• Articles

    Lower Extremity Peripheral Artery Disease: Diagnosis and Treatment

    Jonathon M. Firnhaber, C.S. Powell

    Lower extremity peripheral artery disease (PAD) affects 12% to 60% of Americans 60 years and older, with significant risk factors being hypertension, diabetes mellitus, chronic kidney disease, and smoking. A 10-fold increase of PAD occurs with the presence of three or more of...

    Primary Care of Breast Cancer Survivors

    Kimberly Zoberi, Jane Tucker

    With declining breast cancer mortality rates, primary care physicians are treating more survivors. This care includes surveillance for cancer recurrence with history, physical examinations, and annual mammography. Breast cancer survivors often have sequelae from the disease...

    Right Care for Children: Top Five Do's and Don'ts

    Matthew Schefft, Alan R. Schroeder, Diane Liu, Daniel Nicklas, Justin Moher, Ricardo Quinonez

    The Lown Institute's Right Care Alliance Children's Health Council identified five “do” recommendations and five “don't” recommendations that highlight underuse and overuse in children's health care. These 10 examples of underuse and overuse were identified with the intent of...


    Downsides of Detecting Atrial Fibrillation in Asymptomatic Patients

    John Mandrola, Andrew Foy

    Despite the lack of outcomes evidence, the rise of wearable ECG sensors will cause many individuals to seek care for misdiagnosed AF. The best intervention for patients with correct diagnoses remains unclear. Primary care physicians must use their skills in discussing...

    AFP Clinical Answers

    Osteoporosis, Childhood Bullying, Rheumatoid Arthritis, Diabetes Counseling, Inhaled Steroids

    Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.

    Lown Right Care

    Coaching Patients About Successful Blood Pressure Management

    Ann Lindsay, Ajay Sharma, Alan Glaseroff

    A collaboration between AFP and the Lown Institute promotes a vision of delivering heath care that is based on the evidence, balanced in its approach, and focused on the patient.

    Putting Prevention Into Practice

    Screening for Atrial Fibrillation with Electrocardiography

    Howard Tracer, Rebecca Welch

    M.T. is a 67-year-old woman who presents to your office requesting electrocardiography (ECG). Her brother was recently diagnosed with atrial fibrillation after screening with ECG, and she is concerned that she may have the same condition.

    Photo Quiz

    Tongue Ulcer in a Young Child

    Samantha J. Bartling, Shayna C. Rivard

    A six-year-old boy presented with a painful ulcer on his tongue after receiving treatment at a dermatology clinic for foot lesions earlier in the day.


    Lofexidine (Lucemyra) for Treatment of Opioid Withdrawal Symptoms

    Carl Bryce

    Lofexidine has been shown to be as effective as clonidine at controlling some of the symptoms of withdrawal from opioid use. It may have a small additional benefit for maintaining abstinence in patients switched to buprenorphine or methadone for long-term maintenance.

    Practice Guidelines

    HIV Prevention and Treatment with ART: International Antiviral Society Updates Recommendations

    Lisa Croke

    Antiretroviral therapy is the key to preventing and managing human immunodeficiency virus infection. Based on the availability of new medications and treatment options, the USA Panel of the International Antiviral Society has updated its 2016 recommendations.

    U.S. Preventive Services Task Force

    Screening for Atrial Fibrillation with Electrocardiography: Recommendation Statement

    The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for atrial fibrillation with electrocardiography.


    Gabapentin and Pregabalin Not Effective for Low Back Pain with or Without Radiculopathy

    Mark H. Ebell

    The use of anticonvulsants like gabapentin (Neurontin) for painful conditions has increased greatly in recent years. This review finds good evidence that these drugs are not an effective treatment for low back pain with or without radiculopathy, and are associated with an...

    Increased Water Intake Decreases UTI Recurrence in Women

    Allen F. Shaughnessy

    Drinking an additional 1.5 liters per day of water halved the recurrence of UTI in women with a history of at least three episodes per year.

    Lorcaserin Is Safe, But Only Modestly Effective for Weight Loss

    Mark H. Ebell

    Lorcaserin, 10 mg twice daily, helps some patients lose 10% or more of their body weight (number needed to treat [NNT] = 10) and appears to be safe in terms of cardiovascular events.

    Aspirin Plus a High-Dose PPI Prevents Death and Progression in Patients with Barrett Esophagus

    Henry C. Barry

    In this study, patients with Barrett esophagus were less likely to die or develop esophageal cancer or high-grade dysplasia if they took high-dose esomeprazole (Nexium) alone or in combination with aspirin.

    Letters to the Editor

    Case Report: Efficient and Cost-Effective Diagnosis of Vaginitis


    All editors in a position to control content for this activity, AFP journal, are required to disclose any relevant financial relationships. View disclosures.

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