These key learning points summarize the consensus- and evidence-based recommendations included in this edition. The sources listed here for each statement recommend that physicians perform or implement these actions directly in a clinical setting.

1. For patients with fibromyalgia, use a multimodal management approach that emphasizes self-management and incorporates patient education, exercise, psychological therapies, and nonopioid drugs.
Evidence rating: SORT A
Source: Med Clin North Am, reference 2
Website: https://www.sciencedirect.com/science/article/abs/pii/S0025712520301243

2. Refer patients with myofascial pain syndrome for manual therapy (eg, deep tissue massage, integrated neuromuscular inhibition, myofascial release, post-isometric relaxation, spray and stretch technique) as a mainstay treatment.
Evidence rating: SORT C
Source: Pain Ther, reference 61
Website: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107879/pdf/40122_2013_Article_6.pdf

3. For patients with complex regional pain syndrome, start rehabilitation and physical therapy early in the course of the condition.
Evidence rating: SORT C
Source: National Institute of Neurological Disorders and Stroke (NINDS), reference 112
Website: https://www.ninds.nih.gov/health-information/disorders/complex-regional-pain-syndrome