• Articles

    Cervical Cancer Screening

    Caitlyn M. Rerucha, Rebecca J. Caro, Vernon L. Wheeler

    Precancerous cervical lesions and cervical carcinomas are strongly associated with sexually-transmitted high-risk human papillomavirus (HPV) infection, which causes almost all cervical cancers. Screening with cytology can detect early cervical cancer precursors and early...

    Cervical Cancer: Evaluation and Management

    Jennifer Wipperman, Tara Neil, Tracy Williams

    Most cervical cancer risk factors relate to increased exposure to human papillomavirus or decreased ability to clear the virus immunologically. Cervical cancer may be detected after a Papanicolaou test result is abnormal, a lesion is visualized on pelvic examination, or...

    Rheumatoid Arthritis: Common Questions About Diagnosis and Management

    Amy Wasserman

    Patients with rheumatoid arthritis typically present with pain and stiffness in multiple joints, often the wrists, proximal interphalangeal joints, and metacarpophalangeal joints. Some patients may experience extra-articular manifestations affecting the eyes, skin, lungs, and...


    Putting Choosing Wisely into Practice

    Jennifer L. Middleton

    It is our responsibility as physicians to help our patients avoid interventions that are not helpful or, worse, potentially harmful.

    AAFP News Now: AFP Edition

    AAFP News: AFP Edition

    AAFP Warns Labor Department Against Expanding Association Health Plans | AAFP Gives CMS Feedback on Prior Authorizations, Opioid Epidemic | Initial ABFM Certification Window Closing for Some Family Physicians | New Tool Guides Family Physicians Looking to Open a Practice

    Cochrane for Clinicians

    Use of Niacin for Primary or Secondary Prevention of Cardiovascular or Cerebrovascular Events

    Joseph R. Yancey, Jeanmarie B. Rey

    Prescription niacin (nicotinic acid, vitamin B3) does not reduce myocardial infarctions, strokes, or overall mortality when used for primary or secondary prevention.

    DPP-4 Inhibitors and GLP-1 Receptor Agonists for Prevention or Delay of Type 2 Diabetes Mellitus and Associated Complications

    Dustin K. Smith, Matthew J. Wessner

    There is only limited-quality evidence that at-risk patients taking GLP-1 receptor agonists are less likely to progress to diabetes (number needed to treat [NNT] = 23). Serious adverse events were more likely in patients taking GLP-1 receptor agonists than in patients taking...

    Medicine by the Numbers

    Pneumococcal Vaccines in Chronic Obstructive Pulmonary Disease

    Zachariah Clark, Douglas Maurer

    Pneumococcal vaccines had no significant effect on mortality from cardiorespiratory disease when compared with control and had no significant effect on all-cause mortality. Find out more.

    Photo Quiz

    Digital Clues

    Rob Danoff, Julia Todd

    An older man presented with increasing fatigue and fingernail deformity.


    Helping Patients Live with Chronic Pain

    Justin Van Hoorebeke, Adriel Kramer, Justin Van Hoorebeke, Adriel Kramer

    Providing high-quality, patient-centered care for those living with chronic pain includes developing a good understanding of the many ways the pain affects their lives are affected by their symptoms and validating their concerns and feelings.


    Clinical Diagnosis of Lyme Disease Frequently Misses the “Bull's Eye”

    Allen F. Shaughnessy

    Broad-Spectrum Antibiotics Increase Adverse Events in Children with Acute Respiratory Infections with Minimal Benefit

    David Slawson

    Broad-spectrum antibiotics are no more effective than narrow-spectrum antibiotics for treating acute respiratory tract infections in infants and children, and adverse events are significantly more common in children treated with broad-spectrum antibiotics.

    Early PT for Acute Low Back Pain Is Cost-Effective, but Gain in Quality of Life Is Likely Too Small to Notice

    Mark H. Ebell

    At $30,000 per quality-adjusted life year (QALY) gained, early PT for acute low back pain in primary care is cost-effective by the usual criteria of $50,000 to $100,000 per QALY. However, the magnitude of improvement in quality of life is small and is probably not clinically...

    Practice Guidelines

    Syncope Evaluation and Treatment Guidelines from ACC, AHA, and HRS

    Lisa Hauk

    The American College of Cardiology (ACC), American Heart Association (AHA), and Heart Rhythm Society (HRS) have released guidelines to assist physicians in evaluating and treating syncope.

    FPIN's Help Desk Answers

    Duration of Bisphosphonate Therapy

    Helen C. Lam, Christie M. Thomas, Julia M. Shaver

    Oral bisphosphonates significantly reduce clinical fracture risk at four years in women with postmenopausal osteoporosis (T-score less than -2.5). Treatment beyond five years is associated with further reductions in fractures in women with persistent femoral neck T-scores...

    Short-Term Antipsychotics for Alzheimer Disease

    Alice Zhang, Robert Martin

    Physicians should consider not using antipsychotics in patients with dementia. Patients with dementia, including Alzheimer disease, who are treated with antipsychotics for any length of time have a higher mortality rate than those not taking antipsychotics.


    All editors in a position to control content for this activity, AFP journal, are required to disclose any relevant financial relationships. View disclosures.

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