Metformin to Prevent Diabetes in Patients at Increased Risk - Cochrane for Clinicians -...
Nov 1, 2020 - In patients at increased risk of developing type 2 diabetes, metformin reduces the risk (number needed to treat [NNT] = 7; 95% CI, 6 to 10) compared with counseling on standard diet and exercise.
American Family Physician : Cochrane for Clinicians
https://www.aafp.org/afp/2020/1101/p531.html
Aromatase Inhibitors Such as Letrozole (Femara) vs. Clomiphene (Clomid) for Subfertile ...
May 1, 2019 - When treated with letrozole, subfertile women with PCOS who are trying to conceive have increased chances of pregnancy (number needed to treat [NNT] = 11) and live birth (NNT = 10) compared with those treated with clomiphene.
American Family Physician : Cochrane for Clinicians
https://www.aafp.org/afp/2019/0501/p545.html
DPP-4 Inhibitors and GLP-1 Receptor Agonists for Prevention or Delay of Type 2 Diabetes...
Apr 1, 2018 - There is only limited-quality evidence that at-risk patients taking GLP-1 receptor agonists are less likely to progress to diabetes (number needed to treat [NNT] = 23). Serious adverse events were more likely in patients taking GLP-1 receptor agonists than in patients taking placebo ...
American Family Physician : Cochrane for Clinicians
https://www.aafp.org/afp/2018/0401/p437.html
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