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COVID-19 - American Family Physician

Oct 15, 2021 - Advertisement AFP BY TOPIC COVID-19 Editors' Choice of Best Available Content COVID-19 is an infectious disease caused by an enveloped single-stranded RNA novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), that was declared a pandemic by the World...

American Family Physician : AFP By Topic

https://www.aafp.org/afp/topicModules/viewTopicModule.htm?topicModuleId=117

Alcohol Withdrawal Syndrome: Outpatient Management - American Family Physician Restricted content. Login required.

Aug 1, 2021 - Approximately one-half of patients with alcohol use disorder who abruptly stop or reduce their alcohol use will develop signs or symptoms of alcohol withdrawal syndrome. The syndrome is due to overactivity of the central and autonomic nervous systems, leading to tremors, insomnia, ...

American Family Physician : Article

https://www.aafp.org/afp/2021/0900/p253.html

Melatonin to Treat Insomnia in Older Adults - FPIN's Clinical Inquiries - American ... Restricted content. Login required.

Aug 1, 2021 - Melatonin preparations reduce sleep-onset latency, increase total sleep time, and slightly improve sleep efficiency. Prolonged-release melatonin reduces sleep-onset latency in older adults and has rates of adverse effects similar to those of placebo.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2021/0900/p297.html

Pelvic Floor Muscle Training to Prevent and Treat Urinary and Fecal Incontinence in ... Restricted content. Login required.

Aug 1, 2021 - Structured PFMT beginning early in pregnancy prevents the onset of urge incontinence later in pregnancy and in the postpartum period compared with no intervention. There is no evidence that PFMT improves urinary incontinence later in pregnancy or in the postpartum period in pregnant ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2021/0900/p234.html

Comparison of Treatment Regimens for Helicobacter pylori Infection - Medicine by the ... Restricted content. Login required.

Aug 1, 2021 - A network meta-analysis found that vonoprazan-based triple therapy and reverse hybrid therapy demonstrated the highest overall cure rates and SUCRA values; however, among Western countries, levofloxacin-based triple therapy had the highest cure rate and SUCRA value. Standard triple ...

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2021/0900/od1.html

Remdesivir (Veklury) for the Treatment of COVID-19 in Hospitalized Patients - STEPS - ... Restricted content. Login required.

Aug 1, 2021 - Although remdesivir has been shown to be safe and well tolerated, there is a lack of consistency in clinical trial results and guideline recommendations.

American Family Physician : STEPS

https://www.aafp.org/afp/2021/0900/p311.html

Neonatal Abstinence Syndrome: A Call for Mother-Infant Dyad Treatment Approach - ...

Aug 1, 2021 - Neonatal abstinence syndrome (NAS) is a constellation of symptoms observed in newborns exposed to opioids during pregnancy. The incidence of NAS has steadily increased during the past decade as more infants have been born to mothers with opioid use disorder (OUD). Pregnancy and the ...

American Family Physician : Editorials

https://www.aafp.org/afp/2021/0900/p222.html

Epidural Corticosteroid Injections Provide Minimal, If Any, Benefit in Low Back Pain ... Restricted content. Login required.

Aug 1, 2021 - Epidural corticosteroid injections provide a small and probably clinically insignificant reduction in leg and back pain in the immediate term (less than two weeks), and a small to moderate reduction in disability in the short and intermediate terms.

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0900/od2.html

Neonatal Resuscitation: Updated Guidelines from the American Heart Association - ... Restricted content. Login required.

Aug 1, 2021 - The American Heart Association released minor updates to neonatal resuscitation recommendations with only minor changes to the previous algorithm.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2021/1000/p425.html

Take-and-Hold Prescriptions for Children with Respiratory Tract Infections Decrease ... Restricted content. Login required.

Aug 1, 2021 - A strategy of providing education about the natural history of respiratory symptoms in children combined with giving a take-and-hold prescription (to be filled only if symptoms persisted) resulted in one in four of those children eventually receiving an antibiotic.

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0900/od5.html

Schizophrenia: Use of Antipsychotic Drugs for Maintenance Therapy - Cochrane for ... Restricted content. Login required.

Aug 1, 2021 - Compared with placebo, using antipsychotic drugs for maintenance therapy in patients with schizophrenia is associated with relapse prevention at seven to 12 months.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2021/1000/p355.html

Interventions to Improve Use of CPAP Machines in Adults with Obstructive Sleep Apnea - ... Restricted content. Login required.

Aug 1, 2021 - Behavioral interventions increase CPAP use compared with usual care. These interventions also increase CPAP adherence, measured by participants using their machine four or more hours per night, from 371 to 501 per 1,000 patients.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2021/1000/p356.html

Does Light Therapy Decrease Depression in Older Adults? - FPIN's Clinical Inquiries - ... Restricted content. Login required.

