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Clascoterone (Winlevi) for the Treatment of Acne - STEPS - American Family Physician Restricted content. Login required.

Jul 1, 2021 - More comparative data are needed to justify the use of clascoterone over less expensive, currently available therapies for moderate to severe acne. However, systemic absorption of clascoterone is low, and it may serve as a safe alternative for patients 12 years and older who saw ...

American Family Physician : STEPS

https://www.aafp.org/afp/2021/0700/p93.html

Treatment of Chronic Obstructive Pulmonary Disease: Guidelines from the VA/DoD - ... Restricted content. Login required.

Jul 1, 2021 - The U.S. Department of Veterans Affairs and U.S. Department of Defense published guidelines for the primary care management of COPD.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2021/0700/p98.html

SGLT2 Inhibitors or GLP-1 Receptor Agonists Reduce Cardiovascular Outcomes in Patients ... Restricted content. Login required.

Jul 1, 2021 - SGLT2 inhibitors, the diabetes medications ending in -flozin, and GLP-1 receptor agonists, the -tide medications, decrease cardiovascular and renal outcomes to a greater extent than placebo or other treatments. They should be considered in addition to metformin and other ...

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0800/p206.html

Diagnosis and Initial Management of Acute Colonic Diverticulitis - Implementing AHRQ ... Restricted content. Login required.

Jul 1, 2021 - What are the benefits and harms of diagnostic testing, and what is the effectiveness of treatment options for acute colonic diverticulitis?

American Family Physician : Implementing AHRQ Effective Health Care Reviews

https://www.aafp.org/afp/2021/0800/p195.html

Hydrochlorothiazide vs. Chlorthalidone for the Treatment of Hypertension - FPIN's Help ... Restricted content. Login required.

Jul 1, 2021 - Chlorthalidone reduces systolic blood pressure by 10 mm Hg more than hydrochlorothiazide at equal dosages in patients using monotherapy. Low-dose chlorthalidone and controlled-release hydrochlorothiazide reduce 24-hour ambulatory systolic blood pressure and diastolic blood pressure, ...

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2021/0800/p203.html

Fallacies and Dangers of Practicing Race-Based Medicine - Editorials - American Family ...

Jul 1, 2021 - Race does not have a biologic definition, but rather a political and social one that is fluid and independent of science. Nevertheless, the medical community uses race as a scientific variable in several prominent clinical situations, including calculation of atherosclerotic ...

American Family Physician : Editorials

https://www.aafp.org/afp/2021/0800/p122.html

Treatment of Chronic Obstructive Pulmonary Disease: Guidelines from the American ... Restricted content. Login required.

Jul 1, 2021 - The American Thoracic Society published guidelines for pharmacologic management of COPD and long-term oxygen therapy for COPD and interstitial lung disease based on systematic reviews.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2021/0700/p102.html

Treatment of Chronic Obstructive Pulmonary Disease Exacerbations: Guidelines from the ... Restricted content. Login required.

Jul 1, 2021 - Run by May 2022; run with ATS and VA/DoD PGs; conflicts:

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2021/0700/p100.html

Rapid Point-of-Care Antigen and Molecular Tests for Diagnosis of SARS-CoV-2 Infection -... Restricted content. Login required.

Jul 1, 2021 - SARS-CoV-2 antigen tests have an average sensitivity of 68.9% and an average specificity of 99.6%. Accuracy depends on symptom status, time from symptom onset, and test brand.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2021/0700/p29.html

Can Pioglitazone Prevent or Delay Type 2 Diabetes in Patients with Prediabetes? - ... Restricted content. Login required.

Jul 1, 2021 - Pioglitazone prevents or delays the incidence of type 2 diabetes in individuals with prediabetes when compared with placebo (absolute risk reduction [ARR] = 11.3%; 95% CI, 0.9% to 15.6%; number needed to treat [NNT] = 9) or no intervention (ARR = 13.3%; 95% CI, 11.6% to 14.9%; NNT = 7)....

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2021/0800/p139.html

Pharmacologic Management of Agitation in Patients with Dementia - FPIN's Clinical ... Restricted content. Login required.

Jul 1, 2021 - Selective serotonin reuptake inhibitors and risperidone are moderately effective at decreasing agitation in all types of dementia. Olanzapine and risperidone reduce dementia-related agitation much longer than placebo. Dextromethorphan/quinidine may be effective at reducing agitation in ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2021/0700/p91.html

Once-Weekly Semaglutide Is an Effective Adjunct for Weight Loss in Adults without ... Restricted content. Login required.

