Direct Oral Anticoagulants vs. Warfarin to Prevent Stroke and Embolic Events in ...
Apr 1, 2019 - Direct oral anticoagulants are as likely as warfarin to prevent all strokes and systemic embolic events in patients with atrial fibrillation and CKD stage 3. They do not increase the risk of major bleeding events. The evidence remains insufficient to make recommendations for the use of ...
American Family Physician : Cochrane for Clinicians
https://www.aafp.org/afp/2019/0401/p422.html
DPP-4 Inhibitors and GLP-1 Receptor Agonists for Prevention or Delay of Type 2 Diabetes...
Apr 1, 2018 - There is only limited-quality evidence that at-risk patients taking GLP-1 receptor agonists are less likely to progress to diabetes (number needed to treat [NNT] = 23). Serious adverse events were more likely in patients taking GLP-1 receptor agonists than in patients taking placebo ...
American Family Physician : Cochrane for Clinicians
https://www.aafp.org/afp/2018/0401/p437.html
Effectiveness and Safety of Factor Xa Inhibitors in Patients with Atrial Fibrillation -...
Oct 1, 2019 - Treatment of AFib with a factor Xa inhibitor results in a decrease in the combined end point of stroke and embolic events (odds ratio [OR] = 0.89; 95% CI, 0.82 to 0.97), as well as a decrease in intracranial hemorrhage (OR = 0.50; 95% CI, 0.42 to 0.59) and all-cause mortality (OR = ...
American Family Physician : Cochrane for Clinicians
https://www.aafp.org/afp/2019/1001/p405.html
Effectiveness of PPAR Gamma Agonists in Preventing Recurrent Stroke and Other Vascular ...
Sep 1, 2020 - PPAR gamma agonists are probably effective in preventing recurrent stroke in people with previous stroke or TIA.
American Family Physician : Cochrane for Clinicians
https://www.aafp.org/afp/2020/0901/p271.html
General Health Checks in Adults for Reducing Disease-Related Morbidity and Mortality - ...
Dec 1, 2019 - General health check visits have no benefit on cardiovascular morbidity or on total, cardiovascular, or cancer-related mortality. There is also no evidence that they cause patient harm.
American Family Physician : Cochrane for Clinicians
https://www.aafp.org/afp/2019/1201/p676.html
Metformin to Prevent Diabetes in Patients at Increased Risk - Cochrane for Clinicians -...
Nov 1, 2020 - In patients at increased risk of developing type 2 diabetes, metformin reduces the risk (number needed to treat [NNT] = 7; 95% CI, 6 to 10) compared with counseling on standard diet and exercise.
American Family Physician : Cochrane for Clinicians
https://www.aafp.org/afp/2020/1101/p531.html
OnabotulinumtoxinA for Prevention of Migraine in Adults - Cochrane for Clinicians - ...
Feb 1, 2020 - OnabotulinumtoxinA reduces the number of migraine days per month by two days compared with placebo in adults with chronic migraines.
American Family Physician : Cochrane for Clinicians
https://www.aafp.org/afp/2020/0201/p144.html
Preventing or Delaying Type 2 Diabetes Mellitus with Diet and Exercise - Cochrane for ...
Dec 1, 2018 - There is moderate-quality evidence that in patients with impaired glucose tolerance (IGT) defined by an abnormal 75-g two-hour glucose tolerance test, implementing changes in diet and adding physical activity together can prevent or delay the development of type 2 diabetes.
American Family Physician : Cochrane for Clinicians
https://www.aafp.org/afp/2018/1201/p643.html
Smoking Cessation with Text Messaging and App-Based Interventions - Cochrane for ...
Aug 1, 2020 - Automated text messaging interventions are more effective than minimal smoking cessation support (absolute risk reduction [ARR] = 3%; 95% CI, 1% to 5%).
American Family Physician : Cochrane for Clinicians
https://www.aafp.org/afp/2020/0801/p148.html
Use of Niacin for Primary or Secondary Prevention of Cardiovascular or Cerebrovascular ...
Apr 1, 2018 - Prescription niacin (nicotinic acid, vitamin B3) does not reduce myocardial infarctions, strokes, or overall mortality when used for primary or secondary prevention.
American Family Physician : Cochrane for Clinicians
https://www.aafp.org/afp/2018/0401/p436.html
Vaccines for Preventing Influenza in Healthy Children, Healthy Adults, and Older Adults...
Aug 1, 2019 - Influenza vaccination reduces rates of laboratory-confirmed influenza and symptomatic influenza-like illness in healthy children, healthy adults, and older adults. There is no consistent evidence that influenza vaccination reduces school absenteeism in children, parental absenteeism ...
American Family Physician : Cochrane for Clinicians
https://www.aafp.org/afp/2019/0801/p143.html
Vitamin and Mineral Supplementation for Maintaining Cognitive Functioning in ...
Mar 1, 2020 - Vitamin and mineral supplementation has little to no beneficial effect on preserving cognitive functioning or preventing dementia in cognitively healthy adults 40 years and older.
American Family Physician : Cochrane for Clinicians
https://www.aafp.org/afp/2020/0301/p272.html
navigate_before 1 navigate_next