Aug 1, 2021 - Light therapy appears to be mildly effective in treating depression in older adults, but ideal wavelength, intensity, and length of treatment are unknown.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2021/1000/p417.html

High-Dose Amoxicillin/Clavulanate No Better than Standard Dose for Acute Sinusitis in ... Restricted content. Login required.

Aug 1, 2021 - This study found no significant difference between the standard-dose and high-dose regimens of amoxicillin/clavulanate for treating acute sinusitis in adults. It is important to note that both doses are minimally superior to placebo.

American Family Physician : POEMs

https://www.aafp.org/afp/2021/1000/p423.html

For Patients with Type 2 Diabetes Mellitus Who Are Taking a GLP-1 Receptor Agonist, an ... Restricted content. Login required.

Aug 1, 2021 - This propensity score–matched analysis (not funded by industry) concluded that an SGLT2 inhibitor is preferred over a sulfonylurea for patients with type 2 diabetes who are already taking a GLP-1 receptor agonist, with favorable effects on the likelihood of hospitalization for ...

American Family Physician : POEMs

https://www.aafp.org/afp/2021/1000/p424.html

Ultrasound Guidance for the Placement of Peripheral Intravenous Catheters - Medicine by... Restricted content. Login required.

Aug 1, 2021 - Learn more about ultrasound guidance for the placement of peripheral intravenous catheters.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2021/1000/od2.html

Breast Cancer Treatment - American Family Physician Restricted content. Login required.

Jul 1, 2021 - Breast cancer is the leading cause of death from cancer in women worldwide, and the second most common cause of death from cancer in women in the United States. Risk assessment tools can identify the risk of breast cancer, and patients at high risk may be candidates for risk-reducing ...

American Family Physician : Article

https://www.aafp.org/afp/2021/0800/p171.html

Pharmacologic Therapy for Acute Pain - American Family Physician Restricted content. Login required.

Jul 1, 2021 - Pharmacologic management of acute pain should be tailored for each patient, including a review of treatment expectations and a plan for the time course of prescriptions. Acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs) are first-line treatment options for most patients ...

American Family Physician : Article

https://www.aafp.org/afp/2021/0700/p63.html

Inhaled Budesonide Reduces the Risk of Emergency Department Evaluation or ... Restricted content. Login required.

Jul 1, 2021 - Inhaled budesonide, 800 mcg twice daily, significantly reduces the likelihood that patients with early COVID-19 will require emergency department evaluation or hospitalization (number needed to treat = 7 to 8). This is a widely available, relatively inexpensive drug with the potential ...

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0800/p207.html

GeneSight Psychotropic Genetic Testing for Psychiatric Medication Selection - ... Restricted content. Login required.

Jul 1, 2021 - The GeneSight test may assist in drug selection and dosing for individuals having difficulty finding an effective option or who have had intolerable adverse effects after trials of several drugs. However, because only a small population of patients are expected to have genetic ...

American Family Physician : Diagnostic Tests: What Physicians Need to Know

https://www.aafp.org/afp/2021/0700/p89.html

Treatment of Chronic Obstructive Pulmonary Disease: Guidelines from the VA/DoD - ... Restricted content. Login required.

Jul 1, 2021 - The U.S. Department of Veterans Affairs and U.S. Department of Defense published guidelines for the primary care management of COPD.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2021/0700/p98.html

Clascoterone (Winlevi) for the Treatment of Acne - STEPS - American Family Physician Restricted content. Login required.

Jul 1, 2021 - More comparative data are needed to justify the use of clascoterone over less expensive, currently available therapies for moderate to severe acne. However, systemic absorption of clascoterone is low, and it may serve as a safe alternative for patients 12 years and older who saw ...

American Family Physician : STEPS

https://www.aafp.org/afp/2021/0700/p93.html

SGLT2 Inhibitors or GLP-1 Receptor Agonists Reduce Cardiovascular Outcomes in Patients ... Restricted content. Login required.

Jul 1, 2021 - SGLT2 inhibitors, the diabetes medications ending in -flozin, and GLP-1 receptor agonists, the -tide medications, decrease cardiovascular and renal outcomes to a greater extent than placebo or other treatments. They should be considered in addition to metformin and other ...

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0800/p206.html

Hydrochlorothiazide vs. Chlorthalidone for the Treatment of Hypertension - FPIN's Help ... Restricted content. Login required.

Jul 1, 2021 - Chlorthalidone reduces systolic blood pressure by 10 mm Hg more than hydrochlorothiazide at equal dosages in patients using monotherapy. Low-dose chlorthalidone and controlled-release hydrochlorothiazide reduce 24-hour ambulatory systolic blood pressure and diastolic blood pressure, ...

