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Unexplained Lymphadenopathy: Evaluation and Differential Diagnosis - American Family ...

Dec 1, 2016 - Lymphadenopathy is benign and self-limited in most patients. Etiologies include malignancy, infection, and autoimmune disorders, as well as medications and iatrogenic causes. The history and physical examination alone usually identify the cause of lymphadenopathy. When the cause is ...

American Family Physician : Article

https://www.aafp.org/afp/2016/1201/p896.html

Evaluation of Patients with Leukocytosis - American Family Physician

Dec 1, 2015 - An elevated white blood cell count has many potential etiologies, including malignant and nonmalignant causes. It is important to use age- and pregnancy-specific normal ranges for the white blood cell count. A repeat complete blood count with peripheral smear may provide helpful ...

American Family Physician : Article

https://www.aafp.org/afp/2015/1201/p1004.html

Persistent Night Sweats: Diagnostic Evaluation - American Family Physician Restricted content. Login required.

Oct 1, 2020 - Night sweats are a nonspecific symptom that patients commonly experience but rarely discuss with their physicians without prompting. Although many life-threatening causes such as malignancies or infections have been described, most patients who report persistent night sweats in the ...

American Family Physician : Article

https://www.aafp.org/afp/2020/1001/p427.html

Colorectal Cancer Screening and Surveillance in Individuals at Increased Risk - ...

Jan 15, 2018 - Individuals at increased risk of developing colorectal cancer include those with a personal or family history of advanced adenomas or colorectal cancer, a personal history of inflammatory bowel disease, or genetic polyposis syndromes. In general, these persons should undergo more ...

American Family Physician : Article

https://www.aafp.org/afp/2018/0115/p111.html

Cervical Colposcopy: Indications and Risk Assessment - American Family Physician Restricted content. Login required.

Jul 1, 2020 - The practice of colposcopy, a diagnostic procedure to evaluate for vaginal, vulvar, and cervical dysplasia, has evolved to incorporate patient risk factors for high-grade cervical intraepithelial neoplasia (CIN) and cancer. Changes in cervical cancer screening and guidelines, human ...

American Family Physician : Article

https://www.aafp.org/afp/2020/0701/p39.html

Cervical Cancer Screening - American Family Physician

Apr 1, 2018 - Screening in women has decreased the incidence and mortality of cervical cancer. Precancerous cervical lesions (cervical intraepithelial neoplasias) and cervical carcinomas are strongly associated with sexually-transmitted high-risk human papillomavirus (HPV) infection, which causes ...

American Family Physician : Article

https://www.aafp.org/afp/2018/0401/p441.html

Colorectal Cancer Screening and Surveillance - American Family Physician

Jan 15, 2015 - Colorectal cancer is the third most common cancer in men and women. The incidence and mortality rate of the disease have been declining over the past two decades because of early detection and treatment. Screening in persons at average risk should begin at 50 years of age; the U.S. ...

American Family Physician : Article

https://www.aafp.org/afp/2015/0115/p93.html

Colorectal Cancer Screening and Prevention - American Family Physician

May 15, 2018 - Colorectal cancer is a common cause of morbidity and mortality in the United States. Most colorectal cancers arise from preexisting adenomatous or serrated polyps. The incidence and mortality of colorectal cancer can be reduced with screening of average-risk adults 50 to 75 years of ...

American Family Physician : Article

https://www.aafp.org/afp/2018/0515/p658.html

Evaluation of the Solitary Pulmonary Nodule - American Family Physician

Dec 15, 2015 - A solitary pulmonary nodule is a common radiologic finding that is often discovered incidentally and may require significant workup to establish a definitive diagnosis. A solitary pulmonary nodule is a well-circumscribed round lesion measuring up to 3 cm in diameter and surrounded by ...

American Family Physician : Article

https://www.aafp.org/afp/2015/1215/p1084.html

Signs and Symptoms of Childhood Cancer: A Guide for Early Recognition - American Family...

Aug 1, 2013 - Although cancer in children is rare, it is the second most common cause of childhood mortality in developed countries. It often presents with nonspecific symptoms similar to those of benign conditions, leading to delays in the diagnosis and initiation of appropriate treatment. Primary ...

American Family Physician : Article

https://www.aafp.org/afp/2013/0801/p185.html

Prostate Cancer Screening - American Family Physician

Oct 15, 2015 - Among American men, prostate cancer is the most commonly diagnosed cancer and the second leading cause of cancer-related death. Although prostate-specific antigen (PSA) testing has been used to screen for prostate cancer for more than 25 years, the test has low sensitivity and ...

American Family Physician : Article

https://www.aafp.org/afp/2015/1015/p683.html

Cancer Screening in Older Patients - American Family Physician

Apr 15, 2016 - Although cancer is the second leading cause of death among persons 65 years and older, there is a paucity of clinical trial data about the effectiveness and harms of cancer screening in this population. Given the heterogeneous nature of the older population, cancer screening in these ...

