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Fecal Occult Blood Testing Is Inaccurate as Part of Diagnostic Workup - POEMs - ... Restricted content. Login required.

Dec 1, 2020 - In this well-conducted systematic review, FOBT, although useful in screening for colorectal cancer, is not highly accurate in evaluating patients with clinical indications.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/1201/p692.html

Fewer Major Bleeds with Edoxaban Than with Warfarin, but Treatment Benefit Unclear - ...

May 15, 2014 - Edoxaban provides similar effectiveness and a somewhat lower rate of major gastrointestinal and intracranial bleeding than warfarin. It is worth reading the supplemental appendices to this report for a look at the subgroups. For almost all subgroups, low-dose edoxaban caused less major ...

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0515/p827.html

Greater Benefit with Rivaroxaban Than Aspirin for Extended Treatment of VTE - POEMs - ...

Jul 15, 2017 - Compared with aspirin, the use of rivaroxaban (Xarelto) to extend anticoagulation beyond the initial six to 12 months to treat provoked or unprovoked VTE reduces the risk of recurrent symptomatic VTE without increasing the risk of bleeding. You would need to treat approximately 30 to 33...

American Family Physician : POEMs

https://www.aafp.org/afp/2017/0715/p128.html

Hemolytic Anemia - American Family Physician

Jun 1, 2004 - Hemolysis presents as acute or chronic anemia, reticulocytosis, or jaundice. The diagnosis is established by reticulocytosis, increased unconjugated bilirubin and lactate dehydrogenase, decreased haptoglobin, and peripheral blood smear findings. Premature destruction of erythrocytes ...

American Family Physician : Article

https://www.aafp.org/afp/2004/0601/p2599.html

Hemolytic Anemia: Evaluation and Differential Diagnosis - American Family Physician

Sep 15, 2018 - Hemolytic anemia is defined by the premature destruction of red blood cells, and can be chronic or life-threatening. It should be part of the differential diagnosis for any normocytic or macrocytic anemia. Hemolysis may occur intravascularly, extravascularly in the reticuloendothelial ...

American Family Physician : Article

https://www.aafp.org/afp/2018/0915/p354.html

Hemolytic Uremic Syndrome: An Emerging Health Risk - American Family Physician

Sep 15, 2006 - Hemolytic uremic syndrome is caused primarily by Shiga toxin-producing Escherichia coli O157:H7. The most common cause of acute renal failure in children, hemolytic uremic syndrome also can occur in adults. Characteristic features of the syndrome are microangiopathic anemia, thrombotic ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0915/p991.html

Henoch-Schönlein Purpura - American Family Physician

Oct 1, 2009 - Henoch-Schönlein purpura is an acute, systemic, immune complex-mediated, leukocytoclastic vasculitis. It is characterized by a triad of palpable purpura (without thrombocytopenia), abdominal pain, and arthritis. Most patients have an antecedent upper respiratory illness. More than 90 ...

American Family Physician : Article

https://www.aafp.org/afp/2009/1001/p697.html

Henoch-Schönlein Purpura: A Review - American Family Physician

Aug 1, 1998 - Henoch-Schönlein purpura is an IgA-mediated, autoimmune, hypersensitivity vasculitis of childhood that results in a triad of symptoms, including a purpuric rash occurring on the lower extremities, abdominal pain or renal involvement, and arthritis. However, any of the triad may be ...

American Family Physician : Article

https://www.aafp.org/afp/1998/0801/p405.html

Hereditary Hemochromatosis - American Family Physician

Feb 1, 2013 - Hereditary hemochromatosis is an autosomal recessive disorder that disrupts the body’s regulation of iron. It is the most common genetic disease in whites. Men have a 24-fold increased rate of iron-overload disease compared with women. Persons who are homozygous for the HFE gene ...

American Family Physician : Article

https://www.aafp.org/afp/2013/0201/p183.html

Hereditary Hemorrhagic Telangiectasia: Diagnosis and Management - American Family ...

Oct 1, 2010 - Hereditary hemorrhagic telangiectasia is an uncommon autosomal dominant disease that occurs in approximately one in 5,000 to 8,000 persons. This multisystem disorder can affect the nose, skin, gastrointestinal tract, lungs, liver, and brain. Epistaxis is the most common presenting ...

American Family Physician : Article

https://www.aafp.org/afp/2010/1001/p785.html

High-Dose vs. Standard-Dose Heparin for VTE Prophylaxis in Obese Patients - FPIN's Help...

Jun 1, 2018 - In most patients weighing more than 220 lb (100 kg), high-dose heparin prophylaxis (7,500 units subcutaneously three times per day) does not further reduce the risk of VTE compared with standard-dose heparin (5,000 units subcutaneously two or three times per day).

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2018/0601/od2.html

Idarucizumab (Praxbind) for Dabigatran (Pradaxa) Anticoagulant Reversal - STEPS - ...

Jun 15, 2017 - Idarucizumab is the only anticoagulant reversal agent for dabigatran. Because of its high cost and limited data regarding clinical benefit, therapy should be reserved for patients taking dabigatran who have life-threatening bleeding or are in need of emergency surgery.

American Family Physician : STEPS

https://www.aafp.org/afp/2017/0615/p798.html

Iron Deficiency and Other Types of Anemia in Infants and Children - American Family ...