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2021/0800/p203.html

Can Pioglitazone Prevent or Delay Type 2 Diabetes in Patients with Prediabetes? - ... Restricted content. Login required.

Jul 1, 2021 - Pioglitazone prevents or delays the incidence of type 2 diabetes in individuals with prediabetes when compared with placebo (absolute risk reduction [ARR] = 11.3%; 95% CI, 0.9% to 15.6%; number needed to treat [NNT] = 9) or no intervention (ARR = 13.3%; 95% CI, 11.6% to 14.9%; NNT = 7)....

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2021/0800/p139.html

Treatment of Chronic Obstructive Pulmonary Disease: Guidelines from the American ... Restricted content. Login required.

Jul 1, 2021 - The American Thoracic Society published guidelines for pharmacologic management of COPD and long-term oxygen therapy for COPD and interstitial lung disease based on systematic reviews.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2021/0700/p102.html

Treatment of Chronic Obstructive Pulmonary Disease Exacerbations: Guidelines from the ... Restricted content. Login required.

Jul 1, 2021 - Run by May 2022; run with ATS and VA/DoD PGs; conflicts:

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2021/0700/p100.html

Pharmacologic Management of Agitation in Patients with Dementia - FPIN's Clinical ... Restricted content. Login required.

Jul 1, 2021 - Selective serotonin reuptake inhibitors and risperidone are moderately effective at decreasing agitation in all types of dementia. Olanzapine and risperidone reduce dementia-related agitation much longer than placebo. Dextromethorphan/quinidine may be effective at reducing agitation in ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2021/0700/p91.html

Once-Weekly Semaglutide Is an Effective Adjunct for Weight Loss in Adults without ... Restricted content. Login required.

Jul 1, 2021 - Once-weekly subcutaneous semaglutide used as an adjunct to intensive behavioral therapy significantly improves the likelihood that adults without diabetes who are overweight or obese will lose at least 5% of their baseline body weight compared with placebo.

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0700/p96.html

Levonorgestrel-Releasing Intrauterine System for Reducing Heavy Menstrual Bleeding - ... Restricted content. Login required.

Jul 1, 2021 - The levonorgestrel-releasing intrauterine system is more effective than other medical therapies at reducing menstrual bleeding volume, with similar rates of adverse effects. The effectiveness of the levonorgestrel-releasing intrauterine system compared with endometrial ablation and ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2021/0800/p138.html

Acromioclavicular Joint Dislocation: Surgical vs. Conservative Interventions - Cochrane... Restricted content. Login required.

Jul 1, 2021 - Surgical treatment for AC joint dislocation of the shoulder does not appear to be superior to conservative management in adults. Surgical therapy increases the risk of hardware complications, infection, and continued discomfort.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2021/0700/p28.html

Pharmacogenetic Gene-Drug Associations: FDA Perspective on What Physicians Need to Know...

Jul 1, 2021 - To share its perspective on the state of the science, the FDA has published a table of pharmacogenetic associations related to genetic variants that can affect drug concentrations, therapeutic responses, or adverse events.

American Family Physician : Editorials

https://www.aafp.org/afp/2021/0700/p16.html

Single-Dose Opioid Analgesics Offer No Benefit over Nonopioid Analgesia for ... Restricted content. Login required.

Jul 1, 2021 - A single dose of opioid analgesics provides similar acute pain relief compared with a single dose of a combination of acetaminophen and ibuprofen in patients with acute musculoskeletal pain in the emergency department.

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0700/p95a.html

Cryoablation Preferred as Initial Therapy for Paroxysmal Atrial Fibrillation - POEMs - ... Restricted content. Login required.

Jul 1, 2021 - Initial cryoablation for patients with paroxysmal AF is superior to initial antiarrhythmic drug therapy. Another study in the same issue of New England Journal of Medicine compared cryoablation with medical therapy and had similar findings.

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0700/p97.html

Low-Carb Diets May Produce Short-Term Diabetes Remission - POEMs - American Family ... Restricted content. Login required.

Jul 1, 2021 - Patients with type 2 diabetes can try cutting out bread and pasta, leaving the skin on chicken, or eating nuts and avocados to lower their blood glucose levels. Six months of a low-carbohydrate diet (less than 26% of calories from carbohydrates) was more likely than other diets or usual...

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0700/p95.html

Levonorgestrel-Releasing Intrauterine System for Regression of Endometrial Hyperplasia ... Restricted content. Login required.

