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New Anticoagulants vs. Warfarin in Atrial Fibrillation: No Clear Winner - POEMs - ...

Jul 15, 2014 - In this meta-analysis, newer anticoagulants appear to be slightly more effective than warfarin in the short term (two years) in preventing strokes of all kinds in patients with atrial fibrillation. However, they are no more effective than warfarin in preventing ischemic strokes, and ...

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0715/p110a.html

Normocytic Anemia - American Family Physician

Nov 15, 2000 - Anemia is a common problem that is often discovered on routine laboratory tests. Its prevalence increases with age, reaching 44 percent in men older than 85 years. Normocytic anemia is the most frequently encountered type of anemia. Anemia of chronic disease, the most common normocytic ...

American Family Physician : Article

https://www.aafp.org/afp/2000/1115/p2255.html

NPMS Releases Consensus Statement on Venous Thromboembolism During Pregnancy - Practice...

Mar 15, 2017 - The main strategy for preventing VTE-related mortality is thromboprophylaxis, but guidance regarding its use differs across specialties and organizations. For this reason, the National Partnership for Maternal Safety (NPMS), a group made up of a variety of leaders in women's health ...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2017/0315/p397.html

Opportunities to Improve Outcomes in Sickle Cell Disease - American Family Physician

Jul 15, 2006 - Sickle cell disease represents a spectrum of inherited hemoglobin disorders. The pathophysiology involves abnormalities not just in red blood cells but also vascular endothelium, white blood cell function, coagulation, and inflammatory response. Known sequelae of sickle cell disease ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0715/p303.html

Optimal Treatment of Acute Venous Thromboembolism - POEMs - American Family Physician

Apr 1, 2015 - This complex network meta-analysis of eight treatment regimens for acute venous thromboembolism found that a combination of unfractionated heparin and vitamin K antagonists is associated with the least effective strategy with the highest risk of recurrent events.

American Family Physician : POEMs

https://www.aafp.org/afp/2015/0401/p492.html

Oral Anticoagulants vs. Antiplatelet Therapy - Cochrane for Clinicians - American ...

May 1, 2008 - Compared with antiplatelet therapy, oral anticoagulation significantly reduces stroke at an average follow-up of one to three years, but does not reduce mortality. Intracranial or extracranial hemorrhage is more common with anticoagulation and must be weighed against its therapeutic ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2008/0501/p1250.html

Outpatient Management of Anticoagulation Therapy - American Family Physician

Apr 1, 2007 - The Seventh American College of Chest Physicians (ACCP) Conference on Antithrombotic and Thrombolytic Therapy provides guidelines for outpatient management of anticoagulation therapy. The ACCP guidelines recommend short-term warfarin therapy, with the goal of maintaining an ...

American Family Physician : Article

https://www.aafp.org/afp/2007/0401/p1031.html

Patients with Initial Unprovoked DVT or PE Benefit from Long-Term Low-Dose Aspirin - ...

Jun 15, 2015 - Aspirin improves long-term cardiovascular and thrombotic outcomes in patients who have had an initial unprovoked episode of VTE. The risk of bleeding was no higher in the aspirin group, perhaps because those at risk of bleeding were uncovered during the initial period of anticoagulation.

American Family Physician : POEMs

https://www.aafp.org/afp/2015/0615/p872.html

Perioperative Bridging Anticoagulation Unhelpful for Invasive Procedures - POEMs - ...

Jan 15, 2016 - Bridging anticoagulation worsens outcomes for patients with atrial fibrillation who undergo an elective invasive procedure, resulting in more episodes of major bleeding and no difference in the rate of stroke or venous thromboembolism.

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0115/p130.html

Pneumatic Compression in Addition to Pharmacologic Thromboprophylaxis Does Not Further ...

Oct 1, 2019 - This study found no benefit to the addition of intermittent pneumatic compression to pharmacologic anticoagulation for the prevention of proximal DVT in critically ill patients.

American Family Physician : POEMs

https://www.aafp.org/afp/2019/1001/p440a.html

Polycythemia Vera - American Family Physician

May 1, 2004 - Polycythemia vera is a chronic myeloproliferative disorder characterized by increased red blood cell mass. The resultant hyperviscosity of the blood predisposes such patients to thrombosis. Polycythemia vera should be suspected in patients with elevated hemoglobin or hematocrit levels, ...

American Family Physician : Article

https://www.aafp.org/afp/2004/0501/p2139.html

Predicting the Risk of Bleeding in Patients Taking Warfarin - Point-of-Care Guides - ...

Mar 15, 2010 - When considering anticoagulation therapy in patients with atrial fibrillation or venous thromboembolism (VTE), physicians and patients must balance the benefits of anticoagulation with the risk of bleeding, particularly major bleeding complications. For example, in patients who are at ...

