brand logo

Am Fam Physician. 2023;108(5):509-510

Author disclosure: No relevant financial relationships.

A 20-year-old man presented five days after developing odynophagia, rhinorrhea, and cough. His cough and rhinorrhea had improved without intervention, but the odynophagia had worsened. He also had dysuria and painful lesions on his lips. The patient did not have a history of similar episodes. He had not used any medications recently, including over-the-counter medications, and did not have a history of allergies.

There were superficial white plaques on his tongue that could be scraped off and superficial erosions and ulcerations on his lips and buccal surface (Figure 1). Physical examination also revealed bilateral conjunctival injection (Figure 2). A small erosion was present on his urethra. There was no other skin involvement.


Based on the patient's history and physical examination findings, which one of the following is the most likely diagnosis?

  • A. Behçet syndrome.

  • B. Erythema multiforme.

  • C. Reactive infectious mucocutaneous eruption.

  • D. Stevens-Johnson syndrome.

Already a member/subscriber?  Log In


From $165
  • Immediate, unlimited access to all AFP content
  • More than 130 CME credits/year
  • AAFP app access
  • Print delivery available

Issue Access

  • Immediate, unlimited access to this issue's content
  • CME credits
  • AAFP app access
  • Print delivery available
Purchase Access:  Learn More

The editors of AFP welcome submissions for Photo Quiz. Guidelines for preparing and submitting a Photo Quiz manuscript can be found in the Authors' Guide at To be considered for publication, submissions must meet these guidelines. Email submissions to

This series is coordinated by John E. Delzell Jr., MD, MSPH, associate medical editor.

A collection of Photo Quiz published in AFP is available at

Continue Reading

More in AFP

More in PubMed

Copyright © 2023 by the American Academy of Family Physicians.

This content is owned by the AAFP. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. This material may not otherwise be downloaded, copied, printed, stored, transmitted or reproduced in any medium, whether now known or later invented, except as authorized in writing by the AAFP.  See permissions for copyright questions and/or permission requests.