Jul 1, 2021 - A Cochrane review compared the levonorgestrel-releasing intrauterine system with progesterone for the treatment of endometrial hyperplasia.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2021/0700/p26.html

Tighter Blood Pressure Control Does Not Increase the Likelihood of Orthostatic ... Restricted content. Login required.

Jul 1, 2021 - Orthostatic hypotension, a drop of 20 mm Hg systolic or 10 mm Hg diastolic after moving from sitting to standing, was not associated with more intensive treatment of blood pressure and may be less likely to occur with intensive treatment.

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0800/p208.html

Obstetric Lacerations: Prevention and Repair - American Family Physician Restricted content. Login required.

Jun 15, 2021 - Obstetric lacerations are a common complication of vaginal delivery. Lacerations can lead to chronic pain and urinary and fecal incontinence. Perineal lacerations are defined by the depth of musculature involved, with fourth-degree lacerations disrupting the anal sphincter and the ...

American Family Physician : Article

https://www.aafp.org/afp/2021/0615/p745.html

Hypertension: New Guidelines from the International Society of Hypertension - Practice ... Restricted content. Login required.

Jun 15, 2021 - The International Society of Hypertension has published summary guidelines based on major international guidelines published between 2017 and 2020 on the control of hypertension. These summary guidelines include essential recommendations and suggestions for optimal care.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2021/0615/p763.html

Interventions for Tobacco Smoking Cessation in Adults, Including Pregnant Persons: ...

Jun 15, 2021 - The USPSTF recommends that clinicians ask all adults about tobacco use, advise them to stop using tobacco, and provide behavioral interventions and U.S. Food and Drug Administration-approved pharmacotherapy for cessation to nonpregnant adults who use tobacco.

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2021/0615/od1.html

Interventions for Tobacco Smoking Cessation in Adults, Including Pregnant Persons - ... Restricted content. Login required.

Jun 15, 2021 - A 27-year-old patient, R.C., with a history of generalized anxiety disorder presents for a wellness examination. R.C. previously smoked a pack of cigarettes per day but has cut down to half a pack per day and started using electronic cigarettes (e-cigarettes) and is interested in ...

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2021/0615/p753.html

Poor Physician-Patient Communication and Medical Error - Lown Right Care: Reducing ... Restricted content. Login required.

Jun 15, 2021 - A collaboration between AFP and the Lown Institute promotes a vision of delivering health care that is based on the evidence, balanced in its approach, and focused on the patient.

American Family Physician : Lown Right Care: Reducing Overuse and Underuse

https://www.aafp.org/afp/2021/0615/p757.html

Lipid Lowering Is Beneficial for Secondary Prevention but Not Primary Prevention in ... Restricted content. Login required.

Jun 1, 2021 - Does lipid lowering reduce major vascular events in patients 75 years and older?

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0601/p695a.html

Preoperative A1C Threshold in Patients with Diabetes - FPIN's Clinical Inquiries - ... Restricted content. Login required.

Jun 1, 2021 - In patients with diabetes mellitus who are preparing for total joint replacement, what is the preoperative A1C goal to reduce postoperative periprosthetic joint infections?

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2021/0601/p693.html

Psychological Therapies for Women Who Experience Intimate Partner Violence - Cochrane ... Restricted content. Login required.

Jun 1, 2021 - Are psychological therapies safe and effective for women who experience intimate partner violence?

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2021/0601/p661.html

Pessaries for Managing Pelvic Organ Prolapse in Women - Cochrane for Clinicians - ... Restricted content. Login required.

Jun 1, 2021 - Pessaries combined with pelvic floor muscle training (PFMT) probably improve pelvic organ prolapse symptoms in women and prolapse-specific quality of life compared with PFMT alone.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2021/0601/p660.html

Exercise Is the Only Intervention to Provide Long-Term Improvement in Patients with ... Restricted content. Login required.

Jun 1, 2021 - What interventions are effective in managing patients with chronic low back pain?

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0601/p696.html

Oxytocin as First-line Uterotonic Therapy for Postpartum Hemorrhage - Medicine by the ... Restricted content. Login required.

Jun 1, 2021 - Oxytocin decreases the chances of a blood transfusion and has fewer adverse effects compared with misoprostol.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2021/0601/p656.html

Post-ICU Care in the Outpatient Setting - American Family Physician Restricted content. Login required.

May 15, 2021 - More than 5 million patients in the United States are admitted to intensive care units (ICUs) annually, and an increasing percentage of patients treated in the ICU survive to hospital discharge. Because these patients require follow-up in the outpatient setting, family physicians should...

American Family Physician : Article

https://www.aafp.org/afp/2021/0515/p590.html

Key Potentially Inappropriate Drugs in Pediatrics: The KIDs List - Practice Guidelines ... Restricted content. Login required.

