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Low-Dose Edoxaban Effective for Stroke Prevention in Older Patients with Atrial ... Restricted content. Login required.

Mar 1, 2021 - A lower dose of edoxaban is effective in decreasing stroke and systemic embolism in older patients with atrial fibrillation compared with placebo.

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0301/p312a.html

Aspirin after Acute Ischemic Stroke - Medicine by the Numbers - American Family Physician Restricted content. Login required.

Sep 1, 2020 - Learn more about the effect of aspirin therapy given within 48 hours of acute ischemic stroke in reducing the risk of death, dependence, or recurrent stroke, and the chance of complete recovery.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2020/0901/od2.html

Effectiveness of PPAR Gamma Agonists in Preventing Recurrent Stroke and Other Vascular ... Restricted content. Login required.

Sep 1, 2020 - PPAR gamma agonists are probably effective in preventing recurrent stroke in people with previous stroke or TIA.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2020/0901/p271.html

Daily Colchicine Post-MI Reduces Strokes and Recurrent Hospitalizations for Angina - ... Restricted content. Login required.

Aug 15, 2020 - Daily colchicine after MI reduces cardiovascular events, specifically strokes and hospitalizations for angina. It is inexpensive and well-tolerated and should be considered for patients with recent MIs who are already using guideline-directed therapy.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0815/p248.html

Small Reduction in Cardiovascular Outcome After Ischemic Stroke with Lower LDL Target, ... Restricted content. Login required.

Aug 15, 2020 - A lower LDL target slightly reduced the likelihood of a broad composite outcome (number needed to treat [NNT] = 43 over 3.5 years), largely by reducing nonfatal strokes (NNT = 77; statistical significance not reported).

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0815/p247.html

Dual Antiplatelet Therapy for High-Risk TIA and Minor Stroke: BMJ Rapid Recommendation ...

Sep 15, 2019 - Based on a recent randomized controlled trial followed by a systematic review, the BMJ and MAGIC group concluded that dual antiplatelet therapy use for a limited period after mild stroke is beneficial.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2019/0915/p378.html

Pioglitazone After Stroke or TIA Reduces Stroke and MI, but Also Has Significant Harms ...

Aug 15, 2016 - In patients with a recent stroke or TIA and evidence of insulin resistance, pioglitazone reduces the likelihood of myocardial infarction (MI) or stroke (number needed to treat [NNT] = 36 over five years) but increases the risk of significant weight gain (number needed to treat to harm ...

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0815/p319.html

Real-World Study Finds Lower Mortality and Stroke Risk with Dabigatran, but More GI ...

Sep 15, 2015 - In this well-designed observational study, older patients given an initial prescription of dabigatran had lower all-cause mortality and fewer ischemic and hemorrhagic strokes, but a higher risk of gastrointestinal (GI) bleeding, than a matched group of patients given warfarin.

American Family Physician : POEMs

https://www.aafp.org/afp/2015/0915/p529.html

CEA vs. Stenting: Mixed Results, Mostly Bad - POEMs - American Family Physician

Jul 1, 2015 - These two randomized trials, one with short-term outcomes and the other with five-year outcomes, demonstrate that carotid artery stenting results in more frequent strokes (clinical and radiographically detected) than carotid endarterectomy (CEA). However, the rate of fatal and disabling...

American Family Physician : POEMs

https://www.aafp.org/afp/2015/0701/p52.html

Increased GI Bleeding After Switch from Warfarin to Dabigatran - POEMs - American ...

May 1, 2015 - The risk of bleeding increases (though remains small) when patients with atrial fibrillation are switched from warfarin to dabigatran to prevent stroke or transient ischemic attack. This study, conducted almost exclusively in male veterans, found an increase in gastrointestinal (GI) ...

American Family Physician : POEMs

https://www.aafp.org/afp/2015/0501/p648.html

Rivaroxaban vs. Warfarin for Stroke Prevention in Patients with Nonvalvular Atrial ...

Mar 15, 2012 - How does rivaroxaban compare with warfarin for stroke prevention in patients with nonvalvular atrial fibrillation? This study concluded that rivaroxaban is noninferior to warfarin. However, noninferiority trials do not meet the same rigorous design and statistical format of traditional ...

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2012/0315/p577.html

Aspirin in Patients with Actue Ischemic Stroke - FPIN's Clinical Inquiries - American ...

Feb 1, 2009 - Aspirin in a daily dose of 160 to 300 mg initiated within 48 hours of symptom onset results in a net decrease in morbidity and mortality caused by acute ischemic stroke, based on a systematic review), regardless of the availability of computed tomography (CT).

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2009/0201/p226.html

Oral Anticoagulants vs. Antiplatelet Therapy - Cochrane for Clinicians - American ...

May 1, 2008 - Compared with antiplatelet therapy, oral anticoagulation significantly reduces stroke at an average follow-up of one to three years, but does not reduce mortality. Intracranial or extracranial hemorrhage is more common with anticoagulation and must be weighed against its therapeutic ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2008/0501/p1250.html

Practice Guidelines - May 15, 2006 - American Family Physician

May 15, 2006 - The Centers for Disease Control and Prevention (CDC) is investigating an outbreak of mumps that began in Iowa in December 2005. Other cases that were thought to be linked to the Iowa outbreak were being investigated in Illinois, Kansas, Minnesota, Missouri, Nebraska, and Wisconsin.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2006/0515/p1847.html

Practice Guidelines - May 15, 2006 - American Family Physician

May 15, 2006 - A subcommittee of the American Academy of Neurology (AAN) reviewed articles on carotid endarterectomy to assess the effectiveness of the procedure in preventing stroke in patients with internal carotid artery stenosis.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2006/0515/p1847a.html

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