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Breast Cancer Screening: Common Questions and Answers - American Family Physician Restricted content. Login required.

Jan 1, 2021 - Breast cancer is the most common nonskin cancer in women and accounts for 30% of all new cancers in the United States. The highest incidence of breast cancer is in women 70 to 74 years of age. Numerous risk factors are associated with the development of breast cancer. A risk assessment ...

American Family Physician : Article

https://www.aafp.org/afp/2021/0101/p33.html

Cervical Colposcopy: Indications and Risk Assessment - American Family Physician Restricted content. Login required.

Jul 1, 2020 - The practice of colposcopy, a diagnostic procedure to evaluate for vaginal, vulvar, and cervical dysplasia, has evolved to incorporate patient risk factors for high-grade cervical intraepithelial neoplasia (CIN) and cancer. Changes in cervical cancer screening and guidelines, human ...

American Family Physician : Article

https://www.aafp.org/afp/2020/0701/p39.html

Cervical Cancer Screening - American Family Physician

Apr 1, 2018 - Screening in women has decreased the incidence and mortality of cervical cancer. Precancerous cervical lesions (cervical intraepithelial neoplasias) and cervical carcinomas are strongly associated with sexually-transmitted high-risk human papillomavirus (HPV) infection, which causes ...

American Family Physician : Article

https://www.aafp.org/afp/2018/0401/p441.html

Diagnosis and Management of Adnexal Masses - American Family Physician

Apr 15, 2016 - Adnexal masses can have gynecologic or nongynecologic etiologies, ranging from normal luteal cysts to ovarian cancer to bowel abscesses. Women who report abdominal or pelvic pain, increased abdominal size or bloating, difficulty eating, or rapid satiety that occurs more than 12 times ...

American Family Physician : Article

https://www.aafp.org/afp/2016/0415/p676.html

Primary Care of Breast Cancer Survivors - American Family Physician

Mar 15, 2019 - With declining mortality rates, the number of breast cancer survivors is increasing. Ongoing care after breast cancer treatment is often provided by primary care physicians. This care includes surveillance for cancer recurrence with a history and physical examination every three to six ...

American Family Physician : Article

https://www.aafp.org/afp/2019/0315/p370.html

Diagnosis and Management of Endometrial Cancer - American Family Physician

Mar 15, 2016 - Endometrial cancer is the most common gynecologic malignancy. It is the fourth most common cancer in women in the United States after breast, lung, and colorectal cancers. Risk factors are related to excessive unopposed exposure of the endometrium to estrogen, including unopposed ...

American Family Physician : Article

https://www.aafp.org/afp/2016/0315/p468.html

Diagnosis and Management of Ovarian Cancer - American Family Physician

Jun 1, 2016 - Ovarian cancer is the most lethal gynecologic cancer. Less than one-half of patients survive for more than five years after diagnosis. Ovarian cancer affects women of all ages but is most commonly diagnosed after menopause. More than 75% of affected women are diagnosed at an advanced ...

American Family Physician : Article

https://www.aafp.org/afp/2016/0601/p937.html

Cervical Cancer: Evaluation and Management - American Family Physician

Apr 1, 2018 - Human papillomavirus infection is the precursor for the development of cervical cancer and is detectable in 99.7% of squamous cell carcinoma and adenocarcinoma cases. Early detection of precancerous lesions with Papanicolaou testing remains the primary mechanism for cancer prevention. ...

American Family Physician : Article

https://www.aafp.org/afp/2018/0401/p449.html

Gynecologic Procedures: Colposcopy, Treatments of Cervical Intraepithelial Neoplasia, ...

Jun 15, 2013 - Women who have abnormal Papanicolaou test results may undergo colposcopy to determine the biopsy site for histologic evaluation. Traditional grading systems do not accurately assess lesion severity because colposcopic impression alone is unreliable for diagnosis. The likelihood of ...

American Family Physician : Article

https://www.aafp.org/afp/2013/0615/p836.html

Update on ASCCP Consensus Guidelines for Abnormal Cervical Screening Tests and Cervical...

Jul 15, 2009 - New data have emerged since publication of the American Society for Colposcopy and Cervical Pathology's 2001 consensus guidelines for management of abnormal cervical cytology and histology. The 2006 guidelines include recommendations for special populations (i.e., adolescents and ...

American Family Physician : Article

https://www.aafp.org/afp/2009/0715/p147.html

Screening for Cervical Intraepithelial Neoplasia with Patient-Collected HPV Samples - ... Restricted content. Login required.

Feb 1, 2021 - How useful are patient-collected human papillomavirus vaginal swabs as a screening test for cervical intraepithelial neoplasia?

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2021/0201/p181.html

Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer: ...