American Family Physician : Article

https://www.aafp.org/afp/2016/0415/p659.html

Screening for Cancer: Concepts and Controversies - American Family Physician

Nov 1, 2014 - Early detection of cancer is a core task in family medicine, and patients have come to expect screening tests, sometimes out of proportion to what evidence can justify. To understand the controversies surrounding screening and to provide sound advice to patients, family physicians ...

American Family Physician : Article

https://www.aafp.org/afp/2014/1101/p625.html

Breast Cancer Screening Update - American Family Physician

Feb 15, 2013 - Breast cancer is the most common non–skin cancer and the second leading cause of cancer death in North American women. Mammography is the only screening test shown to reduce breast cancer–related mortality. There is general agreement that screening should be offered at least biennially ...

American Family Physician : Article

https://www.aafp.org/afp/2013/0215/p274.html

Colorectal Cancer Screening: ACP Guidance Statements - Practice Guidelines - American ... Restricted content. Login required.

Aug 15, 2020 - The American College of Physicians developed a consensus statement for colorectal cancer screening of average-risk adults based on their review of six independent guidelines and supporting evidence.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2020/0815/p250.html

Update on ASCCP Consensus Guidelines for Abnormal Cervical Screening Tests and Cervical...

Jul 15, 2009 - New data have emerged since publication of the American Society for Colposcopy and Cervical Pathology's 2001 consensus guidelines for management of abnormal cervical cytology and histology. The 2006 guidelines include recommendations for special populations (i.e., adolescents and ...

American Family Physician : Article

https://www.aafp.org/afp/2009/0715/p147.html

Breast Cancer Screening: ACP Releases Guidance Statements - Practice Guidelines - ... Restricted content. Login required.

Feb 1, 2020 - The American College of Physicians reviewed guidelines from other organizations and developed four statements to provide advice to clinicians about breast cancer screening for women who are at average risk.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2020/0201/p184.html

Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer: ...

Feb 15, 2020 - The USPSTF recommends that primary care clinicians assess women with a personal or family history of breast, ovarian, tubal, or peritoneal cancer or who have an ancestry associated with breast cancer susceptibility 1 and 2 (BRCA1/2) gene mutations with an appropriate brief familial risk...

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2020/0215/p233.html

Colorectal Cancer Screening: BMJ Rapid Recommendation - Practice Guidelines - American ... Restricted content. Login required.

Aug 15, 2020 - Colorectal cancer (CRC) screening recommendations vary because the underlying evidence is low quality, with few screening methods evaluated by randomized trials. The BMJ/MAGIC Group performed a systematic review based on 15-year CRC risk models to compare screening options.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2020/0815/p253.html

Keratinocyte Carcinomas: Should We Screen for Them? - Editorials - American Family ...

Sep 15, 2020 - Keratinocyte carcinoma, which includes basal cell and cutaneous squamous cell carcinomas, is common, and the incidence is increasing.

American Family Physician : Editorials

https://www.aafp.org/afp/2020/0915/p330.html

Mailing gFOBT or FIT Directly to Patients Increases Uptake of Colorectal Cancer ... Restricted content. Login required.

Jul 15, 2020 - Mailed outreach significantly increases rates of colorectal cancer screening, with four tests needing to be mailed to screen one person.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0715/p117.html

PAULA’s Test for Lung Cancer Screening - Diagnostic Tests: What Physicians Need to Know... Restricted content. Login required.

Jul 1, 2020 - Because of insufficient evidence of benefit, no recommendations can be made regarding PAULA's test. Prospective cohort studies of a screening population and randomized controlled trials comparing cancer mortality outcomes using PAULA's test vs. low-dose CT and no screening are needed ...

American Family Physician : Diagnostic Tests: What Physicians Need to Know

https://www.aafp.org/afp/2020/0701/p53.html

Supplemental MRI Screening in Women with Very Dense Breasts Reduces Interval Cancer ... Restricted content. Login required.

Jun 1, 2020 - Supplemental MRI screening for women with very dense breasts compared with mammography alone every two years significantly reduces the likelihood of an interval cancer, from 5 per 1,000 to 2.5 per 1,000 in the intention-to-treat population and to 0.8 per 1,000 in the per-protocol ...

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0601/p695a.html

Recognizing Neoplastic Skin Lesions: A Photo Guide - American Family Physician

Sep 15, 1998 - Malignant lesions of the skin are common. Patients who develop squamous cell carcinoma and malignant melanoma often have recognizable precursor conditions. A few skin lesions resemble malignancies. Lesions that are growing, spreading or pigmented, or those that occur on exposed areas of...

American Family Physician : Article

https://www.aafp.org/afp/1998/0915/p873.html

Integrating Breast Cancer Risk Management into Primary Care - Editorials - American ...