May 15, 2021 - The Pediatric Pharmacy Association produced a list of key potentially inappropriate drugs in pediatrics, or the KIDs List, to guide physicians who treat children.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2021/0515/p633.html

SGLT2 Inhibitors Improve All-Cause and Cardiovascular Mortality in Patients Regardless ... Restricted content. Login required.

May 15, 2021 - What effect do sodium-glucose cotransporter-2 (SGLT2) inhibitors have on mortality and cardiovascular and renal outcomes in patients with and without diabetes mellitus, heart failure, or kidney disease?

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0515/p630a.html

Colchicine Reduces MI and Revascularization in Patients with Established Coronary ... Restricted content. Login required.

May 15, 2021 - Colchicine, 0.5 mg daily, significantly reduces the risk of myocardial infarction and ischemia-driven revascularization.

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0515/p631a.html

In-flight Medical Emergencies - American Family Physician Restricted content. Login required.

May 1, 2021 - In 2018, approximately 2.8 million passengers flew in and out of U.S. airports per day. Twenty-four to 130 in-flight medical emergencies are estimated to occur per 1 million passengers; however, there is no internationally agreed-upon recording or classification system. Up to 70% of ...

American Family Physician : Article

https://www.aafp.org/afp/2021/0501/p547.html

Eosinophilic Esophagitis: Management Guidelines from the AGA and JTF - Practice ... Restricted content. Login required.

May 1, 2021 - The American Gastroenterological Association (AGA) and the Joint Task Force on Allergy-Immunology Practice Parameters (JTF) published guidelines for treatment of eosinophilic esophagitis.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2021/0501/p573.html

Nonopioid Pharmacologic Treatments for Chronic Pain - Implementing AHRQ Effective ... Restricted content. Login required.

May 1, 2021 - What are the effects of nonopioid drugs on pain, function, and quality of life in patients with specific types of chronic pain, and what are the adverse events related to these drugs?

American Family Physician : Implementing AHRQ Effective Health Care Reviews

https://www.aafp.org/afp/2021/0501/p561.html

Ibuprofen vs. Acetaminophen for Fever or Pain in Children Younger Than Two Years - ... Restricted content. Login required.

May 1, 2021 - A meta-analysis found that ibuprofen is more effective than acetaminophen in reducing fever and pain in children younger than two years, although further study is needed to evaluate combination therapy, dosing, and use in children younger than six months.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2021/0501/od1.html

Exercise for Dysmenorrhea - Cochrane for Clinicians - American Family Physician Restricted content. Login required.

May 1, 2021 - Low-intensity exercise, such as stretching or core strengthening, and high-intensity exercise, such as Zumba or aerobic training, improve menstrual pain intensity compared with no exercise.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2021/0501/p525.html

Ketogenic Diets for Drug-Resistant Epilepsy - Cochrane for Clinicians - American Family... Restricted content. Login required.

May 1, 2021 - In children with drug-resistant epilepsy, a ketogenic diet decreases the risk of seizures by 50% after three to four months.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2021/0501/p524.html

Mifepristone and Misoprostol for Early Pregnancy Loss and Medication Abortion - ... Restricted content. Login required.

Apr 15, 2021 - Medication regimens using mifepristone and misoprostol are safe and effective for outpatient treatment of early pregnancy loss for up to 84 days’ gestation and for medication abortion up to 77 days’ gestation. Gestational age is determined using ultrasonography or menstrual history. ...

American Family Physician : Article

https://www.aafp.org/afp/2021/0415/p473.html

Key Recommendations on Managing Dyslipidemia for Cardiovascular Risk Reduction: ...

Apr 15, 2021 - In June 2020, the third iteration of the U.S. Department of Veterans Affairs and Department of Defense guidelines on managing dyslipidemia was published. These recommendations create a simple, pragmatic, evidence-based approach that can be valuable to family physicians.

American Family Physician : Editorials

https://www.aafp.org/afp/2021/0415/p455.html

Dyslipidemia Management for Cardiovascular Disease Prevention: Guidelines from the ... Restricted content. Login required.

Apr 15, 2021 - The U.S. Department of Veterans Affairs and Department of Defense have updated recommendations for evaluation and management of dyslipidemia to prevent cardiovascular disease.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2021/0415/p507.html

Elagolix, Estradiol, and Norethindrone Kit (Oriahnn) for the Management of Heavy ... Restricted content. Login required.

Apr 15, 2021 - Oriahnn can decrease menstrual blood loss in premenopausal patients with uterine fibroids. Although it has been studied for only six months of use and may result in significant bone loss, it is labeled for up to two years of continuous therapy.

