Hemolytic Anemia: Evaluation and Differential Diagnosis - American Family Physician
Sep 15, 2018 - Hemolytic anemia is defined by the premature destruction of red blood cells, and can be chronic or life-threatening. It should be part of the differential diagnosis for any normocytic or macrocytic anemia. Hemolysis may occur intravascularly, extravascularly in the reticuloendothelial ...
American Family Physician : Article
https://www.aafp.org/afp/2018/0915/p354.html
Unexplained Lymphadenopathy: Evaluation and Differential Diagnosis - American Family ...
Dec 1, 2016 - Lymphadenopathy is benign and self-limited in most patients. Etiologies include malignancy, infection, and autoimmune disorders, as well as medications and iatrogenic causes. The history and physical examination alone usually identify the cause of lymphadenopathy. When the cause is ...
American Family Physician : Article
https://www.aafp.org/afp/2016/1201/p896.html
Evaluation of Patients with Leukocytosis - American Family Physician
Dec 1, 2015 - An elevated white blood cell count has many potential etiologies, including malignant and nonmalignant causes. It is important to use age- and pregnancy-specific normal ranges for the white blood cell count. A repeat complete blood count with peripheral smear may provide helpful ...
American Family Physician : Article
https://www.aafp.org/afp/2015/1201/p1004.html
Iron Deficiency and Other Types of Anemia in Infants and Children - American Family ...
Feb 15, 2016 - Anemia, defined as a hemoglobin level two standard deviations below the mean for age, is prevalent in infants and children worldwide. The evaluation of a child with anemia should begin with a thorough history and risk assessment. Characterizing the anemia as microcytic, normocytic, or ...
American Family Physician : Article
https://www.aafp.org/afp/2016/0215/p270.html
Anemia in Older Adults - American Family Physician
Oct 1, 2018 - Anemia is associated with increased morbidity and mortality in older adults. Diagnostic cutoff values for defining anemia vary with age, sex, and possibly race. Anemia is often asymptomatic and discovered incidentally on laboratory testing. Patients may present with symptoms related to ...
American Family Physician : Article
https://www.aafp.org/afp/2018/1001/p437.html
Clinical Evaluation of Bleeding and Bruising in Primary Care - American Family Physician
Feb 15, 2016 - Bleeding and bruising are common symptoms in the primary care setting. The patient history can help determine whether the bruising or bleeding is abnormal. The International Society on Thrombosis and Hemostasis has developed a bleeding assessment tool that can be used to indicate ...
American Family Physician : Article
https://www.aafp.org/afp/2016/0215/p279.html
Evaluation of Anemia in Children - American Family Physician
Jun 15, 2010 - Anemia is defined as a hemoglobin level of less than the 5th percentile for age. Causes vary by age. Most children with anemia are asymptomatic, and the condition is detected on screening laboratory evaluation. Screening is recommended only for high-risk children. Anemia is classified ...
American Family Physician : Article
https://www.aafp.org/afp/2010/0615/p1462.html
Evaluation of Microcytosis - American Family Physician
Nov 1, 2010 - Microcytosis is typically an incidental finding in asymptomatic patients who received a complete blood count for other reasons. The condition is defined as a mean corpuscular volume of less than 80 µm3 (80 fL) in adults. The most common causes of microcytosis are iron deficiency anemia ...
American Family Physician : Article
https://www.aafp.org/afp/2010/1101/p1117.html
Evaluation of Macrocytosis - American Family Physician
Feb 1, 2009 - Macrocytosis, generally defined as a mean corpuscular volume greater than 100 fL, is frequently encountered when a complete blood count is performed. The most common etiologies are alcoholism, vitamin B12 and folate deficiencies, and medications. History and physical examination, ...
American Family Physician : Article
https://www.aafp.org/afp/2009/0201/p203.html
Understanding and Interpreting the Serum Protein Electrophoresis - American Family ...
Jan 1, 2005 - Serum protein electrophoresis is used to identify patients with multiple myeloma and other serum protein disorders. Electrophoresis separates proteins based on their physical properties, and the subsets of these proteins are used in interpreting the results. Plasma protein levels ...
American Family Physician : Article
https://www.aafp.org/afp/2005/0101/p105.html
Bleeding and Bruising: A Diagnostic Work-up - American Family Physician
Apr 15, 2008 - Primary care physicians are often asked about easy bruising, excessive bleeding, or risk of bleeding before surgery. A thorough history, including a family history, will guide the appropriate work-up, and a physical examination may provide clues to diagnosis. A standardized bleeding ...
American Family Physician : Article
https://www.aafp.org/afp/2008/0415/p1117.html
Lymphadenopathy: Differential Diagnosis and Evaluation - American Family Physician
Oct 15, 1998 - Although the finding of lymphadenopathy sometimes raises fears about serious illness, it is, in patients seen in primary care settings, usually a result of benign infectious causes. Most patients can be diagnosed on the basis of a careful history and physical examination. Localized ...
American Family Physician : Article
https://www.aafp.org/afp/1998/1015/p1313.html
Leukocytosis: Basics of Clinical Assessment - American Family Physician
Nov 1, 2000 - Leukocytosis, a common laboratory finding, is most often due to relatively benign conditions (infections or inflammatory processes). Much less common but more serious causes include primary bone marrow disorders. The normal reaction of bone marrow to infection or inflammation leads to ...
American Family Physician : Article
https://www.aafp.org/afp/2000/1101/p2053.html
Evaluating the Child with Purpura - American Family Physician
Aug 1, 2001 - Purpura is the result of hemorrhage into the skin or mucosal membrane. It may represent a relatively benign condition or herald the presence of a serious underlying disorder. Purpura may be secondary to thrombocytopenia, platelet dysfunction, coagulation factor deficiency or vascular ...
American Family Physician : Article
https://www.aafp.org/afp/2001/0801/p419.html
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