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Am Fam Physician. 2023;107(6):online

Author disclosure: No relevant financial relationships.

Details for This Review

Study Population: 8,805 patients with proven or suspected acute bacterial conjunctivitis

Efficacy End Points: Clinical effectiveness (i.e., clinical cure); resolution of at least two of the following three signs after a course of antibiotic therapy: bulbar conjunctival injection, palpebral conjunctival injection, and any purulent epiphora

Harm End Points: Antibiotic-associated ocular or systemic complications

Narrative: In the United States, acute conjunctivitis is estimated to occur in 6 million people annually, making up 1% of all primary care visits.1,2 Acute conjunctivitis can be caused by allergy or infection (bacterial, viral, and less commonly fungal).

BenefitsHarms
1 in 7 was helped (clinical cure after a course of antibiotics therapy)1 in 32 was harmed (experienced ocular adverse effects compared with placebo)
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Copyright ©2024 MD Aware, LLC (theNNT.com). Used with permission.

This series is coordinated by Christopher W. Bunt, MD, AFP assistant medical editor, and the NNT Group.

A collection of Medicine by the Numbers published in AFP is available at https:// www.aafp.org/afp/mbtn.

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