American Family Physician : STEPS

https://www.aafp.org/afp/2021/0415/p505.html

Nerve Blocks for Pancreatic Cancer Pain - FPIN's Help Desk Answers - American Family ... Restricted content. Login required.

Apr 15, 2021 - Celiac plexus blocks can be used for pain associated with pancreatic cancer. They slightly reduce pain while decreasing opioid consumption, with fewer adverse effects compared with standard analgesic therapy.

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2021/0415/p502.html

HIV Infection in Adults: Initial Management - American Family Physician Restricted content. Login required.

Apr 1, 2021 - The HIV epidemic is an important public health priority. Transmissions continue to occur despite effective therapies that make HIV preventable and treatable. Approximately one-half of people with HIV are not receiving suppressive antiretroviral therapy (ART). Starting ART early, ...

American Family Physician : Article

https://www.aafp.org/afp/2021/0401/p407.html

Obstructive Sleep Apnea and Chronic Insomnia Disorder: Updated Guidelines from the ... Restricted content. Login required.

Apr 1, 2021 - The U.S. Department of Veterans Affairs and Department of Defense (VA/DoD) approved a clinical practice guideline for the management of obstructive sleep apnea and chronic insomnia disorder.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2021/0401/p442.html

Treatment of Distal DVT - Medicine by the Numbers - American Family Physician Restricted content. Login required.

Apr 1, 2021 - A Cochrane review demonstrated that anticoagulation was effective and superior to observation for deep venous thrombosis; however, given the quality of the evidence, the benefits are unclear.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2021/0401/p432.html

Active vs. Expectant Management in the Third Stage of Labor - Cochrane for Clinicians -... Restricted content. Login required.

Apr 1, 2021 - Very low-quality evidence suggests that active management of the third stage of labor reduces the risk of severe primary postpartum hemorrhage greater than 1,000 mL.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2021/0401/p404.html

Kinesiology Taping for Knee Osteoarthritis Pain - FPIN's Clinical Inquiries - American ... Restricted content. Login required.

Apr 1, 2021 - How effective is kinesiology taping (elastic tape applied to the knee to create patellar tension) for osteoarthritis pain of the knee?

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2021/0401/p434.html

Epidural Corticosteroid Injections for Lumbosacral Radicular Pain - Cochrane for ... Restricted content. Login required.

Apr 1, 2021 - Epidural corticosteroid injections for the treatment of lumbosacral radicular pain may offer modest short-term (two weeks to three months) benefit compared with placebo injection for radicular leg pain.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2021/0401/p405.html

iCanQuit Smartphone App Is Effective in Helping with Smoking Cessation - POEMs - ... Restricted content. Login required.

Apr 1, 2021 - Use of the iCanQuit smartphone app by smokers, who were recruited through Facebook and other Internet tools, produced higher cessation rates at 12 months (28.2%) than the QuitGuide app (21.1%).

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0401/p441.html

Three Strategies Are Effective in Managing Patients with Medication Overuse Headaches -... Restricted content. Login required.

Apr 1, 2021 - Achieving cure from medication overuse headaches after six months was likely regardless of strategy: detoxification (discontinuation of analgesic) plus pharmacologic prophylaxis, pharmacologic prophylaxis without withdrawal, or detoxification with pharmacologic preventive therapy ...

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0401/p439a.html

In High-Risk Older Patients with Atrial Fibrillation, Rhythm Control Reduces ... Restricted content. Login required.

Apr 1, 2021 - In high-risk older patients with recent-onset atrial fibrillation, a strategy of rhythm control results in fewer cardiovascular deaths and fewer strokes.

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0401/p440.html

Musculoskeletal Surgery for Nontraumatic Pain: Not a Great Analgesic - POEMs - American... Restricted content. Login required.

Apr 1, 2021 - Musculoskeletal surgery is invaluable for unintentional injury. But for conditions associated with chronic pain (e.g., knee, shoulder, wrist, neck, back pain), even patients with objective changes on imaging that need intervention will not have better long-term pain relief with surgery ...

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0401/p439.html

Topical Corticosteroids: Choice and Application - American Family Physician Restricted content. Login required.

Mar 15, 2021 - Topical corticosteroids are an essential tool for treating inflammatory skin conditions such as psoriasis and atopic dermatitis. Topical corticosteroids are classified by strength and the risk of adverse effects such as atrophy, striae, rosacea, telangiectasias, purpura, and other ...

American Family Physician : Article

https://www.aafp.org/afp/2021/0315/p337.html

Medications for Smoking Cessation: Guidelines from the American Thoracic Society - ... Restricted content. Login required.

