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Triple Inhaled Therapy Provides a Small Reduction in Moderate COPD Exacerbations, No ... Restricted content. Login required.

Jan 15, 2021 - Triple inhaled therapy, with budesonide (Pulmicort) in a dose of either 160 mcg or 320 mcg daily plus a long-acting muscarinic antagonist (LAMA) and a long-acting beta2 agonist (LABA), reduces moderate exacerbations (a need for an antibiotic or steroid for three or more days) more than ...

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0115/od2.html

Short-Term Low Back Pain Relief with Placebo - POEMs - American Family Physician Restricted content. Login required.

Jan 15, 2021 - Over three weeks, patients with long-term low back pain who knowingly took placebo twice a day reported less pain and disability than those continuing with treatment as usual.

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0115/od3.html

Twenty-Year Follow-Up of Women's Health Initiative Trials: Lower Breast Cancer ... Restricted content. Login required.

Jan 15, 2021 - The cumulative 20-year follow-up report from the Women's Health Initiative hormone therapy trials found significantly lower breast cancer incidence and mortality among postmenopausal women who previously took conjugated equine estrogen (CEE; Premarin) alone (with a prior hysterectomy) ...

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0115/od1.html

Buffering Lidocaine 1%/ Epinephrine with Sodium Bicarbonate in a 3:1 Ratio Is as ... Restricted content. Login required.

Jan 15, 2021 - Lido/Epi buffered with NaHCO3 in a 3:1 ratio is significantly less painful during infiltration than unbuffered Lido/Epi and buffered Lido/Epi in a 9:1 ratio.

American Family Physician : POEMs

https://www.aafp.org/afp/2021/0115/od4.html

Fecal Occult Blood Testing Is Inaccurate as Part of Diagnostic Workup - POEMs - ... Restricted content. Login required.

Dec 1, 2020 - In this well-conducted systematic review, FOBT, although useful in screening for colorectal cancer, is not highly accurate in evaluating patients with clinical indications.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/1201/p692.html

Some Drugs Slightly Improve Cognition in People with Dementia; Effects on Behavioral or... Restricted content. Login required.

Dec 1, 2020 - Some treatments can improve cognition on research scales, but daily function will not be affected in a noticeable way. Managing behavioral or psychological issues with medication is not supported by current evidence

American Family Physician : POEMs

https://www.aafp.org/afp/2020/1201/p694.html

Easy Rule Identifies Patients with Low-Risk Penicillin Allergies - POEMs - American ... Restricted content. Login required.

Dec 1, 2020 - A label of penicillin allergy clears the shelves of many effective treatments for various infections. A simple rule outlined in the synopsis effectively identifies (without allergy testing) low-risk penicillin allergies in patients with a history of a penicillin allergy event.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/1201/p692a.html

Vaginal Bleeding Decreases over Time with a Levonorgestrel Intrauterine System - POEMs ... Restricted content. Login required.

Dec 1, 2020 - Bleeding decreased over time for most women after the insertion of a levonorgestrel-releasing intrauterine system.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/1201/p693.html

Antibiotic and Corticosteroid Treatment Effective for Acute Exacerbations of COPD - ... Restricted content. Login required.

Nov 15, 2020 - Short-term antibiotic treatment and short-term systemic corticosteroids are both associated with a faster resolution of COPD symptoms and fewer treatment failures.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/1115/od2.html

A Specific Probiotic Decreases Crying in Infants Younger than Two Months with Colic - ... Restricted content. Login required.

Nov 15, 2020 - Is probiotic supplementation effective in decreasing crying in infants with colic?

American Family Physician : POEMs

https://www.aafp.org/afp/2020/1115/od5.html

Low-Dose Aspirin Beneficial for the Prevention of Preterm Birth in Nulliparous Patients... Restricted content. Login required.

Nov 15, 2020 - The routine use of low-dose aspirin, 81 mg daily, starting as early as six weeks' gestational age provided a statistically significant absolute risk reduction (nearly 2 percentage points) in the incidence of preterm birth among nulliparous patients with singleton gestation in ...

American Family Physician : POEMs

https://www.aafp.org/afp/2020/1115/od4.html

Watch-and-Wait Strategy Is an Option for Primary Spontaneous Pneumothorax - POEMs - ... Restricted content. Login required.

Nov 15, 2020 - Conservative observation of patients presenting with a first primary spontaneous pneumothorax is as effective as immediate chest tube insertion in achieving full lung re-expansion at eight weeks.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/1115/od3.html

Terbinafine and Itraconazole Are Most Effective for Toenail Onychomycosis - POEMs - ... Restricted content. Login required.

