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Sickle Cell Disease in Childhood: Part II. Diagnosis and Treatment of Major ...

Sep 15, 2000 - Treatment advances over the past 25 years have significantly decreased morbidity and mortality in children with sickle cell disease. Aggressive management of fever, early diagnosis of acute chest syndrome, judicious use of transfusions and proper treatment of pain can improve quality of...

American Family Physician : Article

https://www.aafp.org/afp/2000/0915/p1309.html

Systemic Vasculitis - American Family Physician

Mar 1, 2011 - The systemic vasculitides are characterized by inflammation of blood vessel walls. Vessels of any type, in any organ can be affected, resulting in a broad spectrum of signs and symptoms. The heterogenous nature of vasculitides presents a diagnostic challenge. The American College of ...

American Family Physician : Article

https://www.aafp.org/afp/2011/0301/p556.html

Thrombocytopenia - American Family Physician

Mar 15, 2012 - Thrombocytopenia is defined as a platelet count of less than 150 × 103 per µL. It is often discovered incidentally when obtaining a complete blood count during an office visit. The etiology usually is not obvious, and additional investigation is required. Patients with platelet counts ...

American Family Physician : Article

https://www.aafp.org/afp/2012/0315/p612.html

Thromboembolism - Clinical Evidence Handbook - American Family Physician

Jan 15, 2012 - What are the effects of treatments for proximal and isolated calf DVT? What are the effects of treatments for pulmonary embolism? What are the effects of interventions on oral anticoagulation management in persons with thromboembolism?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2012/0115/p188.html

Thromboembolism - Clinical Evidence Handbook - American Family Physician

Jan 1, 2004 - What are the effects of treatments for proximal deep venous thrombosis? What are the effects of treatments for isolated calf venous thrombosis? What are the effects of treatments for pulmonary embolism? What are the effects of computerized decision support on oral anticoagulation ...

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2004/0101/p132.html

Thromboembolism Recurrence Likely; Consider It a Chronic Disease - POEMs - American ... Restricted content. Login required.

Mar 1, 2020 - Perhaps it is time to start thinking about VTE as a chronic disease. Approximately one in 10 patients that have a VTE will have a second VTE over the next 12 months and almost four in 10 will have a second VTE over 10 years.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0301/p309.html

Thrombolysis for DVT: Has the Time Arrived? - AFP Journal Club - American Family Physician

Apr 1, 2015 - Catheter-directed thrombolysis for proximal DVT is experimental but may be considered in a patient with phlegmasia and resulting compartment syndrome.

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2015/0401/p430.html

Tranexamic Acid for Postpartum Hemorrhage - Medicine by the Numbers - American Family ... Restricted content. Login required.

May 1, 2020 - Postpartum hemorrhage is the most common cause of maternal death worldwide. Tranexamic acid is an antifibrinolytic agent that has shown to decrease bleeding in surgical patients and all-cause death in trauma patients. Does early administration of tranexamic acid reduce the rate of death...

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2020/0501/od2.html

Transfusion of Blood and Blood Products: Indications and Complications - American ...

Mar 15, 2011 - Red blood cell transfusions are used to treat hemorrhage and to improve oxygen delivery to tissues. Transfusion of red blood cells should be based on the patient’s clinical condition. Indications for transfusion include symptomatic anemia (causing shortness of breath, dizziness, ...

American Family Physician : Article

https://www.aafp.org/afp/2011/0315/p719.html

Treatment of Calf Deep Venous Thrombosis - FPIN's Clinical Inquiries - American Family ...

Jun 1, 2005 - Patients with a first episode of calf DVT with a transient risk factor should receive heparin therapy followed by oral anticoagulation for six to 12 weeks.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2005/0601/p2157.html

Treatment of Distal DVT - Cochrane for Clinicians - American Family Physician Restricted content. Login required.

