• Articles

    Targeted Therapies: A New Generation of Cancer Treatments

    DAVID E. GERBER

    The two main types of targeted therapy, monoclonal antibodies and small molecule inhibitors, have revolutionized the treatment of cancer. With their distinct mechanisms of action and toxicities, these drugs require new approaches to determine optimal dosing, to assess patient...

    Non-Neoplastic Epithelial Disorders of the Vulva

    THEODORE XAVIER O'CONNELL, LEENA SHANKAR NATHAN, WENDY ANN SATMARY, ANDREW T. GOLDSTEIN

    Epithelial disorders of the vulva include lichen sclerosus, lichen planus, and lichen simplex chronicus, the latter of which is the most common. Topical corticosteroids are used to treat all three of these disorders.

    Adolescent Substance Use and Abuse: Recognition and Management

    KIM S. GRISWOLD, HELEN ARONOFF, JOAN B. KERNAN, LINDA S. KAHN

    Screening for substance use is recommended for all adolescents. If screening is positive, physicians can conduct an in-depth evaluation or refer the patient to a subspecialist. Treatment involves multiple therapeutic components for the abuse and its comorbid disorders....

    Acute and Chronic Paronychia

    DIMITRIS RIGOPOULOS, GEORGE LARIOS, STAMATIS GREGORIOU, ALEVIZOS ALEVIZOS

    Treatment options for acute paronychia include warm compresses, topical antibiotics and corticosteroids, systemic antibiotics, and surgical incision and drainage. Treatment of underlying inflammation and infection is recommended, using a combination of a broad-spectrumtopical...

    AFP Journal Club

    Long-term PPI Therapy and the Risk of Hip Fracture

    MARK A. GRABER, ROBERT DACHS, ANDREA DARBY-STEWART

    Does the long-term use of PPIs increase the risk of hip fracture? The physician must balance the risks and benefits of PPIs, especially in certain patients.

    AAFP News Now: AFP Edition

    AAFP News Now: AFP Edition

    Bill Increases Funding for Some Primary Care Programs, Reduces Funding for Others | Foundation Releases Findings From its Report on Pay-for-Performance Initiatives | <b><i>MedWatch</i></b>: FDA Warns of Potential Adverse Effects from Bisphosphonate Use | New CPT Codes Added...

    Editorials

    The Era of Targeted Therapies

    MARGARET OFFERMANN

    Cancer has long been recognized as a disease process in which cells invade surrounding tissues and metastasize to distant sites. Multiple genetic and epigenetic mistakes occur as cells become cancerous, and some of these mistakes lead to the expression of proteins that aid in...

    Clinical Evidence Concise

    Gastroenteritis in Children

    JACQUELINE DALBY-PAYNE, ELIZABETH ELLIOT

    What are the effects of treatments for acute gastroenteritis?

    Photo Quiz

    An Abnormal Vaginal Opening in a Two-Year-Old

    NIKHIL HEMADY, DHARMESH SHAH

    Photo Quiz presents readers with a clinical challenge based on a photograph or other image.

    FPIN's Clinical Inquiries

    Medications for Insomnia Treatment in Children

    SARAH BABINEAU, CHERYL GOODWIN, BARBARA WALKER

    Melatonin may be effective for treating insomnia in healthy children and in those with physical or learning disabilities.

    Tips from Other Journals

    Knowledge of Correct Blood Culture Technique is Lacking

    KENNETH T. MOON

    Jet Lag: Treatment Options and Advice for Travelers

    ANNE D. WALLING

    Obesity and Obesity Management Not Being Documented

    AMY CRAWFORD-FAUCHER

    Curbside Consultation

    Combative Delirium

    RICHARD VIKEN

    In the context of their usual office or hospital settings, family physicians are not often called upon to deal with violent or hostile patients. However, just like advanced cardiac life support training prepares physicians for rare and unexpected cardiac arrest situations,...

    Practice Guidelines

    ACCP Revises Guideline on the Diagnosis of Lung Cancer

    AMBER HUNTZINGER

    The American College of Chest Physicians (ACCP) has revised its original guidelines for the diagnosis and management of lung cancer to update evidence supporting the original recommendations and to include additional relevant topics.

    Practice Guideline

    ACOG Releases Guidelines on Managing Herpes in Pregnancy

    LIZ HORSLEY

    The American College of Obstetricians and Gynecologists (ACOG) has released a practice bulletin to outline the spectrum of maternal and neonatal genital herpes infection and to provide guidelines on managing the infection during pregnancy.

    Letters to the Editor

    Postpartum Appendicitis Presenting as RUQ Pain

    ROGER K. GERSTLE

    Information from Your Family Doctor

    Skin Diseases of the Vulva: What You Should Know

    Lichen sclerosus (LIKE-en skler-OH-sus) is a skin problem that usually affects the vulva (the outside part of the vagina) or the anal area. Lichen simplex chronicus (LIKE-en SIM-pleks KRAH-neh-kus) is when the skin in and around the vulva gets thicker from constant itching...

    Chronic Paronychia: What You Should Know

    Paronychia (pair-oh-NIE-kee-ah) is a common problem that affects fingernails and toenails. It is caused by an infection of the skin around the nail. Chronic paronychia can happen after dish washing, finger sucking, trimming the cuticles too much, or frequent contact with...



    Disclosure

    All editors in a position to control content for this activity, AFP journal, are required to disclose any relevant financial relationships. View disclosures.


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