American Family Physician : Point-of-Care Guides

https://www.aafp.org/afp/2010/0315/p780.html

Real-World Study Finds Lower Mortality and Stroke Risk with Dabigatran, but More GI ...

Sep 15, 2015 - In this well-designed observational study, older patients given an initial prescription of dabigatran had lower all-cause mortality and fewer ischemic and hemorrhagic strokes, but a higher risk of gastrointestinal (GI) bleeding, than a matched group of patients given warfarin.

American Family Physician : POEMs

https://www.aafp.org/afp/2015/0915/p529.html

Recognition and Management of Hereditary Hemochromatosis - American Family Physician

Mar 1, 2002 - Hereditary hemochromatosis is the most common inherited single-gene disorder in people of northern European descent. It is characterized by increased intestinal absorption of iron, with deposition of the iron in multiple organs. Previously, the classic description was combined diabetes ...

American Family Physician : Article

https://www.aafp.org/afp/2002/0301/p853.html

Recurrent Venous Thromboembolism - American Family Physician

Feb 1, 2011 - A previous venous thromboembolism is the most important risk factor for predicting recurrence of the condition. Several studies have shown that routine testing for inherited thrombophilias is not helpful in predicting the risk of recurrence or altering treatment decisions, and therefore...

American Family Physician : Article

https://www.aafp.org/afp/2011/0201/p293.html

Risk of GI Bleeding Highest with Rivaroxaban, Lower with Apixaban, and Lowest with PPI ...

May 15, 2019 - Among patients using oral anticoagulants alone, the risk of hospitalization for upper GI tract bleeding is highest with rivaroxaban (Xarelto) and lowest with apixaban (Eliquis).

American Family Physician : POEMs

https://www.aafp.org/afp/2019/0515/od4.html

Rivaroxaban vs. Warfarin for Treatment of DVT and PE - FPIN's Clinical Inquiries - ...

Oct 15, 2017 - Rivaroxaban, along with the other factor Xa inhibitors, is as effective as or better in the short term (three months) than warfarin (Coumadin) for preventing recurrent DVT, nonfatal PE, and fatal PE, with no differences in mortality or bleeding events.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2017/1015/p532.html

Screening for Hemochromatosis: Recommendation Statement - U.S. Preventive Services Task...

Jun 1, 2007 - This statement summarizes the U.S. Preventive Services Task Force (USPSTF) recommendations on screening for hemochromatosis and the supporting scientific evidence.

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2007/0601/p1696.html

Screening for Iron Deficiency Anemia and Iron Supplementation in Pregnant Women to ...

Jan 15, 2016 - A 28-year-old woman presents for a routine antepartum visit. She is 33 weeks pregnant and also has a four-year-old son. She has no particular problems, and the findings from your examination are unremarkable. She asks if her blood iron level should be tested.

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2016/0115/p137.html

Screening for Iron Deficiency Anemia and Iron Supplementation in Pregnant Women to ...

Jan 15, 2016 - The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for iron deficiency anemia in pregnant women to prevent adverse maternal health and birth outcomes.

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2016/0115/p133.html

Screening for Iron Deficiency Anemia in Young Children - Putting Prevention into ...

Dec 15, 2015 - C.C., a 32-year-old white woman, presents to your office with her nine-month-old son for a routine well-child visit. She is preparing to switch him from breast milk to formula and had noted that most formulas contain iron. She wonders if her son should be screened for iron deficiency ...

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2015/1215/p1103.html

Screening for Iron Deficiency Anemia in Young Children: Recommendation Statement - U.S....

Dec 15, 2015 - The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for iron deficiency anemia in children ages 6 to 24 months.

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2015/1215/od1.html

Screening for Iron Deficiency Anemia, Including Iron Supplementations for Children and ...

Aug 1, 2006 - This statement summarizes the U.S. Preventive Services Task Force (USPSTF) recommendations on screening for iron deficiency anemia and the supporting scientific evidence.

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2006/0801/p461.html

Self-Monitoring and Self-Management of Oral Anticoagulation - Cochrane for Clinicians -...

Jun 1, 2017 - In patients taking warfarin (Coumadin) for anticoagulation, there is moderate-quality evidence that both self-monitoring (number needed to treat [NNT] = 100) and self-management (NNT = 53) reduce thromboembolic events, and that self-management reduces all-cause mortality (NNT = 67).

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2017/0601/p700.html

Sickle Cell Disease in Childhood: Part I. Laboratory Diagnosis, Pathophysiology and ...

Sep 1, 2000 - Over the past 25 years, morbidity and mortality have decreased significantly in children with sickle cell disease, and screening tests are now available to diagnose the disease in newborns. The incidence of sepsis caused by pneumococcal and Haemophilus influenzae infections has declined...

American Family Physician : Article

https://www.aafp.org/afp/2000/0901/p1013.html

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