physician
Sep 15, 1998 - Malignant lesions of the skin are common. Patients who develop squamous cell carcinoma and malignant melanoma often have recognizable precursor conditions. A few skin lesions resemble malignancies. Lesions that are growing, spreading or pigmented, or those that occur on exposed areas of...
American Family Physician : Article
https://www.aafp.org/afp/1998/0915/p873.html
Mailing gFOBT or FIT Directly to Patients Increases Uptake of Colorectal Cancer ...
Jul 15, 2020 - Mailed outreach significantly increases rates of colorectal cancer screening, with four tests needing to be mailed to screen one person.
American Family Physician : POEMs
https://www.aafp.org/afp/2020/0715/p117.html
PAULA’s Test for Lung Cancer Screening - Diagnostic Tests: What Physicians Need to Know...
Jul 1, 2020 - Because of insufficient evidence of benefit, no recommendations can be made regarding PAULA's test. Prospective cohort studies of a screening population and randomized controlled trials comparing cancer mortality outcomes using PAULA's test vs. low-dose CT and no screening are needed ...
American Family Physician : Diagnostic Tests: What Physicians Need to Know
https://www.aafp.org/afp/2020/0701/p53.html
Supplemental MRI Screening in Women with Very Dense Breasts Reduces Interval Cancer ...
Jun 1, 2020 - Supplemental MRI screening for women with very dense breasts compared with mammography alone every two years significantly reduces the likelihood of an interval cancer, from 5 per 1,000 to 2.5 per 1,000 in the intention-to-treat population and to 0.8 per 1,000 in the per-protocol ...
American Family Physician : POEMs
https://www.aafp.org/afp/2020/0601/p695a.html
Medication Use to Reduce Risk of Breast Cancer: Recommendation Statement - U.S. ...
Mar 15, 2020 - The USPSTF recommends that clinicians offer to prescribe risk-reducing medications, such as tamoxifen, raloxifene, or aromatase inhibitors, to women who are at increased risk for breast cancer and at low risk for adverse medication effects.
American Family Physician : U.S. Preventive Services Task Force
https://www.aafp.org/afp/2020/0315/od1.html
Endometrial Cancer - American Family Physician
Nov 15, 2009 - Endometrial cancer is the leading cause of gynecologic cancer in the United States. Etiologically, endometrial carcinoma usually results from unopposed estrogen stimulation of the endometrium, although non-estrogen-related forms occur as well. The most common presentation of endometrial...
American Family Physician : Article
https://www.aafp.org/afp/2009/1115/p1075.html
Megestrol for Palliative Care in Patients with Cancer - FPIN's Clinical Inquiries - ...
May 1, 2020 - Megestrol may be considered as a component of palliative care nutritional support in patients with cancer.
American Family Physician : FPIN's Clinical Inquiries
https://www.aafp.org/afp/2020/0501/od1.html
Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer - ...
Feb 15, 2020 - A 31-year-old woman presents to your office for a well-woman examination. She is sexually active in a monogamous relationship and has never been pregnant. She tells you that her mother was diagnosed with tubal cancer at age 40 and that her sister, who is 42 years of age, was recently ...
American Family Physician : Putting Prevention into Practice
https://www.aafp.org/afp/2020/0215/p239.html
Integrating Breast Cancer Risk Management into Primary Care - Editorials - American ...
Mar 15, 2020 - It is important that primary care physicians have the ability and resources to identify women eligible for genetic counseling and testing for breast cancer.
American Family Physician : Editorials
https://www.aafp.org/afp/2020/0315/p330.html
Results of Fecal Immunochemical Tests for Colorectal Cancer Screening Not Affected by ...
Apr 1, 2020 - The use of aspirin, NSAIDs, and oral anticoagulants has no clinically important effects on the positive predictive value of FIT in a screening population.
American Family Physician : POEMs
https://www.aafp.org/afp/2020/0401/p435.html
Screening for Cervical Cancer: Recommendation Statement - U.S. Preventive Services Task...
Feb 15, 2019 - The USPSTF recommends screening for cervical cancer every 3 years with cervical cytology alone in women aged 21 to 29 years. For women aged 30 to 65 years, the USPSTF recommends screening every 3 years with cervical cytology alone, every 5 years with high-risk human papillomavirus ...