Jan 1, 2021 - Vitamin K antagonists reduce the recurrence of DVT and VTE (number needed to treat [NNT] = 17; 95% CI, 13 to 48) but not pulmonary embolism (PE) compared with no anticoagulation or placebo.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2021/0101/p18.html

Understanding and Interpreting the Serum Protein Electrophoresis - American Family ...

Jan 1, 2005 - Serum protein electrophoresis is used to identify patients with multiple myeloma and other serum protein disorders. Electrophoresis separates proteins based on their physical properties, and the subsets of these proteins are used in interpreting the results. Plasma protein levels ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0101/p105.html

Unexplained Lymphadenopathy: Evaluation and Differential Diagnosis - American Family ...

Dec 1, 2016 - Lymphadenopathy is benign and self-limited in most patients. Etiologies include malignancy, infection, and autoimmune disorders, as well as medications and iatrogenic causes. The history and physical examination alone usually identify the cause of lymphadenopathy. When the cause is ...

American Family Physician : Article

https://www.aafp.org/afp/2016/1201/p896.html

Update on Vitamin B12 Deficiency - American Family Physician

Jun 15, 2011 - Vitamin B12 (cobalamin) deficiency is a common cause of megaloblastic anemia, a variety of neuropsychiatric symp- toms, and elevated serum homocysteine levels, especially in older persons. There are a number of risk factors for vitamin B12 deficiency, including prolonged use of ...

American Family Physician : Article

https://www.aafp.org/afp/2011/0615/p1425.html

Updated Guidelines on Outpatient Anticoagulation - American Family Physician

Apr 15, 2013 - The American College of Chest Physicians provides recommendations for the use of anticoagulant medications for several indications that are important in the primary care setting. Warfarin, a vitamin K antagonist, is recommended for the treatment of venous thromboembolism and for the ...

American Family Physician : Article

https://www.aafp.org/afp/2013/0415/p556.html

Vitamin B12 Deficiency - American Family Physician

Mar 1, 2003 - Vitamin B12 (cobalamin) deficiency is a common cause of macrocytic anemia and has been implicated in a spectrum of neuropsychiatric disorders. The role of B12 deficiency in hyperhomocysteinemia and the promotion of atherosclerosis is only now being explored. Diagnosis of vitamin B12 ...

American Family Physician : Article

https://www.aafp.org/afp/2003/0301/p979.html

Vitamin B12 Deficiency: Recognition and Management - American Family Physician

Sep 15, 2017 - Vitamin B12 deficiency is a common cause of megaloblastic anemia, various neuropsychiatric symptoms, and other clinical manifestations. Screening average-risk adults for vitamin B12 deficiency is not recommended. Screening may be warranted in patients with one or more risk factors, such...

American Family Physician : Article

https://www.aafp.org/afp/2017/0915/p384.html

VTE in Patients with Cancer: Guidelines from the American Society of Clinical Oncology ... Restricted content. Login required.

Aug 1, 2020 - The American Society of Clinical Oncology has updated recommendations for the prevention and treatment of venous thromboembolism (VTE) in patients with cancer.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2020/0801/p188.html

Warfarin Therapy: Evolving Strategies in Anticoagulation - American Family Physician

Feb 1, 1999 - Warfarin is the oral anticoagulant most frequently used to control and prevent thromboembolic disorders. Prescribing the dose that both avoids hemorrhagic complications and achieves sufficient suppression of thrombosis requires a thorough understanding of the drug's unique pharmacology....

American Family Physician : Article

https://www.aafp.org/afp/1999/0201/p635.html

What Clinical Findings Can Be Used to Diagnose Deep Venous Thrombosis? - FPIN's ...

Aug 1, 2004 - No single clinical finding can accurately diagnose DVT.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2004/0801/p565.html

YEARS Clinical Decision Tool Decreases CTA in Patients with Suspected Pulmonary ...

Nov 15, 2017 - In this study, using a simplified algorithm in patients with suspected pulmonary embolism can safely decrease the number of CTAs.

American Family Physician : POEMs

https://www.aafp.org/afp/2017/1115/od3.html

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