Feb 15, 2016 - Anemia, defined as a hemoglobin level two standard deviations below the mean for age, is prevalent in infants and children worldwide. The evaluation of a child with anemia should begin with a thorough history and risk assessment. Characterizing the anemia as microcytic, normocytic, or ...

American Family Physician : Article

https://www.aafp.org/afp/2016/0215/p270.html

Iron Deficiency Anemia - American Family Physician

Mar 1, 2007 - The prevalence of iron deficiency anemia is 2 percent in adult men, 9 to 12 percent in non-Hispanic white women, and nearly 20 percent in black and Mexican-American women. Nine percent of patients older than 65 years with iron deficiency anemia have a gastrointestinal cancer when ...

American Family Physician : Article

https://www.aafp.org/afp/2007/0301/p671.html

Iron Deficiency Anemia: Evaluation and Management - American Family Physician

Jan 15, 2013 - Iron deficiency is the most common nutritional disorder worldwide and accounts for approximately one-half of anemia cases. The diagnosis of iron deficiency anemia is confirmed by the findings of low iron stores and a hemoglobin level two standard deviations below normal. Women should be...

American Family Physician : Article

https://www.aafp.org/afp/2013/0115/p98.html

Is Rivaroxaban Noninferior to Standard Warfarin Therapy in Preventing Recurrent PE and ...

Jun 15, 2013 - A trial showing that one drug is noninferior to another does not mean that these drugs are equivalent. The noninferiority margin allows researchers to choose their own benchmark for what is considered a clinically significant difference between two drugs.

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2013/0615/p872.html

Is Unfractionated Heparin Equivalent to Low-Molecular-Weight Heparin for Venous ...

Jun 1, 2008 - Is weight-based unfractionated heparin as good as weight-based low-molecular-weight heparin for outpatient treatment of venous thromboembolism? Even though this study was underpowered to prove equivalence, treatment with subcutaneous unfractionated heparin is a viable option.

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2008/0601/p1492.html

Leukemia: An Overview for Primary Care - American Family Physician

May 1, 2014 - Leukemia is a clonal proliferation of hematopoietic stem cells in the bone marrow. The four broad subtypes most likely to be encountered by primary care physicians are acute lymphoblastic, acute myelogenous, chronic lymphocytic, and chronic myelogenous. Acute lymphoblastic leukemia ...

American Family Physician : Article

https://www.aafp.org/afp/2014/0501/p731.html

Leukocytosis: Basics of Clinical Assessment - American Family Physician

Nov 1, 2000 - Leukocytosis, a common laboratory finding, is most often due to relatively benign conditions (infections or inflammatory processes). Much less common but more serious causes include primary bone marrow disorders. The normal reaction of bone marrow to infection or inflammation leads to ...

American Family Physician : Article

https://www.aafp.org/afp/2000/1101/p2053.html

Low-Molecular Weight Heparin in Preventing and Treating DVT - American Family Physician

Mar 15, 1999 - Low-molecular-weight heparin is a relatively recent addition to the list of therapies for prophylaxis and treatment of deep venous thrombosis (DVT). As a prophylactic, low-molecular-weight heparin is as effective as standard heparin or warfarin and does not require monitoring of the ...

American Family Physician : Article

https://www.aafp.org/afp/1999/0315/p1607.html

Low-Molecular-Weight Heparin for Initial Treatment of Venous Thromboembolism - Cochrane...

Jul 1, 2005 - LMWH is safer and more effective than unfractionated heparin for initial treatment of venous thromboembolism.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/0701/p75.html

Low-Molecular-Weight Heparin in Treatment of DVT - American Family Physician

Feb 15, 1999 - Patients with a diagnosis of acute deep venous thrombosis have traditionally been hospitalized and treated with unfractionated heparin followed by oral anticoagulation therapy. Several clinical trials have shown that low-molecular-weight heparin is at least as safe and effective as ...

American Family Physician : Article

https://www.aafp.org/afp/1999/0215/p945.html

Lymphadenopathy: Differential Diagnosis and Evaluation - American Family Physician

Oct 15, 1998 - Although the finding of lymphadenopathy sometimes raises fears about serious illness, it is, in patients seen in primary care settings, usually a result of benign infectious causes. Most patients can be diagnosed on the basis of a careful history and physical examination. Localized ...

American Family Physician : Article

https://www.aafp.org/afp/1998/1015/p1313.html

Lymphoma: Diagnosis and Treatment - American Family Physician

Jan 1, 2020 - Lymphoma is a group of malignant neoplasms of lymphocytes with more than 90 subtypes. It is traditionally classified broadly as non-Hodgkin or Hodgkin lymphoma. Approximately 82,000 new U.S. patients are diagnosed with lymphoma annually. Any tobacco use and obesity are major modifiable ...

American Family Physician : Article

https://www.aafp.org/afp/2020/0101/p34.html

Management of Sickle Cell Disease: Recommendations from the 2014 Expert Panel Report - ...

Dec 15, 2015 - Family physicians are the primary and sometimes only health care resource for families affected by sickle cell disease. Recently published guidelines provide important recommendations for health maintenance, acute care, and monitoring of disease-modifying therapy in persons with this ...

American Family Physician : Article

https://www.aafp.org/afp/2015/1215/p1069.html

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