Feb 15, 2020 - The USPSTF recommends that primary care clinicians assess women with a personal or family history of breast, ovarian, tubal, or peritoneal cancer or who have an ancestry associated with breast cancer susceptibility 1 and 2 (BRCA1/2) gene mutations with an appropriate brief familial risk...

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2020/0215/p233.html

Breast Cancer Screening: ACP Releases Guidance Statements - Practice Guidelines - ...

Feb 1, 2020 - The American College of Physicians reviewed guidelines from other organizations and developed four statements to provide advice to clinicians about breast cancer screening for women who are at average risk.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2020/0201/p184.html

Supplemental MRI Screening in Women with Very Dense Breasts Reduces Interval Cancer ... Restricted content. Login required.

Jun 1, 2020 - Supplemental MRI screening for women with very dense breasts compared with mammography alone every two years significantly reduces the likelihood of an interval cancer, from 5 per 1,000 to 2.5 per 1,000 in the intention-to-treat population and to 0.8 per 1,000 in the per-protocol ...

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0601/p695a.html

Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer - ...

Feb 15, 2020 - A 31-year-old woman presents to your office for a well-woman examination. She is sexually active in a monogamous relationship and has never been pregnant. She tells you that her mother was diagnosed with tubal cancer at age 40 and that her sister, who is 42 years of age, was recently ...

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2020/0215/p239.html

Ovarian Cancer: An Overview - American Family Physician

Sep 15, 2009 - Although ovarian cancer may occur at any age, it is more common in patients older than 50 years. Patients often present with nonspecific pelvic or abdominal symptoms. Initial diagnostic tests include transvaginal ultrasonography and serum cancer antigen 125 measurement; however, these ...

American Family Physician : Article

https://www.aafp.org/afp/2009/0915/p609.html

Medication Use to Reduce Risk of Breast Cancer: Recommendation Statement - U.S. ...

Mar 15, 2020 - The USPSTF recommends that clinicians offer to prescribe risk-reducing medications, such as tamoxifen, raloxifene, or aromatase inhibitors, to women who are at increased risk for breast cancer and at low risk for adverse medication effects.

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2020/0315/od1.html

Medication Use to Reduce Risk of Breast Cancer - Putting Prevention into Practice - ...

Mar 15, 2020 - E.F., a 40-year-old woman, comes to your office for a routine gynecologic visit. She is not taking any medications and is generally healthy. She is sexually active, and her last menstrual period started 10 days ago.

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2020/0315/p373.html

Integrating Breast Cancer Risk Management into Primary Care - Editorials - American ...

Mar 15, 2020 - It is important that primary care physicians have the ability and resources to identify women eligible for genetic counseling and testing for breast cancer.

American Family Physician : Editorials

https://www.aafp.org/afp/2020/0315/p330.html

Endometrial Cancer - American Family Physician

Nov 15, 2009 - Endometrial cancer is the leading cause of gynecologic cancer in the United States. Etiologically, endometrial carcinoma usually results from unopposed estrogen stimulation of the endometrium, although non-estrogen-related forms occur as well. The most common presentation of endometrial...

American Family Physician : Article

https://www.aafp.org/afp/2009/1115/p1075.html

Screening for Cervical Cancer: Recommendation Statement - U.S. Preventive Services Task...

Feb 15, 2019 - The USPSTF recommends screening for cervical cancer every 3 years with cervical cytology alone in women aged 21 to 29 years. For women aged 30 to 65 years, the USPSTF recommends screening every 3 years with cervical cytology alone, every 5 years with high-risk human papillomavirus ...

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2019/0215/od1.html

Adding Ultrasonography to Mammography Increases False-Positive Findings Without an ...

Jan 1, 2020 - Adding ultrasonography to screening mammography in women younger than 50 years at low, intermediate, or high breast cancer risk is not associated with an increase in breast cancer detection. It is associated with increased unnecessary biopsy recommendations and results in more frequent ...

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0101/p53a.html

Screening for Cervical Cancer - Putting Prevention into Practice - American Family ...

Feb 15, 2019 - P.J., a 48-year-old woman, presents to your office for a well-woman examination. She has been married for eight years, has no history of sexually transmitted diseases, and has nothing remarkable in her medical history.

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2019/0215/p253.html

HPV Vaccine for Prevention of High-Grade Precancerous Cervical Lesions - Medicine by ...

Apr 1, 2019 - Data suggest the benefits of HPV vaccination for reducing precancerous lesions outweigh the potential harms. Find out more.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2019/0401/od1.html

Prophylactic Vaccination Against Human Papillomavirus to Prevent Cervical Cancer and ...