American Family Physician : U.S. Preventive Services Task Force
https://www.aafp.org/afp/2019/0215/od1.html
Ovarian Cancer: An Overview - American Family Physician
Sep 15, 2009 - Although ovarian cancer may occur at any age, it is more common in patients older than 50 years. Patients often present with nonspecific pelvic or abdominal symptoms. Initial diagnostic tests include transvaginal ultrasonography and serum cancer antigen 125 measurement; however, these ...
American Family Physician : Article
https://www.aafp.org/afp/2009/0915/p609.html
Multiple Myeloma: Diagnosis and Treatment - American Family Physician
Oct 1, 2008 - Multiple myeloma, the most common bone malignancy, is occurring with increasing frequency in older persons. Typical symptoms are bone pain, malaise, anemia, renal insufficiency, and hypercalcemia. Incidental discovery on comprehensive laboratory panels is common. The disease is ...
American Family Physician : Article
https://www.aafp.org/afp/2008/1001/p853.html
Screening for Pancreatic Cancer: Recommendation Statement - U.S. Preventive Services ...
Dec 15, 2019 - The USPSTF recommends against screening for pancreatic cancer in asymptomatic adults.
American Family Physician : U.S. Preventive Services Task Force
https://www.aafp.org/afp/2019/1215/od1.html
Adding Ultrasonography to Mammography Increases False-Positive Findings Without an ...
Jan 1, 2020 - Adding ultrasonography to screening mammography in women younger than 50 years at low, intermediate, or high breast cancer risk is not associated with an increase in breast cancer detection. It is associated with increased unnecessary biopsy recommendations and results in more frequent ...
American Family Physician : POEMs
https://www.aafp.org/afp/2020/0101/p53a.html
Prolaris Test for Prostate Cancer Risk Assessment - Diagnostic Tests: What Physicians ...
Sep 1, 2019 - The Prolaris test improves the accuracy of prognosis for patients with prostate cancer, especially those with low- or intermediate-grade disease who may be deciding between interventional and noninterventional treatment approaches.
American Family Physician : Diagnostic Tests: What Physicians Need to Know
https://www.aafp.org/afp/2019/0901/p311.html
Screening for Pancreatic Cancer - Putting Prevention into Practice - American Family ...
Dec 15, 2019 - A 71-year-old woman comes to your office for a regularly scheduled visit. She has type 2 diabetes mellitus and a 50-pack-year smoking history, and had non-ulcer dyspepsia two years ago. Her body mass index is 32 kg per m2, and her blood pressure is normal.
American Family Physician : Putting Prevention into Practice
https://www.aafp.org/afp/2019/1215/p771.html
Aspirin for Colon Cancer Risk Prevention - FPIN's Clinical Inquiries - American Family ...
Nov 1, 2019 - Daily low-dose aspirin can be offered to patients older than 50 years for colon cancer prevention.
American Family Physician : FPIN's Clinical Inquiries
https://www.aafp.org/afp/2019/1101/od2.html
Primary Care of Adult Survivors of Childhood Cancer - American Family Physician
May 15, 2010 - There are approximately 300,000 survivors of childhood cancer in the United States, and most of them receive their medical care from primary care physicians. Adult survivors of childhood cancer are at considerable risk of long-term morbidity and mortality beyond the recurrence of their ...
American Family Physician : Article
https://www.aafp.org/afp/2010/0515/p1250.html
Screening for Cervical Cancer - Putting Prevention into Practice - American Family ...
Feb 15, 2019 - P.J., a 48-year-old woman, presents to your office for a well-woman examination. She has been married for eight years, has no history of sexually transmitted diseases, and has nothing remarkable in her medical history.
American Family Physician : Putting Prevention into Practice
https://www.aafp.org/afp/2019/0215/p253.html
Multiple Myeloma: Recognition and Management - American Family Physician
Apr 1, 1999 - Multiple myeloma is the malignant proliferation of plasma cells involving more than 10 percent of the bone marrow. The multiple myeloma cell produces monoclonal immunoglobulins that may be identified on serum or urine protein electrophoresis. Bone pain related to multiple lytic lesions ...
American Family Physician : Article
https://www.aafp.org/afp/1999/0401/p1885.html
Lung Cancer Screening: Pros and Cons - Lown Right Care: Reducing Overuse and Underuse -...
Jun 15, 2019 - A collaboration between AFP and the Lown Institute promotes a vision of delivering heath care that is based on the evidence, balanced in its approach, and focused on the patient.
