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Cancer - American Family Physician

Mar 1, 2021 - This collection features AFP content on cancer and related issues, including various types (breast, cervical, childhood, colorectal, lung, oral, ovarian, prostate, skin, testicular, and other types of cancer). This collection features AFP content on cancer and related issues, including ...

American Family Physician : AFP By Topic

https://www.aafp.org/afp/topicModules/viewTopicModule.htm?topicModuleId=31

Targeted Cancer Therapies - American Family Physician

Feb 1, 2021 - Targeted cancer therapies involve chemotherapeutic agents that attack, directly or indirectly, a specific genetic biomarker found in a given cancer. Targeted oncology includes monoclonal antibodies, small molecule inhibitors, antibody-drug conjugates, and immunotherapy. For example, the...

American Family Physician : Article

https://www.aafp.org/afp/2021/0201/p155.html

Screening for Cervical Intraepithelial Neoplasia with Patient-Collected HPV Samples - ...

Feb 1, 2021 - How useful are patient-collected human papillomavirus vaginal swabs as a screening test for cervical intraepithelial neoplasia?

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2021/0201/p181.html

Twenty-Year Follow-Up of Women's Health Initiative Trials: Lower Breast Cancer ...

Jan 15, 2021 - The cumulative 20-year follow-up report from the Women's Health Initiative hormone therapy trials found significantly lower breast cancer incidence and mortality among postmenopausal women who previously took conjugated equine estrogen (CEE; Premarin) alone (with a prior hysterectomy) ...

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0115/od1.html

Breast Cancer Screening: Common Questions and Answers - American Family Physician

Jan 1, 2021 - Breast cancer is the most common nonskin cancer in women and accounts for 30% of all new cancers in the United States. The highest incidence of breast cancer is in women 70 to 74 years of age. Numerous risk factors are associated with the development of breast cancer. A risk assessment ...

American Family Physician : Article

https://www.aafp.org/afp/2021/0101/p33.html

CT Colonography for Colorectal Cancer Screening - Diagnostic Tests: What Physicians ...

Jan 1, 2021 - Computed tomography colonography performs well for colorectal cancer screening. Long-term studies are needed to demonstrate its impact on patient morbidity and mortality, as well as to determine the risks, benefits, and costs.

American Family Physician : Diagnostic Tests: What Physicians Need to Know

https://www.aafp.org/afp/2021/0101/p55.html

Immunogenicity of Childhood Vaccines after Pediatric Cancer - FPIN's Clinical Inquiries...

Dec 1, 2020 - Children treated for cancer do not retain full immunity from previous vaccinations; therefore, it is likely beneficial for children who survive cancer to be revaccinated six to 12 months after immunosuppressive therapy.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2020/1201/od1.html

Basal Cell and Cutaneous Squamous Cell Carcinomas: Diagnosis and Treatment - American ...

Sep 15, 2020 - Keratinocyte carcinoma, traditionally referred to as nonmelanoma skin cancer, includes basal cell and cutaneous squamous cell carcinoma and is the most common skin cancer malignancy found in humans. The U.S. Preventive Services Task Force recommends counseling about minimizing exposure ...

American Family Physician : Article

https://www.aafp.org/afp/2020/0915/p339.html

Keratinocyte Carcinomas: Should We Screen for Them? - Editorials - American Family ...

Sep 15, 2020 - Keratinocyte carcinoma, which includes basal cell and cutaneous squamous cell carcinomas, is common, and the incidence is increasing.

American Family Physician : Editorials

https://www.aafp.org/afp/2020/0915/p330.html

Colorectal Cancer Screening: ACP Guidance Statements - Practice Guidelines - American ...

Aug 15, 2020 - The American College of Physicians developed a consensus statement for colorectal cancer screening of average-risk adults based on their review of six independent guidelines and supporting evidence.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2020/0815/p250.html

Colorectal Cancer Screening: BMJ Rapid Recommendation - Practice Guidelines - American ...

Aug 15, 2020 - Colorectal cancer (CRC) screening recommendations vary because the underlying evidence is low quality, with few screening methods evaluated by randomized trials. The BMJ/MAGIC Group performed a systematic review based on 15-year CRC risk models to compare screening options.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2020/0815/p253.html

VTE in Patients with Cancer: Guidelines from the American Society of Clinical Oncology ...

Aug 1, 2020 - The American Society of Clinical Oncology has updated recommendations for the prevention and treatment of venous thromboembolism (VTE) in patients with cancer.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2020/0801/p188.html

Mailing gFOBT or FIT Directly to Patients Increases Uptake of Colorectal Cancer ...

Jul 15, 2020 - Mailed outreach significantly increases rates of colorectal cancer screening, with four tests needing to be mailed to screen one person.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0715/p117.html

Cervical Colposcopy: Indications and Risk Assessment - American Family Physician

Jul 1, 2020 - The practice of colposcopy, a diagnostic procedure to evaluate for vaginal, vulvar, and cervical dysplasia, has evolved to incorporate patient risk factors for high-grade cervical intraepithelial neoplasia (CIN) and cancer. Changes in cervical cancer screening and guidelines, human ...