Jan 1, 2019 - HPV vaccination in women 15 to 26 years of age prevents the development of cervical intraepithelial neoplasia (CIN) 2 and CIN 3 in women regardless of previous HPV exposure (number needed to treat [NNT] = 39). No serious adverse effects are associated with administration of the HPV ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0101/p15.html

Screening for Ovarian Cancer: Recommendation Statement - U.S. Preventive Services Task ...

Jun 15, 2018 - The USPSTF recommends against screening for ovarian cancer in asymptomatic women.

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2018/0615/od1.html

HPV Testing Better Than Cytology for Women Vaccinated Against HPV - POEMs - American ...

Sep 15, 2018 - In women who had received the HPV vaccine, screening for HPV every five years, with cytology and colposcopy follow-up as needed, resulted in higher rates of identification of high-grade pre-cancerous disease than standard liquid-based cytology every 2.5 years with HPV follow-up ...

American Family Physician : POEMs

https://www.aafp.org/afp/2018/0915/p384.html

Screening for Ovarian Cancer - Putting Prevention into Practice - American Family ...

Jun 15, 2018 - A 61-year-old woman presents to your office for a well-woman examination. She had a normal Papanicolaou (Pap) test last year and has no medical problems. She quit smoking 10 years ago, reports a family history significant only for cardiovascular disease, and is sexually active with her ...

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2018/0615/p813.html

Repeat Cytology Within Six Months Equals Colposcopy for Younger Women with ASCUS or ...

Apr 1, 2017 - Among women 22 to 27 years of age with an index cervical cytology showing abnormal squamous cells of undetermined significance (ASCUS) or low-grade squamous intraepithelial lesion (LSIL), the incidence of invasive cervical cancer did not differ between repeat cytology within six months ...

American Family Physician : POEMs

https://www.aafp.org/afp/2017/0401/p455.html

Screening for Breast Cancer - Putting Prevention into Practice - American Family Physician

Jul 15, 2016 - S.O. is a 47-year-old woman who presents to your office for a well-woman visit. She is healthy, takes no medications, and has no health concerns. She has never been diagnosed with breast cancer, nor have any of her first-degree relatives. Her digital mammography two years ago was ...

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2016/0715/p143.html

What Women and Their Physicians Need to Know About the UKCTOCS Study and Ovarian Cancer...

Jun 1, 2016 - An overview of the recent results from the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) and implications for clinical practice and public health.

American Family Physician : Editorials

https://www.aafp.org/afp/2016/0601/p903.html

Screening for Ovarian Cancer—More Hype Than Hope? - Editorials - American Family Physician

Jun 1, 2016 - In keeping with the principles of the Choosing Wisely campaign, physicians and patients would do well to avoid the pitfalls of overscreening and wait for results that promise more hope than hype.

American Family Physician : Editorials

https://www.aafp.org/afp/2016/0601/p906.html

ACP Releases Best Practice Advice on Screening for Cervical Cancer - Practice ...

Dec 15, 2015 - Based on the best available evidence, the American College of Physicians (ACP) has released best practice advice on cervical cancer screening in average-risk, asymptomatic women 21 years or older. This advice is targeted to all clinicians, and refers to screening for cervical ...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2015/1215/p1107.html

Management of Histologic Abnormalities of the Cervix - American Family Physician

Jan 1, 2006 - The American Society for Colposcopy and Cervical Pathology sponsored a consensus conference in 2001 to develop evidence-based guidelines for women with histologic abnormalities of the cervix. The options for management of cervical intraepithelial neoplasia 1, 2, and 3 are ranked ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0101/p105.html

CIN Treatment May Increase Miscarriages but Does Not Affect Fertility - POEMs - ...

Apr 1, 2015 - In this analysis of 15 observational studies (it would be difficult and unethical to do randomized research on this topic), excision using any method for CIN did not affect fertility, although second trimester miscarriages were more likely. A study published at the same time found the ...

American Family Physician : POEMs

https://www.aafp.org/afp/2015/0401/p490.html

Medications for Risk Reduction of Primary Breast Cancer in Women: Recommendation ...

Nov 1, 2014 - The U.S. Preventive Services Task Force (USPSTF) recommends that clinicians engage in shared, informed decision making with women who are at increased risk of breast cancer about medications to reduce their risk. For women who are at increased risk of breast cancer and at low risk of ...

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2014/1101/od1.html

Evaluation and Management of the AGUS Papanicolaou Smear - American Family Physician

Jun 1, 2001 - Atypical glandular cells on Papanicolaou smears are an unusual but important cytologic diagnosis. The Bethesda system classifies atypical glandular cells of undetermined significance (AGUS) as glandular cells that demonstrate nuclear atypia appearing to exceed reactive or reparative ...

American Family Physician : Article

https://www.aafp.org/afp/2001/0601/p2239.html

Anastrozole Decreases Rate of Breast Cancer in High-Risk Postmenopausal Women - POEMs -...