American Family Physician : Lown Right Care: Reducing Overuse and Underuse
https://www.aafp.org/afp/2019/0615/p740.html
Lung Cancer Screening Recommendations from the ACCP - Practice Guidelines - American ...
Dec 1, 2018 - The American College of Chest Physicians (ACCP) recently published recommendations for lung cancer screening based on key questions developed using the PICO (population, intervention, comparator, and outcome) format.
American Family Physician : Practice Guidelines
https://www.aafp.org/afp/2018/1201/p688.html
mSEPT9 (Epi proColon) Blood Test for Colorectal Cancer Screening - Diagnostic Tests: ...
Jul 1, 2019 - Epi proColon is a blood test used for the detection of the methylated septin 9 (mSEPT9) gene. It is approved by the U.S. Food and Drug Administration for colorectal cancer screening in people at average risk who have declined first-line screening tests.
American Family Physician : Diagnostic Tests: What Physicians Need to Know
https://www.aafp.org/afp/2019/0701/p10.html
Omega-3 Fatty Acids Do Not Prevent Cancer or Cardiovascular Disease Events - POEMs - ...
Sep 15, 2019 - This is the second large, well-designed study (the first one included patients with diabetes mellitus; this one included patients without diabetes) that found no benefit from a 1-g daily dosage of marine n-3 fatty acid supplementation for the primary prevention of cardiovascular disease...
American Family Physician : POEMs
https://www.aafp.org/afp/2019/0915/p374a.html
Vitamin D Is Not Effective as Primary Prevention of Cardiovascular Disease or Cancer - ...
Sep 15, 2019 - Vitamin D supplementation does not prevent cardiovascular events or cancer in mostly nondiabetic adults (men 50 years and older, women 55 years and older).
American Family Physician : POEMs
https://www.aafp.org/afp/2019/0915/p374.html
Cancer Screening: ACS Releases Annual Summary of Recommendations - Practice Guidelines ...
Jun 1, 2019 - The American Cancer Society (ACS) provides a summary of recommendations for cancer screening each year, including any updates and recent data, and advice for when recommendations cannot be made.
American Family Physician : Practice Guidelines
https://www.aafp.org/afp/2019/0601/p719.html
Flexible Sigmoidoscopy or Fecal Occult Blood Testing for Colorectal Cancer Screening in...
Aug 1, 2019 - This meta-analysis provides high-quality evidence that flexible sigmoidoscopy and fecal occult blood testing both reduce the risk of death from colorectal cancer. The study did not provide a clear answer regarding a superior screening modality, so the decision to choose one test over ...
American Family Physician : Medicine by the Numbers
https://www.aafp.org/afp/2019/0801/od1.html
Primary Brain Tumors in Adults - American Family Physician
May 15, 2008 - Primary malignant brain tumors account for 2 percent of all cancers in U.S. adults. The most common malignant brain tumor is glioblastoma multiforme, and patients with this type of tumor have a poor prognosis. Previous exposure to high-dose ionizing radiation is the only proven ...
American Family Physician : Article
https://www.aafp.org/afp/2008/0515/p1423.html
Anticoagulation for the Long-term Treatment of VTE in Patients with Cancer - Cochrane ...
Jun 1, 2019 - Low-molecular-weight heparin (LMWH), vitamin K antagonists, and direct oral anticoagulants, when used to prevent recurrent VTE, have a similar impact on all-cause mortality.
American Family Physician : Cochrane for Clinicians
https://www.aafp.org/afp/2019/0601/p676.html
Aspirin, Eicosapentaenoic Acid, and Placebo Equally Effective in Preventing Colorectal ...
Jun 1, 2019 - After 12 months, neither aspirin nor EPA, alone or in combination, are any better than placebo at preventing colorectal adenomas in patients with high-risk neoplasia.
American Family Physician : POEMs
https://www.aafp.org/afp/2019/0601/p717.html
HPV Vaccine for Prevention of High-Grade Precancerous Cervical Lesions - Medicine by ...
Apr 1, 2019 - Data suggest the benefits of HPV vaccination for reducing precancerous lesions outweigh the potential harms. Find out more.
American Family Physician : Medicine by the Numbers
https://www.aafp.org/afp/2019/0401/od1.html
Colorectal Cancer Screening: ACS Updates Guideline for Adults with Average Risk - ...
Jan 15, 2019 - To support early identification and treatment, the American Cancer Society (ACS) has updated its 2008 guidance on counseling and referring patients at average risk of colorectal cancer (CRC) based on new evidence regarding screening options and the ever-changing risk of CRC.