Mar 15, 2020 - It is important that primary care physicians have the ability and resources to identify women eligible for genetic counseling and testing for breast cancer.

American Family Physician : Editorials

https://www.aafp.org/afp/2020/0315/p330.html

Results of Fecal Immunochemical Tests for Colorectal Cancer Screening Not Affected by ... Restricted content. Login required.

Apr 1, 2020 - The use of aspirin, NSAIDs, and oral anticoagulants has no clinically important effects on the positive predictive value of FIT in a screening population.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0401/p435.html

Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer - ... Restricted content. Login required.

Feb 15, 2020 - A 31-year-old woman presents to your office for a well-woman examination. She is sexually active in a monogamous relationship and has never been pregnant. She tells you that her mother was diagnosed with tubal cancer at age 40 and that her sister, who is 42 years of age, was recently ...

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2020/0215/p239.html

Screening for Pancreatic Cancer - Putting Prevention into Practice - American Family ... Restricted content. Login required.

Dec 15, 2019 - A 71-year-old woman comes to your office for a regularly scheduled visit. She has type 2 diabetes mellitus and a 50-pack-year smoking history, and had non-ulcer dyspepsia two years ago. Her body mass index is 32 kg per m2, and her blood pressure is normal.

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2019/1215/p771.html

Screening for Pancreatic Cancer: Recommendation Statement - U.S. Preventive Services ...

Dec 15, 2019 - The USPSTF recommends against screening for pancreatic cancer in asymptomatic adults.

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2019/1215/od1.html

Adding Ultrasonography to Mammography Increases False-Positive Findings Without an ... Restricted content. Login required.

Jan 1, 2020 - Adding ultrasonography to screening mammography in women younger than 50 years at low, intermediate, or high breast cancer risk is not associated with an increase in breast cancer detection. It is associated with increased unnecessary biopsy recommendations and results in more frequent ...

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0101/p53a.html

Screening for Cervical Cancer: Recommendation Statement - U.S. Preventive Services Task...

Feb 15, 2019 - The USPSTF recommends screening for cervical cancer every 3 years with cervical cytology alone in women aged 21 to 29 years. For women aged 30 to 65 years, the USPSTF recommends screening every 3 years with cervical cytology alone, every 5 years with high-risk human papillomavirus ...

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2019/0215/od1.html

Lymphadenopathy and Malignancy - American Family Physician

Dec 1, 2002 - The majority of patients presenting with peripheral lymphadenopathy have easily identifiable causes that are benign or self-limited. Among primary care patients presenting with lymphadenopathy, the prevalence of malignancy has been estimated to be as low as 1.1 percent. The critical ...

American Family Physician : Article

https://www.aafp.org/afp/2002/1201/p2103.html

Prolaris Test for Prostate Cancer Risk Assessment - Diagnostic Tests: What Physicians ...

Sep 1, 2019 - The Prolaris test improves the accuracy of prognosis for patients with prostate cancer, especially those with low- or intermediate-grade disease who may be deciding between interventional and noninterventional treatment approaches.

American Family Physician : Diagnostic Tests: What Physicians Need to Know

https://www.aafp.org/afp/2019/0901/p311.html

mSEPT9 (Epi proColon) Blood Test for Colorectal Cancer Screening - Diagnostic Tests: ...

Jul 1, 2019 - Epi proColon is a blood test used for the detection of the methylated septin 9 (mSEPT9) gene. It is approved by the U.S. Food and Drug Administration for colorectal cancer screening in people at average risk who have declined first-line screening tests.

American Family Physician : Diagnostic Tests: What Physicians Need to Know

https://www.aafp.org/afp/2019/0701/p10.html

Lung Cancer Screening: Pros and Cons - Lown Right Care: Reducing Overuse and Underuse -...

Jun 15, 2019 - A collaboration between AFP and the Lown Institute promotes a vision of delivering heath care that is based on the evidence, balanced in its approach, and focused on the patient.

American Family Physician : Lown Right Care: Reducing Overuse and Underuse

https://www.aafp.org/afp/2019/0615/p740.html

Screening for Cervical Cancer - Putting Prevention into Practice - American Family ...

Feb 15, 2019 - P.J., a 48-year-old woman, presents to your office for a well-woman examination. She has been married for eight years, has no history of sexually transmitted diseases, and has nothing remarkable in her medical history.

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2019/0215/p253.html

Lung Cancer Screening Recommendations from the ACCP - Practice Guidelines - American ...

Dec 1, 2018 - The American College of Chest Physicians (ACCP) recently published recommendations for lung cancer screening based on key questions developed using the PICO (population, intervention, comparator, and outcome) format.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2018/1201/p688.html

Flexible Sigmoidoscopy or Fecal Occult Blood Testing for Colorectal Cancer Screening in...

