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11 Tips for More Effective AI Clinical Searches

SUMANA REDDY, MD

FPM. 2026;33(3):12-16.

Author disclosure: no relevant financial relationships.

This content conforms to AAFP criteria for CME.

As new AI tools emerge, we must learn to critically evaluate their output while understanding that how we ask a question often determines the accuracy of the answer.

Dr. Reddy is a family physician and founder of Acacia Family Medical Group, an independent practice in Salinas, Calif.

Send comments to fpmedit@aafp.org, or add your comments to the article online.

Author disclosure: no relevant financial relationships.

  1. 1.FPM Topic Collection: Artificial Intelligence. FPM. Accessed April 6, 2026. https://www.aafp.org/fpm/topics/artificial-intelligence
  2. 2.Roustan D, Bastardot F. The clinicians’ guide to large language models: a general perspective with a focus on hallucinations. Interact J Med Res. 2025;14(1):e59823.
  3. 3.Wu D, Haredasht FN, Maharaj SK, et al. First, do NOHARM: towards clinically safe large language models. arXiv. 2025;preprint. https://arxiv.org/abs/2512.01241
  4. 4.National Library of Medicine. Develop a clinical question: using PICO to frame clinical questions. Accessed March 18, 2026. https://www.nlm.nih.gov/oet/ed/pubmed/pubmed_in_ebp/02-100.html
  5. 5.Savage T, Nayak A, Gallo R, Rangan E, Chen JH. Diagnostic reasoning prompts reveal the potential for large language model interpretability in medicine. NPJ Digit Med. 2024;7:20.
  6. 6.Welcome to the GRADE working group. Accessed March 18, 2026. https://www.gradeworkinggroup.org
  7. 7.Young RA, Martin CM, Sturmberg JP, et al. What complexity science predicts about the potential of artificial intelligence/machine learning to improve primary care. J Am Board Fam Med. 2024;37(2):332-345.

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