Jul 1, 2021 - Once-weekly subcutaneous semaglutide used as an adjunct to intensive behavioral therapy significantly improves the likelihood that adults without diabetes who are overweight or obese will lose at least 5% of their baseline body weight compared with placebo.

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0700/p96.html

Skin Inflammation After Immunization - Photo Quiz - American Family Physician Restricted content. Login required.

Jul 1, 2021 - A patient develops erythema and warmth on the arm two weeks after receiving the first dose of the mRNA-1273 vaccine against the SARS-CoV-2 virus.

American Family Physician : Photo Quiz

https://www.aafp.org/afp/2021/0700/p81.html

Screening for Lung Cancer - Putting Prevention into Practice - American Family Physician Restricted content. Login required.

Jul 1, 2021 - S.J., a 68-year-old Black man, comes to your office to establish care after recently moving to the area. S.J. has a history of allergic rhinitis, osteoarthritis, and gastroesophageal reflux disease. Additionally, he has a 39-pack-year history of smoking but quit six years ago.

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2021/0700/p79.html

Prioritizing Primary Care Can Save the U.S. Health Care System - Editorials - American ...

Jul 1, 2021 - Can prioritizing primary care save the U.S. health care system?

American Family Physician : Editorials

https://www.aafp.org/afp/2021/0700/p14.html

Red, Raised Papule on the Chest - Photo Quiz - American Family Physician Restricted content. Login required.

Jul 1, 2021 - A patient presented with a red, slightly raised papule on the anterior chest wall.

American Family Physician : Photo Quiz

https://www.aafp.org/afp/2021/0800/p199.html

Acromioclavicular Joint Dislocation: Surgical vs. Conservative Interventions - Cochrane... Restricted content. Login required.

Jul 1, 2021 - Surgical treatment for AC joint dislocation of the shoulder does not appear to be superior to conservative management in adults. Surgical therapy increases the risk of hardware complications, infection, and continued discomfort.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2021/0700/p28.html

Addressing Loneliness and Social Isolation in Older Adults - Curbside Consultation - ... Restricted content. Login required.

Jul 1, 2021 - Social isolation and loneliness are increasingly recognized as complex clinical and public health problems, particularly in older adults, leading to adverse mental and physical health outcomes. The COVID-19 pandemic has led to physical distancing policies, which have exacerbated ...

American Family Physician : Curbside Consultation

https://www.aafp.org/afp/2021/0700/p85.html

Levonorgestrel-Releasing Intrauterine System for Reducing Heavy Menstrual Bleeding - ... Restricted content. Login required.

Jul 1, 2021 - The levonorgestrel-releasing intrauterine system is more effective than other medical therapies at reducing menstrual bleeding volume, with similar rates of adverse effects. The effectiveness of the levonorgestrel-releasing intrauterine system compared with endometrial ablation and ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2021/0800/p138.html

Acute Sharp Flank Pain - Photo Quiz - American Family Physician Restricted content. Login required.

Jul 1, 2021 - A patient presented with stiffness and pain in his lower back and both thighs and an abnormal CT scan.

American Family Physician : Photo Quiz

https://www.aafp.org/afp/2021/0800/p201.html

Nontender Rash on the Soles of the Feet in a Febrile Adult - Photo Quiz - American ... Restricted content. Login required.

Jul 1, 2021 - A patient with multiple medical conditions presented with nonpurulent cellulitis and MRSA bacteremia.

American Family Physician : Photo Quiz

https://www.aafp.org/afp/2021/0700/p83.html

Prenatal Vitamins, Patellofemoral Pain Syndrome, Alcohol Misuse, Hernia, Anaphylaxis, ... Restricted content. Login required.

Jul 1, 2021 - Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.

American Family Physician : AFP Clinical Answers

https://www.aafp.org/afp/2021/0800/p137.html

More than One-Half of Adults Hospitalized for COVID-19 Still Report Significant ... Restricted content. Login required.

Jul 1, 2021 - This study found that more than one-half of the adults (51%) who had been hospitalized for COVID-19 reported a significant amount of persistent symptoms four months after discharge.

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0800/p206a.html

Physical Activity and the Prevention of Depression - FPIN's Clinical Inquiries - ... Restricted content. Login required.

Jul 1, 2021 - Physical activity appears to be associated with a lower risk of developing depression and depressive symptoms.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2021/0800/p204.html

Pharmacogenetic Gene-Drug Associations: FDA Perspective on What Physicians Need to Know...

Jul 1, 2021 - To share its perspective on the state of the science, the FDA has published a table of pharmacogenetic associations related to genetic variants that can affect drug concentrations, therapeutic responses, or adverse events.

American Family Physician : Editorials

https://www.aafp.org/afp/2021/0700/p16.html

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