American Family Physician : Article

https://www.aafp.org/afp/2020/0701/p39.html

PAULA’s Test for Lung Cancer Screening - Diagnostic Tests: What Physicians Need to Know...

Jul 1, 2020 - Because of insufficient evidence of benefit, no recommendations can be made regarding PAULA's test. Prospective cohort studies of a screening population and randomized controlled trials comparing cancer mortality outcomes using PAULA's test vs. low-dose CT and no screening are needed ...

American Family Physician : Diagnostic Tests: What Physicians Need to Know

https://www.aafp.org/afp/2020/0701/p53.html

Supplemental MRI Screening in Women with Very Dense Breasts Reduces Interval Cancer ...

Jun 1, 2020 - Supplemental MRI screening for women with very dense breasts compared with mammography alone every two years significantly reduces the likelihood of an interval cancer, from 5 per 1,000 to 2.5 per 1,000 in the intention-to-treat population and to 0.8 per 1,000 in the per-protocol ...

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0601/p695a.html

Megestrol for Palliative Care in Patients with Cancer - FPIN's Clinical Inquiries - ...

May 1, 2020 - Megestrol may be considered as a component of palliative care nutritional support in patients with cancer.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2020/0501/od1.html

Results of Fecal Immunochemical Tests for Colorectal Cancer Screening Not Affected by ...

Apr 1, 2020 - The use of aspirin, NSAIDs, and oral anticoagulants has no clinically important effects on the positive predictive value of FIT in a screening population.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0401/p435.html

Medication Use to Reduce Risk of Breast Cancer - Putting Prevention into Practice - ...

Mar 15, 2020 - E.F., a 40-year-old woman, comes to your office for a routine gynecologic visit. She is not taking any medications and is generally healthy. She is sexually active, and her last menstrual period started 10 days ago.

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2020/0315/p373.html

Medication Use to Reduce Risk of Breast Cancer: Recommendation Statement - U.S. ...

Mar 15, 2020 - The USPSTF recommends that clinicians offer to prescribe risk-reducing medications, such as tamoxifen, raloxifene, or aromatase inhibitors, to women who are at increased risk for breast cancer and at low risk for adverse medication effects.

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2020/0315/od1.html

Integrating Breast Cancer Risk Management into Primary Care - Editorials - American ...

Mar 15, 2020 - It is important that primary care physicians have the ability and resources to identify women eligible for genetic counseling and testing for breast cancer.

American Family Physician : Editorials

https://www.aafp.org/afp/2020/0315/p330.html

Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer: ...

Feb 15, 2020 - The USPSTF recommends that primary care clinicians assess women with a personal or family history of breast, ovarian, tubal, or peritoneal cancer or who have an ancestry associated with breast cancer susceptibility 1 and 2 (BRCA1/2) gene mutations with an appropriate brief familial risk...

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2020/0215/p233.html

Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer - ...

Feb 15, 2020 - A 31-year-old woman presents to your office for a well-woman examination. She is sexually active in a monogamous relationship and has never been pregnant. She tells you that her mother was diagnosed with tubal cancer at age 40 and that her sister, who is 42 years of age, was recently ...

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2020/0215/p239.html

Breast Cancer Screening: ACP Releases Guidance Statements - Practice Guidelines - ...

Feb 1, 2020 - The American College of Physicians reviewed guidelines from other organizations and developed four statements to provide advice to clinicians about breast cancer screening for women who are at average risk.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2020/0201/p184.html

Lymphoma: Diagnosis and Treatment - American Family Physician

Jan 1, 2020 - Lymphoma is a group of malignant neoplasms of lymphocytes with more than 90 subtypes. It is traditionally classified broadly as non-Hodgkin or Hodgkin lymphoma. Approximately 82,000 new U.S. patients are diagnosed with lymphoma annually. Any tobacco use and obesity are major modifiable ...

American Family Physician : Article

https://www.aafp.org/afp/2020/0101/p34.html

Adding Ultrasonography to Mammography Increases False-Positive Findings Without an ...

Jan 1, 2020 - Adding ultrasonography to screening mammography in women younger than 50 years at low, intermediate, or high breast cancer risk is not associated with an increase in breast cancer detection. It is associated with increased unnecessary biopsy recommendations and results in more frequent ...

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0101/p53a.html

Screening for Pancreatic Cancer: Recommendation Statement - U.S. Preventive Services ...

Dec 15, 2019 - The USPSTF recommends against screening for pancreatic cancer in asymptomatic adults.

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2019/1215/od1.html

Screening for Pancreatic Cancer - Putting Prevention into Practice - American Family ...

Dec 15, 2019 - A 71-year-old woman comes to your office for a regularly scheduled visit. She has type 2 diabetes mellitus and a 50-pack-year smoking history, and had non-ulcer dyspepsia two years ago. Her body mass index is 32 kg per m2, and her blood pressure is normal.

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2019/1215/p771.html

Aspirin for Colon Cancer Risk Prevention - FPIN's Clinical Inquiries - American Family ...