Aug 15, 2014 - Postmenopausal women at high risk of developing breast cancer who take anastrozole for five years have a lower rate of developing invasive breast cancer during that time frame.

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0815/od7.html

Management of Cervical Cytologic Abnormalities - American Family Physician

Nov 15, 2004 - The American Society for Colposcopy and Cervical Pathology developed guidelines in 2001 for the management of cervical cytologic abnormalities. The guidelines incorporate the Bethesda System 2001 terminology and data from randomized studies of atypical squamous cells, low-grade ...

American Family Physician : Article

https://www.aafp.org/afp/2004/1115/p1905.html

HPV Screening Every Five Years Equal to Pap Smear Every Three Years - POEMs - American ...

Jun 1, 2014 - A single HPV test provides the same degree of protection over five years as a Papanicolaou (Pap) smear does for three years. We may soon see a recommendation for HPV testing as a stand-alone screen, with cytology reserved for women who have an HPV-positive result. We may also be able to...

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0601/p907a.html

ACOG Releases Guidelines on Cervical Cancer Screening - Practice Guidelines - American ...

Dec 1, 2013 - The incidence of cervical cancer, as well as mortality rates from the disease, has decreased over the past 30 years because of widespread screening with cervical cytology. Screening technologies and risk-benefit considerations for different age groups continue to evolve. The American ...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2013/1201/p776.html

The 2001 Bethesda System Terminology - American Family Physician

Nov 15, 2003 - The 2001 Bethesda System for reporting cervical or vaginal cytologic diagnoses is an incremental change in the uniform terminology introduced in 1988 and revised in 1991. The 2001 Bethesda System includes specific statements about specimen adequacy, general categorization, and ...

American Family Physician : Article

https://www.aafp.org/afp/2003/1115/p1992.html

Screening for Ovarian Cancer: Reaffirmation Recommendation Statement - U.S. Preventive ...

May 15, 2013 - The U.S. Preventive Services Task Force (USPSTF) recommends against screening for ovarian cancer in women.

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2013/0515/od1.html

Screening for Ovarian Cancer - Putting Prevention into Practice - American Family ...

May 15, 2013 - Case study: A 55-year-old woman presents for a routine well-woman examination. She states that she is worried about ovarian cancer because one of her friends was recently diagnosed. She has no family history of breast, ovarian, or colon cancer.

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2013/0515/p709.html

Does Screening Mammography Lead to Overdiagnosis of Invasive Breast Cancer? - AFP ...

Mar 15, 2013 - Implementation of a universal mammographic screening program leads to an increase in the diagnosis of invasive breast cancer, because of improved detection of clinically significant cancer and overdiagnosis.

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2013/0315/p408.html

ACS/ASCCP/ASCP Guidelines for the Early Detection of Cervical Cancer - Editorials - ...

Sep 15, 2012 - The American Cancer Society (ACS), the American Society for Colposcopy and Cervical Pathology (ASCCP), and the American Society for Clinical Pathology (ASCP) recently published updated recommendations for the early detection of cervical cancer. The guidelines are based on a systematic ...

American Family Physician : Editorials

https://www.aafp.org/afp/2012/0915/p501.html

Screening for Cervical Cancer - Putting Prevention into Practice - American Family ...

Sep 15, 2012 - Case study: J.K., a 45-year-old woman, presents to your office for a routine well-woman examination. She has been married for 20 years, and there is nothing remarkable in her medical history, including no previous abnormal Papanicolaou (Pap) smears.

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2012/0915/p563.html

Screening for Cervical Cancer: Recommendation Statement - U.S. Preventive Services Task...

Sep 15, 2012 - The U.S. Preventive Services Task Force (USPSTF) recommends screening for cervical cancer in women 21 to 65 years of age with cytology (Papanicolaou [Pap] smear) every three years or, for women 30 to 65 years of age who want to lengthen the screening interval, screening with a ...

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2012/0915/p555.html

Cervical Cancer - American Family Physician

Mar 1, 2000 - Cervical cancer is the second most common type of cancer in women worldwide, after breast cancer. A preponderance of evidence supports a causal link between human papillomavirus infection and cervical neoplasia. The presence of high-risk human papillomavirus genital subtypes increases ...

American Family Physician : Article

https://www.aafp.org/afp/2000/0301/p1369.html

Vulvar Cancer - American Family Physician

Oct 1, 2002 - Vulvar cancer was reported in 3,200 women in 1998, resulting in 800 deaths. Recent evidence suggests that vulvar cancer comprises two separate diseases. The first type may develop from vulvar intraepithelial neoplasia caused by human papillomavirus infection and is increasing in ...

American Family Physician : Article

https://www.aafp.org/afp/2002/1001/p1269.html

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