THOMAS G. ZIMMERMAN
Although Barrett esophagus is a risk factor for esophageal adenocarcinoma, its management and the need for screening or surveillance endoscopy remain controversial. Screening endoscopy should be considered for patients with multiple risk factors, and those who have high-grade...
TIMOTHY D. PELKOWSKI, ANTHONY J. VIERA
Celiac disease is an autoimmune disorder involving chronic inflammation of the small intestinal mucosa after exposure to dietary gluten. The diagnosis requires confirmation with serologic testing and, in most cases, small bowel biopsy. Treatment consists of a lifelong gluten...
KENNETH S. YEW
Tinnitus is commonly associated with hearing loss, although other possible etiologies include cerumen impaction, middle ear effusion, otosclerosis, and use of certain medications. Diagnosis is based on the patient history, as well as physical examination of the eyes, ears,...
TINA FAN, DARLENE P. SMALLMAN
A 60-year-old man presents to your office for routine follow-up and medication refills for hyperlipidemia and hypertension. His blood pressure is 130/80 mm Hg, and his fasting lipid panel reveals a total cholesterol level of 220 mg per dL and a high-density lipoprotein...
DANIEL F. McCARTER
The popularity and increased availability of gluten-free foods allow patients with celiac disease to lead a more normal lifestyle. It is important to understand that in the absence of gluten-related symptoms, a gluten-free diet is not synonymous with healthy and may only add...
E. GRILLO, A. MIGUEL-MORRONDO, P. JAÉN-OLASOLO
Photo Quiz presents readers with a clinical challenge based on a photgraph or other image.
CMS' New Meaningful Use Timeline Leaves Stage 2 Requirements Unchanged | Physician Groups Protest VA's Attempt to Expand APRNs' Scope of Practice | AHRQ Publishes Guide to Help Practices Implement Health Assessment Programs | <i>M<sc>ed</sc>W<sc>atch</sc></i>: FDA Lifts...
ROB BUTLER, RAGHAVAKURUP RADHAKRISHNAN
What are the effects of treatments on cognitive, behavioral, and psychological symptoms of dementia (Alzheimer disease, Lewy body dementia, or vascular dementia)?
MARK A. GRABER, ROBERT DACHS, JILL ENDRES
It seems to be safe to lower systolic blood pressure to a target of 140 mm Hg in those with an acute hemorrhagic stroke. However, there seems to be no clinical benefit to this approach when the data are adjusted for baseline NIH Stroke Scale scores.
ERIKO ONISHI, FRANCES BIAGIOLI, SARAH SAFRANEK
No recent evidence demonstrates that methylphenidate improves fatigue in patients receiving palliative care. Methylphenidate can be used to minimally improve fatigue symptom scores in patients with cancer-related fatigue.
ALLEN F. SHAUGHNESSY
Over five years, treatment with metformin for three years, with other hypoglycemics as needed, reduced the likelihood of death, nonfatal stroke, or the need for vascularization compared with treatment beginning with glipizide (Glucotrol). Cardiovascular events were not...
ALLEN F. SHAUGHNESSY
Taken in aggregate, symptoms of depression do not improve in patients with low vitamin D levels when given vitamin D supplementation any more than when given placebo. There may be a benefit in patients with low vitamin D levels and mild to moderate depression.
This review of all available data found a significantly increased risk of bladder cancer among adults with type 2 diabetes treated with pioglitazone. Pioglitazone also significantly increases the risk of heart failure, and there is minimal, if any, patient-oriented evidence...
In April 2013, the American Urological Association (AUA) released a guideline on early detection of prostate cancer, namely to reduce prostate cancer mortality.
The U.S. Preventive Services Task Force (USPSTF) recommends against screening with resting or exercise electrocardiography (ECG) for the prediction of coronary heart disease (CHD) events in asymptomatic adults at low risk of CHD events.
Tinnitus (TIN-ih-tus) is a sound you may hear when there is not sound coming from a source outside your body. It is not usually a serious condition, but it can be annoying. It may sound like a ringing, buzzing, or clicking inside your head. When it is very quiet, tinnitus can...
Celiac (SEE-lee-ack) disease is swelling in the gut that is caused by eating gluten. Gluten is a protein in foods made with wheat, rye, or barley. The swelling stops your body from getting the nutrients it needs. This disease can occur at any age. About one in 100 people has it.
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