• Articles

    Atopic Dermatitis: Diagnosis and Treatment

    Winfred Frazier, Namita Bhardwaj

    Atopic dermatitis, a chronic relapsing and remitting inflammatory skin disease affecting 10% of the population, is caused by a complex interaction of immune dysregulation, epidermal gene mutations, and environmental factors that disrupts the epidermis and leads to intensely...

    Ectopic Pregnancy: Diagnosis and Management

    Erin Hendriks, Rachel Rosenberg, Linda Prine

    Ectopic pregnancy occurs when a fertilized ovum implants outside of the uterine cavity. It should be considered in any patient presenting early in pregnancy with vaginal bleeding or lower abdominal pain in whom intrauterine pregnancy has not yet been established. Patient...

    Top 20 Research Studies of 2019 for Primary Care Physicians

    Mark H. Ebell, Roland Grad

    The annual installment of this series summarizes the top studies of 2019. These studies were summarized as POEMs (patient-oriented evidence that matters) and were highly rated by Canadian Medical Association members for their clinical relevance and expected health benefits to...


    Why the Stress-Disease Connection Matters and How to Respond

    Jennifer L. Middleton

    Emotional health and physical health are deeply intertwined, and patients who have experienced difficult events or persistent stressors may struggle to cope in a healthy way. Helping our patients recognize the connection between physical and mental well-being allows us to...

    AFP Clinical Answers

    Hirsutism, Amphetamines, COVID-19 Viral Shedding, Hand-Foot-and-Mouth Disease

    Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.


    Segesterone Acetate and Ethinyl Estradiol Vaginal Ring (Annovera) for Contraception

    Amy L. Lee

    Annovera is an effective combined progestin/estrogen contraceptive device that can be used for one year.

    Putting Prevention Into Practice

    Screening for Abdominal Aortic Aneurysm

    Iris Mabry-Hernandez, Andrew Mock

    A 65-year-old man with no significant medical history presents to your clinic for a wellness visit. His social history includes smoking periodically in his 20s, and his family history includes a father who died from an abdominal aortic aneurysm (AAA) in his 60s. The patient...

    Photo Quiz

    Severely Callused Hands and Feet

    Sam Longfellow, Elliott Courter

    A man presented with a long history of an uncontrollable, proliferating skin callus formation on both hands and feet.

    Curbside Consultation

    The Older Driver

    Ranit Mishori, Oritsetsemaye Otubu

    Advancing age on its own is not a reason to stop driving. The ability to drive may enable older adults to maintain family and social interactions and to promote independence by accessing community resources, services, and volunteer opportunities.


    Autism Screening with Follow-Up Overidentifies Autism Spectrum Disorder

    Allen F. Shaughnessy

    Screening for ASD with the Modified Checklist for Autism in Toddlers with Follow-Up is effective in ruling out ASD in children who screen positive (negative predictive value of 98.6% at 2.2% prevalence).

    Surgery or Lasers Preferred to Foam Sclerotherapy for Varicose Veins

    Mark H. Ebell

    For symptomatic varicose veins at least 3 mm in diameter with evidence of saphenous vein reflux, laser ablation is the preferred initial therapy.

    Equivalent Pain Relief with Different Doses of Ibuprofen

    Allen F. Shaughnessy

    Higher doses of ibuprofen for acute pain relief offer no more benefit at 60 minutes than a single 400-mg dose. The same has been shown for chronic treatment of osteoarthritis. A higher, anti-inflammatory dose is not needed.

    Nonpharmacologic Approaches Are Better Than Medication to Control Aggression and Agitation in Dementia

    Allen F. Shaughnessy

    Nonpharmacologic approaches to agitation or aggression in patients with dementia are more effective than medication (e.g., haloperidol). Outdoor activities, multidisciplinary care, and massage and touch therapy with or without music are all effective.

    Practice Guidelines

    Heavy Menstrual Bleeding in Adolescents: ACOG Management Recommendations

    Laurie Costlow

    The American College of Obstetricians and Gynecologists (ACOG) has new recommendations and conclusions about menstrual bleeding disorders in adolescents.

    U.S. Preventive Services Task Force

    Screening for Abdominal Aortic Aneurysm: Recommendation Statement

    The USPSTF recommends 1-time screening for abdominal aortic aneurysm (AAA) with ultrasonography in men aged 65 to 75 years who have ever smoked.

    Letters to the Editor

    A Case of COVID-19 Infection: Chief Symptom, Diarrhea

    Matthew H. Meyers

    Care of the Military Veteran Should Include Screening for Substance Use Disorders



    Incorrect Title: In the Cochrane for Clinicians “Intrapartum Omega-3 Fatty Acid Intake and Length of Gestation,” (January 1, 2020, p. 17) the title of the department and the title of the accompanying table should have used antepartum rather than intrapartum. The correct title...


    All editors in a position to control content for this activity, AFP journal, are required to disclose any relevant financial relationships. View disclosures.

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