• Articles

    Tickborne Diseases: Diagnosis and Management

    Emma J. Pace, Matthew O'Reilly

    The incidence of tickborne disease is increasing in the United States. Patients presenting with flulike symptoms during the spring and summer months should be evaluated for a tickborne disease. Treatment based on experience and observation is recommended for tickborne...

    Chronic Dyspnea: Diagnosis and Evaluation

    Nitin Budhwar, Zubair Syed

    Dyspnea is a symptom resulting from various diseases and physiologic states. It is commonly seen in primary care and is considered chronic if present for more than one month. Disease states involving cardiac or pulmonary systems are the likeliest causes of dyspnea. The...

    Endometrial Biopsy: Tips and Pitfalls

    Pamela M. Williams, Heidi L. Gaddey

    Endometrial biopsy is a safe and efficient method to evaluate the endometrium. Endometrial biopsy is highly specific for diagnosing atypical hyperplasia and endometrial cancer in postmenopausal women. The biopsy is performed using a catheter that is inserted through the...


    AFP's Approach to COVID-19

    Sumi Sexton

    At the end of February, my practice started planning for the impact of coronavirus disease 2019 (COVID-19) without fully understanding what was to come. Thinking we were ahead of the game, I was proud of the presentation my partner created for our office and naively thought...

    AFP Clinical Answers

    Blood Pressure Readings, Tonsillectomy in Children, Venous Ulcers, Opioids, Pelvic Inflammatory Disease

    Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.

    Cochrane for Clinicians

    Antidepressants Plus Benzodiazepines for Adults with Major Depression

    Margot Savoy

    A combination of tricyclic antidepressants and benzodiazepines is more effective for major depression in adults than tricyclic antidepressants alone in the first four weeks of treatment.

    Lithium for Acute Mania

    Spencer Dean, Kristian Sanchack

    Lithium is more effective at inducing a reduction of at least 50% on the validated Young Mania Rating Scale compared with placebo (number needed to treat [NNT] = 6; 95% CI, 5 to 8; six studies; n = 1,707).

    Implementing AHRQ Effective Health Care Reviews

    Therapies for COPD Exacerbations in Adults

    Aaron Saguil

    What are the benefits and harms of pharmacologic and nonpharmacologic treatments for exacerbations of chronic obstructive pulmonary disease (COPD) in adults?

    Diagnostic Tests

    IBSchek for Irritable Bowel Syndrome

    Pamela O. Obi

    IBSchek is a blood test marketed to assist in the diagnosis of irritable bowel syndrome with predominant diarrhea (IBS-D) or with mixed bowel habits (IBS-M) in adults.

    Photo Quiz

    Lower Extremity Petechiae and Purpura

    Jon M. Sweet, Benjamin H. Mulkey

    A patient presented with a nontender, symmetrical petechial and purpuric rash from the soles to the lower abdomen.

    Practice Guidelines

    Migraines in Children: Recommendations for Acute and Preventive Treatment

    Lindsey E. Hoover

    Updated recommendations for the prevention and treatment of migraines in children and adolescents were recently published by the American Academy of Neurology and the American Headache Society, and they are based on a systematic review of new evidence published between...

    FPIN's Clinical Inquiries

    Megestrol for Palliative Care in Patients with Cancer

    Meagan Wong, Mariatou Sisay, Jon O. Neher, Sarah Safranek

    Megestrol may be considered as a component of palliative care nutritional support in patients with cancer.

    Medicine by the Numbers

    Tranexamic Acid for Postpartum Hemorrhage

    Eric Tang, Jessica Stetz

    Postpartum hemorrhage is the most common cause of maternal death worldwide. Tranexamic acid is an antifibrinolytic agent that has shown to decrease bleeding in surgical patients and all-cause death in trauma patients. Does early administration of tranexamic acid reduce the...

    Information from Your Family Doctor

    Ticks: How to Protect Yourself

    Avoiding ticks and places where ticks may be is the best way to keep from getting sick from a tick bite. After being outside in places with ticks, carefully check yourself and family members for ticks (Figure 1). Children should be checked with extra care. Properly and...

    Endometrial Biopsy

    Endometrial biopsy is a safe and effective way to evaluate the tissue that lines the inside of the uterus (or womb). A thin plastic tube called a catheter is placed into the uterus, and a small amount of the lining is suctioned into the device. This method provides a tissue...


    All editors in a position to control content for this activity, AFP journal, are required to disclose any relevant financial relationships. View disclosures.

    Tag Legend


    CME Continuing Medical Education Credit
    POC Point-of-Care Resource
    FREE Free Access
    Alg Algorithm
    DDx Differential Diagnosis
    PtEd Patient Education