American Family Physician : Practice Guidelines
https://www.aafp.org/afp/2019/0115/p129.html
FIT Has Similar Yield as Colonoscopy for Colorectal Cancer and Advanced Adenoma Over 10...
May 15, 2019 - Over a 10-year period, the rates of detection of colorectal cancer (CRC) and advanced adenomas using FIT are similar to those seen in studies of screening colonoscopy. This does not prove that FIT reduces morbidity and mortality due to CRC as effectively as colonoscopy.
American Family Physician : POEMs
https://www.aafp.org/afp/2019/0515/od5.html
Counseling Patients About Prostate Cancer Screening - Editorials - American Family ...
Oct 15, 2018 - The AAFP finds that the net benefit of population screening for prostate cancer is small at best, and it does not recommend routinely discussing PSA-based screening if the patient does not request it.
American Family Physician : Editorials
https://www.aafp.org/afp/2018/1015/p478.html
Recent Advances in Radiation Therapy - American Family Physician
Dec 1, 2008 - Recent advances have improved the effectiveness, decreased the complications, and expanded the implications of radiation therapy. These advances include three-dimensional conformal radiation therapy, intensity-modulated radiation therapy, stereotactic radiotherapy, brachytherapy, and ...
American Family Physician : Article
https://www.aafp.org/afp/2008/1201/p1254.html
Prophylactic Vaccination Against Human Papillomavirus to Prevent Cervical Cancer and ...
Jan 1, 2019 - HPV vaccination in women 15 to 26 years of age prevents the development of cervical intraepithelial neoplasia (CIN) 2 and CIN 3 in women regardless of previous HPV exposure (number needed to treat [NNT] = 39). No serious adverse effects are associated with administration of the HPV ...
American Family Physician : Cochrane for Clinicians
https://www.aafp.org/afp/2019/0101/p15.html
Stumbling onto Cancer: Avoiding Overdiagnosis of Renal Cell Carcinoma - Editorials - ...
Feb 1, 2019 - We all need to test wisely and weigh the risks and benefits of diagnostic imaging. Imaging—and testing in general—has real downsides, such as stumbling onto things you wish you had not.
American Family Physician : Editorials
https://www.aafp.org/afp/2019/0201/p145.html
Screening for Prostate Cancer - Putting Prevention into Practice - American Family ...
Oct 15, 2018 - A.E., a 57-year-old black man, comes to your office for an annual visit. He has a history of diabetes mellitus, has never smoked, and has no family history of prostate cancer. He is current with preventive services, including screening for colorectal cancer and counseling for a healthy ...
American Family Physician : Putting Prevention into Practice
https://www.aafp.org/afp/2018/1015/p537.html
Breast Cancer Screening with MRI: More False-Positives, More Biopsies - POEMs - ...
Nov 15, 2018 - Screening with MRI is not for everyone. Women who undergo breast cancer screening with MRI are much more likely to be referred for biopsy— that will ultimately be negative—than if they have screening mammography alone.
American Family Physician : POEMs
https://www.aafp.org/afp/2018/1115/od5.html
Screening for Prostate Cancer: Recommendation Statement - U.S. Preventive Services Task...
Oct 15, 2018 - Advertisement << Previous article Next article >> Oct 15, 2018 Issue U.S. Preventive Services Task Force Screening for Prostate Cancer: Recommendation Statement Am Fam Physician. 2018 Oct 15;98(8):online. Related Putting Prevention into Practice: Screening for Prostate Cancer...
American Family Physician : U.S. Preventive Services Task Force
https://www.aafp.org/afp/2018/1015/od1.html
Radon: A Leading Environmental Cause of Lung Cancer - Editorials - American Family ...
Sep 1, 2018 - Protracted exposure to radon is the leading environmental cause of cancer deaths in the United States. Family physicians play a key role in informing patients about the health risks.
American Family Physician : Editorials
https://www.aafp.org/afp/2018/0901/p280.html
HPV Testing Better Than Cytology for Women Vaccinated Against HPV - POEMs - American ...
Sep 15, 2018 - In women who had received the HPV vaccine, screening for HPV every five years, with cytology and colposcopy follow-up as needed, resulted in higher rates of identification of high-grade pre-cancerous disease than standard liquid-based cytology every 2.5 years with HPV follow-up ...
American Family Physician : POEMs
https://www.aafp.org/afp/2018/0915/p384.html
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