Mar 15, 2021 - The American Thoracic Society (ATS) published guidelines for medication initiation in tobacco-dependent adults based on a systematic review.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2021/0315/p380.html

The KIDs List: Medications That Are Potentially Inappropriate in Children - Editorials ...

Mar 15, 2021 - The Key Potentially Inappropriate Drugs in Pediatrics (KIDs) List is an open access, evidence-based reference aimed at improving medication safety in children.

American Family Physician : Editorials

https://www.aafp.org/afp/2021/0315/p330.html

Bempedoic Acid (Nexletol) for the Treatment of Hyperlipidemia and Familial ... Restricted content. Login required.

Mar 15, 2021 - Bempedoic acid is labeled as add-on therapy to diet and maximally tolerated statin for the treatment of familial hypercholesterolemia or atherosclerotic cardiovascular disease.

American Family Physician : STEPS

https://www.aafp.org/afp/2021/0315/p377.html

Initiating Hormonal Contraception - American Family Physician Restricted content. Login required.

Mar 1, 2021 - Most patients can safely begin using hormonal contraception at any point in their menstrual cycle. An evidence-based, flexible, patient-centered approach to initiating contraception promotes health and enhances patients’ reproductive autonomy. A recent Papanicolaou test is not necessary...

American Family Physician : Article

https://www.aafp.org/afp/2021/0301/p291.html

Difficult-to-Treat and Severe Asthma: Management Strategies - American Family Physician Restricted content. Login required.

Mar 1, 2021 - Asthma is a common chronic inflammatory disease in the United States. Up to 17% of asthma cases are classified as difficult to treat, and 3.7% of these are considered severe. Uncontrolled asthma is characterized by poor symptom control or frequent exacerbations. In difficult-to-treat ...

American Family Physician : Article

https://www.aafp.org/afp/2021/0301/p286.html

Antiplatelet Agents for Preventing Early Recurrence of Ischemic Stroke or TIA - ... Restricted content. Login required.

Mar 1, 2021 - After atherothrombotic ischemic stroke or transient ischemic attack, adding clopidogrel to aspirin reduced recurrent strokes but increased major hemorrhages.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2021/0301/od1.html

Enhancing Diabetes Self-Management Education and Support in Clinical Practice - ...

Mar 1, 2021 - Health systems and family physicians should mobilize to ensure that all people with type 2 diabetes have access to diabetes self-management education and support, including nutritional, physical, and emotional support.

American Family Physician : Editorials

https://www.aafp.org/afp/2021/0301/p265.html

Alcoholics Anonymous and Other 12-Step Facilitation Programs for Alcohol Use Disorder -... Restricted content. Login required.

Mar 1, 2021 - Manualized (standardized and replicable) Alcoholics Anonymous and similar 12-step facilitation programs produce higher rates of continuous abstinence than other established treatments.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2021/0301/p272.html

Serum Lactate Testing to Predict Mortality in Patients with Sepsis - Diagnostic Tests: ... Restricted content. Login required.

Mar 1, 2021 - Management of patients with sepsis is challenging and mortality is high. Early diagnosis and prompt initiation of therapy are essential. Higher lactate levels correlate with increased risk of mortality, particularly with lactate levels greater than 4.0 mmol per L and in the setting of ...

American Family Physician : Diagnostic Tests: What Physicians Need to Know

https://www.aafp.org/afp/2021/0301/p309.html

Low-Dose Edoxaban Effective for Stroke Prevention in Older Patients with Atrial ... Restricted content. Login required.

Mar 1, 2021 - A lower dose of edoxaban is effective in decreasing stroke and systemic embolism in older patients with atrial fibrillation compared with placebo.

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0301/p312a.html

Lemborexant (Dayvigo) for the Treatment of Insomnia - STEPS - American Family Physician Restricted content. Login required.

Feb 15, 2021 - Lemborexant (Davigo) is labeled for adults with insomnia to improve with sleep onset and maintenance.

American Family Physician : STEPS

https://www.aafp.org/afp/2021/0215/p241.html

Intravenous Magnesium Sulfate for Acute Asthma Exacerbation in Children and Adults - ... Restricted content. Login required.

Feb 15, 2021 - Patients who received intravenous magnesium sulfate for acute asthma exacerbation in the emergency department had decreased hospital admissions and no serious adverse effects.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2021/0215/p245.html

Sexual Assault of Women - American Family Physician Restricted content. Login required.

Feb 1, 2021 - Sexual violence is a major public health and human rights issue affecting more than 40% of women in the United States during their lifetimes. Although men and women experience sexual assault, women are at greatest risk. Populations uniquely impacted by sexual assault include ...

American Family Physician : Article

https://www.aafp.org/afp/2021/0201/p168.html

Targeted Cancer Therapies - American Family Physician Restricted content. Login required.