Nov 1, 2019 - Daily low-dose aspirin can be offered to patients older than 50 years for colon cancer prevention.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2019/1101/od2.html

Omega-3 Fatty Acids Do Not Prevent Cancer or Cardiovascular Disease Events - POEMs - ...

Sep 15, 2019 - This is the second large, well-designed study (the first one included patients with diabetes mellitus; this one included patients without diabetes) that found no benefit from a 1-g daily dosage of marine n-3 fatty acid supplementation for the primary prevention of cardiovascular disease...

American Family Physician : POEMs

https://www.aafp.org/afp/2019/0915/p374a.html

Vitamin D Is Not Effective as Primary Prevention of Cardiovascular Disease or Cancer - ...

Sep 15, 2019 - Vitamin D supplementation does not prevent cardiovascular events or cancer in mostly nondiabetic adults (men 50 years and older, women 55 years and older).

American Family Physician : POEMs

https://www.aafp.org/afp/2019/0915/p374.html

Prolaris Test for Prostate Cancer Risk Assessment - Diagnostic Tests: What Physicians ...

Sep 1, 2019 - The Prolaris test improves the accuracy of prognosis for patients with prostate cancer, especially those with low- or intermediate-grade disease who may be deciding between interventional and noninterventional treatment approaches.

American Family Physician : Diagnostic Tests: What Physicians Need to Know

https://www.aafp.org/afp/2019/0901/p311.html

Flexible Sigmoidoscopy or Fecal Occult Blood Testing for Colorectal Cancer Screening in...

Aug 1, 2019 - This meta-analysis provides high-quality evidence that ﬂexible sigmoidoscopy and fecal occult blood testing both reduce the risk of death from colorectal cancer. The study did not provide a clear answer regarding a superior screening modality, so the decision to choose one test over ...

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2019/0801/od1.html

mSEPT9 (Epi proColon) Blood Test for Colorectal Cancer Screening - Diagnostic Tests: ...

Jul 1, 2019 - Epi proColon is a blood test used for the detection of the methylated septin 9 (mSEPT9) gene. It is approved by the U.S. Food and Drug Administration for colorectal cancer screening in people at average risk who have declined first-line screening tests.

American Family Physician : Diagnostic Tests: What Physicians Need to Know

https://www.aafp.org/afp/2019/0701/p10.html

Lung Cancer Screening: Pros and Cons - Lown Right Care: Reducing Overuse and Underuse -...

Jun 15, 2019 - A collaboration between AFP and the Lown Institute promotes a vision of delivering heath care that is based on the evidence, balanced in its approach, and focused on the patient.

American Family Physician : Lown Right Care: Reducing Overuse and Underuse

https://www.aafp.org/afp/2019/0615/p740.html

Cancer Screening: ACS Releases Annual Summary of Recommendations - Practice Guidelines ...

Jun 1, 2019 - The American Cancer Society (ACS) provides a summary of recommendations for cancer screening each year, including any updates and recent data, and advice for when recommendations cannot be made.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2019/0601/p719.html

Anticoagulation for the Long-term Treatment of VTE in Patients with Cancer - Cochrane ...

Jun 1, 2019 - Low-molecular-weight heparin (LMWH), vitamin K antagonists, and direct oral anticoagulants, when used to prevent recurrent VTE, have a similar impact on all-cause mortality.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0601/p676.html

Aspirin, Eicosapentaenoic Acid, and Placebo Equally Effective in Preventing Colorectal ...

Jun 1, 2019 - After 12 months, neither aspirin nor EPA, alone or in combination, are any better than placebo at preventing colorectal adenomas in patients with high-risk neoplasia.

American Family Physician : POEMs

https://www.aafp.org/afp/2019/0601/p717.html

FIT Has Similar Yield as Colonoscopy for Colorectal Cancer and Advanced Adenoma Over 10...

May 15, 2019 - Over a 10-year period, the rates of detection of colorectal cancer (CRC) and advanced adenomas using FIT are similar to those seen in studies of screening colonoscopy. This does not prove that FIT reduces morbidity and mortality due to CRC as effectively as colonoscopy.

American Family Physician : POEMs

https://www.aafp.org/afp/2019/0515/od5.html

HPV Vaccine for Prevention of High-Grade Precancerous Cervical Lesions - Medicine by ...

Apr 1, 2019 - Data suggest the benefits of HPV vaccination for reducing precancerous lesions outweigh the potential harms. Find out more.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2019/0401/od1.html

Primary Care of Breast Cancer Survivors - American Family Physician

Mar 15, 2019 - With declining mortality rates, the number of breast cancer survivors is increasing. Ongoing care after breast cancer treatment is often provided by primary care physicians. This care includes surveillance for cancer recurrence with a history and physical examination every three to six ...

American Family Physician : Article

https://www.aafp.org/afp/2019/0315/p370.html

Aspirin Plus a High-Dose PPI Prevents Death and Progression in Patients with Barrett ...

Mar 15, 2019 - In this study, patients with Barrett esophagus were less likely to die or develop esophageal cancer or high-grade dysplasia if they took high-dose esomeprazole (Nexium) alone or in combination with aspirin.

American Family Physician : POEMs

https://www.aafp.org/afp/2019/0315/od5.html