Oct 15, 2020 - For toenail onychomycosis, continuous terbinafine (Lamisil), 250 mg, and continuous itraconazole (Sporanox), 200 mg, for 12 to 24 weeks are the preferred therapies.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/1015/od5.html

C-Reactive Protein Is the Most Useful Biomarker for Diagnosis of Outpatient CAP - POEMs... Restricted content. Login required.

Oct 15, 2020 - This review found that the best evidence supports C-reactive protein as the most useful and accurate biomarker for diagnosing CAP in adults presenting with lower respiratory tract symptoms.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/1015/od6.html

Cycled Hyperbaric Oxygen Improves the Healing of Diabetic Foot Ulcers - POEMs - ... Restricted content. Login required.

Oct 15, 2020 - Hyperbaric oxygen provided with a device that cycles oxygen from high pressure to low pressure increased the likelihood of complete healing of diabetic foot ulcers when combined with standard dressing and an offloading boot.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/1015/od3.html

Increased Daily Steps Associated with Reduced All-Cause Mortality - POEMs - American ... Restricted content. Login required.

Oct 15, 2020 - This study found that a greater number of daily steps was significantly associated with lower all-cause mortality.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/1015/od4.html

Denosumab No Better than Bisphosphonates for Preventing Fracture, and the Cost Is Much ... Restricted content. Login required.

Sep 15, 2020 - This meta-analysis found no evidence that the monoclonal antibody denosumab reduces the risk of fracture more than bisphosphonates.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0915/p375a.html

Fecal Microbiota Transplant Effective for Irritable Bowel Syndrome - POEMs - American ... Restricted content. Login required.

Sep 15, 2020 - This is the largest and best study to date of fecal microbiota transplant for irritable bowel syndrome —with impressive results.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0915/p377.html

ACR Guideline for Managing Patients with Degenerative Joint Disease of the Hand, Knee, ... Restricted content. Login required.

Sep 15, 2020 - This meta-analysis found no evidence that the monoclonal antibody denosumab reduces the risk of fracture more than bisphosphonates.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0915/p376.html

Similar Long-Term Morbidity and Mortality with Human Insulin and Analogue Insulin - ... Restricted content. Login required.

Sep 15, 2020 - This study found no difference in long-term patient-oriented outcomes between human and analogue insulins in adults with type 2 diabetes.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0915/p375.html

Daily Colchicine Post-MI Reduces Strokes and Recurrent Hospitalizations for Angina - ... Restricted content. Login required.

Aug 15, 2020 - Daily colchicine after MI reduces cardiovascular events, specifically strokes and hospitalizations for angina. It is inexpensive and well-tolerated and should be considered for patients with recent MIs who are already using guideline-directed therapy.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0815/p248.html

Oseltamivir of Uncertain Benefit in Patients with Flulike Symptoms - POEMs - American ... Restricted content. Login required.

Aug 15, 2020 - Although the authors report that compared with usual care oseltamivir shortens the duration of symptoms, the methodologic biases in this study make their conclusions suspect.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0815/p248a.html

Small Reduction in Cardiovascular Outcome After Ischemic Stroke with Lower LDL Target, ... Restricted content. Login required.

Aug 15, 2020 - A lower LDL target slightly reduced the likelihood of a broad composite outcome (number needed to treat [NNT] = 43 over 3.5 years), largely by reducing nonfatal strokes (NNT = 77; statistical significance not reported).

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0815/p247.html

Rates of Adverse Effects of Treatment for Otitis Media Vary by Antibiotic and Dose - ... Restricted content. Login required.

Aug 1, 2020 - The rates of diarrhea and rashes associated with the treatment of children with acute otitis media vary depending on each specific antibiotic and its dosing. The rates of diarrhea and generalized rash were highest with amoxicillin/clavulanate (Augmentin) and high-dose amoxicillin, and ...

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0801/p186.html

Increasing the D-dimer Threshold for Patients with Low Clinical Pretest Probability ... Restricted content. Login required.

Jul 15, 2020 - The Pulmonary Embolism Graduated d-Dimer strategy increases the number of patients in the emergency department and outpatient setting who have PE ruled out via d-dimer testing, thus decreasing the need for chest imaging.

American Family Physician : POEMs

https://www.aafp.org/afp/2020/0715/p117a.html

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