Feb 1, 2021 - Targeted cancer therapies involve chemotherapeutic agents that attack, directly or indirectly, a specific genetic biomarker found in a given cancer. Targeted oncology includes monoclonal antibodies, small molecule inhibitors, antibody-drug conjugates, and immunotherapy. For example, the...

American Family Physician : Article

https://www.aafp.org/afp/2021/0201/p155.html

Topical and Device-Based Treatment of Toenail Onychomycosis - Cochrane for Clinicians -... Restricted content. Login required.

Feb 1, 2021 - Topical antifungal drugs, including efinaconazole 10% solution (Jublia), tavaborole 5% solution (Kerydin), and ciclopirox 8% lacquer and hydrolacquer, are beneficial in treating mild to moderate toenail onychomycosis. Potential adverse effects are mild and include dermatitis and vesicles.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2021/0201/p145.html

Buffering Lidocaine 1%/ Epinephrine with Sodium Bicarbonate in a 3:1 Ratio Is as ... Restricted content. Login required.

Jan 15, 2021 - Lido/Epi buffered with NaHCO3 in a 3:1 ratio is significantly less painful during infiltration than unbuffered Lido/Epi and buffered Lido/Epi in a 9:1 ratio.

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0115/od4.html

Icosapent Ethyl (Vascepa) for Hyperlipidemia/Hypercholesterolemia to Reduce Risk of ... Restricted content. Login required.

Jan 15, 2021 - Icosapent ethyl is safe, well tolerated and effective in preventing ischemic events including stroke and heart attack.

American Family Physician : STEPS

https://www.aafp.org/afp/2021/0115/p117.html

Twenty-Year Follow-Up of Women's Health Initiative Trials: Lower Breast Cancer ... Restricted content. Login required.

Jan 15, 2021 - The cumulative 20-year follow-up report from the Women's Health Initiative hormone therapy trials found significantly lower breast cancer incidence and mortality among postmenopausal women who previously took conjugated equine estrogen (CEE; Premarin) alone (with a prior hysterectomy) ...

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0115/od1.html

Triple Inhaled Therapy Provides a Small Reduction in Moderate COPD Exacerbations, No ... Restricted content. Login required.

Jan 15, 2021 - Triple inhaled therapy, with budesonide (Pulmicort) in a dose of either 160 mcg or 320 mcg daily plus a long-acting muscarinic antagonist (LAMA) and a long-acting beta2 agonist (LABA), reduces moderate exacerbations (a need for an antibiotic or steroid for three or more days) more than ...

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0115/od2.html

Short-Term Low Back Pain Relief with Placebo - POEMs - American Family Physician Restricted content. Login required.

Jan 15, 2021 - Over three weeks, patients with long-term low back pain who knowingly took placebo twice a day reported less pain and disability than those continuing with treatment as usual.

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0115/od3.html

Testosterone Therapy for Age-Related Low Testosterone: Guidelines from the ACP - ... Restricted content. Login required.

Jan 1, 2021 - The American College of Physicians published guidelines for testosterone therapy in cis gender men with age-related low testosterone based on a systematic review.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2021/0101/p60.html

Medications for Treatment-Resistant Depression in Adults - Cochrane for Clinicians - ... Restricted content. Login required.

Jan 1, 2021 - In patients with treatment-resistant depression, augmenting therapy with atypical antipsychotics can be effective.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2021/0101/p16.html

Treatment of Distal DVT - Cochrane for Clinicians - American Family Physician Restricted content. Login required.

Jan 1, 2021 - Vitamin K antagonists reduce the recurrence of DVT and VTE (number needed to treat [NNT] = 17; 95% CI, 13 to 48) but not pulmonary embolism (PE) compared with no anticoagulation or placebo.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2021/0101/p18.html

Effectiveness of Alarm Therapy in the Treatment of Nocturnal Enuresis in Children - ... Restricted content. Login required.

Jan 1, 2021 - This review concluded that alarm therapy appears to be effective for treating nocturnal enuresis in children, but it is uncertain if it is more effective than other interventions.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2021/0101/od1.html

Electronic Cigarettes for Smoking Cessation - FPIN's Clinical Inquiries - American ... Restricted content. Login required.

Jan 1, 2021 - e-Cigarettes with nicotine can be used to encourage smoking cessation, but continued use after cessation may be a risk factor for relapse.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2021/0101/p53.html

Off-Label Use and Misuse of Hormone Supplements: AACE and ACE Position Statement - ... Restricted content. Login required.

Dec 15, 2020 - The American Association of Clinical Endocrinologists and the American College of Endocrinology developed a summary of known risks of using off-label hormone treatments.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2020/1215/p759.html

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