Aug 1, 2019 - This meta-analysis provides high-quality evidence that flexible sigmoidoscopy and fecal occult blood testing both reduce the risk of death from colorectal cancer. The study did not provide a clear answer regarding a superior screening modality, so the decision to choose one test over ...

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2019/0801/od1.html

Cancer Screening: ACS Releases Annual Summary of Recommendations - Practice Guidelines ...

Jun 1, 2019 - The American Cancer Society (ACS) provides a summary of recommendations for cancer screening each year, including any updates and recent data, and advice for when recommendations cannot be made.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2019/0601/p719.html

Colorectal Cancer Screening: ACS Updates Guideline for Adults with Average Risk - ...

Jan 15, 2019 - To support early identification and treatment, the American Cancer Society (ACS) has updated its 2008 guidance on counseling and referring patients at average risk of colorectal cancer (CRC) based on new evidence regarding screening options and the ever-changing risk of CRC.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2019/0115/p129.html

FIT Has Similar Yield as Colonoscopy for Colorectal Cancer and Advanced Adenoma Over 10...

May 15, 2019 - Over a 10-year period, the rates of detection of colorectal cancer (CRC) and advanced adenomas using FIT are similar to those seen in studies of screening colonoscopy. This does not prove that FIT reduces morbidity and mortality due to CRC as effectively as colonoscopy.

American Family Physician : POEMs

https://www.aafp.org/afp/2019/0515/od5.html

Counseling Patients About Prostate Cancer Screening - Editorials - American Family ...

Oct 15, 2018 - The AAFP finds that the net benefit of population screening for prostate cancer is small at best, and it does not recommend routinely discussing PSA-based screening if the patient does not request it.

American Family Physician : Editorials

https://www.aafp.org/afp/2018/1015/p478.html

Stumbling onto Cancer: Avoiding Overdiagnosis of Renal Cell Carcinoma - Editorials - ...

Feb 1, 2019 - We all need to test wisely and weigh the risks and benefits of diagnostic imaging. Imaging—and testing in general—has real downsides, such as stumbling onto things you wish you had not.

American Family Physician : Editorials

https://www.aafp.org/afp/2019/0201/p145.html

Breast Cancer Screening with MRI: More False-Positives, More Biopsies - POEMs - ...

Nov 15, 2018 - Screening with MRI is not for everyone. Women who undergo breast cancer screening with MRI are much more likely to be referred for biopsy— that will ultimately be negative—than if they have screening mammography alone.

American Family Physician : POEMs

https://www.aafp.org/afp/2018/1115/od5.html

Cancer Screening Recommendations from the ACS: A Summary of the 2017 Guidelines - ...

Feb 1, 2018 - Each year, the American Cancer Society (ACS) releases guidelines for health care professionals and patients on current cancer screening recommendations. The annual report updates previous recommendations, provides data on cancer screening rates, and discusses issues relating to early ...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2018/0201/p208.html

Screening for Prostate Cancer - Putting Prevention into Practice - American Family ...

Oct 15, 2018 - A.E., a 57-year-old black man, comes to your office for an annual visit. He has a history of diabetes mellitus, has never smoked, and has no family history of prostate cancer. He is current with preventive services, including screening for colorectal cancer and counseling for a healthy ...

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2018/1015/p537.html

Screening for Prostate Cancer: Recommendation Statement - U.S. Preventive Services Task...

Oct 15, 2018 - Advertisement << Previous article Next article >> Oct 15, 2018 Issue U.S. Preventive Services Task Force Screening for Prostate Cancer: Recommendation Statement Am Fam Physician. 2018 Oct 15;98(8):online. Related Putting Prevention into Practice: Screening for Prostate Cancer...

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2018/1015/od1.html

HPV Testing Better Than Cytology for Women Vaccinated Against HPV - POEMs - American ...

Sep 15, 2018 - In women who had received the HPV vaccine, screening for HPV every five years, with cytology and colposcopy follow-up as needed, resulted in higher rates of identification of high-grade pre-cancerous disease than standard liquid-based cytology every 2.5 years with HPV follow-up ...

American Family Physician : POEMs

https://www.aafp.org/afp/2018/0915/p384.html

Screening for Ovarian Cancer: Recommendation Statement - U.S. Preventive Services Task ...

Jun 15, 2018 - The USPSTF recommends against screening for ovarian cancer in asymptomatic women.

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2018/0615/od1.html

Colorectal Cancer: A Summary of the Evidence for Screening and Prevention - American ...

Dec 15, 2008 - Colorectal cancer causes significant morbidity and mortality in the United States. The incidence of colorectal cancer can be reduced with increasing efforts directed at mass screening of average-risk adults 50 years and older. Currently, fecal occult blood test and flexible ...

American Family Physician : Article

https://www.aafp.org/afp/2008/1215/p1385.html

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